scholarly journals Pengaruh Therapeutic Exercise Walking terhadap Sirkulasi Darah Perifer pada Pasien Diabetes Melitus Tipe 2 di Kelurahan Gebang Kecamatan Patrang Kabupaten Jember. (The Effect of Therapeutic Exercise Walking on Pheripheral Blood Circulation in Patients wit

2020 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Erti Ikhtiarini Dewi ◽  
Amadea Yollanda ◽  
Nur Widayati ◽  
Rondhianto Rondhianto
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Peripheral Blood ◽  
Blood Circulation ◽  
Control Group ◽  
Therapeutic Exercise ◽  
Peripheral Blood Circulation

Pathological change experienced by patients with type 2 diabetes mellitus is impaired peripheralblood circulation, especially in the lower limbs and feet. Peripheral blood circulation can be examinedby measuring Ankle Brachial Index (ABI). Therapeutic exercise walking is one of physical activitieswhich can improve blood circulation. This research goal was to analyze the effect of therapeuticexercise walking on peripheral blood circulation in patients with type 2 diabetes mellitus. Theresearch design was randomized control group pretest-posttest design. The sample size was 15respondents as control group and 15 respondents as treatment group. Data was analyzed by usingdependent t-test and independent t-test with significant level of 0.05. This result showed a significantincrease of ABI after therapeutic exercise walking in the treatment group (p= 0.001). However therewas a significant decrease of ABI between pretest and posttest in control group (p=0.010).Independent t-test indicated a significant difference of ABI between treatment group and controlgroup (p=0.000). So, it can be concluded that there is an influence of therapeutic exercise walking onthe peripheral blood circulation in patients with type 2 diabetes mellitus. Nurses should applytherapeutic exercise walking to improve peripheral blood circulation in patients with type 2 diabetesmellitus.Keywords: type 2 diabetes mellitus, therapeutic exercise walking, ankle brachial index

scholarly journals EFEKTIVITAS SPA KAKI DIABETIK TERHADAP SIRKULASI DARAH PERIFER PADA PASIEN DIABETES MELLITUS TIPE 2 DI WILAYAH KERJA PUSKESMAS WONOKROMO SURABAYA

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Rahmi Affiani ◽  
Puji Astuti
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Group ◽  
Diabetic Foot ◽  
Peripheral Blood ◽  
Blood Circulation ◽  
Control Group ◽  
Public Health Centre ◽  
Study Results ◽  
Peripheral Blood Circulation

Diabetes mellitus type 2 is often occur and became chronic complication of vascular peripheral disease caused by decreasing peripheral blood circulation. One of therapy to improve peripheral blood circulation is diabetic foot spa, The purpose of this study is to find out the effectiveness of diabetic foot spa towards peripheral blood circulation. Design of this study is Quasy-Experiment. The population were all diabetes mellitus patients type 2 in Public Health Centre Wonokromo Surabaya. Number of sample was 46 person, divided into 2 group, that are treatment group and control group, with 23 person each group, taken by purposive sampling technique. Data analyzed by Mann-Whitney test with α=0.05. Study results on treatment group before giving diabetic foot spa majority (52.2%) of peripheral blood circulation in mild category and for control group mostly (60.9%) have blood circulation in mild category as well. After the foot spa was give to the treatment group, almost entirely (91.3%) had normal peripheral blood circulation, whereas in the control group majority (73.9%) remain mild. Analysis of MannWhitney test P=0.000 < α=0.05, which means diabetic foot spa is effective towards blood circulation. The more frequent perform of diabetic foot spa, the better peripheral blood circulation, it can prevent complications of diabetes mellitus.

scholarly journals Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia

2020 ◽  
Author(s):  
Xiaomeng Sun ◽  
Jia Liu ◽  
Guang Wang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Diabetic Patients ◽  
Fenofibrate Treatment

