scholarly journals The Effect of Air Pollution and Temperature on Pulmonary Function in Healthy People in Xi’an, China

2020 ◽  
Author(s):  
Yang Yao ◽  
Jing Zhou ◽  
Yao Tian ◽  
Xin Diao ◽  
Hui Chen ◽  
...  
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Northwest China ◽  
Potential Interaction ◽  
Healthy People ◽  
Shaanxi Province ◽  
Lag Effects ◽  
Pm 2.5 ◽  
Two Factors ◽  
Acute Adverse Effect

Abstract Background Temperature and air pollution has been reported to be associated with respiratory diseases. However, little is known about these effects on healthy people, and the potential interaction between the two factors is still uncertain. This study aims to estimate the effects of air pollution combined with temperature on lung function in healthy people. Methods The lung function of 132 healthy people was measured in Xi’an, Shaanxi province of Northwest China in summer and winter. Meanwhile, the daily concentrations of air pollution and temperature were obtained from monitoring stations. Statistical analyses were assessed by generalized estimating equations (GEEs). Results Every 10μg/m 3 increase of PM 2.5 concentration, PEF change amount is -0.007L/min (95% CI: -0.013, -0.001 L/min), FEV1 is -0.004 (95% CI: -0.006, -0.001 L/min),FEF25-75% is -0.002(95% CI: -0.003, -0.001 L/min) FEV1/FVC change amount is -0.074 L/min (95% CI: -0.115, -0.033 L/min). Lag effects showed that Lag0 of FEV1, FEV1/FVC and FEF25-75% were more strongly associated with PM2.5. There was no significant interaction between PM 2.5 and temperature. Conclusions Our findings indicate that PM 2.5 has an acute adverse effect on lung function in winter, and the lung function is less affected by temperature change in Xi’an.

scholarly journals The Effect of Air Pollution and Temperature on Pulmonary Function in Healthy People in Xi’an, China

2020 ◽  
Author(s):  
Yang Yao ◽  
Jing Zhou ◽  
Yao Tian ◽  
Hongmei Zhang ◽  
Xin Diao ◽  
...  
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Northwest China ◽  
Potential Interaction ◽  
Healthy People ◽  
Shaanxi Province ◽  
Lag Effects ◽  
Pm 2.5 ◽  
Two Factors ◽  
Background Temperature

Abstract Background: Temperature and air pollution has been reported to be associated with respiratory diseases. However, little is known about these effects on healthy people, and the potential interaction between the two factors is still uncertain. This study aims to estimate the effects of air pollution combined with temperature on lung function in healthy people. Methods: The lung function of 428 healthy people was measured in Xi’an, Shaanxi province of Northwest China in summer and winter. Meanwhile, the daily concentrations of air pollution and temperature were obtained from monitoring stations. Statistical analyses were assessed by generalized estimating equations (GEEs). Results: In winter, Every 10μg/m 3 increase of PM 2.5 concentration, PEF change amount is -0.015L/S(-0.028,-0.002), FEV1 is -0.007 L/S(-0.012,-0.001). The change is -0.022(-0.043,-0.001) and -0.010(-0.011,-0.009) after adjusting for SO 2 . In summer, PEF and FEV1 were were negatively correlated with the concontration of O3. We also found that temperature weaken the adverse effect of PM 2.5 on lung PEF in winter but aggravated effect of O3 on FEV1 in summer. Lag effects showed that Lag0 of FEV1, FEV1/FVC and FEF25-75% were more strongly associated with PM 2.5 . Conclusions: Our findings indicate that Lung function was significantly negative correlated with O3 in summer and PM 2.5 in winter, and a higher temperature has a greater impact on lung function in both summer and winter in Xi’an.

scholarly journals Satellite-Derived PM2.5 Composition and Its Differential Effect on Children’s Lung Function

2020 ◽  
Vol 12 (6) ◽  
pp. 1028 ◽  
Author(s):  
Khang Chau ◽  
Meredith Franklin ◽  
W. James Gauderman
Keyword(s):  
Air Pollution ◽  
Lung Function ◽  
Satellite Observations ◽  
Children's Health ◽  
Children’S Health ◽  
Health Study ◽  
Gradient Boosting ◽  
Chemical Components ◽  
Support Vector ◽  
Pm 2.5

