Clinical and radiographic evaluation of the effectiveness of treatment of apical periodontitis with the use of the author`s technique of vacuum-bolus irrigation of root canals

A device and techniques for vacuum-bolus irrigation of root canals are developed on the basis of the analysis of existing methods of medical treatment of root canals in endodontic treatment. A comparative assessment of the impact of different variables of vacuum on the degree of cleaning of the root canal model was carried out in an invitro experiment and the optimal values of vacuum and exposure time were pointed out. In the clinical part of the study 52 patients aged from 25 to 44 years with a diagnosis of apical periodontitis were treated and dynamically monitored during one year (the author`s vacuum-bolus technique was applied to 32 patients of the main study group in the course of endodontic irrigation of root canals; while 20 patients of the control group experienced a standard irrigation method with the use of endodontic syringe in the course of endodontic treatment). Criteria of the modified periapical index (PAI) were used to assess the efficacy of treatment. It was found that after 12 months, 90,5 % of patients of the main study group had no signs of demineralization of bone tissue, the orientation of bone trabeculae of cancellous bone and cortical plate were recovering. Thus, the vacuum-boluc irrigation of root canals can help us improve the efficiency of treatment of destructive forms of apical periodontitis.

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CLINICAL EFFECTIVENESS OF TREATMENT THE PATIENTS WITH CHRONIC APICAL PERIODONTITIS

International Journal of Medicine and Medical Research ◽

10.11603/ijmmr.2413-6077.2016.2.7037 ◽

2017 ◽

Author(s):

N. H. Gadzhula

Keyword(s):

Bone Destruction ◽

Clinical Effectiveness ◽

Complete Healing ◽

Main Group ◽

Apical Periodontitis ◽

Endodontic Treatment ◽

Control Group ◽

Filling Material ◽

Root Canals ◽

Antiseptic Treatment

Background. The success of endodontic treatment is provided by a thorough instrumental and antiseptic treatment of infected root canals, and it depends on the composition of filling material, the degree of adhesion to dentin, hermetic obturation of apical foramen, solubility of sealer.Objective. The study was aimed to evaluate the effectiveness of root canal obturation with BioRootTM RCS sealer in the treatment of patients with chronic apical periodontitis.Materials and methods. Endodontic treatment of 23 teeth in 20 patients with chronic apical periodontitis by method of lateral compaction of gutta-percha was carried out. In the main group root canals were obturated with BioRootTM RCS, in the control group the canals were filled with Apexit Plus. The percentage of efficient or non-efficient cases was evaluated on the basis of radiographic comparison of treated chronic apical periodontitis immediately after obturation, in three, six months and one year. Radiographic conditions were defined as existing state, improvement and worsening.Results. In a year of dynamic evaluation the final results were: in the main group – 54.55% of the patients had complete bone healing, in 27.27% of cases the focus of bone destruction was decreased by ½ or more of the initial sizes, 18.18% – resorption lesion was decreased by less than ½; in the control group – 33.33% of improvement, 25.0% of existing state and 41.66% of worsening.Conclusions. BioRootTM RCS using for root canals obturation in the treatment of chronic apical periodontitis we proved the high effectiveness of the treatment undertaken: complete healing or improvement of radiographic conditions of periapical bone destruction with X-ray signs of bone regeneration.

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How Did Prenatal Education Impact Women’s Perception of Pregnancy and Postnatal Life in a Romanian Population

Medicina ◽

10.3390/medicina57060581 ◽

2021 ◽

Vol 57 (6) ◽

pp. 581

Author(s):

Anca Maria Balasoiu ◽

Octavian Gabriel Olaru ◽

Romina Marina Sima ◽

Liana Ples

Keyword(s):