Abstract Background: This study was to research the efficacy of fenofibrate in the treatment of microalbuminuria in the patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia. Methods: Type 2 diabetic patients (56) with microalbuminuria and hypertriglyceridemia aged 30 to 75 were randomly divided into the fenofibrate treatment group(n=28) and the control group (n=28) for 180 days. Urinary microalbumin /creatinine ratio (UACR) and other metabolic parameters were compared at baseline, during treatment and after treatment. Results: After 180 days, the reduction of levels of fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) in two groups were no differences. In treatment group, uric acid (UA) (296.42 ± 56.41 vs 372.46 ± 72.78), triglyceride (TG) [1.51(1.17, 2.06) vs 3.04(2.21, 3.29)], and UACR [36.45 (15.78,102.41) vs 129.00 (53.00, 226.25)] were significantly decreased compared with the baseline. The high-density lipoprotein cholesterol (HDL-C) levels were significantly increased (1.22 ± 0.26 vs 1.09 ± 0.24) compared with the baseline. The decrease in UACR [-44.05(-179.47, -12.16) vs -8.15(-59.69, 41.94)]in treatment group was significantly higher compared with the control group. The decrease in UACR was positively associated with the decreases in TG ( r = 0.447, P = 0.042) and UA ( r = 0.478, P = 0.024) after fenofibrate treatment. Conclusion: In the patients with hypertriglyceridemia and type 2 diabetes mellitus, fenofibrate can improve microalbuminuria and do not increase the deterioration of glomerular filtration rate

scholarly journals The Effect of Tempe Dietary Intake on Plasma Glucose Level in Elderly Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 1 (6) ◽  
Author(s):  
Grace Puspasari ◽  
Drupadi Dillon ◽  
Budiman Budiman
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Plasma Glucose Level ◽  
Daily Intake ◽  
Control Group

The aim of the study was to investigate  the effect of daily intake of 100 grams tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial. Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study subjects were assigned to two groups using block randomization. All subjects had to take diabetic regiment with calorie and macronutrient following diabetic recommendation diet. The treatment group (n=16) received tempe, while control group (n=14) received legumes other than tempe. Fasting plasma glucose level (FPG) was assessed before and after intervention. Unpaired t test and Mann Whitney were used to analyzed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Both group were comparable in age, gender, BMI, calorie and macronutrient intake before treatment. Fat, fiber, and isoflavone intake were significantly higher in treatment group compare to control group. Decrease in FPG after intervention were observed but were statisticaly insignificant. In conclusion daily intake of 100 grams tempe for four weeks did not decrease FPG.  Keywords: elderly, plasma glucose level, tempe, type 2 diabetes

scholarly journals THE EFFECT OF PUGUNTANO (CURANGA FEL-TERRAE [LOUR.]) EXTRACT ON ADIPONECTIN RECEPTOR (ADIPOR) IN RATS WITH TYPE 2 DIABETES MELLITUS

2019 ◽  
pp. 551-553
Author(s):  
DHARMA LINDARTO ◽  
YETTY MACHRINA ◽  
SANTI SYAFRIL ◽  
AWALUDDIN SARAGIH
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Body Weight ◽  
Treatment Group ◽  
Control Group ◽  
Model Assessment ◽  
Anti Inflammatory

Objective: This study aimed to determine whether the antidiabetic effects of puguntano (Curanga fel-terrae [Lour.]) extract involve anti-inflammatory effects mediated through adiponectin receptors (AdipoRs). Methods: Type 2 diabetes mellitus (T2DM) Wistar rats were induced by a combination of high-fat diet for 5 weeks and injection small dose streptozotocin 30 mg/kg bw/rat. This study was conducted in 48 T2DM rats, which were randomly assigned into two weight-matched groups (n=24, each). Only the treatment group received 0.2 mg/g bw of puguntano extract suspension through oral for 10 days. The clinical characteristics of T2DM and AdipoR were assessed before and after the treatment period. Results: The treatment group demonstrated significantly lower body weight, fasting blood glucose, and homeostasis model assessment-insulin resistance (HOMA-IR) but higher AdipoR than the control group (all, p<0.001). Furthermore, there were also negative correlations between AdipoR to body weight and HOMA-IR (all, p<0.05). Conclusion: Our data suggest that puguntano could improve glucose metabolism and ameliorate insulin resistance and have anti-inflammatory effects mediated through AdipoR in T2DM.

scholarly journals Hsa_circ_0054633 in Peripheral Blood Can be Used as a Diagnostic Biomarker of Pre-Diabetes and Type 2 Diabetes Mellitus

