scholarly journals Miniscrew-assisted rapid palatal expander (MARPE) therapeutic results: A review

2021 ◽  
Author(s):  
Mahsa Mortazavi ◽  
Reza Sharifi ◽  
Mahboube Hasheminasab
Keyword(s):  
Systematic Review ◽  
English Language ◽  
High Efficiency ◽  
Three Dimensional ◽  
Case Series ◽  
Contributory Factor ◽  
Success Rates ◽  
Maxillary Expansion ◽  
Case Series Study ◽  
Therapeutic Results

Background: One of the most common maxillary abnormalities is transverse deficiency, which can be a contributory factor in malocclusions. There are some evidence of successful non-surgical treatment of this type of discrepancy after puberty by using maxillary expansion techniques. The Miniscrew-assisted rapid palatal expander (MARPE) method is a newly introduced method that has attracted the interest of many orthodontists. This study aimed to evaluate the therapeutic results of this technique in a systematic review. Method: In this study, various databases including PubMed, Scopus, and ISI (Web of science) were queried with proper keywords, provided by PICO strategy of research, from 1980 to December 2020. Relevant articles were collected with restrictions on the English language. The full text of papers with all inclusion criteria was assessed.  The therapeutic outcomes of MARPE were evaluated in the selected studies. Results: A total of 14 studies were included in the systematic review. Totally, 5 case report studies, 8 retrospective studies, and 1 case series study were reviewed. Cone-beam computed tomography was used as an outcome measure in all studies. In all reviewed studies, maxillary expansion occurred with high success rates in patients. Moreover, respiratory characteristics were also assessed in two studies measuring respiratory muscle strength, airflow and nasal and nasopharyngeal airway volume, showing benefits of MARPE. A study also examined three-dimensional soft tissue stereophotogrammetry. Based on these studies, the indication for using this method was a maxillary transverse deficiency as well as upper and lower arches crowding. No serious complications were reported in any of the reviewed studies. However, most studies did not perform long-term follow-ups and the age range of the subjects was mainly between 12 and 24 years. MARPE has been suggested as a treatment modality for correction of maxillary transverse deficiency in young adults but patients under the age of 14 may also benefit from this treatment in special conditions. Conclusion: A general review of the results of studies showed the high efficiency of MARPE technique in correcting maxillary transverse deficiency.

Design and fabrication of anisotropic textile brace for exerting corrective forces on spinal curvature

2021 ◽  
pp. 152808372110326
Author(s):  
Queenie Fok ◽  
Joanne Yip ◽  
Kit-lun Yick ◽  
Sun-pui Ng
Keyword(s):  
Medical Condition ◽  
Three Dimensional ◽  
Case Series ◽  
The Body ◽  
Spinal Curvature ◽  
Radiographic Examination ◽  
Interface Pressure ◽  
Pressure System ◽  
Case Series Study ◽  
Point Pressure

This study focuses on the fabrication of an anisotropic textile brace that exerts corrective forces based on the three-point pressure system to treat scoliosis, which is a medical condition that involves deformity of the spine. The design and material properties of the proposed anisotropic textile brace are discussed in detail here. A case series study with 5 scoliosis patients has been conducted to investigate the immediate in-brace effect and biomechanics of the proposed brace. Radiographic examination, three-dimensional scanning of the body and interface pressure measurements have been used to evaluate the immediate effect of the proposed brace on reducing the spinal curvature and asymmetry of the body contours and its biomechanics. The results show that the proposed brace on average reduces the spinal curvature by 11.7° and also increases the symmetry of the posterior trunk by 14.1% to 43.2%. The interface pressure at the corrective pad ranges from 6.0 to 24.4 kPa. The measured interface pressure shows that a sufficient amount of pressure has been exerted and a three-point pressure distribution is realized to reduce the spinal curvature. The obtained results indicate the effectiveness of this new approach which uses elastic textile material and a hinged artificial backbone to correct spinal deformity.

scholarly journals Hunger strikes in prisons: a narrative systematic review of ethical considerations from a physician’s perspective

