Prevalence of E. Coli in Urinary Tract Infection of Children Aged 1-15 Years in A Medical College of Eastern Nepal

Introduction: Urinary tract infection is one of the commonest causes of childhood morbidity. Earlydiagnosis and appropriate choice of antimicrobials is essential. Hence, this study aims to identify theprevalence of Escherichia coli in childhood urinary tract infections. Methods: This was a hospital based descriptive cross-sectional study conducted in Nobel MedicalCollege, Biratnagar over a period of one year. A total of 163 cases aged 1-15 years were included andclinical profile, laboratory reports including bacterial isolates in urine cultures and their sensitivitypatterns were documented. Results: The prevalence of Escherichia coli is 45 (53.57%) C.I. Escherichia coli was the most commonorganism isolated in bacterial cultures followed by Klebsiella 12 (14.29%), Enterococcus 10 (11.90%).Urinary tract infection was common among females with male: female ratio of 1:2.3. Fever 152(93.2%) and abdominal pain 113 (69.3%) were the most common presenting symptoms. Escherichiacoli was found most sensitive to Nitrofurantoin 43 (95.5%) followed by Ciprofloxacin 41 (91.1%) andAmikacin 40 (88.8%). Conclusions: Urinary tract infections in childhood require prompt attention and treatment to preventsignificant morbidity and mortality. From this study it can be concluded that Escherichia coli is oneof the most common isolates in urine culture and Aminoglycosides and Fluoroquinolones can beaccepted as empirical treatment regimens for childhood Urinary tract infections.

Download Full-text

The Prevalence of Bacterial Pathogens associated with Urinary Tract Infection (UTI) among Patients attending Kam Medical Consult Clinic, Uganda.

10.51168/sjhrafrica.v2i6.35 ◽

2021 ◽

Author(s):

◽

Gerald Turyatunga

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Bacterial Pathogens ◽

Clinical Signs ◽

Cross Sectional Study ◽

Cross Sectional ◽

Etiological Agents ◽

Tract Infections

Background: A urinary tract infection (UTIs) is a common type of infection caused by bacteria that travel up the urethra to the bladder. Globally, it is reported that 150 million people are diagnosed with a UTI annually, costing the world economy over 6 million US dollars in treatment and work loss. Studies conducted in the in-patients pediatric ward of Muhimbili Hospital in Tanzania and Mulago National Referral Hospital in Uganda between five to ten years reported the prevalence of UTI to be 16.8% and 14.6% respectively. On average at Kam Medical Consult Clinic, patients who turn up in the laboratory are about 20%, and 50% of patients present with recurring UTIs clinically. Therefore, there is a need to establish and investigate the prevalence of bacterial pathogens associated with UTI and multiple pathogens that are not known. Methodology: The cross-sectional study was carried out at Kam medical consult clinic (KMCC) located in Kafeero zone Mulago II Kawempe division. The study population was adults and children presenting with symptoms of urinary tract infection. 120 Midstream urine Samples were collected from patients presenting clinical signs of UTI. The diagnosis was done through macroscopy dry chemistry, microscopy, and culture. Results Among the sampled population, 33% of males had urinary tract infections while 67% of females had urinary tract infections. 88.5% were outpatients while 11.5 % were in-patients The overall prevalence of UTI among patients was 63.3% with children aged (1-10) having a prevalence of 5.8 %. Conclusion and recommendation: E.coli is an etiological agent causing UTIs in male and female patients presenting UTI at Kam Medical Consult Clinic. Other etiological agents included Klebsiella, Coliform, Enterococcus species, staphylococcus aureus, pseudomonas species, and candida species. There is a need to monitor the profile of etiological bacteria of UTI through culture and sensitivity regularly.

Download Full-text

Infeções do Trato Urinário numa Coorte de Transplantados Renais

Acta Médica Portuguesa ◽

10.20344/amp.4959 ◽

2014 ◽

Vol 27 (3) ◽

pp. 364 ◽

Cited By ~ 2

Author(s):

Ana Bispo ◽

Milene Fernandes ◽

Cristina Toscano ◽

Teresa Marques ◽

Domingos Machado ◽

...