2016 ◽  
Author(s):  
Muwei Li ◽  
Zhenzhou Zhao ◽  
Xuejie Li ◽  
Chuanyu Gao ◽  
Dongdong Jian ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Peripheral Blood ◽  
Circular Rnas ◽  
Control Group ◽  
Diabetes Group ◽  
Screening Criteria ◽  
Expression Characteristic

The purpose of current study was to investigate the expression characteristic of circular RNAs (circRNAs) in peripheral blood of type 2 diabetes mellitus (T2DM) patients and their potentials as diagnostic biomarkers for pre-diabetes and T2DM. In present study, the circRNAs in the peripheral blood from 6 healthy individuals and 6 T2DM patients were collected for microarray analysis. The results indicated that there were 489 differentially expressed circRNAs, of which 78 were upregulated and 411 were downregulated in the T2DM group. Then we selected 5 circRNAs as the candidate biomarkers under a stricter screening criteria and further verified them in another cohort (control group, n=20; pre-diabetes group, n =20; T2DM group; n=20). 3 of the 5 circRNAs presented upregulated expression in the experimental groups, including 2 circRNAs of the T2DM group that had higher expression than the pre-diabetes group. Hsa_circ_0054633 was identified to have the largest area value under the carve (AUC). In another independent cohort (control group, n=60; pre-diabetes group, n=63; T2DM group, n=64), the diagnostic capacity of hsa_circ_0054633 was tested. The results showed that the AUC for the diagnosis of pre-diabetes was 0.751(95% confidence interval=[0. 666-0.835], P＜0.001) while it was 0.793 ([0.716-0.871], P＜0.001) for the diagnosis of T2DM. After including the risk factors of T2DM, the AUC increased to 0.841 ([0.773-0.910], P &lt;0.001) and 0.834 ([0.762-0.905], P &lt;0.001), respectively. Hsa_circ_0054633 presented a certain diagnostic capability for pre-diabetes and T2DM.

scholarly journals Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia

2020 ◽  
Author(s):  
Xiaomeng Sun ◽  
Jia Liu ◽  
Guang Wang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients

Abstract Background: This study was to research the efficacy of fenofibrate in the treatment of microalbuminuria in the patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia.Methods: Type 2 diabetic patients (56) with microalbuminuria and hypertriglyceridemia aged 30 to 75 were randomly divided into the fenofibrate treatment group(n=28) and the control group (n=28) for 180 days. Urinary microalbumin /creatinine ratio (UACR) and other metabolic parameters were compared at baseline, during treatment and after treatment.Results: After 180 days, the reduction of levels of fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) in two groups were no differences. In treatment group, uric acid (UA) (296.42 ± 56.41 vs 372.46 ± 72.78), triglyceride (TG) [1.51(1.17, 2.06) vs 3.04(2.21, 3.29)], and UACR [36.45 (15.78,102.41) vs 129.00 (53.00, 226.25)] were significantly decreased compared with the baseline. The high-density lipoprotein cholesterol (HDL-C) levels were significantly increased (1.22 ± 0.26 vs 1.09 ± 0.24) compared with the baseline. The decrease in UACR [-44.05(-179.47, -12.16) vs -8.15(-59.69, 41.94)]in treatment group was significantly higher compared with the control group. The decrease in UACR was positively associated with the decreases in TG ( r = 0.447, P = 0.042) and UA ( r = 0.478, P = 0.024) after fenofibrate treatment.Conclusion: In the patients with hypertriglyceridemia and type 2 diabetes mellitus, fenofibrate can improve microalbuminuria and do not increase the deterioration of glomerular filtration rate

ESTIMATION OF SERUM FERRITIN LEVELS IN TYPE 2 DIABETIC PATIENTS AND ITS RELATION WITH HbA1C LEVEL.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Shah Namrata Vinubhai ◽  
Pardeep Agarwal ◽  
Bushra Fiza ◽  
Ramkishan Jat
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Serum Ferritin ◽  
Inflammatory Marker ◽  
Control Group ◽  
Diabetic Patients ◽  
Positive Correlation