Prenatal Care ◽

Newborn Care ◽

Control Group ◽

Postnatal Life ◽

Study Group ◽

Prenatal Education ◽

Questionnaire Online ◽

A Prospective Study ◽

The Impact ◽

Official Information

Background and Objectives: Prenatal education represents an important part of maternal prenatal care in Western countries. In Romania, prenatal education is of recent interest but there is no official information about prenatal courses and their impact on prenatal care and patients in Romania. Material and methods: A prospective study based on the STROBE statement was designed in order to assess the prenatal education delivered in our unit. The study group included women who gave birth at Bucur Maternity, “Saint. John” Hospital, Bucharest, Romania and attended the prenatal courses, compared with a control group (women who gave birth in our unit but did not attend the prenatal lecture). Patients’ perception about the impact of prenatal education was collected by applying a questionnaire. Results: The analysis included 89 women who fulfilled the questionnaire online. In our study, 62 women (69.7%) attended the prenatal education classes and represented the study group while 27 women (30.3%) constituted the control group. Women who attended the prenatal lecture recognized the utility of the topic regarding newborn care (90.3%), while women from the control group did not consider it useful (n = 55.6%), χ2 = 18.412, p < 0.001. Patients from the study group admitted the importance of the topics (93.5%) from the lectures about breast feeding, while the percentage of these women from the control group is significantly lower (55.6%) χ2 = 27.867, p < 0.001. Conclusions: The benefits of prenatal education were recognized by women who attended the prenatal lecture, while women who did not participate underestimated the utility of the topics. Further actions are required to inform mothers about the necessity of antenatal education.

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Original Research. The Influence of Desquamative Gingivitis on Periodontal Health

Journal of Interdisciplinary Medicine ◽

10.1515/jim-2017-0011 ◽

2017 ◽

Vol 2 (s1) ◽

pp. 49-52 ◽

Cited By ~ 1

Author(s):

Monica Monea ◽

Tudor Hănțoiu ◽

Alexandra Stoica ◽

Ramona Vlad ◽

Alexandru Sitaru

Keyword(s):

Alveolar Bone ◽

Radiographic Evaluation ◽

Control Group ◽

Original Research ◽

Gingival Inflammation ◽

Periodontal Health ◽

Painful Condition ◽

Anterior Teeth ◽

Attached Gingiva ◽

The Impact

Abstract Background: Desquamative gingivitis (DG) is a non-plaque-induced, blistering and painful condition occurring most frequently on the labial aspect of the attached gingiva of anterior teeth. The incidence of DG is highest around 50 years of age, and usually indicates the presence of oral or systemic diseases. The purpose of our study was to determine the impact of DG on periodontal health by recording the plaque index, gingival index and gingival bleeding index in a group of patients with DG, compared to healthy controls. Materials and methods: Recordings of specific indices were performed in a group of 26 patients with DG and compared with 24 healthy individuals. These were followed by radiographic examinations in order to assess the loss of marginal alveolar bone. Results: The results showed that patients with DG had a statistically significant increase in periodontal indices, with more gingival inflammation and plaque retention compared to the control group (p <0.05). The highest scores for gingival inflammation were recorded in patients with DG, but on radiographic evaluation the difference was related only to gender, men being more affected by alveolar bone loss in both groups (p <0.05). Conclusions: The incidence and severity of gingival inflammation proved to be higher in patients with DG, which calls for better preventive and maintenance treatment protocols in this group of patients. Early diagnosis and initial-phase periodontal treatment are very important in preventing further tissue breakdown.

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Twin Pregnancies Complicated by a Single Malformed Fetus: Chorionicity, Outcome and Management

Twin Research and Human Genetics ◽

10.1375/twin.13.5.501 ◽

2010 ◽

Vol 13 (5) ◽

pp. 501-507 ◽

Cited By ~ 8

Author(s):

Ali Gedikbasi ◽

Alpaslan Akyol ◽

Gokhan Yildirim ◽

Ali Ekiz ◽

Ahmet Gul ◽

...

Keyword(s):

