scholarly journals UJI SENSITIVITAS BAKTERI PENYEBAB INFEKSI SALURAN KEMIH PADA PASIEN DIABETES MELITUS TERHADAP SEFTRIAKSON, LEVOFLOKSASIN, DAN GENTAMISIN

2016 ◽  
Vol 12 (2) ◽  
pp. 205
Author(s):  
Nova Octavianty Rachman ◽  
Muhamad Darwin Prenggono ◽  
Lia Yuli Budiarti

Abstract: Urinary Tract Infection (UTI) is a general term that indicates the presences or propagation of microorganism in urine. The urinary tract infection is a very common condition that occurs in both women and men of all ages. Diabetes Mellitus (DM) can lead to the development of bacteriuria. Bacterial resistance to antibiotics prolongs the UTI recover. The aim of this research was to find out bacterial sensitivity urinary tract infection in patients diabetes mellitus to selected antibiotic during July-September 2015. It was a descriptional study with cross-sectional. The subject of this research is all patients diabetes mellitus with urinary tract infection in internal medicine wards Ulin General Hospital Banjarmasin. The sampling technique in this research was a total sampling. The sensitivity test to antibiotic test in the research used Kirby Bauer method and analyzed according to CLSI 2013 standard.This type of bacteria found in this research are Escherichia coli, Pseudomonas aerugenosa, Staphylococcus epidermidis, and Staphylococcus aureus. The sensitivity test result the percentage type of bacteria are sensitive to ceftriaxone 73%, levofloxaxin 84,6%, and gentamicin 73%. The conclution is that most sensitive antibiotic is levofloxaxin (84,6%) Keywords: diabetes mellitus (DM), urinary tract infection (UTI), ceftriaxone, levofloxaxin, gentamicin. Abstrak: Infeksi Saluran Kemih (ISK) didefinisikan sebagai adanya infeksi bakteri dalam urin yang ditandai dengan bakteriuria bermakna. Infeksi saluran kemih merupakan kondisi yang sangat umum terjadi baik pada wanita maupun pria pada semua usia. Diabetes Melitus (DM) dapat menyebabkan perkembangan bakteriuria. Resistensi bakteri terhadap antibiotik menyebabkan lamanya penyembuhan dari ISK. Penelitian ini bertujuan mengetahui sensitivitas bakteri penyebab ISK pada pasien DM terhadap antibiotik terpilih periode Juli-September 2015. Penelitian ini merupakan penelitian deskriptif dengan pendekatan Cross Sectional. Subjek penelitian ini adalah seluruh pasien DM dengan ISK Rawat Inap di Bangsal Penyakit Dalam RSUD Ulin Banjarmasin. Teknik pengambilan sampel pada penelitian ini adalah Total Sampling. Uji sensitivitas bakteriuria terhadap antibiotik uji pada penelitian ini menggunakan metode Kirby-Bauer dan dianalisis secara deskriptif sesuai dengan standar CLSI 2013. Jenis bakteri yang ditemukan pada penelitian ini adalah Escherichia coli, Pseudomonas aerugenosa, Staphylococcus epidermidis, Staphylococcus aureus. Hasil uji sensitivitas menunjukkan bahwa presentase jenis bakteri yang sensitif terhadap Seftriakson 73%, Levofloksasin 84,6%, dan Gentamisin 73%. Persentase isolat bakteri yang resisten terhadap Seftriakson 15,3%, Levofloksasin 3,8%, dan Gentamisin 3,8%. Kesimpulan antibiotik yang paling sensitif terhadap bakteri penyebab ISK pada penilitian ini adalah Levofloksasin (84,6%). Kata-Kata kunci: diabetes melitus (DM), infeksi saluran kemih (ISK), seftriaxon, levofloksasin, gentamisin

2020 ◽  
Vol 58 (221) ◽  
Author(s):  
Arun Giri ◽  
Raju Kafle ◽  
Ganesh Kumar` Singh ◽  
Niraj Niraula

