scholarly journals EFEKTIVITAS SPA KAKI DIABETIK TERHADAP SIRKULASI DARAH PERIFER PADA PASIEN DIABETES MELLITUS TIPE 2 DI WILAYAH KERJA PUSKESMAS WONOKROMO SURABAYA

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Rahmi Affiani ◽  
Puji Astuti
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Group ◽  
Diabetic Foot ◽  
Peripheral Blood ◽  
Blood Circulation ◽  
Control Group ◽  
Public Health Centre ◽  
Study Results ◽  
Peripheral Blood Circulation

Diabetes mellitus type 2 is often occur and became chronic complication of vascular peripheral disease caused by decreasing peripheral blood circulation. One of therapy to improve peripheral blood circulation is diabetic foot spa, The purpose of this study is to find out the effectiveness of diabetic foot spa towards peripheral blood circulation. Design of this study is Quasy-Experiment. The population were all diabetes mellitus patients type 2 in Public Health Centre Wonokromo Surabaya. Number of sample was 46 person, divided into 2 group, that are treatment group and control group, with 23 person each group, taken by purposive sampling technique. Data analyzed by Mann-Whitney test with α=0.05. Study results on treatment group before giving diabetic foot spa majority (52.2%) of peripheral blood circulation in mild category and for control group mostly (60.9%) have blood circulation in mild category as well. After the foot spa was give to the treatment group, almost entirely (91.3%) had normal peripheral blood circulation, whereas in the control group majority (73.9%) remain mild. Analysis of MannWhitney test P=0.000 < α=0.05, which means diabetic foot spa is effective towards blood circulation. The more frequent perform of diabetic foot spa, the better peripheral blood circulation, it can prevent complications of diabetes mellitus.

scholarly journals Pengaruh Therapeutic Exercise Walking terhadap Sirkulasi Darah Perifer pada Pasien Diabetes Melitus Tipe 2 di Kelurahan Gebang Kecamatan Patrang Kabupaten Jember. (The Effect of Therapeutic Exercise Walking on Pheripheral Blood Circulation in Patients wit

2020 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Erti Ikhtiarini Dewi ◽  
Amadea Yollanda ◽  
Nur Widayati ◽  
Rondhianto Rondhianto
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Peripheral Blood ◽  
Blood Circulation ◽  
Control Group ◽  
Therapeutic Exercise ◽  
Peripheral Blood Circulation

Pathological change experienced by patients with type 2 diabetes mellitus is impaired peripheralblood circulation, especially in the lower limbs and feet. Peripheral blood circulation can be examinedby measuring Ankle Brachial Index (ABI). Therapeutic exercise walking is one of physical activitieswhich can improve blood circulation. This research goal was to analyze the effect of therapeuticexercise walking on peripheral blood circulation in patients with type 2 diabetes mellitus. Theresearch design was randomized control group pretest-posttest design. The sample size was 15respondents as control group and 15 respondents as treatment group. Data was analyzed by usingdependent t-test and independent t-test with significant level of 0.05. This result showed a significantincrease of ABI after therapeutic exercise walking in the treatment group (p= 0.001). However therewas a significant decrease of ABI between pretest and posttest in control group (p=0.010).Independent t-test indicated a significant difference of ABI between treatment group and controlgroup (p=0.000). So, it can be concluded that there is an influence of therapeutic exercise walking onthe peripheral blood circulation in patients with type 2 diabetes mellitus. Nurses should applytherapeutic exercise walking to improve peripheral blood circulation in patients with type 2 diabetesmellitus.Keywords: type 2 diabetes mellitus, therapeutic exercise walking, ankle brachial index

scholarly journals Efektifitas Foot Spa Diabetic terhadap Nilai Ankle Brachial Index pada Pasien Diabetes Mellitus Tipe II

2019 ◽  
Vol 3 (1) ◽  
pp. 312-321
Author(s):  
Rizkan Halalan Djafar ◽  
Busjra M. Nur ◽  
Rohman Azzam
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Group ◽  
Diabetic Foot ◽  
Health Centre ◽  
Ankle Brachial Index ◽  
Public Health Centre ◽  
Whitney Test ◽  
Mann Whitney Test ◽  
Study Results

The purpose of this study is to find out the effectiveness of diabetic foot spa towards ankle brachial index. Design of this study is Quasy-Experiment with two group. The population were all diabetes mellitus patients type 2 in Public Health Centre Wawonasa Manado. Number of sample was 32 person, divided into 2 group, that are treatment group during 3 and 5 time, with 16 person each group, taken by purposive sampling technique. Data analyzed by Mann-Whitney test with α=0.05. Study results on difference between ABI treatment 3 dan 5 time. Analysis of Mann-Whitney test P=0.112> α=0.05, with average ABI in treatment group during 3 and 5 time pre test 0.012 and post test 0.0562, which means diabetic foot spa 3 and 5 time is effective towards ABI.   Keywords: Ankle Brachial Index, DM Type 2, Foot Spa Diabetic

scholarly journals Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia

2020 ◽  
Author(s):  
Xiaomeng Sun ◽  
Jia Liu ◽  
Guang Wang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Diabetic Patients ◽  
Fenofibrate Treatment

