Serum Uric Acid and Calcium Levels as Predictors of Hematoma Volume in Emergency Patients Experiencing Spontaneous Intracerebral Hemorrhage
Abstract Objective: To investigate the relationship between serum uric acid and calcium levels and hematoma volume in emergency patients who experienced spontaneous intracerebral hemorrhage (SICH).Methods: Data from 105 patients who experienced SICH and 92 with non-intracerebral hemorrhage (control group) were retrospectively analyzed. Data collected included clinical characteristics, and serum biochemical and blood coagulation indices. Hematoma volume was calculated using computed tomography (CT) imaging data.Results: Individuals who experienced SICH exhibited higher serum uric acid levels and longer activated partial thromboplastin and thrombin times compared to those with non-intracerebral hemorrhage (all P < 0.05). In contrast, serum calcium levels in patients with SICH were lower than those of the control group (P < 0.05). Hypocalcemic patients exhibited a greater median baseline hematoma volume than normocalcemic patients. Conclusion: High serum uric acid and low calcium levels may be predictors of larger hematoma volumes among individuals who experience SICH.