scholarly journals CODIS STR LOCI (CSF1PO, THOI, TPOX, vWA) GENETIC VARIATION ANALYSIS IN MADURESE

2017 ◽  
Vol 52 (1) ◽  
pp. 1
Author(s):  
Ahmad Yudianto ◽  
Agung Sosiawan ◽  
Nola Margaret

Endogamy continues to occur among the Madurese people in rural areas of the island of Madura, especially those areas of the smallest islands around the mainland of Madura. Endogamy as seen from a genetic standpoint will increase the frequency of homozygote genotypes. With regard to genetic variations, STRs of nuclear DNA and polymorphisms in mtDNA are frequently examined. Genetic variations in human undergo an evolutionary process through the accumulation of changes in DNA sequence, i.e. through the process of nucleotide substitutions that evolves in number with the directional development of lineage. So far, the genetic variations among the populations in Madura Island have not been known. The present study was an observational analytical research with the purpose of determining the genetic variations in STR CODIS in the populations of Madura Island. Results indicated that, based on loci alelle: CSF1PO, THOI, TPOX, and vWA, there was homozygote genotypes. The allele variations is not specific for Madurese ethnic but this variations may represent married model in Madurese ethnic. According to Mustama (2007), a gene pool is not only a collection of genes but a dynamic system organized and containing the past history of a population. Any genetic information has certain historical, anthropological and statistical aspects necessitating an interdisciplinary coordination and collaboration.

2017 ◽  
Vol 52 (2) ◽  
pp. 80
Author(s):  
Nilly Sulistyorini ◽  
Ahmad Yudianto ◽  
Nola Margaret

Endogamy continues to occur among the Madurese people in rural areas of the island of Madura, especially those areas of the smallest islands around the mainland of Madura. Endogamy as seen from a genetic standpoint will increase the frequency of homozygous genotypes. With regard to genetic variations, STRs of nuclear DNA and polymorphisms in mtDNA are frequently examined. Mitochondrial variations in the human undergo an evolutionary process through the accumulation of changes in DNA sequence, i.e. through the process of nucleotide substitutions that evolves in number with the directional development of lineage. So far, the genetic variations among the populations in Madura Island have not been known. The present study was an observational analytical research with the purpose of determining the genetic variations in the polymorphisms of 126-bp mtDNA D-Loop HV2 (nt: 34-159) in the populations of Madura Island. Results indicated that, based on the homology analysis with rCRS sequence, there were 9 variants consisting of two transition mutations, 6 transversion mutations, and one insertion mutation. This indicates that a transversion mutation had a higher probability than transition and insertion mutations. According to Mustama (2007), a gene pool is not only a collection of genes but a dynamic system organized and containing the past history of a population. Any genetic information has certain historical, anthropological and statistical aspects necessitating an interdisciplinary coordination and collaboration.


1877 ◽  
Vol 25 (171-178) ◽  

George Poulett Scrope. It is scarcely possible at the present day to realize the conditions of that intellectual “reign of terror” which prevailed at the commencement of the present century, as the consequence of the unreasoning prejudice and wild alarm excited by the early progress of geological inquiry. At that period, every attempt to explain the past history of the earth by a reference to the causes still in operation upon it was met, not by argument, but by charges of atheism against its propounder; and thus Hutton’s masterly fragment of a ‘Theory of the Earth,’ Playfair’s persuasive‘ Illustrations,’ and Hall’s records of accurate observation and ingenious experiment had come to be inscribed m a social Index Expurgatorius ,and for a while, indeed, might have seemed to be consigned to total oblivion. Equally injurious suspicions were aroused against the geologist who dared to make allusion to the important part which igneous forces have undoubtedly played in the formation of certain rocks; for the authority of Werner had acquired an almost sacred cha­racter; and “ Vulcanists ” and “ Huttonians ” were equally objects of aversion and contempt. To two men who have very recently—and within a few months of one another—passed away from our midst, science is indebted for boldly en­countering and successfully overcoming this storm of prejudice. Hutton and his friends lived a generation too soon ; and thus it was reserved tor Lyell and Scrope to carry out the task which the great Scotch philosopher had failed to accomplish, namely, the removal of geology from the domain of speculation to that of inductive science.


