Experience with dexmedetomidine for sedanalgesia during rhinosurgery

2021 ◽  
Vol 20 (3) ◽  
pp. 102-107
Author(s):  
E. S. Grigor’kina ◽  
◽  
N. M. Vingovatova ◽  
N. G. Emelina ◽  
V. G. Nedovarov ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pain Relief ◽  
Local Anesthetic ◽  
Postoperative Period ◽  
Optimal Level ◽  
Control Group ◽  
Hemodynamic Parameters ◽  
Pain Level ◽  
Respiratory Parameters ◽  
Endotracheal Anesthesia

The aim of this work was to study the possibility of rhinosurgical interventions using the drug dexmedetomidine for controlled sedoanalgesia. Materials and methods: 118 rhinological interventions (polysinusotomy, pansinusotomy, septoplasty) were performed under combined sedation: 56 with dexmedetomidine and 62 with sibazone. Intraoperatively, the amount of narcotic analgesic and local anesthetic, pain level and depth of sedation, hemodynamic and respiratory parameters, bleeding intensity and operating visibility were considered; in the postoperative period - the level of pain, bleeding when removing tampons from the nose, satisfaction of the surgeon and the patient. Results: during sedanalgesia with dexmedetomidine, the optimal level of sedation was achieved, the amount of narcotic and local anesthetic was reduced, hemodynamic parameters were comfortable for the surgeon (lower than in the control group, blood pressure), which, first of all, provided good operational visibility. In the postoperative period, there was a higher satisfaction of the patient and the surgeon with the performed anesthetic aid. Conclusions: sedoanalgesia with the drug dexmedetomidine can be used in uncomplicated cases during rhinosurgical interventions as an alternative to endotracheal anesthesia, providing optimal pain relief and comfortable work of the surgeon.

scholarly journals MAIN INDIVIDUAL AND TYPOLOGICAL PARAMETERS OF HIGHER NERVOUS ACTIVITY IN YOUNG PEOPLE OF DIFFERENT SOMATOTYPE WITH NORMAL AND HIGH BLOOD PRESSURE

2020 ◽  
Vol 5 (2) ◽  
pp. 47-55
Author(s):  
S. N. Vadzyuk ◽  
L. I. Horban ◽  
I. Ya. Papinko
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Nervous Activity ◽  
Circulatory System ◽  
Optimal Level ◽  
Functional Mobility ◽  
Control Group ◽  
Higher Nervous Activity ◽  
The Central Nervous System ◽  
The Individual

Background. The individual and typological features of the central nervous system are interpreted as highly genetically determined. Each somatotype is characterized by morphofunctional features of the activity of different systems, including the circulatory system. Objective. The aim of the research was to study the features of the main individual and typological parameters of higher nervous activity in persons of different somatotype with normal and high blood pressure (BP). Methods. In the control group of the surveyed patients the BP value corresponded to the optimal level according to the WHO classification (125 people). The second group consisted of individuals, whose systolic blood pressure exceeded 130 mmHg at the time of the study and (or) diastolic – 85 mmHg (135 people). Somatotyping technique by Carter and Heath was used. Functional mobility (FMNP) and strength of nervous processes (SNP) were determined using the Diagnost-1 program (Makarenko and Lizogub). Results. In the individuals with predominance of ecto- and mesomorphic somatotype component, higher levels of major nervous processes were reported in response to strenuous processing of information, which was associated with more advanced mechanisms of information processing, its neurophysiological support. In people with endomorphic somatotype the lower levels of FMNP and SNP were clearly detected that could indicate that the speed characteristics of the nervous processes in them are at a lower level. Conclusions. In normal blood pressure, the highest indicator of FMNP was found in the individuals with predominance of ecto- and mesomorphic component. In the group with high blood pressure, the indicator at the level below the average was in endomorphs. Predominance of the ectomorphic component tended to increase in the surveyed, and in the mesomorphs was at the average level. The lowest level of SNP was found in the individuals with endomorphic somatotype of both groups.

