scholarly journals ANGIOPULMONOGRAPHY WITH NITROGLYCERIN TEST IN THE DIAGNOSIS OF ACUTE INFECTIOUS LUNG DESTRUCTION

2021 ◽  
Vol 29 (4) ◽  
pp. 412-419
Author(s):  
V.I. Petukhov ◽  
◽  
V.I. Derkach ◽  
S.N. Ermashkevich ◽  
M.V. Kuntsevich ◽  
...  
Keyword(s):  
Blood Flow ◽  
Differential Diagnosis ◽  
Test Performance ◽  
Blood Circulation ◽  
Lung Parenchyma ◽  
Inflammatory Infiltration ◽  
Affected Area ◽  
Vascular Bed ◽  
Pulmonary Parenchyma ◽  
Flow Through

Objective. To develop a method for additional and differential diagnosis of acute infectious lung destruction (AILD) based on angiopulmonography with the nitroglycerin test. Methods. Angiopulmonography with the nitroglycerin test was used in 10 patients with suppurative diseasesof thelung and pleura for additional and differential diagnosis of AILD The method was used in such situations when chest computed tomography did not allow to determine unambiguously the presence and / or prevalence of necrosis of the lung parenchyma. Results. In 3 patients with the lung abscess, a clear restriction of the decay cavity was registered with the preservation of the main blood flow and weakening of the parenchymal phase of the blood circulation along the periphery of the destructive area. During the nitroglycerin test performance there was no change in the filling of the microvascular bed with contrast along the periphery of the decay cavity, which made it possible to determine the presence of parietal sequesters. According to the results of the study, the lung gangrene was diagnosed in 6 patients. At the same time, two variants of circulatory disorders were noted: the first - with preservation of the blood flow through the main vessels and with the absence of a parenchymal phase in the lesion focus, the second - with the violation of the main blood flow. In the affected area no change in blood flow was observed after the nitroglycerin test performance. Similar results of the study indicated the development of necrosis of the pulmonary parenchyma, which was subsequently confirmed during the operations performed. In the site of inflammatory infiltration of the pulmonary parenchyma with preserved main blood flow, the depletion of the parenchymal phase of blood circulation was determined, but after the nitroglycerin test, a pronounced enrichment of the vascular architecture to the parenchymal phase in the pneumonia affecting part of the lung was noted. Conclusion. It has been established that AILD is characterized by irreversible changes in the vascular bed of the lung parenchyma in the lesion focus. Angiopulmonography with the nitroglycerin test is considered to be an additional highly informative method improving the early and differential diagnosis of AILD in difficult clinical situations. What this paper adds It has been found out that during angiopulmonography the areas of pulmonary necrosis are characterized by the absence of a vascular pattern with or without disturbance of the blood flow through the segmental arteries. At the same time, in contrast to the foci of pneumonia, the nitroglycerin test is not accompanied by an evaluation of the filling of the pulmonary vascular bed in the affected area, i.e. blood supply disorders are irreversible. Thus, based on an assessment of the nature and reversibility of the blood flow disturbances in the affected lung, it is possible to carry out differential diagnosis of the early stages of acute infectious lung destruction (AILD) and pneumonia.

Effect of muscle strength and endurance development on blood flow

1961 ◽  
Vol 16 (5) ◽  
pp. 873-877 ◽  
Author(s):  
Ellen R. Vanderhoof ◽  
Charles J. Imig ◽  
H. M. Hines
Keyword(s):  
Blood Flow ◽  
Muscle Strength ◽  
Training Program ◽  
Strength Development ◽  
Flow Response ◽  
Hand Grip ◽  
Vascular Bed ◽  
Flow Through ◽  
Test Exercise ◽  
Strength Improvement

Studies were carried out to investigate the effect of hand grip strength and/or endurance improvement on blood flow through the muscles involved. One group of subjects trained for strength development and another for endurance development throughout a 29-week period. At regular intervals blood flow was measured under resting conditions and also following three different test exercise stresses designed to test the functional capacity of the vascular bed. Subjects who participated in the strength training program made significant gains in strength but not in endurance, while those subjects who trained for endurance improved in both strength and endurance. Resting blood flow was not changed significantly as a result of either training program. Significant changes in the blood flow response to the test exercise stresses were noted; these changes were associated with endurance rather than strength improvement. Submitted on April 3, 1961

