scholarly journals Cytoarchitectonics of the Superior Parietal Cortex of an Outstanding Russian Scientist-Physiologist

2021 ◽  
Vol 10 (3) ◽  
pp. 9-14
Author(s):  
P. A. Agapov ◽  
I. N. Bogolepova
Keyword(s):  
Cognitive Activity ◽  
Brain Slices ◽  
Control Group ◽  
Parietal Region ◽  
Age Related ◽  
Area 7 ◽  
Cortex Area ◽  
The Brain ◽  
Satellite Glia ◽  
Profile Field

The aim of the study is to identify possible cytoarchitectonic features of the structure of the cortex in the superior parietal region of an outstanding and talented scientist-physiologist.Material and methods. The cortex (area 7) of the superior parietal region of a scientist-physiologist and men of the senile age in the control group (8 hemispheres) was studied on the series of frontal brain slices, 20 μ thick, stained with cresyl purple according to Nissl method. The cortex area thickness, the thickness of the cytoarchitectonics layer III, the area of profile field of pyramidal neurons in layers III and V, the density of neurons surrounded by satellite glia and satellite glia density in layers III and V were measured in the cortex (area 7) of the superior parietal region in the left and right hemispheres of the brain.Results. We have identified several features of the cytoarchitectonics structure of the cortex (area 7) in the brain of the scientist-physiologist that may correlate with his outstanding scientific abilities. The cortex of a scientist-physiologist is characterized by a large thickness of the studied cortex and its cytoarchitectonic layers III and V, and a greater value of the area of the profile field of neurons if compared with the cortex in men of the senile age from the control group. A higher value of the neuron density and satellite glia in the cortex of the superior parietal region of the scientist-physiologist was revealed. There was also a lower severity of age-related changes in the cortex of the scientist-physiologist compared with the control group of men.Conclusion. The structure of the cortex (area 7) of the superior parietal region of the scientistphysiologist is characterized by a greater parameter of the cortical thickness and the thickness of the associative layer III, the size of neurons and the density of satellite glia if compared with those in men of the senile age of the control group. These features distinguish the structure of his cortex from the similar cortex of the control group of men and may be related to the features of the cognitive activity of the outstanding scientist-physiologist.

scholarly journals Analysis of electrogenesis’ changes in mental retardation persons by using computer electroencephalography

2021 ◽  
Vol 11 (11) ◽  
pp. 249-265
Author(s):  
B. Lobasyuk ◽  
L. Bartsevich ◽  
A. Zamkovaya
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mental Retardation ◽  
Theta Rhythm ◽  
Cognitive Activity ◽  
Control Group ◽  
Bioelectrical Activity ◽  
The Central Nervous System ◽  
Beta Rhythms ◽  
The Brain

Justification. Mental retardation is a persistent decrease in human cognitive activity against the background of organic damage to the central nervous system. Neurophysiological diagnostics, in particular electroencephalography (EEG), most adequately reflects the morpho-functional state of the central nervous system, which is the basis of the mechanisms of mental activity, and the originality of the bioelectrical activity of the brain can be considered as the main indicator that determines a decrease in the level of intellectual development and, thereby, characterizes this state. This provision actualizes the search for highly informative indicators of the originality of the bioelectrical activity of the brain in children with intellectual disabilities. Purspose. With the use of periodometric analysis investigate EEG’s indicators and interhemispheric asymmetry of rhythms amplitudes in MR patients. Materials and methods. The EEG was recorded in a state of calm wakefulness with closed eyes with Neuron-Spectrum-2 electroencephalograph. Differences in indicators were tracked using the calculation of the coefficient of compliance (CC), EEG functional asymmetry coefficients in amplitude were determined, too. Results. It was revealed that in MR patients the amplitudes of the rhythms were greater than in healthy subjects. The greatest increase was determined in theta rhythm in the anterior temporal and posterior temporal leads in the left hemispheres. Duration indices in the delta, theta and alpha ranges of the EEG in mental retardation compared with the control group were increased, and the indices of the duration of beta rhythms - decreased. When analyzing FMPA in MR persons it turned out that in right-handers the negativeness of FMPA indices increased, and in left-handers there was an increase in the positivity of FMPA indices. Conclusions 1. With mental retardation, the amplitudes of the rhythms were greater than in healthy people. The greatest increase was determined in theta rhythm in the anterior temporal and posterior temporal leads in the left hemispheres. 2. The indices of duration in the delta, theta and alpha ranges of the EEG of MR subjects were increased, and the indices of the duration of beta rhythms – decreased. 3. When analyzing FMPA in MR persons, it turned out that in right-handers the negativeness of FMPA indices increased, and in left-handers there was an increase in the positivity of FMPA indices.

