scholarly journals Chronic cough in postmenopausal women and its associations to climacteric symptoms

Author(s):  
Volker Ziller ◽  
Thea Sophie Oppermann ◽  
Werner Cassel ◽  
Olaf Hildebrandt ◽  
Rolf Kroidl ◽  
...  

Abstract BackgroundPostmenopausal women often have chronic cough, which is likely caused by hormonal changes affecting lung function and the mucous membrane of the airways, causing hypersensitivity of the cough reflex. Therefore, postmenopausal hormonal changes could play a key role in the association between increased cough and menopause. The aim of this study is to evaluate the relation of chronic cough and postmenopausal symptoms.MethodsWe performed a questionnaire-based cohort study in generally healthy postmenopausal women (age 45–65 years). Women with cough of known origin were excluded. Comorbidities, medication and baseline data were collected. The Menopause Rating Scale II (MRS II) was combined with the Leicester Cough Questionnaire (LCQ). Groups were divided in chronic cough versus non-coughing participants, chronic cough was defined as symptoms over 8 weeks. We performed correlations and logistic regression for predicting cough based on postmenopausal symptoms.ResultsSixty-six of 200 women (33%) reported mild to heavier symptoms of chronic cough over 8 weeks. No significant differences in baseline data (age, BMI, onset of menopause, years since menopause, concomitant diseases, and medication) were found between coughing and non-coughing women. The MRS II showed higher menopausal symptoms in patients with cough, with significant differences in 2 of the 3 MRS-domains (urogenital (p < 0.001) and somato-vegetative (p < 0.001)). Climacteric symptoms correlated strongly with parameters of cough (p<0.001). On the basis of the MRS total score (p<0.001) and the somato-vegetative and urogenital domains (p<0,05), the prediction for respiratory complaints could be shown.DiscussionChronic cough was significantly associated with menopausal symptoms. Therefore chronic cough as a possible climacteric symptom and its underlying mechanisms should be further explored.

2020 ◽  
Author(s):  
Neda Mohamadzade ◽  
Shahideh Jahanian Sadatmahalleh ◽  
Saeideh Ziaei ◽  
Narges Zaeemzadeh ◽  
Anoshirvan Kazemnejad

Abstract Background: Due to the decrease of estrogen levels in postmenopausal females, menopause can be associated with musculoskeletal pains. This study was designed to assess the possible association between musculoskeletal pains, serum estradiol level, and climacteric symptoms in postmenopausal women.Methods: This cross-sectional study was conducted on 307 postmenopausal females selected by convenience sampling method. Data collection procedure lasted from October 2016 to September 2018. The required data were collected using the Menopause Rating Scale (MRS), Örebro Musculoskeletal Pain Questionnaire (ÖMPQ), and a questionnaire containing personal data. The blood sample was taken to measure the estradiol level. Results: There was a direct relationship between musculoskeletal pains and menopause symptoms (p<0.001), age (p=0.03), parity (p=0.01), and BMI (p=0.03) and an indirect association between musculoskeletal pain and marriage age (p=0.009), age of first pregnancy (0.017), estradiol level (p<0.001) and education level (p=0.002). The regression analysis results showed that menopause symptoms were the strongest predictor of musculoskeletal pains among all the variables.Conclusions: The findings of the present study showed that although various parameters are associated with musculoskeletal pains, climacteric symptoms are the most important predictive parameters of musculoskeletal pains.