Introduction: Urinary tract infection is one of the commonest causes of childhood morbidity. Earlydiagnosis and appropriate choice of antimicrobials is essential. Hence, this study aims to identify theprevalence of Escherichia coli in childhood urinary tract infections. Methods: This was a hospital based descriptive cross-sectional study conducted in Nobel MedicalCollege, Biratnagar over a period of one year. A total of 163 cases aged 1-15 years were included andclinical profile, laboratory reports including bacterial isolates in urine cultures and their sensitivitypatterns were documented. Results: The prevalence of Escherichia coli is 45 (53.57%) C.I. Escherichia coli was the most commonorganism isolated in bacterial cultures followed by Klebsiella 12 (14.29%), Enterococcus 10 (11.90%).Urinary tract infection was common among females with male: female ratio of 1:2.3. Fever 152(93.2%) and abdominal pain 113 (69.3%) were the most common presenting symptoms. Escherichiacoli was found most sensitive to Nitrofurantoin 43 (95.5%) followed by Ciprofloxacin 41 (91.1%) andAmikacin 40 (88.8%). Conclusions: Urinary tract infections in childhood require prompt attention and treatment to preventsignificant morbidity and mortality. From this study it can be concluded that Escherichia coli is oneof the most common isolates in urine culture and Aminoglycosides and Fluoroquinolones can beaccepted as empirical treatment regimens for childhood Urinary tract infections.


2021 ◽  
Vol 11 (Number 1) ◽  
pp. 26-32
Author(s):  
Chowdhury MJ ◽  
Faruque CMO ◽  
Noor J ◽  
Rouf CM ◽  
Hossain MM ◽  
...  

Background: Urinary tract infection (UTI) has become the most frequent bacterial infections worldwide. It is well established that Escherichia coli is the predominant cause of UTI. The aim of our study was to evaluate the rates of resistance to fluroquinolone and third generation cephalosporin among the patients with UTI due to E.Coli and to assess the potential correlation between both trends. Methods: The study was a cross sectional observational study conducted at the Department of Pharmacology and Therapeutics in collaboration with Department of Microbiology of Sylhet Women’s Medical College and Hospital from 1st July 2019 to 30th June 2020. Results: A total of 246 urine samples were collected from patients with UTI followed by isolation and identification of E.coli strains. Antibiotic sensitivity and resistance analysis was performed by the disc diffusion method employing multiple antibiotic discs. The sensitivity was monitored by zone of inhibition around the disc. Overall rates of resistance to fluroquinolone and third generation cephalosporin were 70.31% and 65.10% respectively. The rates of co-resistance to both fluroquinolone and third generation cephalosporin was 53.13%. Conclusion: Our study suggests that fluroquinolone should be reserved and third generation cephalosporin should be used with caution among patients with E.coli.


Author(s):  
Vinoth M. ◽  
Prabagaravarthanan R. ◽  
Bhaskar M.

Background: Catheter-associated urinary tract infection (CAUTI) is an important cause of morbidity and mortality in Indian subjects, affecting all age groups. Bacteriuria orcandiduria is almost inevitable in nearly half of the patients who require an indwelling urinary catheter for more than 5 days. The objective of this study was to find the prevalence of CAUTI infection and to determine their antibiotic profileMethods: The present cross-sectional study included 50 patients admitted to medicine and surgery wards in our hospital. The urine from catheter is collected from each patient and subjected to culture and antibiotic susceptibility testing.Results: The prevalence of catheter associated urinary tract infection in our hospital is about 20% and asymptomatic bacterial colonization is 50% which is nearequal to Danchaivijitr S et al study. The common pathogens found in this study are Escherichia coli (22%), Klebsiella (18%), Enterobacter (8%), Staph. aureus (6%) which include MRSA (4%), Pseudomonas (6%), Enterococcus (4%), Candida sps. (4%) Andproteus (2%).Conclusions: CAUTI has low prevalence 20% and asymptomatic colonisation 50% in our hospital with common pathogen being Escherichia coli. It is one of the important notable pathogen causing nosocomial infection among admitted patients. The patients present mainly as asymptomatic bacterial colonisation and risk of CAUTI increases with longer duration of catheterisation. All patients those who had catheter for more than 6 days, aged 60 and above, should be checked for UTI symptoms. And their urine should be cultured regularly in order to diagnose and prevent CAUTI and its complications which are very dangerous and difficult to treat.