Abstract Background: This study was to research the efficacy of fenofibrate in the treatment of microalbuminuria in the patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia. Methods: Type 2 diabetic patients (56) with microalbuminuria and hypertriglyceridemia aged 30 to 75 were randomly divided into the fenofibrate treatment group(n=28) and the control group (n=28) for 180 days. Urinary microalbumin /creatinine ratio (UACR) and other metabolic parameters were compared at baseline, during treatment and after treatment. Results: After 180 days, the reduction of levels of fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) in two groups were no differences. In treatment group, uric acid (UA) (296.42 ± 56.41 vs 372.46 ± 72.78), triglyceride (TG) [1.51(1.17, 2.06) vs 3.04(2.21, 3.29)], and UACR [36.45 (15.78,102.41) vs 129.00 (53.00, 226.25)] were significantly decreased compared with the baseline. The high-density lipoprotein cholesterol (HDL-C) levels were significantly increased (1.22 ± 0.26 vs 1.09 ± 0.24) compared with the baseline. The decrease in UACR [-44.05(-179.47, -12.16) vs -8.15(-59.69, 41.94)]in treatment group was significantly higher compared with the control group. The decrease in UACR was positively associated with the decreases in TG ( r = 0.447, P = 0.042) and UA ( r = 0.478, P = 0.024) after fenofibrate treatment. Conclusion: In the patients with hypertriglyceridemia and type 2 diabetes mellitus, fenofibrate can improve microalbuminuria and do not increase the deterioration of glomerular filtration rate

scholarly journals The Influence of Diabetic Foot Exercise in Sensory Peripheral Neuropathy with Monofilament Test on Diabetes Mellitus Clients

Jurnal NERS ◽  
2020 ◽  
Vol 14 (3) ◽  
pp. 340
Author(s):  
Tintin Sukartini ◽  
Candra Panji Asmoro ◽  
Nandani Alifah
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Treatment Group ◽  
Diabetic Foot ◽  
Rank Test ◽  
Control Group ◽  
Sensory Peripheral Neuropathy ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test

Background: Peripheral neuropathy is a long-term complication that attacks the nerves and loses the sensation of protection which affects about 50% of people with diabetes mellitus (DM). Diabetic foot exercises can help blood circulation, especially in the legs or lower limbs. This researched aimed to analyze the effect of diabetic foot exercise on sensory peripheral neuropathy in DM clients.Method: The study design used quasi-experimental pre-post test with control group. Samples were 28 respondents using purposive sampling and divided into two groups of 14 respondents each. The independent variable is diabetic foot training, and the dependent variable is peripheral sensory neuropathy. Interventions are carried out 3 times a week for 4 weeks. The research instrument was Weinstein Monofilament 10 g Semmes and a diabetic foot training checklist. Data analysis using the Wilcoxon-signed rank test and Mann Whitney test with α≤0.05.Result: The Wilcoxon-signed rank test in the treatment group showed differences in sensory peripheral neuropathy after treatment (p=0,000) and no difference in the control group (p=0.564). The Mann Whitney test results showed differences in sensory peripheral neuropathy between the treatment group and the control group after treatment p=0.039.Conclusion: Diabetic foot exercises can be used as an alternative measure to improve sensory peripheral neuropathy.

scholarly journals UHPLC-MS-Based Serum and Urine Metabolomics Reveals the Anti-Diabetic Mechanism of Ginsenoside Re in Type 2 Diabetic Rats

Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6657
Author(s):  
Heyu Wang ◽  
Yaran Teng ◽  
Shinan Li ◽  
Ying Li ◽  
Hui Li ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Treatment Group ◽  
Metabolic Pathways ◽  
Biochemical Parameters ◽  
Control Group ◽  
Potential Mechanism ◽  
Ginsenoside Re ◽  
Serum And Urine