scholarly journals RESULTS OF ENDOSCOPIC DIAGNOSIS OF BLEEDING AFTER ABDOMINAL SURGICAL OPERATIONS

2021 ◽  
Vol 21 (3) ◽  
pp. 129-134
Author(s):  
I. A. Yusubov ◽  
N. A. Gasimov ◽  
E. Y. Sharifov
Keyword(s):  
Blood Pressure ◽  
Gastrointestinal Bleeding ◽  
Postoperative Period ◽  
Abdominal Cavity ◽  
Postoperative Bleeding ◽  
Clinical Signs ◽  
Control Group ◽  
Laboratory Findings ◽  
Abdominal Bleeding ◽  
Surgical Methods

The aim of the study is to conduct a comparative analysis of the effectiveness of endovidiosurgical diagnosis techniques to detect gastrointestinal and intra-abdominal bleeding, which may occur after abdominal operations. Materials and methods. The main group included patients (n=408), whose condition was controlled by the endovideosurgical techniques. The control group included patients (n=102) who were controlled by using conventional surgical methods to correct bleeding that may occurred after similar surgical interventions. Gastrointestinal bleeding was observed in 323 patients, and intra-abdominal bleeding was observed in 85 patients. In all cases, endoscopic haemostasis was performed by clipping (n=57), submucosal infiltration (n=32), electrocoagulation (n=29), argon-plasma coagulation (n=74), and combined techniques (n=54). Results and discussion. 408 patients with clinical signs of bleeding in the early postoperative period were examined by endoscopic techniques. Patients with alarming clinical and laboratory findings underwent ultrasound examination, which revealed the presence of free fluid in one or more parts of the abdominal cavity. Laparoscopy was performed in the first hours of the postoperative period in 17 cases (n=17); on the first day of the postoperative period (n=36), on the second day (n=19), on the third (n=8), on the fifth (n=3), and on the sixth day (n=2). Complications were excluded in 7 (16.0%) patients, despite a decrease in blood pressure and haemoglobin levels. The volume of blood found in the abdominal cavity, including clots, ranged from 30 ml to 2000 ml. Signs of ongoing bleeding (the predominance of a large amount of liquid blood with a small number of clots) were found in 49 (57.6%) cases, and signs of arrested bleeding (the presence of a large number of clots with a small amount of liquid blood) was detected in 29 (34.1%) cases. Haemostasis was provided by electrocoagulation (n=35), clipping (n=15), suturing (n=12) and tamponade from a mini-laporatomic incision (n=9). Gastrointestinal bleeding was observed in 323 patients, and intra-abdominal bleeding in 85 patients. In 8.4% (n=27) of cases, the suspicious cases of postoperative complication were excluded by endoscopic examinations. In 91.6% (n=296) of clinical cases, early postoperative bleeding or signs of unstable haemostasis with the risk of repeated bleeding were confirmed. In cases of alarming clinical and laboratory findings indicating intra-abdominal bleeding, diagnostic laparoscopy enables to exclude complications in 16.0% of patients, despite a decrease in blood pressure and haemoglobin levels.

“A COMPARATIVE STUDY TO EVALUATE THE EFFICACY OF IN POSTOPERAT ETORICOXIB IN PAIN RELIEF IN PATIENTS IN UNDERGOING LUMBAR SPINE SURGERY ”

2021 ◽  
pp. 65-66
Author(s):  
Deepti chauhan ◽  
Ashish Mathur ◽  
Sukhnandan Singh Tomar ◽  
Heena sheikh
Keyword(s):  
Blood Pressure ◽  
Lumbar Spine ◽  
Pain Relief ◽  
General Anaesthesia ◽  
Spine Surgery ◽  
Lumbar Spine Surgery ◽  
Analgesic Requirement ◽  
Placebo Tablet ◽  
Respiratory Parameters ◽  
Different Doses