2017 ◽  
Vol 35 (2) ◽  
pp. 135-142 ◽  
Author(s):  
G. Gulati ◽  
B. D. Kelly ◽  
D. Meagher ◽  
H. Kennedy ◽  
C. P. Dunne
Keyword(s):  
Systematic Review ◽  
English Language ◽  
Case Series ◽  
Database Search ◽  
World Medical Association ◽  
Hunger Strike ◽  
Ethical Considerations ◽  
Dual Loyalty ◽  
The World ◽  
Physician’S Perspective

ObjectivesWe sought to identify and review published studies that discuss the ethical considerations, from a physician’s perspective, of managing a hunger strike in a prison setting.MethodsA database search was conducted to identify relevant publications. We included case studies, case series, guidelines and review articles published over a 20-year period. Non-English language publications were translated.ResultsThe review found 23 papers from 12 jurisdictions published in five languages suitable for inclusion.ConclusionsKey themes from included publications are identified and summarised in the context of accepted guidelines from the World Medical Association. Whilst there seems to be an overall consensus favouring autonomy over beneficence, tensions along this fine balance are magnified in jurisdictions where legislation leads to a dual loyalty conflict for the physician.

Thrombolytic Salvage of the Frostbitten Upper Extremity: A Systematic Review

Hand ◽  
2020 ◽  
pp. 155894472094006
Author(s):  
James Drinane ◽  
Adee J. Heiman ◽  
Joseph A. Ricci ◽  
Ashit Patel
Keyword(s):  
Systematic Review ◽  
Thrombolytic Therapy ◽  
Upper Extremity ◽  
Animal Studies ◽  
English Language ◽  
Case Series ◽  
Current Data ◽  
Ischemic Tissue ◽  
Promising Treatment ◽  
Salvage Rate

Background Vascular thrombosis secondary to frostbite can lead to ischemic tissue damage in severe cases. Threatened extremities may be salvaged with thrombolytics to restore perfusion; however, current data are limited to single institution case series. The authors performed a systematic review to determine the efficacy of thrombolytic therapy in treating upper extremity frostbite. Methods PubMed, EBSCO, and Google Scholar were queried using the keywords “thrombolytics,” “frostbite,” “fibrinolytics,” and “tPA.” Exclusion criteria were failure to delineate anatomic parts injured, failure to report number of limbs salvaged, animal studies, and non-English language publications. Thrombolytic therapy was defined as intraarterial (IA) or intravenous (IV) administration of tissue plasminogen activator (tPA), alteplase, urokinase, streptokinase, or any tPA derivative. Results A total of 42 studies were identified, with 13 satisfying inclusion criteria. Eight studies reported catheter-directed IA thrombolysis, four reported systemic IV administration, and 1 reported both methods. A total of 157 patients received thrombolytics. In all, 73 upper extremity digits were treated by IA route and 136 digits were treated by IV route. Overall upper extremity digit salvage rate was 59%. There was a significantly higher salvage rate in digits treated by the IA route compared to the IV route. Conclusions Thrombolytics, particularly when administered by the intra-arterial route, are emerging as a promising treatment of severe frostbite of the upper extremity, increasing digit salvage rates.

scholarly journals 119. Nocardia Bacteremia Is Almost Always Associated with Immune Compromise or an Intravascular Device: Single-Center Case Series and Systematic Review of the Literature

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S90-S90
Author(s):  
Eloise Williams ◽  
Adam W Jenney ◽  
Denis W Spelman
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
Systematic Literature Review ◽  
English Language ◽  
Case Series ◽  
Blood Cultures ◽  
Single Center ◽  
Intravascular Device ◽  
Pubmed Database ◽  
All Cause Mortality