Arsitektura ◽  
2017 ◽  
Vol 15 (1) ◽  
pp. 67
Author(s):  
Nurul Widowati ◽  
Winny Astuti ◽  
Murtanti Jani Rahayu

<div><p><em>Surakarta is a city that has the potential of the river. But in the process, these rivers suffered environmental degradation as a function instead of the banks into slums and squatter, and functions of rivers that serve as places of waste disposal. Government’s city of Surakarta has done various setup area of the river. One of the targeted structuring Pepe-River is often known by the name Kali Pepe. Kali Pepe is the river which has the most strategic location because it divides the centre of city and the river has a past history of Surakarta. Kali Pepe is the witness of history where culture and trade activities in the rapidly growing city of Surakarta in the past with the ecological function and physical function as transportation trade.Setuping Kali Pepe, according to the Mayor of Surakarta, is directed to serve as recreation/tourism area. Since the Surakarta Mayor initiated the year 2015 that Kali Pepe as a tourist area. The initiated moves the government and society in order to more actively participate in developing the area into a tourist area. This research would like to know how the readiness level of the Kali Pepe area to be developed as a tourist area-based streams. The components of preparedness were seen from aspect of attractions or natural tourist attraction, artificial attractions, acessesiblity, institutional, infrastructure supporting tourism, and the behavior of the flooding of the river. This research is quantitative research in methods of scoring analysis. The result of this research has shown that Kali Pepe less readiness to be developed as a tourist area-based stream. Aspects of accessibility and infrastructure supporting tourism were an aspect which has a readiness. But for this aspect of the attraction, institutional and river flooding behavior is still in the stage of less readiness.</em></p><p> </p><p><strong><em>Keywords:</em></strong><em> readiness, tourist areas, river tours</em></p></div>


PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261460
Author(s):  
Shabnam Iezadi ◽  
Kamal Gholipour ◽  
Ahmad Khanijahani ◽  
Mahasti Alizadeh ◽  
Bahram Samadirad ◽  
...  

Background Domestic violence (DV) is a universal issue and an important public health priority. Establishing a DV Registry System (DVRS) can help to systematically integrate data from several sources and provide valid and reliable information on the scope and severity of harms. The main objective of this study was to develop, validate, and pilot-test a minimum datasheet for a DVRS to register DV victims in medical facilities. Materials and methods This study was conducted in two main phases. Phase one includes developing the datasheet for registration of DV in the DVRS. In phase two, the datasheet designed in the previous step was used in a pilot implementation of the DVRS for 12 months to find practical challenges. The preliminary datasheet was first developed using information on similar registry programs and guidelines of the World Health Organization (WHO) and then reviewed by four expert panels. Through a two-round Delphi technique, experts evaluated the instrument using the Content Validity Index (CVI) and Content Validity Ratio (CVR). The consistency of the responses was evaluated by test-retest analysis. Finally, two physicians in two forensic medical clinics registered the victims of physical and/or sexual violence perpetrated by a family member. Results Preliminary datasheet consisted of 31 items. In the first round of Delphi, fifteen items had good content validity (I-CVI and CVR) and were kept, and seven items were moved to the next round. Also, in the first round of Delphi, experts suggested adding three items, including history of the violence, custody of the child, and custody of the elderly. All items evaluated in the second round were kept due to good CVR and CVI scores. As a result of Test-retest correlation coefficients for self-reprted items, two items including perpetrator’s alcohol and drug use status were excluded (r(30) = +.43, and +.38, p< .01, two-tailed, respectively). Finally, 24 items were included in the datasheet including 15 items for individuals’ characteristics (victims’ characteristics and perpetrators’ characteristics), eight items for incidents’ characteristics, and one item for past history of violence experience. A total of 369 cases were registered from September 23, 2019, to July 21, 2020. The majority of the reported cases were female (82%) and were 19–40 years old. No physical and/or sexual violence was reported from rural areas, which calls upon researchers to explore how services for detecting and treating the victims can be made accessible to these areas. Conclusion DVRS can show trends in DV by age, sex, the context of the violence, and incidence characteristics at every point in time. This is particularly valuable in planning and prioritizing research areas and interventions for DV prevention. Additionally, DVRS can be linked to other disease registry programs which can contribute to continuity and coordination of care, and major research in the future. Although a DVRS can be a promising initiative in identifying the areas in need of urgent interventions, there is no guarantee for its proper implementation due to limited resources and other challenges.