AIMS AND OBJECTIVES: To evaluate the efcacy of Etoricoxib in different doses in postoperative pain relief in patients undergoing lumbar spine surgery. MATERIALAND METHOD : 80 patients of ASA grade І & ІІ of either sex scheduled for lumbar spine surgery under general anaesthesia were divided into 2 groups (n=40 each) randomly.Group E (n=40) Patients who received a 90 mg Etoricoxib 1 hour before surgery and another tablet the following morning. Group 'P'(n=40) Patients who received a placebo tablet 1 hour before surgery and again the following morning. Pulse rate, blood pressure, respiratory rate and severity of pain on NRS scale was noted at 0 hr, 4 hr, 8 hr, 12 hr, 16 hr, 20 hr, 24 hr, 28 hr, 32 hr and 48 hr after surgery. And the presence or absence of adverse effects, such as headache, nausea, vomiting, dizziness, and drowsiness were noted. RESULT:Analysis revealed that time for rst analgesic requirement was signicantly longer with oral Etoricoxib 90 mg than with placebo. Pre-emptive oral Etoricoxib 90 mg decreases the severity of pain postoperatively but not signicantly as compared to placebo in patients posted for lumbar spine surgery under general anaesthesia. Oral Etoricoxib 90 mg had no signicant effect on cardiovascular and respiratory parameters. Patients receiving Etoricoxib had higher incidence of nausea, vomiting. CONCLUSION: that time for rst analgesic requirement was signicantly longer with oral Etoricoxib than placebo.

scholarly journals Oral Presentation I

2016 ◽  
Vol 8 (1) ◽  
pp. 1-7
Author(s):  
Özer Makay ◽  
Esra Yuksel ◽  
Asuman Sargin ◽  
Murat Ozdemir ◽  
Varlik Erol ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Loss ◽  
Pressure Fluctuations ◽  
Conventional Laparoscopy ◽  
Categorical Variables ◽  
Control Group ◽  
Complication Rates ◽  
Robot Assisted ◽  
Respiratory Parameters ◽  
Significant Difference

ABSTRACT BACKGROUND AND AIMS Minimally invasive surgery of the adrenal gland is widespread. Although reports demonstrate the safety and feasibility of robot-assisted adrenalectomy, the objective benefits are still unclear, compared to those of conventional laparoscopy. Recently, robot-assisted approach has also become possible for pheochromocytoma resection. Since cardiopulmonary changes during robot-assisted dissection of the pheochromocytoma patient has not been studied in detail, we aimed to assess these concerns, compared to the routine laparoscopic technique. METHODS In this case-control study, 19 consecutive robot-assisted adrenal resections were compared with a control group consisting of 14 conventional laparoscopic adrenalectomy. Patient characteristics and intraoperative hemodynamic and respiratory parameters were assessed. Groups were compared using the χ2 test for categorical variables and Student's t-test for continuous variables. Significance was considered p < 0.05. RESULTS The robot-assisted procedure was performed successfully in all patients, except one. The duration of the robot-assisted procedure, compared to the conventional laparoscopy group, was significantly longer (p < 0.05). Intraoperative blood loss was significantly less in the robot-assisted group (p < 0.05). Dissection of pheochromocytoma showed a significant difference between the groups, according to the incidence of intraoperative blood pressure fluctuations (p < 0.05). The robot-assisted approach resulted in less incidents. Other hemodynamic and respiratory parameters did not differ between groups significantly. There were no perioperative deaths. Complication rates and postoperative hospital stays were not significantly different. CONCLUSION Robot-assisted adrenalectomy is a safe and technically feasible procedure for a pheochromocytoma patient. Robot-assisted resection of pheochromocytoma minimized the occurrence of intraoperative blood pressure fluctuations and blood loss.

scholarly journals The Effects of Magnesium Sulfate with Lidocaine for Infraclavicular Brachial Plexus Block for Upper Extremity Surgeries

2020 ◽  
Vol 15 (01) ◽  
pp. e33-e39 ◽  
Author(s):  
Siavash Beiranvand ◽  
Arash Karimi ◽  
Majid Haghighat Shoar ◽  
Maryam Baghizadeh Baghdashti
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Postoperative Pain ◽  
Magnesium Sulfate ◽  
Normal Saline ◽  
Motor Block ◽  
Control Group ◽  
Case Group ◽  
Hemodynamic Parameters ◽  
Infraclavicular Block

