scholarly journals EFFECTS OF BLUE LIGHT EMITTING DIODE (LED) AND DOXYCYCLINE TO SEBACEOUS GLAND IN ACNE VULGARIS

2017 ◽  
Vol 53 (4) ◽  
pp. 272
Author(s):  
M Yulianto Listiawan ◽  
Cita Rosita Sigit Prakoeswa ◽  
Dhyah Aksarani Handamari ◽  
Regitta Indira
Keyword(s):  
Combination Therapy ◽  
Blue Light ◽  
Propionibacterium Acnes ◽  
Light Emitting Diode ◽  
Acne Vulgaris ◽  
Sebaceous Glands ◽  
Pilosebaceous Unit ◽  
Light Emitting ◽  
Severe Acne ◽  
Sebum Production

Acne vulgaris (AV) is an inflammation of pilosebaceous unit especially in young adult. The pathophysiology is the elevation of sebum production, keratinization of abnormal pilocebaseous follicles, and inflammation caused by immune response to Propionibacterium acnes. Therapy combination of oral antibiotics (doxycycline) and physical therapy (blue light) in moderate-severe acne is one option to reduce antibiotic resistance. Doxycycline is a commonly antibiotic used. The effects of photosensitive can increase the penetration of blue light by sebaceous glands. There was a total decrease in sebum and clinical improvement of combination therapy of blue light and doxycycline in seven patients. The combination therapy has been shown to improve its therapeutic effect, but more clinical trials are needed to prove the effectiveness of blue light with doxycycline than without blue light.

scholarly journals A review of phytotherapy of Acne vulgaris

2009 ◽  
Vol 55 ◽  
pp. 3-22 ◽  
Author(s):  
Marija Glavas Dodov ◽  
Svetlana Kulevanova
Keyword(s):  
Combination Therapy ◽  
Staphylococcus Epidermidis ◽  
Propionibacterium Acnes ◽  
Scientific Evidence ◽  
Acne Vulgaris ◽  
Treatment Options ◽  
Common Condition ◽  
Pilosebaceous Unit ◽  
Research Support ◽  
Sebum Production

Acne vulgaris (acne) is a cutaneous pleomorphic disorder of the pilosebaceous unit involving abnormalities in sebum production and is characterized by both inflammatory (papules, pustules and nodules) and non-inflammatory (comedones, open and closed) lesions. Propionibacterium acnes and Staphylococcus epidermidis are common pus-forming microbes responsible for the development of various forms of acne. This disease remains a common condition in industrialized societies, with many mainstream treatment options available. There are many acne products on the market, and making an appropriate selection can be daunting. Common therapies that are used for the treatment of acne include topical, systemic, hormonal, herbal and combination therapy. Topically used agents are benzoyl peroxide, antibiotics and retinoid. Systemically used agents are antibiotics and isotretinoin. However, all such treatments carry risks and none is completely satisfactory. Natural alternatives are gaining greater research support, and have much to offer clinically in this disorder. This review focuses primarily on herbal treatments for acne that show scientific evidence of clinical efficacy, as well as the more common herbs shown to be useful in the treatment of this dermatologic disorder.

scholarly journals The Role of Digital Fluorescence in Acne Vulgaris: Correlation of Ultraviolet Red Fluorescence with the Severity of Acne Vulgaris

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Imam Budi Putra ◽  
Nelva K. Jusuf ◽  
Nani Kumala Dewi
Keyword(s):  
Propionibacterium Acnes ◽  
Acne Vulgaris ◽  
Severe Acne ◽  
Red Fluorescence ◽  
Acne Lesion ◽  
Percentage Area ◽  
Sebum Production ◽  
Spearman Test