Abstract Background Nocardia bacteremia is a rare but important phenomenon, with previous studies describing a 50% mortality rate. We undertake a single-center review and the largest systematic review of Nocardia bacteremia performed over the past 20 years. Methods A single-center review of cases of Nocardia bacteremia was performed using hospital microbiology records from January 1, 2010 to December 31, 2017. A systematic literature review was also performed to identify cases of Nocardia bacteremia described in the English language literature between January 1, 1999 and December 31, 2018 using the NCBI PubMed database and snowballing from citations of relevant publications. Results Single-center case series: Four cases of Nocardia bacteremia are described. Three patients had an intravascular device in situ prior to the onset of Nocardia bacteremia and three patients were immunocompromised; one patient had both risk factors. Systematic literature review: A systematic review identified 50 publications that described 85 cases with sufficient patient data to be reviewed in detail. Including the 4 cases described in our institution, 89 cases of Nocardia bacteremia were included in the analysis. The median age was 57 years [interquartile range (IQR) 42–68] and 69% were male. Eighty-two percent of cases were immunocompromised and 38% had endovascular devices. Pulmonary infection was the most common concurrent site of clinical disease (66%), followed by central nervous system (25%), pleural (17%) disease, and endocarditis (11%). Blood cultures were the only positive microbiological specimen that isolated Nocardia in 45% of cases. Median incubation time to blood culture positivity was 4 days [IQR 3–6]. Thirty-day all-cause mortality was 24% and overall all-cause mortality was 42%. Conclusion Four new cases of Nocardia bacteremia are described. Isolation of Nocardia from blood cultures is rare but represents serious infection with high associated overall mortality. Nocardia bacteremia is most frequently identified in immunocompromised patients and those with intravascular devices. Disclosures All authors: No reported disclosures.

Electrochemotherapy of Cutaneous Metastases of Melanoma-A Case Series Study and Systematic Review of the Evidence

2011 ◽  
Vol 37 (6) ◽  
pp. 816-824 ◽  
Author(s):  
ERIKA KIS ◽  
JUDIT OLÁH ◽  
HENRIETTE ÓCSAI ◽  
ESZTER BALTAS ◽  
ROLLAND GYULAI ◽  
...  
Keyword(s):  
Systematic Review ◽  
Case Series ◽  
Cutaneous Metastases ◽  
Case Series Study ◽  
Series Study

scholarly journals Efficacy of treatment interventions for primary aneurysmal bone cysts: a systematic review

2021 ◽  
Vol 2 (2) ◽  
pp. 125-133
Author(s):  
Luckshman Bavan ◽  
Asanka Wijendra ◽  
Alpesh Kothari
Keyword(s):  
Systematic Review ◽  
Case Series ◽  
Injection Therapy ◽  
Long Bones ◽  
Bone Cysts ◽  
Success Rates ◽  
Eligibility Criteria ◽  
Treatment Groups ◽  
Aneurysmal Bone Cysts ◽  
Quality Evidence

Aims Aneurysmal bone cysts (ABCs) are locally aggressive lesions typically found in the long bones of children and adolescents. A variety of management strategies have been reported to be effective in the treatment of these lesions. The purpose of this review was to assess the effectiveness of current strategies for the management of primary ABCs of the long bones. Methods A systematic review of the published literature was performed to identify all articles relating to the management of primary ABCs. Studies required a minimum 12-month follow-up and case series reporting on under ten participants were not included. Results A total of 28 articles meeting the eligibility criteria were included in this review, and all but one were retrospective in design. Due to heterogeneity in study design, treatment, and outcome reporting, data synthesis and group comparison was not possible. The most common treatment option reported on was surgical curettage with or without a form of adjuvant therapy, followed by injection-based therapies. Of the 594 patients treated with curettage across 17 studies, 86 (14.4%) failed to heal or experienced a recurrence. Similar outcomes were reported for 57 (14.70%) of the 387 patients treated with injection therapy across 12 studies. Only one study directly compared curettage with injection therapy (polidocanol), randomizing 94 patients into both treatment groups. This study was at risk of bias and provided low-quality evidence of a lack of difference between the two interventions, reporting success rates of 93.3% and 84.8% for injection and surgical treatment groups, respectively. Conclusion While both surgery and sclerotherapy are widely implemented for treatment of ABCs, there is currently no good quality evidence to support the use of one option over the other. There is a need for prospective multicentre randomized controlled trials (RCTs) on interventions for the treatment of ABCs. Cite this article: Bone Jt Open 2021;2(2):125–133.