Abstract Background An addition of analgesic to anesthetic agents is likely to increase the effects of anesthesia and reduce associated adverse outcomes. Several adjuvants are studied in this regard. The aim of this study is to investigate the effects of adding a magnesium adjunct to lidocaine for the induction of infraclavicular block. Methods Patients referred to Shohada Ashayer Hospital, Khorramabad, for wrist and hand surgery were enrolled in this study. The intervention/case group included patients who received 18 mL lidocaine (2%) + 2 mL magnesium sulfate (50%), 10 mL normal saline; control group: 18 mL lidocaine (2%) + 12 mL of normal saline. After the induction of ultrasound-guided infraclavicular block, parameters such as duration of reach with respect to complete sensory and motor block, hemodynamic parameters (hypotension and bradycardia), and postoperative pain, using visual analogue scale criteria, were measured. The obtained data were analyzed using a Bayesian path analysis model. Results A total of 30 patients were included in each group. In the case group, sensory and motor block was achieved for 12.136 ± 4.96 and 13 ± 3.589 minutes more than those in the control group. The duration of sedation and immobilization was 2.57 ± 0.764 minute and 4.66 ± 0.909 minutes lengthier in the case group. Regarding the hemodynamic parameters, blood pressure was 0.217 ± 5.031 and 1.59 ± 5.14 units lower in the case group, immediately following the block and the surgery. Similarly, heart rate was 0.776 ± 4.548 and 0.39 ± 3.987 units higher in the case group, after 30 minutes and 2 hours of the procedure. A decrease in the pain was seen at 8, 10, and 12 hours after the surgery, as compared with the control group. An addition of magnesium to lidocaine for infraclavicular block resulted in a significantly longer sedation and immobilization period and decreased postoperative pain at 12 hours. Conclusion Heart rate and blood pressure did not decrease significantly in the case group. It can be concluded that addition of magnesium sulfate to lidocaine can produce better anesthetic and analgesic outcomes with low-to-no adverse effects.

scholarly journals The Effects of 8-Week Aerobic Training Program on Respiratory and Circulatory Parameters of Female Swimmers Between 12-14 Years Old

2018 ◽  
Vol 6 (12) ◽  
pp. 202 ◽  
Author(s):  
Meltem Kilicaslan Kalkan ◽  
Onder Daglioglu
Keyword(s):  
Blood Pressure ◽  
Training Program ◽  
Vital Capacity ◽  
Aerobic Training ◽  
T Test ◽  
Control Group ◽  
Respiratory Parameters ◽  
Significant Difference ◽  
Experimental Group ◽  
Group Comparisons

The purpose of this study is to investigate the effect of 8-week aerobic training program on respiratory and circulatory parameters in female swimmers between 12-14 years old. A total of 22 female swimmers, who were between 12-14 years old and joined to the national competitions in the province of Gaziantep, participated as volunteers. The subjects were randomly divided into two groups as experimental group (n=11, age:13.12±0.69) and control group (n=11, age:12.56±0.53). Aerobic training program was applied to the experimental group 3 days a week for 8 weeks. Both groups continued their regular swimming trainings. Resting heart rate (RHR), systolic blood pressure (SBP), diastolic blood pressure (DBP) measurements of the subjects were performed as circulatory parameters before and after training. These values were measured by Omron M6 Comfort device. Measurements of vital capacity (VC), forced vital capacity (FVC), forced expiratory volume (FEV1) and forced expiratory rate (FEV1/FVC) were performed as respiratory parameters. These values were measured by M.E.C. Pocket Spiro USB-100 instruments. For statistical analysis of data, Paired Sample t test was used for intra-group comparisons, and the Independent Sample t test was used for inter-group comparisons. The level of significance was determined as p<0.05. In the study we performed, the values of RHR, SBP, DBP, VC, FVC, FEV1 and FEV1/FVC were found to be significant after the aerobic training program applied to the experimental group (p<0.05). The circulatory parameters of the control group showed significance at p<0.05 level in RHR value. There was no significant difference between SBP and DBP values (p>0.05). The respiratory parameters of the control group were significant in FVC and FEV1 values (p<0.05). There was no significant difference between VC and FEV1/FVC values (p>0.05). As a result, it is thought that aerobic trainings have positive effects on respiratory and circulatory parameters in swimmers. It can be said that regular aerobic training improves respiratory and circulatory parameters.