Gestational Age ◽

Statistical Significance ◽

Expectant Management ◽

Control Group ◽

Study Group ◽

Preliminary Evaluation ◽

Gestational Age At Birth ◽

The Impact ◽

Twin Pregnancies ◽

Age At Birth

The objective of this study was to evaluate the impact of one abnormal fetus in a twin pregnancy, to compare impact of chorionicity and clinical outcome of intervention and expectant management. Thirty-seven dichorionic (DC) twins and 18 monochorionic (MC) twins complicated with one malformed fetus were evaluated for gestational age, birthweight and perinatal outcome. Six hundred and forty-two twin pregnancies were evaluated in the database. The control groups consisted of 429 DC and 86 MC twins without anomalous fetus. Mean birthweight and gestational age at birth for DC control group were (n= 429; 2137g and 34.71 weeks), DC study group,n= 37; 2117g (p= .338) and 33.97 weeks (p= .311), and DC study group with major malformations,n= 30; 2019g (p= .289) and 33.3 weeks (p= .01), and showed only significance for gestational age. There was no statistical significance between MC control group,n= 86; 2097g and 34.93 weeks, and MC study group,n= 18; 2237g (p= .338), and 34.42 weeks (p= .502). Because of limited data, the preliminary evaluation for expectant management and intervention, and survival of at least one normal fetus showed no impact. We conclude that, although, all DC twin pregnancies have a risk for preterm delivery, DC twins complicated with major malformation of one twin, have a lower mean gestational age at birth. Preliminary results for intervention does not improve fetal outcome for DC and MC twins and needs further evaluation with greater studies of impact or review.

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Analysis of the Impact of Personalized Nursing Service and Hospice Care on the Quality of Life of Elderly Cancer Patients

Tobacco Regulatory Science ◽

10.18001/trs.7.4.24 ◽

2021 ◽

Vol 7 (4) ◽

pp. 469-473

Author(s):

Ting Fang ◽

Nian Wang ◽

Meng Chen ◽

Hongmei Ma

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Advanced Cancer ◽

Hospice Care ◽

Pain Treatment ◽

Control Group ◽

Study Group ◽

The Difference ◽

The Impact

Objective Explore the impact of personalized nursing services and hospice care on the quality of life of elderly patients with advanced cancer. Method We selected 80 elderly cancer patients admitted to our hospital from September 2020 to May 2021, and divided these patients into a study group and a control group using a random number table method. The patients in the control group used conventional nursing methods to treat and care for the patients, and the patients in the study group used hospice care measures and combined personalized nursing measures. The quality of life and pain treatment effects of the two groups of patients before and after treatment were compared. Result Before treatment, the quality-of-life scores of the two groups of patients were low, and there was no statistical difference (P>0.05); After treatment, the quality of life of the two groups of patients improved, but compared with the control group, the improvement was more obvious in the study group, and the difference was statistically significant (P<0.05). In terms of pain treatment effect, the total effective rate of pain treatment in the study group was 87.5%, which was significantly better than the 62.5% in the control group. The difference was statistically significant (P<0.05). Conclusion Personalized nursing services and hospice care are conducive to improving the survival and treatment of elderly patients with advanced cancer, and can be used as a clinical application program for the care of advanced cancer patients.

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Efficacy of Endodontic Treatment on the Persistence of Selected Endodontic Pathogens and on Radiographical Periapical Healing

Odovtos - International Journal of Dental Sciences ◽

10.15517/ijds.v17i2.22035 ◽

2015 ◽

Vol 17 (2) ◽

pp. 43

Author(s):

Rodolfo Zeledón DDS, Esp ◽

Carolina Ballestero DDS, Esp ◽

Erick Hernández DDS. Esp ◽

Tatiana Ramírez DDS, MSD ◽

Marianela Benavides DDS, Esp ◽

...

Keyword(s):

Positive Impact ◽

Fusobacterium Nucleatum ◽

Dental Students ◽

Apical Periodontitis ◽

Endodontic Treatment ◽

Root Canals ◽

Prevotella Nigrescens ◽

Infected Root

The objective of this clinical study was to evaluate by polymerase chain reaction (PCR) the antimicrobial efficacy and the outcome of an endodontic protocol treatment (EPT) performed by under-graduated dental students on infected root canals associated with periapical lesions. Fifty-six patients attending for treatment of pulp necrosis and apical periodontitis were included. A specific EPT approach was performed and DNA extracts were taken at the baseline (S1), after a disinfection-neutralization procedure (S2), post-chemomechanical preparation (S3) and after Intracanal medication (S4) for the presence of specific bacteria. The outcome of the EPT was assessed radiographically using the Periapical Index-system (PAI) after 18-month follow-up. An intergroup evaluation shows that when comparing S1 to S3, S1 to S4, S2 to S3, and S2 to S4, the presence of bacteria were significantly reduced (P < 0.05). Finally, S4 was not significantly reduced when compared with S3 (P > 0.05). The most prevalent species in their respect order were Actinomyces Israelii > Enterococcus Faecalis > Fusobacterium Nucleatum/Prevotella Nigrescens > Phorphyromonas Endodontalis. After the 18-month follow-up, the overall success rate of root canal – treated teeth was of 88% (PAI 1 or 2). This In Vivo study demonstrated that EPT significantly reduced the number of cases with positive results for the studied bacteria, showing a profound positive impact in the outcome of endodontic treatment of teeth diagnosed with Pulp Necrosis and Apical Periodontitis.