2019 ◽  
Vol 4 (2) ◽  

Background: Reports of prevalence rates of depression in postmenopause show inconsistent results, with some studies demonstrating an increase in depressive symptoms whereas others show a decrease or no difference. Objectives: To estimate the prevalence and define some risk factors of depression in postmenopausal women aged 45-65 years in primary health care settings in Riyadh, Saudi Arabia. Subjects and Methods: This cross-sectional study was conducted throughout the period June-August, 2018 at King Abdul Aziz Medical City-National Guard (KAMC-NG) in Riyadh, Saudi Arabia, in three large primary care centers. It included a sample of postmenopausal women who completed at least 12 months of amenorrhea and aged between 45 and 65 years. The Arabic version of PHQ-9 was utilized to detect depression and Menopausal rating scale (MRS) was used to assess the severity of menopausal symptoms. Results: The study included 300 women. The prevalence of major depressive symptoms among them was 29%. More than half (60.7%) of the respondents had moderate social support, three quarters (75%) scored mild to severe symptoms on the menopausal rating scale while 25% were asymptomatic.Women who were: unmarried (84.2%), housewives (79.2%), illiterate (83.2%), menopaused since≥10 years (87.5%), having more than five children (81.4%), underwent oophorectomy (100%), with poor social support (93.9%) and never exercised (82.4%) were more likely to report mild to severe symptoms. Also, significantly higher percentages of participants who have hypertension (81.9%), diabetes (82.1%), Dyslipedemia (88.1%) and hypothyroidism (81.4 %) experienced mild to severe menopausal symptoms, p<0.05. The degree of severity on the PHQ has strong significant (P<0.001) correlation with marital status, employment status, educational level and income. Conclusion: Depression is a relatively common disorder among postmenopausal women in Riyadh. Some sociodemographic indicators were identified. Care should be paid to this important group and further larger studies are recommended.


2021 ◽  
Vol 12 (1) ◽  
pp. 136-140
Author(s):  
Aariya Srinivasan ◽  
Archana kumari

Menopausal symptoms can often be distressing and affect the normal activities of women in their middle age. This can significantly reduce their quality of life. This study was done to assess the prevalence of vasomotor menopausal symptoms using a modified menopause rating scale (MRS) in Peri and postmenopausal women. A cross-sectional observational study was done on 100 middle-aged women (40-65 yrs) during the period January-June 2020 using the modified menopause rating scale (MRS). The mean age of the respondents in the study was 52.71 yrs. The mean age at menopause is 56 yrs. The commonly found symptoms were joint and muscular discomfort (80%), physical and mental exhaustion (65%) and sleeping problems (50%) appears to be the most commonly experienced symptoms by these women. The other symptoms are hot flushes and night sweats (46%), irritability (40%), dryness of vagina (38%), anxiety (36%), depressive mood (34%), sexual problems(30%), heart discomfort (16%) bladder problems (14%). This study showed that the typical vasomotor symptoms of menopause like sweating and hot flushes were comparatively lower than that of somatic symptoms like joint and muscular discomfort, mental and physical exhaustion in general. At the same time, postmenopausal women experienced more of urogenital symptoms, while Peri and premenopausal women experienced somatic and psychological symptoms.


Author(s):  
Socorro Rejany Sales Silva Trento ◽  
Alberto Madeiro ◽  
Andréa Cronemberger Rufino

Abstract Objective To assess the sexual function and associated factors in postmenopausal women. Methods This a descriptive, cross-sectional study with 380 women aged 40 to 65 years, users of public health services in 2019. Questionnaires were applied on demographic characteristics, on climacteric symptoms (menopause rating scale) and on sexual function (sexual quotient, female version). Bivariate and multiple analyses by logistic regression were performed, with adjusted odds ratios (ORad) and 95% confidence intervals (95%CIs). Results More than half (243/64%) of the participating women were at risk of sexual dysfunction, with lower scores in the domains of sexual desire and interest, comfort, orgasm, and satisfaction. Women with a partner (ORad 2.07; 95%CI 1.03–4.17) and those who reported sleep problems (ORad 2.72; 95%CI 1.77–4.19), depressed mood (ORad 2.03; 95%CI 1.32–3.10), sexual complaints (ORad 8.16; 95%CI 5.06–13.15), and vaginal dryness (ORad 3.44; 95%CI 2.22–5.32) showed greater chance of sexual dysfunction. Conclusion There was a high prevalence of sexual dysfunction, with the influence of conjugality and climacteric symptoms on sexual function.


Author(s):  
Fereshteh Dadfar ◽  
Kourosh Bamdad

Background: The menopausal symptoms are the most common problems in postmenopausal women. Due to the side effects of hormone replacement therapy, the use of medicinal herbs has increased for the treatment of menopausal symptoms. Objective: The aim of this study was to evaluate the effect of Saliva officinal is on the decreasing of the severity of the menopausal symptoms in postmenopausal women. Materials and Methods: The study was performed on 30 postmenopausal women aged 46–58 yr referred to the healthcare center of Darab who experienced various degrees of postmenopausal symptoms. The severity of menopausal symptoms is recorded by a Menopause Rating Scale. Participants received a 100 mg capsule of sage extract daily for 4 wk. The severity of postmenopausal symptoms was compared before and after four weeks of the consumption of sage extract. Results: The results showed the severity of hot flashes, night sweats, panic, fatigue, and concentration had significant differences before and after the consumption of sage extract. Conclusion: It was concluded that Saliva officinal is were effective to change the severity of some of the menopausal symptoms in postmenopausal women.