Studies of the association between air pollution and children’s health typically rely on fixed-site monitors to determine exposures, which have spatial and temporal limitations. Satellite observations of aerosols provide the coverage that fixed-site monitors lack, enabling more refined exposure assessments. Using aerosol optical depth (AOD) data from the Multiangle Imaging SpectroRadiometer (MISR) instrument, we predicted fine particulate matter, PM 2.5 , and PM 2.5 speciation concentrations and linked them to the residential locations of 1206 children enrolled in the Southern California Children’s Health Study. We fitted mixed-effects models to examine the relationship between the MISR-derived exposure estimates and lung function, measured as forced expiratory volume in 1 second (FEV 1 ) and forced vital capacity (FVC), adjusting for study community and biological factors. Gradient Boosting and Support Vector Machines showed excellent predictive performance for PM 2.5 (test R 2 = 0.68 ) and its chemical components (test R 2 = –0.71). In single-pollutant models, FEV 1 decreased by 131 mL (95% CI: − 232 , − 35 ) per 10.7-µg/m 3 increase in PM 2.5 , by 158 mL (95% CI: − 273 , − 43 ) per 1.2-µg/m 3 in sulfates (SO 4 2 − ), and by 177 mL (95% CI: − 306 , − 56 ) per 1.6-µg/m 3 increase in dust; FVC decreased by 175 mL (95% CI: − 310 , − 29 ) per 1.2-µg/m 3 increase in SO 4 2 − and by 212 mL (95% CI: − 391 , − 28 ) per 2.5-µg/m 3 increase in nitrates (NO 3 − ). These results demonstrate that satellite observations can strengthen epidemiological studies investigating air pollution health effects by providing spatially and temporally resolved exposure estimates.

scholarly journals Association of Calcium Supplementation During Pregnancy with the Birth Weight of Single-Born Neonates in Rural Northwest China

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1106-1106
Author(s):  
Gao Xiangyu ◽  
Mi Baibing ◽  
Dang Shaonong ◽  
Yan Hong
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Regression Models ◽  
Calcium Supplementation ◽  
Northwest China ◽  
Incidence Rates ◽  
Shaanxi Province ◽  
Significant Difference ◽  
Birth Weight Percentile ◽  
Weight Percentile

Abstract Objectives To investigate the association of calcium supplementation during the pregnancy with the birth weight of single-born neonates. Methods The survey employed a multistage, stratified and random sampling to investigate 15–49 aged pregnant women in 2010 to 2013 in Shaanxi province. A self - designed questionnaire was utilized. Birth weight between the 10(th) and 90(th) percentile was classified as appropriate for gestational age(AGA) infants. Chi-square test and logistic regression models were conducted to evaluate the association of calcium supplementation with single-born neonatal birth weight. Results A total of 28,490 women was enrolled in this study, 17 349 (60.9%) of participants had calcium supplementation during pregnancy. The incidence rates of small and large gestational age infants were 13.5% and 8.3%, respectively. The study conducted that calcium supplementation had a statistically significant difference in SGA (birth weight percentile <10) (P < 0.01). After adjusting the regression models by confounding factors, we found that calcium supplementation was still protective towards SGA birth, the difference was statistically significant (OR = 0.89, 95% CI: 0.82–0.96, P < 0.05), but there was no significant difference in the birth to LGA (birth weight percentile <10). Conclusions Calcium supplementation during pregnancy reduced the risk of SGA, but was not associated with the birth of LGA. Funding Sources

scholarly journals Quantifying Air Pollutant Variations during COVID-19 Lockdown in a Capital City in Northwest China

Atmosphere ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 788
Author(s):  
Rong Feng ◽  
Hongmei Xu ◽  
Zexuan Wang ◽  
Yunxuan Gu ◽  
Zhe Liu ◽  
...  
Keyword(s):  
Air Pollution ◽  
Air Quality ◽  
Rural Areas ◽  
Vehicle Emissions ◽  
Motor Vehicle ◽  
Northwest China ◽  
Air Pollutant ◽  
Capital City ◽  
Air Pollution Control ◽  
Motor Vehicle Emissions

In the context of the outbreak of coronavirus disease 2019 (COVID-19), strict lockdown policies were implemented to control nonessential human activities in Xi’an, northwest China, which greatly limited the spread of the pandemic and affected air quality. Compared with pre-lockdown, the air quality index and concentrations of PM2.5, PM10, SO2, and CO during the lockdown reduced, but the reductions were not very significant. NO2 levels exhibited the largest decrease (52%) during lockdown, owing to the remarkable decreased motor vehicle emissions. The highest K+ and lowest Ca2+ concentrations in PM2.5 samples could be attributed to the increase in household biomass fuel consumption in suburbs and rural areas around Xi’an and the decrease in human physical activities in Xi’an (e.g., human travel, vehicle emissions, construction activities), respectively, during the lockdown period. Secondary chemical reactions in the atmosphere increased in the lockdown period, as evidenced by the increased O3 level (increased by 160%) and OC/EC ratios in PM2.5 (increased by 26%), compared with pre-lockdown levels. The results, based on a natural experiment in this study, can be used as a reference for studying the formation and source of air pollution in Xi’an and provide evidence for establishing future long-term air pollution control policies.