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Hemostasis in Infertile Patients Participating in Assisted Reproduction Programmes

Doctor Ru ◽

10.31550/1727-2378-2021-20-6-6-11 ◽

2021 ◽

Vol 20 (6) ◽

pp. 6-11

Author(s):

A.O. Godzoeva ◽

◽

I.E. Zazerskaya ◽

V.S. Vlasov ◽

T.V. Vavilova ◽

...

Keyword(s):

Reproductive Technologies ◽

Control Group ◽

Study Group ◽

Study Objective ◽

Hemostasis System ◽

Fibrin Monomer ◽

Study Results ◽

Venous Thromboembolic Events ◽

The Impact ◽

Infertile Patients

Study Objective: To evaluate the impact of multifollicular ovarian stimulation in in vitro fertilisation (IVF) programmes on hemostasis. Study Design: perspective comparative study. Materials and Methods. The study included 68 patients divided into two groups: study group (n = 36) — infertile patients; control group (n = 32) — healthy non-pregnant women of reproductive age. The protocol with gonadotrophin releasing hormone antagonists was used for ovulation stimulation. Hemostasis system in study patients was evaluated in 2 weeks after embryos were transferred to uterus; in control group — on day 20–22 of menstrual period. For the study group, we evaluated clotting test parameters of hemostasis system, D-dimers (D-d) and fibrin monomer (FM). Study Results. We have not found statistically significant differences between hemostasis screening results of study groups. We have identified increase in pro-coagulatory properties of blood in the study group patients: increase in FM and D-d (р < 0.0001 in both cases). There is an association between study parameters and pregnancy (p < 0.001) and no association with obesity, age and infertility. Conclusion. In IVF programme, FM and D-d levels rise, evidencing hypercoagulation development. An increase in FM levels was even more significant and can be used as an early and specific fibrogenesis marker. Keywords: assisted reproductive technologies, fibrin monomer, D-dimer, hypercoagulation, venous thromboembolic events.

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The Impact of Pre-emptive Large Dose of Methylprednisolone Combined With Gabapentin on Pain Treatment and Convalescence After Total Knee Arthroplasty in Elderly. A Randomized Control Study

10.21203/rs.3.rs-149103/v1 ◽

2021 ◽

Author(s):

Henryk Liszka ◽

Małgorzata Zając ◽

Artur Gądek

Keyword(s):

Total Knee Arthroplasty ◽

Single Dose ◽

Knee Arthroplasty ◽

Opioid Analgesic ◽

Control Group ◽

Study Group ◽

Intensity Level ◽

Old Patients ◽

Total Knee ◽

The Impact

Abstract Background The aim of the study was to assess whether administration of gabapentin and methylprednisolone as “pre-emptive analgesia” in a group of patients above 65 years of age would be effective in complex pain management therapy following total knee arthroplasty (TKA). Material and Methods One hundred seventy, above 65 years old patients were qualified for the study, and 10 patients were excluded due to clinical situation. One hundred sixty patients were double-blind randomized into two groups: the study (eighty patients) and controls (eighty patients). The study group received as “pre-emptive” analgesia a single dose of 300 mg oral gabapentin and 125 mg intravenous methylprednisolone, while the others placebo. Perioperatively, all the patients received opioid and nonopioid analgesic agents calculated for 1 kg of body weight. We measured the levels of inflammatory markers (leukocytosis, C-reactive protein - CRP), pain intensity level at rest (numerical rating scale - NRS), the life parameters and all complications. Results Following administration of gabapentin and methylprednisolone as “pre-emptive” analgesia CRP values being lower on all postoperative days ( 1, 2 days - p<0,00001, 3 day – p=000538), leukocytosis on day 2 (p<0,0086) and 3 (p<0,00042), the NRS score at rest 6, 12 (p<0,000001), 18 (p<0,00004) and 24 (p=0,005569) hours postoperatively . Methylprednisolone with gabapentin significantly decreased the dose of parenteral opioid preparations (p=0,000006). The duration time of analgesia was significantly longer in study group (p<0,000001). No infectious complications were observed; in the control group, one patient manifested transient ischaemic attack (TIA). Conclusion The use of gabapentin and methylprednisolone at a single dose decreases the level of postoperative pain on the day of surgery, the dose of opioid analgesic preparations, the level of inflammatory parameters without infectious processes.