2016 ◽  
Vol 8 (10) ◽  
pp. 34 ◽  
Author(s):  
Mahin Nazari ◽  
Samaneh Farmani ◽  
Mohammad Hosein Kaveh ◽  
Haleh Ghaem

<p><strong>Introduction: </strong>Health and lifestyle of women are of great importance in some periods of life, such as menopause. Since postmenopausal women are considered as a vulnerable group of the society, finding a strategy to improve their health seems necessary.</p><p><strong>Methods:</strong> This experimental study with pretest-posttest design was carried out on 200 postmenopausal women between 45 and 60 years old in Ramjerd, Marvdasht, Iran, in 2014. The women who met the inclusion criteria of the study were selected by simple random sampling. The data were collected using demographic information questionnaire, Menopause Rating Scale (MRS), and Walker’s Health Promoting Lifestyle Profile (HPLP<strong>II</strong>). The data were entered into the SPSS statistical software (version 19) and were analyzed using descriptive statistics, paired t-test, independent t-test, and chi-square test. P-values less than 0.05 were considered as statistically significant.</p><p><strong>Results:</strong> The results of paired t-test showed a significant difference in the mean scores of health promoting lifestyle and MRS in the experimental group (P&lt;.05), but not in the control group (P&gt;.05).</p><p><strong>Conclusion:</strong> Lifestyle education was effective in health promoting behaviors and menopausal symptoms. After the educational intervention, health promoting behaviors increased and menopausal symptoms decreased in the postmenopausal women. Therefore, educational interventions based on health promoting lifestyles can be used as an appropriate strategy to reduce postmenopausal women’s menopausal symptoms and improve their health.<strong></strong></p>


2019 ◽  
Vol 28 (1) ◽  
pp. 40-6
Author(s):  
Andon Hestiantoro ◽  
Shanty Olivia Jasirwan ◽  
Martina Wiwie ◽  
Amalia Shadrina ◽  
Nurhadi Ibrahim ◽  
...  

BACKGROUND Women in menopause experience dramatic alterations in gonadal hormone concentrations, including diminished estradiol levels. It has been hypothesized that these hormonal changes may be responsible for the occurrences of menopausal symptoms, such as hot flushes, sleep disruption, night sweats, and irritability, as well as mild cognitive impairment (MCI) in postmenopausal women. Therefore, this study was aimed to determine if there is any association between hormonal changes and menopausal symptoms, including MCI in postmenopausal women.METHODS A total of 245 postmenopausal women were recruited for this cross-sectional study and classified into 2 groups; MCI and non-MCI groups. Diagnosis of MCI was made using the modified Petersen criteria. Variables such as subjects’ age, duration of menopause, menopausal symptoms, anthropometric status, hormone levels, and cognitive status were assessed and statistically analyzed.RESULTS Of the 245 subjects enrolled in this study, 53.9% had MCI. Multivariate analysis found that sleep disruption and estradiol levels were independent risk factors of MCI in postmenopausal women. No significant correlation was found between menopausal symptoms and estradiol concentration.CONCLUSIONS Low estradiol levels were associated with higher risks of experiencing menopausal symptoms and MCI. Sleep disruption and estradiol levels were the most influential factors in the development of MCI in postmenopausal women.


2020 ◽  
Vol 6 (2) ◽  
pp. 57-62
Author(s):  
Juminten Saimin ◽  
Steven Ridwan ◽  
Mono Valentino Yohanis ◽  
Lianawati Lianawati ◽  
Arimaswati Arimaswati ◽  
...  