2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Taqi Mohammed Jwad Taher ◽  
Firas Turki Rashed Sarray ◽  
Ammar Shimal Shwekh ◽  
Tariq Kuraidi Mareedh ◽  
Hasanain Faisal Ghazi

  Introduction: Urinary tract infection is a very prevalent disease among humans and it is highly presented among patients with diabetes mellitus. The main aim of the current study was to find out the commonest bacterial organisms causing urinary tract infection among a sample of diabetic and non-diabetic patients in Al-Kut city, Iraq. Methods: A cross-sectional study was conducted among 100 conveniently sampled patients suffering from urinary tract infections and attending Al-Karama Teaching hospital laboratory for urine culture between October and December 2019 were included in the study. The patients were consented to answer a special questionnaire containing data like patients' age, gender, and disease status (diabetic or non-diabetic). Results: From the 100 participated patients there were 29 (29%) with diabetes and the remaining 71(71%) from the sample were non-diabetics. The females represent the majority of the sample (67%) while males represented only (33%). The most common identified bacteria from this sample were Staphylococcus aureus (48%), Escherichia coli (24%), Klebsiella pneumoniae (17%), Enterococcus species (5%), and Pseudomonas aeruginosa (2%). The study result shows a significant association of being diabetic or not >0.001, 0.038with age and gender of the patients (p-value) respectively. While this association was non-significant when considering the type of bacteria between the two . While this association was non-significant when considering the groups (P-value=0.056).type of bacteria between the two groups (P-value=0.056). Conclusion: The urinary tract infection is frequently presented among young non-diabetic females and near half of the urine cultures showed the Staphylococcus aureus bacteria as the commonest cause of infection among them.


2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Jemmy C. Sie

Abstract: One of the most common nosocomial infection is urinary tract infection (UTI); 80% of cases are associated with the use of urethral catheters. The most common pathogens are Escherichia coli, Enterococcus, Klebsiella, Pseudomonas, Proteus, and Enterobacter species. Bacteria patterns could change from time to time and from area to area. This study aimed to obtain the bacteria pattern in urine of patients using urethral catheter.This was a descriptive prospective study. There were 20 urine samples from November 2013 until January 2014 in IRINA RSUP Prof Dr RD Kandous Manado. The results showed that age >60 years was the most common age group (41.8%). Males (84.9%) were predominantly affected in this study. Staphylococcus epidermidis was found in 20% of samples, followed by several other bacteria. Conclusion: The most affected age group using urethral catheter with bacteriuria was over 60 years, more frequent in males, and the most common pathogen was Staphylococcus epidermidis.Keywords: bacteria, bacteria pattern, urinary tract infection, nosocomial infection, urethral catheterAbstrak: Salah satu infeksi nosokomial yang sering terjadi adalah infeksi saluran kemih (ISK), 80% kasus ISK diasosiasikan dengan penggunaan kateter uretra. Patogen yang paling sering ditemukan adalah Escherichia coli, Enterococcus, Klebsiella, Pseudomonas, Proteus, dan Enterobacter. Pola bakteri dapat berbeda dari waktu ke waktu dan dari daerah ke daerah. Penelitian ini bertujuan untuk mengetahui pola bakteri pada urin pasien yang menggunakan kateter.Penelitian ini menggunakan desain penelitian deskriptif prospektif pada 20 sampel urin selama bulan November 2013 hingga Januari 2014 di instalasi rawat inap RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian memperlihatkan umur 61-70 tahun merupakan insidensi tertinggi. Jumlah sampel laki-laki dengan bakteriuria lebih banyak dibandingkan perempuan. Simpulan: Kelompok umur tersering yang menggunakan kateter uretra dengan bakteriuria ialah umur di atas 60 tahun, lebih sering pada laki-laki, dan bakteri yang paling banyak ditemukan Staphylococcus epidermidis.Kata kunci: bakteri, pola bakteri, infeksi saluran kemih, infeksi nosokomial, kateter uretra