Keyword(s):

Risk Factors ◽

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Hospital Admissions ◽

Female Gender ◽

Tract Infections

Introduction: Urinary tract infection is the most common infectious complication following renal transplantation and its frequency is insufficiently studied in Portugal. The aim of this study was to characterize the incidence of urinary tract infections and recurrent urinary tract infections in renal transplant recipients. Material and Methods: This was a retrospective cohort observational study, obtained from clinical files of all patients who received a renal transplant at the Hospital of Santa Cruz, from January 2004 to December 2005, with a mean follow-up period of five years or until date of graft loss, death or loss of follow-up. After a descriptive analysis of the population, we used bivariate tests to identify risk factors for urinary tract infections. Results: A total of 127 patients were included, with a 593 patients.year follow-up. We detected 53 patients (41.7%) presenting with at least one episode of urinary tract infection; 21 patients (16.5%) had recurrent urinary tract infection. Female gender was the only risk factor associated with the occurrence of urinary tract infections (p < 0.001, OR = 7.08, RR = 2.95) and recurrent urinary tract infections (p < 0.001, OR = 4.66, RR = 2.83). Escherichia coli (51.6%), Klebsiella pneumoniae (15.5%) and Enterobacter spp (9.9%) were the most frequently identified pathogens. Patients did not reveal an increased mortality or allograft loss. However, urinary tract infections were the most important cause of hospital admissions. Discussion: Female gender was the only risk factor for urinary tract infections in this population. Escherichia coli was the most frequent agent isolated. Conclusion: Despite preventive measures, urinary tract infections remain an important cause of morbidity and hospital admissions. Keywords: Urinary Tract Infections; Postoperative Complications; Risk Factors; Kidney Transplantation; Portugal.

Download Full-text

Clinical, Epidemiological and Bacteriological Profile of Culture Positive Urinary Tract Infections in Febrile Children – A Cross Sectional Study

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/102 ◽

2021 ◽

Vol 8 (10) ◽

pp. 522-526

Author(s):

Bhavani Shankar Rokkam ◽

Chowdary Babu Menni ◽

Ramu Pedada ◽

Deepak Kumar Alikana

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Urine Culture ◽

Signs And Symptoms ◽

Cross Sectional ◽

Bacteriological Profile ◽

Tract Infections ◽

Culture Positive

BACKGROUND Urinary tract infections (UTI) constitute a common cause of morbidity in infants and children. When associated with abnormalities of urinary tract, they may lead to long-term complications including renal scarring, loss of function and hypertension. Most urinary tract infections remain undiagnosed if investigations are not routinely performed to detect them. Prompt detection and treatment of urinary tract infections and any complicating factors are important. The objective of the study is to know the clinical, epidemiological and bacteriological profile (i.e. clinical signs and symptoms, age, sex, family history, associated urinary tract abnormalities, & causative organisms) of urinary tract infections in febrile children with culture positive urinary tract infection. METHODS This descriptive, cross sectional observational study was conducted at outpatient clinics of our “child health clinics” between May 2016 and April 2017 (one year). All children aged 0 to 12 years with culture positive urinary tract infections were included in this study to evaluate the clinical, epidemiological and bacteriological profile. RESULTS A total of 69 children with culture positive urinary tract infections were included in this study. Out of 69 children included in this study, 36 (52.2 %) were females and 33 (47.8 %) were males. Overall female preponderance was seen and the M: F ratio was 0.9:1. But during first year of life in our study group we had more boys (10, 14.49 %) affected with urinary tract infection than girls. 49.3 % of urinary tract infections in the present study belonged to lower socio-economic status. Most common organism causing urinary tract infection in our group was E. coli (56.5 %). Fever (100 %), anorexia or refusal of feeds (52.2 %), dysuria (46.4 %), vomiting (46.4 %) and abdominal pain (39.1 %) were the predominant clinical manifestations observed in our study. CONCLUSIONS Urinary tract infection is a common medical problem in children and it should be considered as a potential cause of fever in children. As febrile children with urinary tract infection usually present with non-specific signs and symptoms, urine culture should be considered as a part of diagnostic evaluation. KEYWORDS Urinary Tract Infections (UTI), Febrile Children, Bacteriological Profile, Urine Culture

Download Full-text

Association between the frequency of disposable diaper changing and urinary tract infection in children

Paediatrica Indonesiana ◽

10.14238/pi53.2.2013.70-5 ◽

2013 ◽

Vol 53 (2) ◽

pp. 70

Author(s):

Meirina Daulay ◽

Rosmayanti Siregar ◽

Oke Rina Ramayani ◽

Supriatmo Supriatmo ◽

Rafita Ramayati ◽

...