Psychological peculiarities of auditory cognitive defect when psychopathology

2014 ◽  
Vol 5 (1) ◽  
pp. 37-43
Author(s):  
Kseniya Alekseyevna Belskaya ◽  
Sergey Aleksandrovich Lytayev ◽  
Nikita Yuryevich Kipyatkov
Keyword(s):  
Latent Period ◽  
Functional State ◽  
Paranoid Schizophrenia ◽  
Cognitive Activity ◽  
Original Method ◽  
Control Group ◽  
Time Interval ◽  
Auditory Analyzer ◽  
The Status ◽  
The Brain

Work is executed on faculty of normal physiology of Saint-Petersburg state pediatric medical University of the Ministry of health of Russia and St. Petersburg psycho-neurological dispensary N 1. Of the existing Arsenal of psychophysiological methods in this study, we used the original method of studying perception of auditory images and psychological analysis of the status of higher mental functions in patients suffering from paranoid schizophrenia and control group. With increasing levels of anxiety, both healthy subjects and in patients of any information provided may be assessed as important. In such circumstances, the inhibition processes touch flow reduced and insignificant background is estimated sick longer than healthy. Normal perception clean and noisy auditory images has high identifiability (95 %) and efficiency with latent period of 4.2-8.4 C. Taking into account time for вербализацию a decision and biologically significant effect on the perceived information, this time interval corresponds to the physiological norm. The effectiveness of the perception of auditory images in chronic psychopathology is within 40- 75 %, and the latent period - within 11.2-24.3 with that 2.6-2.9 times exceeds the normative time of identification. Reduction in speed and efficiency of information-analytical activities in psychopathological disorders caused, apparently, by the decrease of the functional state of stem-reticular structures included in the first structural-functional Department of the auditory analyzer. The dependence of the quality of auditory-cognitive activity not only from the functional state of cortical fields, responsible for attention, perception, recognition, remembering, but also on the state of slightly-stem systems of the brain responsible tone and reactivity of the brain. Registered reliable link of functional reduce nonspecific brain systems in violation of the neurophysiological mechanisms of perception.

scholarly journals Task-Induced Functional Connectivity of Picture Naming in Healthy Aging: The Impacts of Age and Task Complexity

2020 ◽  
Vol 1 (2) ◽  
pp. 161-184
Author(s):  
Perrine Ferré ◽  
Julien Jarret ◽  
Simona Maria Brambati ◽  
Pierre Bellec ◽  
Yves Joanette
Keyword(s):  
Functional Connectivity ◽  
Picture Naming ◽  
Healthy Aging ◽  
Cognitive Activity ◽  
Naming Task ◽  
Word Production ◽  
Task Demand ◽  
Age Related ◽  
The Brain ◽  
And Task

The topological organization of the brain, governed by the capacity of brain regions to synchronize their activity, allows for cost-effective performance during everyday cognitive activity. Functional connectivity is an fMRI method deemed task-specific and demand-dependent. Although the brain undergoes significant changes during healthy aging, conceptual knowledge and word-production accuracy are generally preserved. The exploration of task-induced functional connectivity patterns during active picture naming may thus provide additional information about healthy functional cerebral mechanisms that are specifically adapted to the cognitive activity at hand. The goal of this study is to assess and describe age-related differences in functional connectivity during an overt picture-naming task, as well as to compare age-related differences under complex task demand, defined by lexical frequency. Results suggest both age-specific and task-specific mechanisms. In the context of preserved behavioral performance in a picture-naming task, older adults show a complex array of differences in functional connectivity architecture, including both increases and decreases. In brief, there is increased segregation and specialization of regions that are classically assigned to naming processes. Results also expand on previous word-production studies and suggest that motor regions are particularly subject to age-related differences. This study also provides the first indication that intrinsic task demand, as manipulated by lexical frequency, interacts little with the relationship between age and functional connectivity. Together, these findings confirm the value of task-induced functional connectivity analysis in revealing the brain organization that subserves task performance during healthy aging.