Kebudayaan ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 27-42
Author(s):  
I Made Sutaba

Archaeological researches in Indonesia have discovered a number of various historical and archaeological artifacts that belong to cultural heritage. As historical evidences, this cultural heritage is an important source of the plural information and messages of the past life of our society. It is remarkable that this cultural heritage has some problems for example problem of typology, function, meanings, and the other for the society. Studying the problems, it is interesting to do research on its function as a teller of the past history that contained various aspects of the life of our society that not yet studied until today. By learning the problems, this research goal is to find the answer of the problems. To reach this goal, we do this research gradually by collecting data through literature study and field observation along with interviews. The next step is analysis carried out through methods of typology analysis, contextual, functional analysis, ethno archaeological and ethno historical approach. Finally the result showed that the function of our cultural heritage is as teller of the many-sided aspects of the past history of our artifacts such as technological aspects, social, and religious aspects but it is impossible to get full completed information due to some reasons. Keywords: archaeological and historical artifacts, cultural heritages, teller of the past.  AbstrakPenyelidikan arkeologi di Indonesia sudah berhasil menemukan artefak sejarah dan arkeologi yang beraneka ragam, yang tergolong sebagai warisan budaya. Sebagai bukti-bukti sejarah, warisan budaya ini adalah sumber informasi dan pesan-pesan kehidupan masyarakat masa lalu yang bersifat pluralistik. Menarik perhatian, bahwa warisan budaya ini mempunyai permasalahan yaitu, permasalahan tipologi, fungsi dan makna dalam kehidupan masyarakat. Mempelajari masalah ini, sangat menarik untuk melakukan penelitian mengenai fungsinya sebagai penutur sejarah masa silam, yang mengandung aneka ragam, aspek kehidupan masyarakat, yang belum dikaji sampai sekarang. Dengan mencermati permasalahan ini, maka tujuan penelitian ini, adalah untuk meneliti permasalahan tadi. Untuk mencapai tujuan ini, penulis melakukan penelitian secara bertahap melalui pengumpulan data dengan metode kajian pustaka dan observasi lapangan yang disertai dengan wawancara. Langkah selanjutnya, adalah melakukan analisis dengan analisis tipologi, kontekstual, analisis fungsional, pendekatan etnoarkeologi dan etnohistori. Hasil penelitian ini menunjukkan bahwa cagar budaya itu berfungsi sebagai penutur kehidupan masa silam yang mengandung aspek yang bersfiat jamak, adalah aspek teknologi, sosial dan religi, tetapi tidak mungkin untuk mendapat informasi yang lengkap karena berbagai faktor.Kata kunci: peninggalan sejarah dan purbakala, warisan budaya, penutur masa silam.


2016 ◽  
pp. 24 ◽  
Author(s):  
Malini Suchak ◽  
Michael Piombino ◽  
Kalina Bracco

Colony housing of cats allows shelters to maximize the number of cats housed in limited space. Most research on colony-housed cats examines stress in relation to group size or enclosure size.  While this is important for evaluating welfare, it is equally important to understand how cats are interacting socially in these colonies. We observed 259 adult cats housed in groups of two to eight individuals. Scan samples were used to assess how frequently individual cats were in close proximity to other cats. These data were used to measure individual differences in sociability and patterns of proximity to certain partners. We used information about the past history of the cat, which was collected upon admission to the shelter to identify predictors of time spent in proximity. There was a high degree of inter-individual variability in sociability. Strays tended to spend less time in proximity to other cats, and this effect was most pronounced in females.However, none of the information collected upon admission predicted patterns of proximity to certain partners, or which cats spent time in association witheach other. Future studies should explore the implications of differences in sociability by associating observations of social behavior and stress behaviors.