Background: Menopausal symptoms are common problem in menopausal women. The severity of menopausal symptoms is influenced by the interaction of biological, genetic and nutritional factors.Objective: This study aimed to determine correlation between menopausal symptoms and fish consumption of postmenopausal women in the coastal areas.Method: This was a cross-sectional study conducted on 234 postmenopausal women in the coastal areas of Southeast Sulawesi. Severity of menopausal symptoms was assessed using Menopause Rating Scale (MRS). Quantity of fish consumption was calculated using 24-hour recall questionnaires. Frequency of fish consumption was evaluated using Food Frequency Questionnaires (FFQ). Data analysis used Chi-square test with a significance value of p=0.05.Results: The majority of fish consumption was sufficient in quantity (81.6%) and frequency (95.3%). Menopausal symptoms are found to be very mild (14.1%), mild (36.3%), moderate (38.5%), and severe (11.1%). There was a correlation between menopausal symptoms and the quantity of fish consumption (p=0.000), and between menopausal symptoms and the frequency of fish consumption (p=0.000).  Conclusion: There was a correlation between menopausal symptoms and fish consumption of postmenopausal women, both in the quantity and frequency. Therefore, increasing the quantity and frequency of fish consumption will reduce the severity of menopausal symptoms.


Author(s):  
Vangara Sushmitha ◽  
Nishita Shettian

Background: Menopause is defined as complete cessation of menses for a period of twelve months or more as a result of complete loss of ovarian follicular activity. Issues related to menopausal symptoms are complicated in terms of experience, severity, and dynamics of the symptoms. Various studies had showed that these symptoms vary among individuals depending on the menopausal stage, ethnicity, geographic location, and other factors menopause rating scale is an effective tool to assess the severity of these symptoms. The aims and objectives of this study were to assess the commonly reported menopausal symptoms among the women of Dakshina Kannada district using a modified menopause rating scale.Methods: This study was conducted in A.J Institute of Medical Sciences and Research Centre from January 2019. A total of 360 postmenopausal women were interviewed using predesigned questionnaire. Menopausal symptoms were assessed using modified menopause rating scale.Results: Majority of women attained menopause at the age of 51-55 years and the calculated mean age was 51.33+3.36. 85% were symptomatic with at least one symptom. The most common symptom reported was joint and muscular discomfort (80%), psychological symptoms like depressive mood (68%), vasomotor symptoms (60%), sleep disorders (50%) urogenital problem (30%). The menopausal symptoms were more prevalent in women of lower socioeconomic status and the ones who were illiterate and this difference was significant.Conclusions: There is an increasing need for establishment of specific health intervention for postmenopausal women by specialty clinics as the burden of menopausal symptoms is high in the Indian women due to lack of awareness, socio cultural and economic factors, and inaccessibility of health services, which may negatively affect the attitude of women towards menopause.


2017 ◽  
Vol 23 (4) ◽  
pp. 271-279 ◽  
Author(s):  
Juliene G Costa ◽  
Jéssica S Giolo ◽  
Igor M Mariano ◽  
Jaqueline P Batista ◽  
Ana Luiza A Ribeiro ◽  
...  

Background: Exercise and supplementation with isoflavones are therapies used to prevent and treat climacteric symptoms. Aim: To verify the effects of 10 weeks of combined aerobic and resistance training and isoflavone supplementation on climacteric symptoms in postmenopausal women. Methods: A randomised, double-blind, controlled clinical trial was performed. A total of 32 postmenopausal women, aged 54.4 ± 5.4 years, with a body mass index of 26.6 ± 3.0 kg/m2 and 5.6 ± 4.6 years after menopause, were randomly assigned to groups: placebo and exercise (PLA + EXE, n = 15) or 100 mg of isoflavone and exercise (ISO + EXE, n = 17). At the beginning and after 10 weeks of aerobic + resistance (20 min each, moderate intensity) training, climacteric symptoms were evaluated using the Blatt–Kupperman Menopausal Index, Cervantes Scale and Menopause Rating Scale. ANCOVA was used for analysis between groups and at different times, with the covariate adjusted by the pre-value. The level of significance considered was p < 0.05. Results: A reduction in climacteric symptoms was observed in both groups, without differences between the interventions. The reductions were 45% and 50% for the Blatt–Kupperman Menopausal Index, 41% and 52% for the MRS and 39% and 39% for the Cervantes Scale in the ISO + EXE and PLA + EXE groups, respectively. In the descriptive analysis of the Blatt–Kupperman Menopausal Index values, there was an increase in the absence of symptoms from 48−77% in the ISO + EXE group and 24−58% in the PLA + EXE group. Conclusions: A period of 10 weeks of combined training was effective in improving climacteric symptoms in post-menopausal women. However, isoflavone supplementation did not promote additional effects in improving symptoms.


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