Measurement of Regional Sodium Turnover Rates and Their Application to the Estimation of Regional Blood Flow

1957 ◽  
Vol 189 (2) ◽  
pp. 269-276 ◽  
Author(s):  
Ernest L. Dobson ◽  
George F. Warner
Keyword(s):  
Blood Flow ◽  
Turnover Rate ◽  
Regional Blood Flow ◽  
Removal Rate ◽  
Subcutaneous Administration ◽  
Blood Perfusion ◽  
Turnover Rates ◽  
Epinephrine Administration ◽  
Vascular Bed ◽  
Flow Through

It has been possible to estimate the regional blood flow through quantitative analysis of the sodium wash out curve obtained by a method which involves the injection of sodium 24 into an artery and the subsequent monitoring of the region (limb) supplied by this artery with external counters. The normal resting sodium turnover rate in the human forearm was found to be 10%/min. corresponding to a blood perfusion factor of 0.040 liters of blood per liter of tissue per minute. In addition to these quantitative values this method has given qualitative information on the pattern of the vascular bed. Analysis of the manner in which the removal rate changes with time has indicated that there are regions of widely differing vascularities in the area seen by the counter. Measurements following epinephrine administration have demonstrated not only a quantitative change in flow but a qualitative one as well. The subcutaneous administration of 1 mg epinephrine caused a doubling of the average total sodium turnover rate indicating a twofold increase in blood flow. The observed changes in the shape of the clearance curves could not be explained by a simple increase in linear flow rate and therefore must have involved some change in the character of the vascular bed, i.e. the conversion of some regions of low vascularity to regions of high vascularity.

Resistance to blood flow through the vascular bed of the dog forelimb

1961 ◽  
Vol 8 (4) ◽  
pp. 533-541 ◽  
Author(s):  
Henry W. Overbeck ◽  
Joyce I. Molnar ◽  
Francis J. Haddy
Keyword(s):  
Blood Flow ◽  
Vascular Bed ◽  
Flow Through

Relationship of blood flow to pressure in the intestinal vascular bed of the dog

1962 ◽  
Vol 202 (2) ◽  
pp. 253-256 ◽  
Author(s):  
E. Clinton Texter ◽  
Steven Merrill ◽  
Melvin Schwartz ◽  
Guido Van Derstappen ◽  
Francis J. Haddy
Keyword(s):  
Blood Flow ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Vascular Bed ◽  
Local Mechanism ◽  
Small Vein ◽  
Flow Through ◽  
Renal Vascular ◽  
Relationship Of ◽  
The Relationship

The relationship of pressure in the superior mesenteric artery, mesenteric small artery, mesenteric small vein, and portal vein to the rate of blood flow in the superior mesenteric artery was studied in eight dogs. Total bed resistance to blood flow decreased as a function of flow over the range 20–60 ml/min but increased as a function of flow over the range 90–270 ml/min. The onset and cessation of the resistance increase were associated with pressures in the superior mesenteric artery of 64 and 205 mm Hg, respectively. These resistance changes resulted mainly from change of resistance to flow through vessels less than 0.5 mm diameter. The findings suggest that the intestinal vascular bed, like the renal vascular bed, has a local mechanism which antagonizes changes of flow rate produced by variation of arterial pressure.

Bestimmung des zerebralen Blutflusses mittels des 81 Rb/81 mKr-Generatorsystems

1990 ◽  
Vol 29 (01) ◽  
pp. 7-12 ◽  
Author(s):  
J. Bialy ◽  
F.-J. Hans ◽  
E. Oberhausen ◽  
W.J. Peters ◽  
M. Schmitt ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Blood Circulation ◽  
Semiconductor Device ◽  
Animal Experiments ◽  
Initial Value ◽  
Brain Arteries ◽  
Sufficient Concentration ◽  
Static Quantity

A method is being developed which not only measures cerebral blood flow as a static quantity but also its changes with time. For that purpose a semiconductor device ascertains the proportion of intracerebral81 Rb and 81mKr activities. By opening the haemato-encephalic barrier in animal experiments a sufficient concentration of intracerebral81 Rb could be attained and the modified blood circulation after step-wise ligature of all brain arteries brought into relation to the corresponding Rb/Kr quotient. Over the range from undisturbed to completely interrupted cerebral blood flow this quotient varied up to 25% of its initial value.

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