2013 ◽  
Vol 23 ◽  
pp. 451-453 ◽  
Author(s):  
COSTANTINO SIGISMONDI

The role of Venus and Mercury transits is crucial to know the past history of the solar diameter. Through the W parameter, the logarithmic derivative of the radius with respect to the luminosity, the past values of the solar luminosity can be recovered. The black drop phenomenon affects the evaluation of the instants of internal and external contacts between the planetary disk and the solar limb. With these observed instants compared with the ephemerides the value of the solar diameter is recovered. The black drop and seeing effects are overcome with two fitting circles, to Venus and to the Sun, drawn in the undistorted part of the image. The corrections of ephemerides due to the atmospheric refraction will also be taken into account. The forthcoming transit of Venus will allow an accuracy on the diameter of the Sun better than 0.01 arcsec, with good images of the ingress and of the egress taken each second. Chinese solar observatories are in the optimal conditions to obtain valuable data for the measurement of the solar diameter with the Venus transit of 5/6 June 2012 with an unprecedented accuracy, and with absolute calibration given by the ephemerides.


2020 ◽  
Vol 73 (11) ◽  
pp. 2416-2420
Author(s):  
Olena О. Taranovska ◽  
Volodymyr К. Likhachov ◽  
Ludmyla М. Dobrovolska ◽  
Oleg G. Makarov ◽  
Yanina V. Shymanska

The aim: To determine the serum FAMG in the I and II trimester of pregnancy in women with a past history of chronic endometritis, and to clarify its impact on the development of pathology of pregnancy. Materials and methods: The level of FAMG was determined at 6-8 and 16-18 weeks of gestation in 135 pregnant women with a past history of chronic endometritis, who received treatment of chronic endometritis at the stage of pregravid preparation and 168 women who became pregnant without its prior treatment. The dependence of the development of pre-eclampsia on the level of FAMG at the early stages of pregnancy has been evaluated. Results: At 6-8 weeks of pregnancy, the level of FAMG in women with a past history of chronic endometritis was 20.6% lower (122.4 ± 7.6 ng/ml) compared to the control group. In FAMG of 90.3 ± 4.3 ng/ml at 6-8 weeks of gestation, spontaneous abortion occurred in 100% of cases within the next 2 weeks. FAMG lower than 122,1 ± 3,0 ng/ml can be the predisposing factor for the development of pre-eclampsia. Conclusions: Reduced FAMG in the beginning of pregnancy in women with untreated chronic endometritis in the past history increases the incidence of miscarriages at the early stages by 2.6 times, and by 1.8 times the probability of preeclampsia development. Treatment of chronic endometritis at the stage of pregravid preparation promotes the increase of FAMG by 24,6% compared to untreated women that reduces the probability of complications during the subsequent course of pregnancy.


2018 ◽  
Vol 612 ◽  
pp. A112 ◽  
Author(s):  
T. Encrenaz ◽  
C. DeWitt ◽  
M. J. Richter ◽  
T. K. Greathouse ◽  
T. Fouchet ◽  
...  

The global D/H ratio on Mars is an important measurement for understanding the past history of water on Mars; locally, through condensation and sublimation processes, it is a possible tracer of the sources and sinks of water vapor on Mars. Measuring D/H as a function of longitude, latitude and season is necessary for determining the present averaged value of D/H on Mars. Following an earlier measurement in April 2014, we used the Echelon Cross Echelle Spectrograph (EXES) instrument on board the Stratospheric Observatory for Infrared Astronomy (SOFIA) facility to map D/H on Mars on two occasions, on March 24, 2016 (Ls = 127°), and January 24, 2017 (Ls = 304°), by measuring simultaneously the abundances of H2O and HDO in the 1383–1391 cm−1 range (7.2 μm). The D/H disk-integrated values are 4.0 (+0.8, −0.6) × Vienna Standard Mean Ocean Water (VSMOW) and 4.5 (+0.7, −0.6) × VSMOW, respectively, in agreement with our earlier result. The main result of this study is that there is no evidence of strong local variations in the D/H ratio nor for seasonal variations in the global D/H ratio between northern summer and southern summer.


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