scholarly journals Use of priming principle in the induction dose requirement of propofol and its hemodynamic stability- A cross sectional study

2021 ◽  
Vol 8 (3) ◽  
pp. 367-372
Author(s):  
P Ramesh Kumar ◽  
S Suganya ◽  
A Mohanhariraj ◽  
P Jothianand ◽  
R Shankar
Keyword(s):  
Blood Pressure ◽  
Total Dose ◽  
Control Group ◽  
Induction Agent ◽  
Hemodynamic Parameters ◽  
Dose Requirement ◽  
Hemodynamic Stability ◽  
Priming Principle ◽  
Induction Dose ◽  
The Mean

In anesthesia propofol induction is administered at a dose of 2mg/kg as a single bolus and when given at this dose the commonest problem faced by the anesthetist is the sudden drop in the blood pressure, as the hypotensive effect of propofol is proportional to the dose and rate of administration.To study the effect of auto co-induction (priming principle) in the requirement of induction dose of propofol and the resulting hemodynamic parameters. A prospective randomized double blinded study was conducted for a period of one year in the department of anesthesia at a government medical college hospital in TamilNadu. A total of 60 patients were selected for our study and were randomly allocated into two groups of 30 each. Group A is the study group (priming) and group B is the control group (non-priming group). In the priming group, three minutes after premedication the co induction agent was administered (25% of the calculated dose of propofol) and two minutes later the patient received propofol at a rate of 30mg/10 sec until loss of vocalization was achieved. The hemodynamic parameters along with the total dose requirement of propofol and BIS values were monitored at regular intervals after induction.The mean total dose of propofol required among the priming group patients was 78.2 mg compared to the total dose requirement in the non-priming group which was 92.5 mg and the mean difference was found to be statistically significant. A statistically significant fall in the heart rate and blood pressure was observed at 1 min and 3 mins after induction in non priming group compared to priming group. By applying priming principle the induction dose of propofol was reduced by 14.25% with a good hemodynamic stability.

scholarly journals Evaluation of nicotine patch in pain control of patients undergoing laparoscopic cholecystectomy

2018 ◽  
Vol 45 (3) ◽  
Author(s):  
EUCLIDES DIAS MARTINS FILHO ◽  
CÉSAR FREIRE DE MELO VASCONCELOS ◽  
FERNANDO DE SANTA CRUZ OLIVEIRA ◽  
ADRIANO DA FONSECA PEREIRA ◽  
ÁLVARO ANTÔNIO BANDEIRA FERRAZ
Keyword(s):  
Blood Pressure ◽  
Laparoscopic Cholecystectomy ◽  
Oxygen Saturation ◽  
Pain Control ◽  
Nicotine Patch ◽  
Test Group ◽  
Control Group ◽  
Hemodynamic Parameters ◽  
Significant Difference ◽  
The Mean

ABSTRACT Objective: to analyze the effects of nicotine patch on pain control, occurrence of nausea and its hemodynamic repercussions in laparoscopic cholecystectomy procedures. Methods: we conducted an analytical, prospective, randomized, triple-blinded, clinical study between January and July 2017. The sample consisted of 17 patients who underwent laparoscopic cholecystectomy for the treatment of cholelithiasis. Nine patients used nicotine patch, and eight, placebo patch. The studied variables were pain, nausea, patient satisfaction, blood pressure, heart rate, oximetry and morphine rescue. Results: taking into account the pain and nausea parameters, there was no statistically significant difference between the groups (p>0.05). Also, the evaluation of rescue medication, both opioids and prokinetics, did not show any significant statistical difference between the groups. Among the hemodynamic parameters, there was only one statistically significant difference in the analysis of oxygen saturation and systolic blood pressure (SBP) six hours after surgery: the mean oxygen saturation was higher in the Test group (97.89 x 95.88) and the mean SBP was higher in the Control group (123.89 x 110.0). Conclusion: although pain levels were lower for nicotine within 24 hours, the action of nicotine and the need for rescue opioids in pain control were not statistically significant between the groups and at the time intervals studied. There was no clinical repercussion in the hemodynamic parameters.