Psychological peculiarities of auditory cognitive defect when psychopathology

2014 ◽  
Vol 5 (2) ◽  
pp. 88-94
Author(s):  
Kseniya Alekseyevna Belskaya ◽  
Sergey Aleksandrovich Lytayev ◽  
Nikita Yuryevich Kipyatkov
Keyword(s):  
Latent Period ◽  
Functional State ◽  
Paranoid Schizophrenia ◽  
Cognitive Activity ◽  
Original Method ◽  
Control Group ◽  
Time Interval ◽  
Auditory Analyzer ◽  
The Status ◽  
The Brain

Work is executed on faculty of normal physiology of Saint-Petersburg state pediatric medical University of the Ministry of health of Russia and St. Petersburg psycho-neurological dispensary N 1. Of the existing Arsenal of psychophysiological methods in this study, we used the original method of studying perception of auditory images and psychological analysis of the status of higher mental functions in patients suffering from paranoid schizophrenia and control group. With increasing levels of anxiety, both healthy subjects and in patients of any information provided may be assessed as important. In such circumstances, the inhibition processes touch flow reduced and insignificant background is estimated sick longer than healthy. Normal perception clean and noisy auditory images has high identifiability (95 %) and efficiency with latent period of 4.2-8.4 C. Taking into account time for вербализацию a decision and biologically significant effect on the perceived information, this time interval corresponds to the physiological norm. The effectiveness of the perception of auditory images in chronic psychopathology is within 40-75 %, and the latent period - within 11.2-24.3 with that 2.6-2.9 times exceeds the normative time of identification. Reduction in speed and efficiency of information-analytical activities in psychopathological disorders caused, apparently, by the decrease of the functional state of stem-reticular structures included in the first structural-functional Department of the auditory analyzer. The dependence of the quality of auditory-cognitive activity not only from the functional state of cortical fields, responsible for attention, perception, recognition, remembering, but also on the state of slightly-stem systems of the brain responsible tone and reactivity of the brain. Registered reliable link of functional reduce nonspecific brain systems in violation of the neurophysiological mechanisms of perception.

AGE-RELATED CHANGES OF THE PROFILE FIELD OF NEURONS OF THE AREA 7 OF THE BRAIN OF MEN AND WOMEN IN THE PROCESS OF THE AGING

2019 ◽  
Vol 27 (3) ◽  
pp. 8-15
Author(s):  
P. A. Agapov ◽  
I. N. Bogolepova ◽  
L. I. Malofeeva
Keyword(s):  
Pyramidal Neurons ◽  
Age Groups ◽  
The Elderly ◽  
Men And Women ◽  
Age Related ◽  
Female Brain ◽  
Group 5 ◽  
The Brain ◽  
Age Related Changes ◽  
Profile Field

The aim of the work is to study changes in the profile field of pyramidal neurons in the cortex of field 7 of the brain of men and women in the aging process. A cytoarchitectonic study of the cortex of field 7 of the upper parietal region of the brain of men and women was carried out on a series of frontal paraffin sections stained by the Nissl method. The brain preparations of men and women of three age groups were studied: the groups of mature age (from 20 to 60 years), the elderly group (from 60 to 75 years) and the group of senile age (from 75 years and older). In each age group, 5 preparations of the male brain and 5 preparations of the female brain were studied. Age-related changes in the cytoarchitectonics of the profile field of pyramidal neurons in the cytoarchitectonic layers of the third and fifth cortex fields 7 of the brain of men and women were studied. As a result of the study, it was revealed that in the process of aging of the brain of men and women, changes in similar morphometric indicators of field 7 cortex occur at different age periods, the dynamics of age-related changes in functionally different cytoarchitectonic layers III and V of the cerebral cortex of men and women are also different.