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Impact of the Clinical Pharmacist on Readmission in Patients with Acute Coronary Syndrome

Annals of Pharmacotherapy ◽

10.1345/aph.1e640 ◽

2005 ◽

Vol 39 (9) ◽

pp. 1423-1427 ◽

Cited By ~ 32

Author(s):

Kate M O'Del ◽

Suzan N Kucukarslan

Keyword(s):

Unstable Angina ◽

Clinical Pharmacist ◽

Positive Impact ◽

Patient Care Team ◽

Direct Patient Care ◽

Control Group ◽

Study Group ◽

Coronary Syndrome ◽

Coronary Syndromes ◽

The Impact

BACKGROUND: Previous studies have reported a positive impact of pharmacists on care of patients with chronic illnesses. The impact of the clinical pharmacist on hospital readmission in patients with acute coronary syndromes (ACS) has yet to be evaluated, as of this writing. OBJECTIVE: To evaluate the impact of the clinical pharmacist as a direct patient-care team member on cardiac-related readmission in patients admitted to the general cardiology unit with ACS. METHODS: A prospective, nonrandomized observational study compared patients who received standard practice care with patients admitted to a service with a clinical pharmacist to provide care at the bedside. Patients admitted to and discharged from the general cardiology unit for ACS were included. The primary endpoint of the study was cardiac-related readmission at 30 days following hospital discharge. Secondary endpoints included length of stay and medication utilization. Interventions provided by the clinical pharmacist in the study group were documented. RESULTS: Cardiac readmission at 30 days was similar between the groups (p = 0.59%). In the subset of patients with unstable angina, readmission in the study group was significantly lower than in the control group (1.3% vs 9.1%; p = 0.04%). Patients in both groups were similarly managed using drug therapy and invasive coronary interventions. The medical staff's rate of acceptance of recommendations provided by the pharmacist was 94.4%. The most common interventions were medication education and identification of indicated therapy. CONCLUSIONS: The addition of pharmacists did not decrease readmission in patients with ACS. The finding of significant reduction in readmission in the subset of patients with unstable angina should be considered “hypothesis generating” for future randomized studies to confirm the results.

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Anthropometric Assessment after Slow Breathing Exercise in Type 2 Diabetic Male Patients

International Journal of Diabetes & Metabolic Disorders ◽

10.33140/ijdmd.05.02.03 ◽

2020 ◽

Vol 5 (2) ◽

Keyword(s):

Statistical Significance ◽

Control Group ◽

Study Group ◽

Physical And Mental Health ◽

Anthropometric Parameters ◽

Breathing Exercise ◽

Male Patients ◽

Slow Breathing ◽

The Impact

Background: Yoga based slow breathing exercise (SBE) has several beneficial effects on physical and mental health. Objectives: To observe the impact of slow breathing exercise on anthropometric parameters in male patients with type 2 diabetes mellitus (T2DM). Methods: This prospective interventional study was conducted on sixty (60) male diagnosed T2DM patients aged 45-55 years with duration of disease 5-10 years enrolled from Out Patients Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, and Dhaka. By simple random technique the subjects were divided into control group (n=30) and study group (n=30). Yoga based slow breathing exercise was practiced by the study group for 30 minutes twice daily for 3 months. Height, weight, body mass index (BMI), waist circumference, hip circumference and waist/hip ratio were assessed at the start of the study and after 3 months. Independent sample and paired t-test were used for statistical analysis and p<0.05was considered as statistical significance. Results: In this study the value of mean BMI was significantly (p=<0.05) reduced after 3 months of SBE. Again, all the anthropometric parameters were significantly (p=>0.05) increased after 3 months in the group who did not undergo SBE. Conclusion: Anthropometric parameters were improved after slow breathing exercise for 3 months.

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