scholarly journals Arbuscular mycorrhizal symbiosis facilitates apricot seedling (Prunus sibirica L.) growth and photosynthesis in northwest China

2021 ◽  
Author(s):  
Yinli Bi ◽  
Linlin Xie ◽  
Zhigang Wang ◽  
Kun Wang ◽  
Wenwen Liu ◽  
...  
Keyword(s):  
Arbuscular Mycorrhizal ◽  
Am Fungi ◽  
Northwest China ◽  
Shaanxi Province ◽  
Mycorrhizal Symbiosis ◽  
Seedling Physiology ◽  
Grassland Ecosystems ◽  
Time Period ◽  
Seedling Biomass ◽  
Experimental Treatments

AbstractArbuscular mycorrhizal (AM) fungi can successfully enhance photosynthesis (Pn) and plants growth in agricultural or grassland ecosystems. However, how the symbionts affect species restoration in sunlight-intensive areas remains largely unexplored. Therefore, this study’s objective was to assess the effect of AM fungi on apricot seedling physiology, within a specific time period, in northwest China. In 2010, an experimental field was established in Shaanxi Province, northwest China. The experimental treatments included two AM fungi inoculation levels (0 or 100 g of AM fungal inoculum per seedling), three shade levels (1900, 1100, and 550 µmol m−2 s−1), and three ages (1, 3, and 5 years) of transplantation. We examined growth, Pn, and morphological indicators of apricot (Prunus sibirica L.) seedling performances in 2011, 2013, and 2015. The colonization rate in mycorrhizal seedlings with similar amounts of shade is higher than the corresponding controls. The mycorrhizal seedling biomass is significantly higher than the corresponding non-mycorrhizal seedling biomass. Generally, Pn, stomatal conductance (Gs), transpiration rate (Tr), and water use efficiency are also significantly higher in the mycorrhizal seedlings. Moreover, mycorrhizal seedlings with light shade (LS) have the highest Pn. WUE is increased in non-mycorrhizal seedlings because of the reduction in Tr, while Tr is increased in mycorrhizal seedlings with shade. There is a significant increase in the N, P, and K fractions detected in roots compared with shoots. This means that LS had apparent benefits for mycorrhizal seedlings. Our results also indicate that AM fungi, combined with LS, exert a positive effect on apricot behavior.

scholarly journals Spectrum analysis of inborn errors of metabolism for expanded newborn screening in a northwestern Chinese population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ruixue Zhang ◽  
Rong Qiang ◽  
Chengrong Song ◽  
Xiaoping Ma ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Newborn Screening ◽  
Inborn Errors Of Metabolism ◽  
Northwest China ◽  
Methylmalonic Acidemia ◽  
Shaanxi Province ◽  
Inborn Errors ◽  
Organic Acidurias ◽  
Genetic Characteristics ◽  
Disease Spectrum ◽  
Expanded Newborn Screening

AbstractExpanded newborn screening facilitates early identification and intervention of patients with inborn errors of metabolism (IEMs), There is a lack of disease spectrum data for many areas in China. To determine the disease spectrum and genetic characteristics of IEMs in Xi'an city of Shaanxi province in northwest China, 146152 newborns were screening by MSMS from January 2014 to December 2019 and 61 patients were referred to genetic analysis by next generation sequencing (NGS) and validated by Sanger sequencing. Seventy-five newborns and two mothers were diagnosed with IEMs, with an overall incidence of 1:1898 (1:1949 without mothers). There were 35 newborns with amino acidemias (45.45%, 1:4176), 28 newborns with organic acidurias (36.36%, 1:5220), and 12 newborns and two mothers with FAO disorders (18.18%; 1:10439 or 1:12179 without mothers). Phenylketonuria and methylmalonic acidemia were the two most common disorders, accounting for 65.33% (49/75) of all confirmed newborn. Some hotspot mutations were observed for several IEMs, including PAH gene c.728G>A for phenylketonuria; MMACHC gene c.609G>A and c.567dupT, MMUT gene c.323G>A for methylmalonic acidemia and SLC25A13 gene c.852_855del for citrin deficiency. Our study provides effective clinical guidance for the popularization and application of expanded newborn screening, genetic screening, and genetic counseling of IEMs in this region.

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