scholarly journals Analysis of teachers’ knowledge on the brain development and cognitive activity in children. Results of anonymous survey

2020 ◽  
pp. 97-112
Author(s):  
L.V. Sokolova ◽  
◽  
V.A. Vasilyeva ◽  
K.V. Orlov ◽  
N.S. Shumeyko ◽  
...  
Keyword(s):  
Brain Development ◽  
Children And Adolescents ◽  
Cognitive Activity ◽  
Teaching Experience ◽  
Social Adaptation ◽  
Educational Organizations ◽  
Significant Relation ◽  
Age Related ◽  
And Behavior ◽  
The Brain

Anonymous voluntary questioning was carried out on teachers of educational organizations from 10 Russian regions. 7117 r espondents took part in the survey: kindergarten teachers of preschool educational organizations, teachers of three levels of school education. The research objective is to assess the teachers’ awareness about the basic terms and concepts associated with the functioning of the nervous system, age-related characteristics of cognitive activity and behavior of children and adolescents, problems of learning and social adaptation that may arise due to age-related features of the growing organism. The analysis of the obtained data did not reveal significant differences in the surveyed groups. There was no significant relation between teaching experience and the knowledge level. Predominance of correct answers was found among teachers of biology. The questions about the age characteristics of the cognitive activity of preschool children and adolescents were the most difficult for the respondents. The obtained results indicate the need for add itional educational programs for teachers, which will give them the opportunity to know recent concepts on the brain development and cognitive activity of a child. The data of this study could be used to develop the program and determine the content of the section "Brain development and the formation of the cognitive activity of a child" in the trai ning course "Pedagogical physiology"

Oral and Oropharyngeal Sensory Function in Adults With Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 29 (2) ◽  
pp. 864-872
Author(s):  
Fernanda Borowsky da Rosa ◽  
Adriane Schmidt Pasqualoto ◽  
Catriona M. Steele ◽  
Renata Mancopes
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Oral Cavity ◽  
Pulmonary Disease ◽  
Thermal Sensation ◽  
Sensory Function ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Age Related ◽  
Copd Patients

Introduction The oral cavity and pharynx have a rich sensory system composed of specialized receptors. The integrity of oropharyngeal sensation is thought to be fundamental for safe and efficient swallowing. Chronic obstructive pulmonary disease (COPD) patients are at risk for oropharyngeal sensory impairment due to frequent use of inhaled medications and comorbidities including gastroesophageal reflux disease. Objective This study aimed to describe and compare oral and oropharyngeal sensory function measured using noninstrumental clinical methods in adults with COPD and healthy controls. Method Participants included 27 adults (18 men, nine women) with a diagnosis of COPD and a mean age of 66.56 years ( SD = 8.68). The control group comprised 11 healthy adults (five men, six women) with a mean age of 60.09 years ( SD = 11.57). Spirometry measures confirmed reduced functional expiratory volumes (% predicted) in the COPD patients compared to the control participants. All participants completed a case history interview and underwent clinical evaluation of oral and oropharyngeal sensation by a speech-language pathologist. The sensory evaluation explored the detection of tactile and temperature stimuli delivered by cotton swab to six locations in the oral cavity and two in the oropharynx as well as identification of the taste of stimuli administered in 5-ml boluses to the mouth. Analyses explored the frequencies of accurate responses regarding stimulus location, temperature and taste between groups, and between age groups (“≤ 65 years” and “> 65 years”) within the COPD cohort. Results We found significantly higher frequencies of reported use of inhaled medications ( p < .001) and xerostomia ( p = .003) in the COPD cohort. Oral cavity thermal sensation ( p = .009) was reduced in the COPD participants, and a significant age-related decline in gustatory sensation was found in the COPD group ( p = .018). Conclusion This study found that most of the measures of oral and oropharyngeal sensation remained intact in the COPD group. Oral thermal sensation was impaired in individuals with COPD, and reduced gustatory sensation was observed in the older COPD participants. Possible links between these results and the use of inhaled medication by individuals with COPD are discussed.

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