Panax ginseng was employed in the treatment of “Xiao-Ke” symptom, which nowadays known as diabetes mellitus, in traditional Chinese medicine for more than a thousand years. Ginsenoside Re was the major pharmacologic ingredient found abundantly in ginseng. However, the anti-diabetic of Ginsenoside Re and its underlying mechanism in metabolic level are still unclear. Serum and urine metabolomic method was carried out to investigate the anti-diabetic pharmacological effects and the potential mechanism of Ginsenoside Re on high-fat diet combined streptozotocin-induced type 2 diabetes mellitus (T2DM) rats based on ultra-high-performance liquid chromatography coupled with quadrupole exactive orbitrap mass spectrometry (UHPLC-Q-Exactive Orbitrap/MS). Serum and urine samples were collected from the control group (CON), T2DM group, metformin (MET) treatment group, and ginsenoside Re treatment group after intervention. The biochemical parameters of serum were firstly analyzed. The endogenous metabolites in serum and urine were detected by UHPLC-MS. The potential metabolites were screened by multivariate statistical analysis and identified by accurate mass measurement, MS/MS, and metabolite databases. The anti-diabetic-related metabolites were analyzed by KEGG metabolic pathway, and its potential mechanism was discussed. The treatment of ginsenoside Re significantly reduced the blood glucose and serum lipid level improved the oxidative stress caused by T2DM. Biochemical parameters (urea nitrogen, uric acid) showed that ginsenoside Re could improve renal function in T2DM rats. Respective 2 and 6 differential metabolites were found and identified in serum and urine of ginsenoside Re compared with T2DM group and enriched in KEGG pathway. Metabolic pathways analysis indicated that the differential metabolites related to T2DM were mainly involved in arachidonic acid metabolism, Vitamin B6, steroid hormone biosynthesis, and bile secretion metabolic pathways. This study verified the anti-diabetic and anti-oxidation effects of ginsenoside Re, elaborated that ginsenoside Re has a good regulation of the metabolic disorder in T2DM rats, which could promote insulin secretion, stimulated cannabinoid type 1 receptor (CB1), and CaMKK β to activate AMPK signaling pathway, inhibited insulin resistance, and improved blood glucose uptake and diabetic nephropathy, so as to play the role of anti-diabetic.

scholarly journals The Effect Of Diabetic Foot Spa On Ankle Brachial Index And Foot Sensitivity Of Diabetes Mellitus Type 2

2019 ◽  
Vol 6 (3) ◽  
pp. 672
Author(s):  
Erika Martining Wardani ◽  
Lono Wijayanti ◽  
Nur Ainiyah
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Diabetes Mellitus Type 2 ◽  
Ankle Brachial Index ◽  
Sampling Technique ◽  
Diabetes Mellitus Type ◽  
Control Group ◽  
P Value ◽  
Control Group Design

Diabetes Mellitus (DM) is a metabolic disorder which marked by the hyperglycemia that appeared because of insulin secretion disorder and/or the increase of cellular insulin resistance. DM patients have a higher risk to experience foot problems due to blood vessels disorders causing the circulation of blood from legs is decreased. Purposed this research is diabetes could be prevented by doing a foot spa diabetic which the activities include foot exercises, warm water cleansing and massage. The method used in this study is Quays Experiment pre-post control group design. The population on this study was patients with Diabetes Mellitus Type 2 in Waru health center. The sample used was 60 people, divided into 2 groups; intervention and control group, with sampling technique of simple random sampling. The data collection was using observation sheets of diabetic foot SPA; the tool used to assess blood glucose levels was glucometer, whereas cotton, brush and needle were used to assess the foot sensitivity. The data was then analyzed with t-test. The result of the study showed that there were effecton the foot sensitivity (t=10,73, p value =0, 000) and there were effectdecrese on ankle brachial index(t=12,34, p value =0, 000). It is important for families and communities to give motivation to the diabetes mellitus patients to do diabetic foot SPA as one of alternative therapies to prevent foot complications such as foot ulcers and even amputation

scholarly journals Experience in using nucleotides for the management Of patients with diabetic polyneuropatie

2018 ◽  
pp. 24-28
Author(s):  
G. N. Belskaya ◽  
L. G. Krylova ◽  
L. A. Sergienko ◽  
S. B. Stepanova ◽  
L. D. Makarova
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Polyneuropathy ◽  
Control Group ◽  
Basic Therapy ◽  
Neuropathic Symptom ◽  
Study Results ◽  
Diabetes Mellitus Management

Diabetic polyneuropathy (DPN) is one of the most common complications of diabetes mellitus. Management of patients with DPN is a complex medical and socioeconomic problem. The article presents the observational study results of 40 patients with type 2 diabetes mellitus complicated by DPN. Patients of the treatment group received Keltikan® complex in combination with basic therapy for 60 days, patients of the control group received only basic therapy. The treatment resulted in the positive changes observed in both groups, while the group taking Keltikan® complex showed more pronounced changes according to the total neurological symptoms (TSS) scale, the neuropathic dysfunctional score (NDS) scale, the neuropathic symptom score (NSS) scale, and also according to the electroneuromyography results. 