2016 ◽  
Vol 8 (2) ◽  
Author(s):  
Valentine Umboh ◽  
Adrian Umboh

Abstrak: Infeksi saluran kencing (ISK)masih sering ditemukan pada anak-anak dan berperan dalam tingginya jumlah pasien yang dirawat di rumah sakit. Oleh karena itudibutuhkan diagnosis dan penanganan dini terhadap pasien ISK. Penelitian ini bertujuan untuk menentukan profil klinik dan laboratorik ISK pada pasien yang dirawat di Bagian Anak RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ini ialah retrospektif menggunakan data pasien dari Desember 2009 sampai Desember 2014. Hasil penelitian mendapatkan 65 pasien terdiagnosis ISK berusia 0-15 tahun terdiri dari 37 berjenis kelamin perempuan dan 27 berjenis kelamin laki-laki. Data rekam medik mengenai gambaran klinis dan hasil laboratorium memperlihatkan persentae tertinggi ialah demam (76,6%) diikuti mual dan muntah (26,6%), nyeri perut(17,2%), and diare (14,0%). Pada hasil urinalisisdidapatkan pH urin <6,5 (62,5%) dan pH urin 6,5-8,0 (27,5%). Kuman tersering dari hasil kultur urin ialah Proteus sp. (32,8%), Staphylococcus aureus (20,%), dan Escherichia coli (10,9%). Simpulan: Gambaran klinik dan laboratorik dari anak-anak dengan infeksi saluran kencing di RSUP Prof. Dr. R. D. Kandou Manado tidak berbeda bermakna dengan di negara maju dan di negara berkembang lainnya. Walaupun demikian hasil penelitian ini dapat membantu pertimbangan diagnosis dini pada pasien anak.Kata kunci: infeksi saluran kencing, kultur urin, demam, urinalisisAbstract: Urinary tract infection (UTI) is still common among children all over the world and cause a significant number of patient admission to the hospital. Keeping in view the high incidence of UTI in children with associated morbidity and mortality, it is imperative to diagnose and to treat the infection as early as possible. This study aimed to determine the clinical and laboratory profiles of UTI among patients admitted at Pediatric Ward Prof. Dr. R. D. Kandou Hospital Manado. This was a retrospective study. Clinical and laboratory presentation of the UTI patients were obtained from the medical records from December 2009 to December 2014. The results showed that there were 65 cases of UTI aged 0 to 15 years in this study consisted of 37 females and 27 males. Fever was the commonest clinical presentation (76.6%) followed by nausea and vomitting (26.6%), flank pain (17.2%), and diarrhea (14.0%). From the urinalysis it was found that the urine pHs were <6.5 (62.5%) and 6.5-8.0 (27.5%). Proteus sp. (32.8%), Staphylococcus aureus (20.3%), and Escherichia coli(10.9%) were the most common bacteria found in urinary culture. Conclusion: Clinical and laboratory profile of urinary tract infection in children at Pediatric Ward Prof. Dr. R. D. Kandou Hospital Manado was not significantly different from that of other developing and developed countries. Albeit, it willhelp us in confirming early diagnosis of urinary tract infection among pediatrics patients.Keywords: urinary tract infection, urine culture, fever, urinalysis


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