scholarly journals Linking Bone Health and Psychological/Mental Health

Author(s):  
Saima Khan
Keyword(s):  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jose J. Gil-Cosano ◽  
Esther Ubago-Guisado ◽  
Maria J. Sánchez ◽  
Maria J. Ortega-Acosta ◽  
Maria E. Mateos ◽  
...  

Abstract Background New approaches on paediatric cancer treatment aim to maintain long-term health. As a result of radiotherapy, chemotherapy or surgery, paediatric cancer survivors tend to suffer from any chronic health condition. Endocrine dysfunction represents one of the most common issues and affects bone health. Exercise is key for bone mass accrual during growth, specifically plyometric jump training. The iBoneFIT study will investigate the effect of a 9-month online exercise programme on bone health in paediatric cancer survivors. This study will also examine the effect of the intervention on body composition, physical fitness, physical activity, calcium intake, vitamin D, blood samples quality of life and mental health. Methods A minimum of 116 participants aged 6 to 18 years will be randomized into an intervention (n = 58) or control group (n = 58). The intervention group will receive an online exercise programme and diet counselling on calcium and vitamin D. In addition, five behaviour change techniques and a gamification design will be implemented in order to increase the interest of this non-game programme. The control group will only receive diet counselling. Participants will be assessed on 3 occasions: 1) at baseline; 2) after the 9 months of the intervention; 3) 4 months following the intervention. The primary outcome will be determined by dual energy X-ray absorptiometry (DXA) and the hip structural analysis, trabecular bone score and 3D-DXA softwares. Secondary outcomes will include anthropometry, body composition, physical fitness, physical activity, calcium and vitamin D intake, blood samples, quality of life and mental health. Discussion Whether a simple, feasible and short in duration exercise programme can improve bone health has not been examined in paediatric cancer survivors. This article describes the design, rationale and methods of a study intended to test the effect of a rigorous online exercise programme on bone health in paediatric cancer survivors. If successful, the iBoneFIT study will contribute to decrease chronic health conditions in this population and will have a positive impact in the society. Trial registration Prospectively registered in isrctn.com: isrctn61195625. Registered 2 April 2020.


2015 ◽  
Vol 86 (11) ◽  
pp. e4.4-e4
Author(s):  
James Bashford ◽  
Eli Silber

In order to better inform local clinical practice, we collected primary data from our local MS population. We addressed important aspects concerning relapse management, bone health, mental health, sphincter dysfunction, symptom burden, recognition of comorbidities and pharmacological treatment. An emphasis was placed on discovering the extent of patient satisfaction with the local service.An 11-page patient questionnaire was distributed to consecutive consenting patients attending the MS clinic. A supplemental questionnaire was provided to those patients on regular natalizumab therapy. In total, 92 full and 22 natalizumab questionnaires were completed.Two particular areas highlighted for improvement with regards to patient management and patient education were bone and mental health:1. Only 26% of respondents confirmed having had a dual-energy X-ray absorptiometry (DEXA) scan. When asked if reduced ability in MS is an important risk factor for osteoporosis, only 44/92 patients confirmed they thought this was true.2. In the last year, 41% and 58% of respondents have suffered from depression and anxiety, respectively. Despite this, only a third of these patients received any treatment (pharmacological or non-pharmacological) for anxiety, depression or both.Encouragingly, 95% of those surveyed would recommend our MS service to a friend or family member.


Author(s):  
Katherine Macdonald ◽  
Jennifer Hannah ◽  
James Galloway

Rheumatoid arthritis (RA) is a systemic disease that while primarily affecting joints, can also involve multiple organs of body including the lungs, heart, and blood vessels, bone, muscle, skin, central, and peripheral nervous system, and bone marrow. In addition, RA impacts upon mental health and mood. The process by which extra-articular organs are involved is less well understood than the articular manifestations, but most effects are thought to be driven by similar immune disturbances that drive the disease of the synovium. The 10-year cumulative incidence of any non-articular manifestation is approximately 50%, although severe manifestations are less than 10%. The non-articular manifestations of RA remain a common complication of the disease that account for substantial morbidity and mortality. Annual review of cardiovascular risk factors, bone health, and mental health is important to prevent future morbidity. It is vital to remain vigilant to the development of pulmonary, ocular, infectious, dermatological, or malignant complications. Controlling RA disease burden is the mainstay of management of most extra-articular manifestations, but immunomodulatory therapies come with additional specific risks which include opportunistic infections, malignancies, liver, and haematological abnormalities. Working in close partnership with other specialties is valuable when looking after these complex patients.


2010 ◽  
Vol 9 (1) ◽  
pp. 59
Author(s):  
Polackwich AS ◽  
Tadros NN ◽  
Ostrowski KA ◽  
◽  
◽  
...  