scholarly journals Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers

2021 ◽  
Vol 17 (2) ◽  
pp. 320-325
Author(s):  
Kavitha Ukkirapandian ◽  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Muscle Strength ◽  
Tertiary Care ◽  
Night Shift ◽  
Control Group ◽  
Care Hospital ◽  
Shift Workers ◽  
Respiratory Parameters ◽  
Increased Risk

Night shifts work in particular is the most frequent reasons for circadian rhythm disruption and subsequent psychological and physiological disturbances, especially increased risk of cardiovascular and respiratory ailments compared to daytime workers. Alternate nostril breathing for about 15 minutes was known to have effect over cardiac, respiratory parameters and muscle strength. Hence aim is of interest to assess the effects of alternate nostril breathing (ANB) on cardiorespiratory parameters and muscle strength among the rotating shift workers in the tertiary care hospital. This observational study was carried out in the department of Physiology after getting institutional ethical committee clearance. Around 140 rotating night shift workers of both sex of age 25-40 years with normal BMI and 140 non-shift workers age, sex and BMI matched were selected as study and control group respectively. Heart rate, blood Pressure, respiratory rate, peak expiratory flow rate, respiratory endurance, respiratory burst test, muscle strength and fatigue were recorded before and after 15 minutes of ANB. Shift workers were found to have significantly altered systolic (P=0.000) and diastolic (P=0.002) blood pressure and heart rate (P= 0.010) compared to non-shift workers. All the cardiorespiratory parameters and muscle strength, fatigue was found to be significantly (P< 0.05) altered after ANB between both shift and non- shift workers. ANB can be used as a therapeutic module among the shift workers, to maintain their sound health and to improve their performance in the night duty.

scholarly journals Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers

2021 ◽  
Vol 17 (2) ◽  
pp. 320-330
Author(s):  
Karthika Priyadharshini Udaykumar ◽  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Muscle Strength ◽  
Tertiary Care ◽  
Night Shift ◽  
Control Group ◽  
Care Hospital ◽  
Shift Workers ◽  
Respiratory Parameters ◽  
Increased Risk

Night shifts work in particular is the most frequent reasons for circadian rhythm disruption and subsequent psychological and physiological disturbances, especially increased risk of cardiovascular and respiratory ailments compared to daytime workers. Alternate nostril breathing for about 15 minutes was known to have effect over cardiac, respiratory parameters and muscle strength. Hence aim is of interest to assess the effects of alternate nostril breathing (ANB) on cardiorespiratory parameters and muscle strength among the rotating shift workers in the tertiary care hospital. This observational study was carried out in the department of Physiology after getting institutional ethical committee clearance. Around 140 rotating night shift workers of both sex of age 25-40 years with normal BMI and 140 non-shift workers age, sex and BMI matched were selected as study and control group respectively. Heart rate, blood Pressure, respiratory rate, peak expiratory flow rate, respiratory endurance, respiratory burst test, muscle strength and fatigue were recorded before and after 15 minutes of ANB. Shift workers were found to have significantly altered systolic (P=0.000) and diastolic (P=0.002) blood pressure and heart rate (P= 0.010) compared to non-shift workers. All the cardiorespiratory parameters and muscle strength, fatigue was found to be significantly (P< 0.05) altered after ANB between both shift and non- shift workers. ANB can be used as a therapeutic module among the shift workers, to maintain their sound health and to improve their performance in the night duty.

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