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urine Culture ◽

Bacterial Count ◽

Cross Sectional Study ◽

Cross Sectional ◽

Disposable Diaper ◽

Disposable Diapers ◽

Tract Infections

Background Urinary tract infection (UTI) is the most commoncause of fever in children. Less frequent disposable diaper changingis thought to be a cause ofUTI in children. While wearing a diapei;the perinea! area becomes damp with urine allowing bacteria tomigrate from the anus to the external urethral orifice.Objective To assess for an association between the frequencyof disposable diaper changing and urinary tract infections inchildren.Methods This cross-sectional study was conducted in thechildren's outpatient clinic of Haji Adam Malik Hospital fromApril to June 2010. Urine culture was performed in children withsuspected UTI who wore disposable diapers every day. Subjects'ages ranged from 2 months to 2 years 6 months, with samplesmatched and collected by consecutive sampling. Diagnosis ofUTIwas based on urine cultures with bacterial count 2:: 105/mL. Eightychildren were followed in this study and divided into two groups:positive (n=40) and negative (n=40) urine cultures. Chi squaretest was use d to analyze the association between the frequency ofdaily disposable diapers changing during a one week period andthe urine culture results.Results The frequency of daily disposable diapers changing in80 subjects was as follows: < 4 times (22.5%), 4-5 times (40%),and 2::6 times (37.5%) . The frequency of daily disposable diaperchanging in children with positive urine culture was as fo llows:< 4 times (1 8 out of 40), 4-5 times (22 out of 40), and 2::6 times(O out of 40); (P < 0.0001). The most common bacterial speciesfound in urine cultures was Escherichia coli.Conclusion Lower frequency of daily disposable diaper changingis significantly associated with higher UTI incidence in children.

Download Full-text

Bacterial etiologic agents of urinary tract infection in children in the Islamic Republic of Iran

Eastern Mediterranean Health Journal ◽

10.26719/1997.3.2.290 ◽

1997 ◽

Vol 3 (2) ◽

pp. 290-295

Author(s):

Shahab Modarres ◽

Navideh Nassiri Oskoii

Keyword(s):

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Nalidixic Acid ◽

Urinary Tract Infections ◽

Islamic Republic ◽

Etiologic Agents ◽

Islamic Republic Of Iran ◽

Tract Infections

The bacterial agents of urinary tract infections were studied in 1650 children under 12 years of age between April 1993 and March 1995. It was found that 25.8% [425/1650] of infants and children showed bacteriuria [>10 [5] bacteria per millilitre of urine]. Escherichia coli was responsible for 71.0% of all infections. Infections caused by Proteus spp. were predominantly found in boys. Girls showed a higher prevalence of infection [35.3%] than boys [18.3%], which was statistically highly significant [P < 0.001]. The most commonly isolated bacteria were partially or totally sensitive to the aminoglycosides, chloramphenicol and nalidixic acid

Download Full-text

UJI DIAGNOSTIK UJI DIAGNOSTIK PEMERIKSAAN NITRIT DENGAN KULTUR URIN PADA SUSPEK INFEKSI SALURAN KEMIH

Klinikal Sains : Jurnal Analis Kesehatan ◽

10.36341/klinikal_sains.v9i2.2099 ◽

2021 ◽

Vol 9 (2) ◽

pp. 131-137

Author(s):