Background. Colonization of Propionibacterium acnes (P. acnes) and increased sebum production play important roles in the pathogenesis of acne vulgaris. Severity of acne vulgaris correlates with the lesion counts both noninflammatory and inflammatory. Digital fluorescence has been found useful in pathogenesis investigation and treatment evaluation. Ultraviolet-induced red fluorescence (UVRF) was found to be correlated with sebum and porphyrin production that can be synthesized by P. acnes. Therefore, UVRF assessment could be useful for the evaluation of the degree and extent of acne vulgaris. Objective. To evaluate the correlation of UVRF with the severity of acne vulgaris using the digital fluorescence tool. Methods. Forty-five patients were diagnosed with mild-to-severe acne vulgaris according to Lehmann classification. Lesion counts both noninflammatory and inflammatory and UVRF assessment using Visiopor PP34 camera were done to all participants in 5 divided facial areas (forehead, nose, right and left cheeks, and chin). Clinical assessment for each patient was done by 3 dermatologists. Determination of correlation between UVRF with acne lesion counts was done using Pearson test and with acne severity using Spearman test. Results. From 45 participants, majority had moderate acne (64.4%), followed by severe (24.5%) and mild acne (11.1%). Mean number of UVRF spots was 39.98 ± 11.45 and percentage area covered with UVRF was 4.39 ± 1.72. There was no correlation found between acne lesion counts, including noninflammatory and inflammatory with the number and percentage area covered with UVRF spots. Severity grade of acne vulgaris was found to be uncorrelated with the number of UVRF spots (r = 0.27, p=0.073) and percentage area covered with UVRF spots (r = 0.173, p=0.256). Conclusion. The severity of acne vulgaris has no correlation with spot counts and percentage area covered with UVRF. Digital fluorescence might be helpful in investigating further of the interrelated pathogenesis factors of acne.

scholarly journals In vitro and in vivo Efficacy of New Blue Light Emitting Diode Phototherapy Compared to Conventional Halogen Quartz Phototherapy for Neonatal Jaundice

2005 ◽  
Vol 20 (1) ◽  
pp. 61 ◽  
Author(s):  
Yun Sil Chang ◽  
Jong Hee Hwang ◽  
Hyuk Nam Kwon ◽  
Chang Won Choi ◽  
Sun Young Ko ◽  
...  
Keyword(s):  
Blue Light ◽  
Neonatal Jaundice ◽  
Light Emitting Diode ◽  
In Vivo Efficacy ◽  
Light Emitting

scholarly journals Operando direct observation of spin-states and charge-trappings of blue light-emitting-diode materials in thin-film devices

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Fumiya Osawa ◽  
Kazuhiro Marumoto
Keyword(s):  
Blue Light ◽  
High Performance ◽  
Density Functional ◽  
Light Emitting Diode ◽  
Green Light ◽  
Spin States ◽  
Light Emitting ◽  
Full Color ◽  
Color Displays ◽  
Materials Used

Abstract Spin-states and charge-trappings in blue organic light-emitting diodes (OLEDs) are important issues for developing high-device-performance application such as full-color displays and white illumination. However, they have not yet been completely clarified because of the lack of a study from a microscopic viewpoint. Here, we report operando electron spin resonance (ESR) spectroscopy to investigate the spin-states and charge-trappings in organic semiconductor materials used for blue OLEDs such as a blue light-emitting material 1-bis(2-naphthyl)anthracene (ADN) using metal–insulator–semiconductor (MIS) diodes, hole or electron only devices, and blue OLEDs from the microscopic viewpoint. We have clarified spin-states of electrically accumulated holes and electrons and their charge-trappings in the MIS diodes at the molecular level by directly observing their electrically-induced ESR signals; the spin-states are well reproduced by density functional theory. In contrast to a green light-emitting material, the ADN radical anions largely accumulate in the film, which will cause the large degradation of the molecule and devices. The result will give deeper understanding of blue OLEDs and be useful for developing high-performance and durable devices.

Optimization and evaluation of a blue light photoinitiating system for textile inkjet printing

2018 ◽  
Vol 89 (10) ◽  
pp. 1964-1974
Author(s):  
Yi Huang ◽  
Guangdong Sun ◽  
Yating Ji ◽  
Dapeng Li ◽  
Qinguo Fan ◽  
...  
Keyword(s):  
Blue Light ◽  
Light Emitting Diode ◽  
Absorption Efficiency ◽  
Polymerization Rate ◽  
Nozzle Clogging ◽  
Light Emitting ◽  
Custom Made ◽  
Light Curing ◽  
Set Up ◽  
Pigment Ink

A blue light curing process was developed to solve the nozzle clogging challenge commonly encountered in conventional textile pigment printing, by using camphorquinone (CQ) and ethyl-4-dimethylaminobenzoate (EDMAB) as a photoinitiator combination and substituting oligomers and monomers for a polymeric binder. High light absorption efficiency was insured by closely matching the spectrum of the photoinitiator with a custom-made blue light light-emitting diode set-up. Kinetic analyses of such a CQ/EDMAB system indicated that the maximum polymerization rate of the monomer was proportional to [PI]0.5 and [I0]0.5, while excessive high photoinitiator concentration (>1 wt%) will decrease the polymerization rate because of the “filter effect.” With optimized blue light curable pigment ink formula and irradiation conditions, the photocurable pigment printed fabrics exhibited uniform and vibrant colors, clear outlines, and excellent wet and dry rubbing fastness of grades 4 and 4–5, respectively.