scholarly journals Uji Efektivitas Beras Herbal Forte terhadap Penurunan Kadar Glukosa Darah Pasien Diabetes Melitus Tipe 2 (Study of the Herbal Rice Forte Effectiveness on Decreasing Blood Glucose of Diabetes Mellitus Type 2 Patient)

2018 ◽  
Vol 6 (1) ◽  
pp. 85
Author(s):  
Gema Akbar Wakhidana ◽  
Ancah Caesarina Novi Marchianti ◽  
Ali Santosa
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Treatment Group ◽  
Metabolic Diseases ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Type 2 Dm

Diabetes mellitus is metabolic diseases characterized by hyperglycemia caused by disturbances in insulin secretion or insulin activity. Herbal Forte Rice is rice synthetic material composed of main purple sweet potato and corn flour. It contains antioksidan, fiber, resistant starch and having moderate glycemic index. This study aimed to determine the effectivity of Herbal Forte Rice on decreasing blood glucose levels of patients type 2 DM. It used a cross-over design, the role of research subjects was both as control and treatment groups. Total sample of this research consisted of 60 samples. The treatment group was given Herbal Forte Rice for 7 days in 2 consecutive meals, while the control group did not receive any intervention. The results showed the average level of Fasting Blood Glucose (FBG) beginning and end of the treatment group 179.76 mg/dL and 138.7 mg/dL; FBG beginning and end of the control 180.87 mg/dL and 187.63 mg/dL; 2 hours post prandial Blood Glucose (2hppBG) levels of beginning and end of the treatment group 284.37 mg/dL and 183.8 mg/dL; 2hppBG levels beginning and end of the control 280.57 mg/dL and 284.13 mg/dL. This study concludes that Herbal Forte Rice effective on decreasing blood glucose levels of patients type 2 DM.   Keywords: diabetes mellitus, Rice Herbal Forte, GDP and GD2PP  

scholarly journals The Effect of Tempe Dietary Intake on Plasma Glucose Level in Elderly Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 1 (6) ◽  
Author(s):  
Grace Puspasari ◽  
Drupadi Dillon ◽  
Budiman Budiman
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Plasma Glucose Level ◽  
Daily Intake ◽  
Control Group

The aim of the study was to investigate  the effect of daily intake of 100 grams tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial. Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study subjects were assigned to two groups using block randomization. All subjects had to take diabetic regiment with calorie and macronutrient following diabetic recommendation diet. The treatment group (n=16) received tempe, while control group (n=14) received legumes other than tempe. Fasting plasma glucose level (FPG) was assessed before and after intervention. Unpaired t test and Mann Whitney were used to analyzed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Both group were comparable in age, gender, BMI, calorie and macronutrient intake before treatment. Fat, fiber, and isoflavone intake were significantly higher in treatment group compare to control group. Decrease in FPG after intervention were observed but were statisticaly insignificant. In conclusion daily intake of 100 grams tempe for four weeks did not decrease FPG.  Keywords: elderly, plasma glucose level, tempe, type 2 diabetes

scholarly journals THE EFFECT OF PUGUNTANO (CURANGA FEL-TERRAE [LOUR.]) EXTRACT ON ADIPONECTIN RECEPTOR (ADIPOR) IN RATS WITH TYPE 2 DIABETES MELLITUS

2019 ◽  
pp. 551-553
Author(s):  
DHARMA LINDARTO ◽  
YETTY MACHRINA ◽  
SANTI SYAFRIL ◽  
AWALUDDIN SARAGIH
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Body Weight ◽  
Treatment Group ◽  
Control Group ◽  
Model Assessment ◽  
Anti Inflammatory

Objective: This study aimed to determine whether the antidiabetic effects of puguntano (Curanga fel-terrae [Lour.]) extract involve anti-inflammatory effects mediated through adiponectin receptors (AdipoRs). Methods: Type 2 diabetes mellitus (T2DM) Wistar rats were induced by a combination of high-fat diet for 5 weeks and injection small dose streptozotocin 30 mg/kg bw/rat. This study was conducted in 48 T2DM rats, which were randomly assigned into two weight-matched groups (n=24, each). Only the treatment group received 0.2 mg/g bw of puguntano extract suspension through oral for 10 days. The clinical characteristics of T2DM and AdipoR were assessed before and after the treatment period. Results: The treatment group demonstrated significantly lower body weight, fasting blood glucose, and homeostasis model assessment-insulin resistance (HOMA-IR) but higher AdipoR than the control group (all, p<0.001). Furthermore, there were also negative correlations between AdipoR to body weight and HOMA-IR (all, p<0.05). Conclusion: Our data suggest that puguntano could improve glucose metabolism and ameliorate insulin resistance and have anti-inflammatory effects mediated through AdipoR in T2DM.

Sign in / Sign up

Export Citation Format

Share Document