Late onset hypogonadism (LOH) is an issue of increasing concern. Studies have shown the importance of testosterone in the maintenance of homeostasis, especially with respect to bone health, sexual function, diabetes, cardiovascular risk, mental health and cognition. Much of the dysfunction in hypogonadism can be reversed or improved with testosterone replacement therapy (TRT). Physicians worry about the possible consequences of TRT, especially regarding the prostate. By reviewing the literature, we have found there are significant benefits to TRT, and fears of adverse effects on the prostate are largely unfounded, though there is a great need for larger studies with longer periods of follow-up, especially to evaluate adverse events.


2020 ◽  
Vol 54 (2) ◽  
Author(s):  
Biljana Bajić ◽  
Svetlana Ristić ◽  
Marija Palibrk ◽  
Aleksandra Arnaut ◽  
Svetlana Ćurčić ◽  
...  

Objective. The aim of this paper is the influence of nutrition and pattern behaviors on bone health in people with mental health disorders. Methods. At the Clinic for Psychiatry of the Clinical Center of Kragujevac and at the Department of Neuropsychiatry of the Specialist-Consultative Service of Kragujevac Health Care Center a cross-sectional study has been conducted. The survey included 46 patients from the age of 22 to 81, both genders, with schizophrenia as a diagnosis for mental disorders and depression determined by a psychiatrist. Quantitative testing of calcium, magnesium, phosphorus, sodium and potassium has been performed by standard biochemical methods. Vitamin D has been determined by HPLC method (high performance/pressure liquid chromatography) i.e. by a liquid chromatography under high pressure. Results. In the whole group of patients tested, 58.7% of patients were physically active and the patients with schizophrenia (p = 0.026) were less physically active. Out of the total number, 67% of patients eat irregularly and this habit is more present in patients with schizophrenia (p = 0.003). In terms of the presence of certain nutrients, fish is more represented in the nutrition of people suffering from depression. Three patients (6.5%) reported osteoporosis in their medical history, one of whom had a spontaneous fracture. In the anamneses (6.5%) of the patients stated that their parents had had spontaneous bone fractures. Low values ​​of 25 (OH) D in the serum were present in both study groups. Conclusion. Unhealthy life styles, low level of Vitamin D found in people who have mental health disorders represent risk factors for the reduced bone mass. The results of our research indicate the need for timely identification of potential risk factors and improvement of prevention in order to raise awareness of the importance of healthy lifestyles and behavior modification.


2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 122-123
Author(s):  
P Tandon ◽  
A N Sasson ◽  
Z Gallinger

Abstract Background Inflammatory bowel disease (IBD) is a complex chronic disease and it is imperative that gastroenterologists are familiar with the unique needs of the IBD patient. An important part of management involves education surrounding the general health maintenance needs of this patient population, especially those on immunomodulator and biologic therapy or those being considered for such treatment. A recent study showed that Canadian GI trainees are uncomfortable managing preventative care in IBD including vaccinations and bone protection. Using educational videos for trainees to improve core knowledge of these concepts remains unclear. Aims Assess educational efficacy of a core training module on trainee confidence and knowledge on preventative care in IBD. Methods This study assessed a preventative care in IBD video used as an educational tool in the University of Toronto GI trainee program as part of the annual GI in-training objective structured clinical examination (OSCE). Prior to the OSCE, a randomly selected cohort of trainees were provided the preventative care video. The remaining trainees prepared for the OSCE as standard. At the OSCE, one station asked all trainees to address preventative care in IBD with a standardized patient. Following the OSCE, a standardized evaluation of trainee confidence and degree of knowledge on vaccination, cancer screening, bone health, and mental health in IBD patients was performed. These evaluations and OSCE score were then compared between both cohorts. Data was analyzed using a t-test and p<0.05 was considered significant. Results A total of 10 subjects took part in the study. 5 subjects were exposed to the video prior to the OSCE and 5 were not exposed. Overall total score for trainees who had seen the video prior to the OSCE had a mean score of 85.3% (38.4/45) compared to those who had not seen the video prior had a mean score of 65.3% (29.4/45) with a p = 0.03. Global score in those exposed to the video was 70% (3.5/5) compared to 48% (2.4/5) in the unexposed group with a p= 0.006. Upon assessment of individuals topics, there was a trend in improved knowledge of vaccination and mental health screening in those exposed vs. unexposed to the educational video (52.6% vs. 32.6%, and 80% vs. 20%, respectively). No significant difference was identified between groups with respect to cancer screening and bone health. Conclusions Our study shows evidence that use of educational videos was efficacious with respect to GI trainee confidence and knowledge surrounding key concepts in preventative care of IBD patients. This exposure allows for improved patient education and management and lead to better-quality patient care. Overall, this study identifies a knowledge gap in trainee education and highlights the need for development of training tools to improve overall management of this complex and dynamic disease. Funding Agencies CAGVideo was a CAG accredited educational material, and supported by an educational grant from the Canadian Association of Gastroenterology and Abbvie Canada


2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


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