scholarly journals Homogeneous ZnO nanowire arrays p-n junction for blue light-emitting diode applications

2019 ◽  
Vol 27 (16) ◽  
pp. A1207 ◽  
Author(s):  
Mingming Su ◽  
Tanglei Zhang ◽  
Jun Su ◽  
Zhao Wang ◽  
Yongming Hu ◽  
...  
Keyword(s):  
Blue Light ◽  
Light Emitting Diode ◽  
Nanowire Arrays ◽  
Zno Nanowire ◽  
Light Emitting ◽  
Zno Nanowire Arrays

scholarly journals Hubungan antara Mencuci Wajah dengan Kejadian Akne Vulgaris pada Remaja Laki-laki di Manado

e-CliniC ◽  
2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Fifin R. T. Sole ◽  
Pieter L. Suling ◽  
Tara S. Kairupan
Keyword(s):  
Propionibacterium Acnes ◽  
Acne Vulgaris ◽  
Adolescent Males ◽  
Personal Hygiene ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Severe Acne ◽  
Akne Vulgaris ◽  
The Relationship

Abstract: Acne vulgaris is a chronic skin condition involving inflammation of the pilosebaceous follicle. The highest prevalence of acne vulgaris is at the age of 16-17 years. Pathogenic factors contributing to the development of acne vulgaris include increased sebum production, pilosebaceous follicular blockage, and increased colonization of Propionibacterium acnes. Personal hygiene is suggested as an important factor that needs to be maintained in acne prevention. Males tend to lack of awareness to seek information and health services in dealing with acne problems. This study was aimed to evaluate the relationship between facial washing and the incidence of acne vulgaris in adolescent males in Manado. This was an analytical and observational study using a cross-sectional design. Subjects were male students of 3rd grade at SMA Negeri 9 Manado, aged 16-19 years old, and met the inclusion and exclusion criteria, with a total number of 95 students. Subjects who washed their faces 2-3 times a day were 38 students (40%) while those who washed their faces less than twice or more than thrice a day were 57 students (60%). Subjects with no or mild acne vulgaris were 39 students (41.1%), while those with moderate to severe acne vulgaris were 56 students (58.9%). The chi-square showed a p-value of 0.004 for the relationship between the frequency of facial washing and the incidence of acne vulgaris. In conclusion, there was a significant relationship between facial washing and the incidence of acne vulgaris in adolescent males in Manado.Keywords: facial washing, acne vulgaris Abstrak: Akne vulgaris merupakan peradangan kronis folikel pilosebasea dengan prevalensi tertinggi pada usia 16-17 tahun. Faktor yang memengaruhi terjadinya akne vulgaris antara lain peningkatan produksi sebum, penyumbatan folikel pilosebasea, dan peningkatan kolonisasi bakteri Propionibacterium acnes. Kebersihan diri merupakan faktor penting yang perlu dijaga sebagai salah satu usaha untuk mencegah timbulnya akne. Laki-laki cenderung kurang memiliki kesadaran untuk mencari informasi dan pelayanan kesehatan dalam menangani masalah akne. Penelitian ini bertujuan untuk menilai hubungan antara mencuci wajah dengan kejadian akne vulgaris pada remaja laki-laki di Manado. Jenis penelitian ialah observasional analitik dengan desain potong lintang. Subjek penelitian ialah siswa laki-laki kelas 3 di SMA Negeri 9 Manado, usia 16-19 tahun, dan memenuhi kriteria inklusi dan eksklusi, dengan jumlah total 95 siswa. Subjek yang mencuci wajah 2-3 kali sehari sebanyak 38 siswa (40%) sedangkan yang mencuci wajah kurang dari 2 kali atau lebih dari 3 kali sehari sebanyak 57 siswa (60%). Subjek tanpa akne vulgaris atau akne derajat ringan sebanyak 39 siswa (41,1%) sedangkan yang dengan akne vulgaris derajat sedang sampai berat sebanyak 56 siswa (58,9%). Uji chi-square memperlihatkan nilai p=0.004 terhadap hubungan antara frekuensi mencuci wajah dengan kejadian akne vulgaris. Simpulan penelitian ini ialah terdapat hubungan bermakna antara mencuci wajah dengan kejadian akne vulgaris pada remaja laki-laki di Manado.Kata kunci: mencuci wajah, akne vulgaris

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