scholarly journals The microbiological and physical properties of catheters for intermittent catheterization: A systematic review on the impact of reuse and cleaning methods

2021 ◽  
Author(s):  
Mark Grasdal ◽  
Matthias Walter ◽  
Andrei V. Krassioukov
Keyword(s):  
Systematic Review ◽  
Physical Properties ◽  
Bacterial Colonization ◽  
Case Series ◽  
Intermittent Catheterization ◽  
Cochrane Central Register ◽  
Cross Sectional ◽  
Case Series Study ◽  
Cleaning Methods ◽  
The Impact

AbstractThis systematic review provides an up to date and comprehensive summary of the clinical evidence of the effectiveness of various cleaning methods of intermittent catheterization that have been proposed to prepare catheters for reuse. This systematic review is registered at PROSPERO (registration number: CRD42020176065). A key word search of Medline (OVID), Excerpta Medica dataBASE (EMBASE, OVID), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Web of Science and the Cochrane Central Register of Controlled Trials (CENTRAL), in addition to manual searches of retrieved articles, was undertaken to identify all English, Russian and German language literature evaluating the effectiveness of various cleaning methods of intermittent catheterization. Studies selected for review included analytical experimental, prospective cohort, cross-sectional and case series study designs. Prospective cleaning methods analyzed included heat-based sterilization, chemical cleaning solutions, mechanical abrasion, photocatalytic sterilization, and combined methods. Studies that failed to assess the bacterial colonization or physical properties of catheters following cleaning were excluded. In total, 12 studies (i.e. 9 analytical experimental, 1 cohort study, 1 cross-sectional and 1 case series) were included. Two cleaning methods were identified as likely being most promising: five-minute submersion in 70% alcohol and the “Milton method”. Each eliminated bacterial colonization without affecting the physical properties of the catheters. All other cleaning methods were either non-bactericidal or caused gross visual or microscopic damage to the catheters, rendering their reuse unsafe. Additional higher-powered studies confirming the safety and efficacy of these cleaning methods must be obtained before we would feel comfortable challenging current clinical recommendations.

scholarly journals Acute Cardiac Injury and COVID-19 – A Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Husam M Salah ◽  
Angel Lopez Candales
Keyword(s):  
Systematic Review ◽  
Mortality Rate ◽  
Meta Analysis ◽  
Cardiac Injury ◽  
Case Series ◽  
Common Finding ◽  
Full Spectrum ◽  
Global Pandemic ◽  
Current Prevalence ◽  
Case Series Study

Abstract Introduction:The ongoing global pandemic, coronavirus disease 2019 (COVID-19), an illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has ranged from an asymptomatic state to unprecedented number of deaths worldwide. In symptomatic patients, a viral pneumonia can unrelentingly progress to multi-system failure with preferential cardiac tropism. Although the full spectrum of COVID-19 cardiac manifestations is still not clear; acute cardiac injury (ACI) remains a common finding. The goal of our study, not only is to examine the current prevalence of ACI among COVID-19 infected patients but also, the reported mortality.Method:After thoroughly searching the literature for appropriate studies, a systematic review and meta-analysis were performed. Inclusion criteria were 1) Cohort study, case-control study, or case series study. 2) The study population included individuals with COVID-19 3) The presence or absence of cardiac injury was reported in the study 4) Mortality among patients with cardiac injury is reported or can be calculated.Results:Ten studies were included with a total of 1664 patients. The prevalence of ACI was 30.8%. The mortality rate among patients with concurrent COVID-19 and ACI was 53%.Conclusion:ACI can occur in one third of patients with COVID-19. Concurrent COVID-19 and ACI entails a high mortality rate. Serum troponin level can be a good prognostic tool in COVID-19.

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