Putra Rahmadea Utami

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Urine Culture ◽

Kidney Tissue ◽

High Specificity ◽

Cross Sectional ◽

Negative Results ◽

Tract Infections

Urinary tract infection (UTI) is the second largest infection after respiratory infection and can cause sepsis. Urinary tract infections occur due to the entry of microorganisms in the urinary tract. The urinary tract that is usually infected is the urethra (urethritis), bladder (cystisis), ureter (ureteristis), kidney tissue (pyelonephritis). This study aims to determine the sensitivity and specificity of the diagnostic test of nitrite examination with urine culture in suspected urinary tract infections. The method of this study is a descriptive-analytical study with a cross-sectional retrospective approach, conducted in the STIKes field laboratory with the population studied in this study were all patients diagnosed with urinary tract infection with a sample size of 50 samples. The results of this study showed positive nitrite results as many as 17 people, 34% percentage, and negative nitrite results as many as 33 people with a percentage of 66% and on urine culture examination obtained positive results as many as 17 people with a percentage of 34%, which results in growth of bacterial colonies on cultures> 100,000 CFU / mL and negative results of 33 people with a percentage of 66%. Sensitivity Results 82%, Specificity 90.9%. The conclusion of this study is the value of sensitivity, high specificity so that the nitrite test with urine culture can be applied to help diagnose UTI.

Download Full-text

1700. What Is Specific With Bacterial Escherichia Coli Urinary Tract Infection

Open Forum Infectious Diseases ◽

10.1093/ofid/ofaa439.1878 ◽

2020 ◽

Vol 7 (Supplement_1) ◽

pp. S832-S833

Author(s):

Fatma Hammami ◽

Makram Koubaa ◽

Amal Chakroun ◽

Khaoula Rekik ◽

Fatma Smaoui ◽

...

Keyword(s):

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Resistant Bacteria ◽

Duration Of Treatment ◽

Prostatic Abscess ◽

The Mean ◽

Tract Infections

Abstract Background Bacterial urinary tract infections continue to be a major health problem, responsible for a significant morbidity and mortality. Its prognosis is more severe than non-bacterial forms. The aim of this work was to study the clinical and evolutionary features of bacterial urinary tract infections caused by Escherichia coli (E.coli). Methods We conducted a retrospective study including all patients hospitalized in infectious diseases department for urinary tract infection (UTI) caused by E.coli between 2010 and 2017. Results During the study period, we enrolled 613 cases of UTI caused by E.coli, among whom 75 cases (12.2%) were bacterial. There were 47 females (62.7%). The mean age was 59 ±17 years. Thirty-three patients were aged ≥ 65 years (44%). Diabetes was noted in 38 cases (50.7%) and renal lithiasis in 14 cases (18.7%). A history of UTI was reported in 13 cases (17.3%). The most common clinical presentation was acute pyelonephritis (59 cases; 78.7%) and followed by prostatitis (8 cases; 10.6%). Renal abscess was noted in 5 cases (6.7%) and prostatic abscess in 3 cases (4%). There were 36 cases of multidrug-resistant bacteria (48%). Community-acquired UTI were noted in 70 cases (93.3%). The mean duration of treatment was 18 ± 6 days. Surgery and radiological drainage were indicated in 4 (5.3%) and 2 cases (2.7%), respectively. The outcome was favourable in 58 cases (77.3%). Complications were noted in 10 cases (13.3%) represented mainly by acute renal failure in 4 cases (5.3%). Relapse was noted in 9 cases (12%) and reinfection in 6 cases (8%). Two patients died (2.7%). Conclusion Bacterial urinary tract infections were associated to complications such as renal and prostatic abscess, requiring surgery and long duration of treatment. Disclosures All Authors: No reported disclosures

Download Full-text

Prevalence of microorganisms causing catheter associated urinary tract infections (CAUTI) among catheterised patients admitted in a tertiary care hospital

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20172084 ◽

2017 ◽

Vol 5 (6) ◽

pp. 2367 ◽

Cited By ~ 1

Author(s):

Vinoth M. ◽

Prabagaravarthanan R. ◽

Bhaskar M.