Background: Serum ferritin is known as an index for body iron stores also as an inflammatory marker and it is influenced by several disease. We were looking for a correlation between HbA1c and S. Ferritin in type 2 DM. Methodology: The present study a total of 150 participants were enrolled of which 100 were confirmed cases of Type 2 Diabetes Mellitus and rest 50 age and sex matched healthy subjects constituted the control group. All were screened for HbA1c, Fasting blood sugar, Post prandial blood sugar and S.Ferritin. Results: A highly significant variation and positive correlation was observed with respect to S.Ferritin and HbA1c levels. Mean S.Ferritin was high in the subgroup with poor glycemic control. Conclusion: The fasting, post prandial sugar levels, HbA1c and S.Ferritin were significantly higher in the diabetic subjects. This study shows a positive correlation between HbA1c and S. Ferritin levels. So we can conclude that in diabetic patients S. Ferritin may serve as an independent marker of poor glycemic and metabolic control. Keywords: Serum ferritin, Type 2 Diabetes Mellitus, HbA1c.

Rheumatoid Factor in Type 2 Male Diabetes Mellitus Patients in a Tertiary Care Hospital of Bangladesh

2018 ◽  
Vol 4 (2) ◽  
pp. 58-62
Author(s):  
Roksana Yeasmin ◽  
MA Muttalib ◽  
Kazi Nazneen Sultana ◽  
Nizamul Hoque Bhuiyan ◽  
Md Jamil Hasan Karami ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Rheumatoid Factor ◽  
Serum Uric Acid ◽  
Control Group ◽  
Healthy Male ◽  
Male Patients

Background: Type 2 diabetes mellitus is a chronic disease characterized by relative or absolute deficiency of insulin, resulting in glucose intolerance.Objectives: The present study was planned to see the associations of serum uric acid with positive Rheumatoid factor in type 2 male diabetes mellitus patients. Methodology: This case control study was carried out at the department of Biochemistry at Ibrahim Medical College, Dhaka, Bangladesh. The duration of the study was from June 2015 to June 2016 for a period of one year. In this present study, male patients with type 2 diabetes mellitus were taken as case group and age and sex matched healthy male were taken as control group. Rheumatoid factor was measured from the blood of all case and control group respondents. Others blood para meters were also measured for the correlation with the diabetes mellitus patients.Results: In this present study, 110 male patients presented with type 2 diabetes mellitus were recruited as case and age and sex matched healthy male were recruited as control. More rheumatoid factor positive in type 2 DM male patients with the uric acid range between 6.5 to 9.5 mg/dL. The number of patients was 5 out of total 9 rheumatoid factor positive cases. In this study serum uric acid was significantly correlated with rheumatoid factor in type 2 male diabetic patients. Rheumatoid factor positive cases were taking insulin among 9 and it was statistically significantly associated (p<0.001). Conclusion: In this study serum uric acid is significantly associated with positive rheumatoid factor in type 2 male diabetic patients.Journal of Current and Advance Medical Research 2017;4(2):58-62

scholarly journals Fermented pork fat (Sa-um) and lifestyle risk factors as potential indicators for type 2 diabetes among the Mizo population, Northeast India

2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Freda Lalrohlui ◽  
Souvik Ghatak ◽  
John Zohmingthanga ◽  
Vanlal Hruaii ◽  
Nachimuthu Senthil Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cox Regression ◽  
Control Group ◽  
Diabetic Patients ◽  
Lifestyle Habits ◽  
Pork Fat

AbstractOver the last few decades, Mizoram has shown an increase in cases of type 2 diabetes mellitus; however, no in-depth scientific records are available to understand the occurrence of the disease. In this study, 500 patients and 500 healthy controls were recruited to understand the possible influence of their dietary and lifestyle habits in relation with type 2 diabetes mellitus. A multivariate analysis using Cox regression was carried out to find the influence of dietary and lifestyle factors, and an unpaired t test was performed to find the difference in the levels of biochemical tests. Out of 500 diabetic patients, 261 (52.3%) were males and 239 (47.7%) were females, and among the control group, 238 (47.7%) were males and 262 (52.3%) were females. Fermented pork fat, Sa-um (odds ratio (OR) 18.98), was observed to be a potential risk factor along with tuibur (OR 0.1243) for both males and females. Creatinine level was found to be differentially regulated between the male and female diabetic patients. This is the first report of fermented pork fat and tobacco (in a water form) to be the risk factors for diabetes. The unique traditional foods like Sa-um and local lifestyle habits like tuibur of the Mizo population may trigger the risk for the prevalence of the disease, and this may serve as a model to study other populations with similar traditional practices.

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