Keyword(s):

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Bacterial Colonization ◽

Tertiary Care ◽

Age Groups ◽

Care Hospital ◽

Cross Sectional ◽

Tract Infections

Background: Catheter-associated urinary tract infection (CAUTI) is an important cause of morbidity and mortality in Indian subjects, affecting all age groups. Bacteriuria orcandiduria is almost inevitable in nearly half of the patients who require an indwelling urinary catheter for more than 5 days. The objective of this study was to find the prevalence of CAUTI infection and to determine their antibiotic profileMethods: The present cross-sectional study included 50 patients admitted to medicine and surgery wards in our hospital. The urine from catheter is collected from each patient and subjected to culture and antibiotic susceptibility testing.Results: The prevalence of catheter associated urinary tract infection in our hospital is about 20% and asymptomatic bacterial colonization is 50% which is nearequal to Danchaivijitr S et al study. The common pathogens found in this study are Escherichia coli (22%), Klebsiella (18%), Enterobacter (8%), Staph. aureus (6%) which include MRSA (4%), Pseudomonas (6%), Enterococcus (4%), Candida sps. (4%) Andproteus (2%).Conclusions: CAUTI has low prevalence 20% and asymptomatic colonisation 50% in our hospital with common pathogen being Escherichia coli. It is one of the important notable pathogen causing nosocomial infection among admitted patients. The patients present mainly as asymptomatic bacterial colonisation and risk of CAUTI increases with longer duration of catheterisation. All patients those who had catheter for more than 6 days, aged 60 and above, should be checked for UTI symptoms. And their urine should be cultured regularly in order to diagnose and prevent CAUTI and its complications which are very dangerous and difficult to treat.

Download Full-text

Frequency of urinary tract infections among pregnant women receiving antenatal care in a tertiary care centre: hospital based cross-sectional study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20205770 ◽

2020 ◽

Vol 10 (1) ◽

pp. 207

Author(s):

Kumari Sadhvi ◽

Varsha Kose

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Antenatal Care ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Culture Sensitivity ◽

Tract Infections ◽

Asymptomatic Women

Background: Urinary tract infections (UTI) are one of the most frequent human bacterial infections, causing substantial morbidity and mortality, with nearly 150 million cases globally per year. The prevalence of UTI (including both asymptomatic bacteriuria and symptomatic infection) in pregnant women in India is reported to range from 3% to 24%. This infection must be adequately diagnosed and efficient treatment must be initiated to prevent maternal and perinatal morbidity.Methods: This was a hospital based cross sectional study. 625 ante natal women recruited during first visit attending antenatal care outpatient department (ANC OPD). We tested their clean catch mid-stream urine sample for routine, microscopic and culture sensitivity test.Results: Out of 625 antenatal women frequency of urinary tract infection was 16.2%. 17% women were symptomatic having one or more symptoms indicative of urinary tract infection and 83% women were asymptomatic. Among symptomatic women, 92.5% women showed culture positivity for one or more bacteria whereas in asymptomatic women, culture was positive in 10.8%. E. coli followed by Klebsiella were the most common isolate identified in both symptomatic and asymptomatic women. On antibiotic sensitivity testing, we found good overall sensitivity of bacteria to commonly used antibiotics such as nitrofurantoin, and norfloxacin but resistant to ampicillin was observed in all women. UTI adversely affects the mother like pyelonephritis, preterm labour and preterm baby and its complications.Conclusions: It is important to identify presence of UTI during pregnancy by doing urine routine and culture sensitivity test in all antenatal women and administration of appropriate antibiotic to affected women so as to reduce the morbidity both in mother and baby.

Download Full-text

The incidence of urinary tract infections in febrile children during a two-year period in Tehran, Iran

Tropical Doctor ◽

10.1258/td.2008.070356 ◽

2008 ◽

Vol 38 (4) ◽

pp. 247-249 ◽

Cited By ~ 4

Author(s):

Yunes Panahi ◽

Fatemeh Beiraghdar ◽

Yashar Moharamzad ◽

Zahra Khalili Matinzadeh ◽

Behzad Einollahi

Keyword(s):

Escherichia Coli ◽

Developing Countries ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Voiding Cystourethrogram ◽

University Hospitals ◽

Urinary Tract Abnormalities ◽

Tract Infections

Of 433 febrile children examined in the paediatric clinics of two university hospitals in Tehran, Iran, 39 (9%) children (27 girls and 12 boys) were diagnosed as having urinary tract infection in which Escherichia coli was the most frequently detected pathogen (84.6%). According to the voiding cystourethrogram, nine (75%) boys and 17 (63%) girls had urinary tract abnormalities. This result is slightly higher than seen in other reports from developing countries.

Download Full-text