scholarly journals Exploring Related Factors of Chronic Obstructive Pulmonary Disease Based on Elastic Net and Bayesian Network

Author(s):  
Dichen Quan ◽  
Jiahui Ren ◽  
Hao Ren ◽  
Liqin Linghu ◽  
Xuchun Wang ◽  
...  

Abstract Objective This study aimed to construct Bayesian networks to analyze the network relationship between COPD and its related factors, and to explore the influencing intensity on COPD through network reasoning. Method Firstly Elastic Net and MMHC hybrid algorithm were adopted to screen the variables of the data of COPD in Shanxi Province from 2014 to 2015 and construct Bayesian networks respectively, and the parameters were estimated by maximum likelihood estimation. Results After feature selection by Elastic Net, 10 variables closely related to COPD finally entered the model. The COPD Bayesian networks constructed by MMHC algorithm showed that smoking status, household air pollution, family history, cough, air hunger or dyspnea were directly related to COPD, in which smoking status, household air pollution and family history were the parent nodes of COPD, and cough, air hunger or dyspnea represented the child nodes of COPD. In other words, smoking status, household air pollution, family history were related to the occurrence of COPD, and COPD would affect cough, air hunger or dyspnea. Gender was indirectly linked to COPD through smoking status. Conclusion Using Elastic Net to knock out some weakly-associated influencing factors of COPD in the variable screening stage, Bayesian networks could reveal the complex network relationship between COPD and its relevant factors well, making it more convenient to carry out targeted prevention and control of COPD. As such, Bayesian networks enjoyed a good prospect of application in analyzing disease-related factors.

2022 ◽  
Author(s):  
Dichen Quan ◽  
Jiahui Ren ◽  
Hao Ren ◽  
Liqin Linghu ◽  
Xuchun Wang ◽  
...  

Abstract This study aimed to construct Bayesian networks(BNs) to analyze the network relationship between those influencing factors and COPD, and to explore their intensity of effect on COPD through network reasoning. Elastic Net and Max-Min Hill-Climbing(MMHC) hybrid algorithm were adopted to screen the variables on the monitoring data of COPD among residents in Shanxi Province, China from 2014 to 2015, and construct BNs respectively. After variables selection by Elastic Net, 10 variables closely related to COPD were selected finally. The BNs constructed by MMHC showed that smoking status, household air pollution, family history, cough, air hunger or dyspnea were directly related to COPD, and Gender was indirectly linked to COPD through smoking status. Moreover, smoking status, household air pollution and family history were the parent nodes of COPD, and cough, air hunger or dyspnea represented the child nodes of COPD. In other words, smoking status, household air pollution and family history were related to the occurrence of COPD, and COPD would make patients’ cough, air hunger or dyspnea worse. Generally speaking, BNs could reveal the complex network relationship between COPD and its relevant factors well, making it more convenient to carry out targeted prevention and control of COPD.


2011 ◽  
Vol 81 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Rahime Bedir Findik ◽  
Nurcihan Karakurt Hascelik ◽  
Kadir Okhan Akin ◽  
Ayse Nurcan Unluer ◽  
Jale Karakaya

Background: Striae gravidarum, a clinical condition commonly seen in pregnant women, produces serious cosmetic problems and may lead to psychological problems. Aim: The present study investigated whether there was any relation between the presence of striae in primigravid pregnant women and blood vitamin C levels, and factors thought to contribute to the formation of striae such as family history, weight gained during pregnancy, smoking status, abdominal and thigh circumference, and age. Methods: Overall, 69 primigravid women attending routine antenatal follow-up and, using prophylactic iron and vitamin preparations, underwent investigation. All were pregnant 36 or more weeks. Scoring was based on striae examination and whether striae were present. The relation between the presence of striae, vitamin C blood levels, and other factors was investigated. Results and Conclusions: Multiple logistic regression analysis showed a significant relation between the presence of striae and blood vitamin C levels (p = 0.046) and between the presence of striae and family history (p = 0.023). No significant relation was found between the presence of striae and age, weight gained during pregnancy, abdominal and thigh circumference, or smoking status. It was concluded that further, more comprehensive studies on the issue are required.


2021 ◽  
Author(s):  
Esong Miranda Baame ◽  
André Pascal Goura ◽  
Bertrand Hugo Ngahane Mbatchou ◽  
Berenice Walage ◽  
Herman Styve Yomi Simo ◽  
...  

Abstract Background: Household air pollution (HAP) is a recognised risk factor for many diseases, including respiratory diseases, cardiovascular/circulatory disorders, adverse pregnancy outcomes and cataracts. Population exposure to biomass fuels, including wood, varies among countries and from one fuel source to the other. This study aimed to investigate the different sources of HAP in peri-urban and rural communities in Cameroon. Methods: A cross-sectional survey was conducted in a representative sample of households from the Dschang Health District (DHD) region. This included 848 homes in which a range of fuels for cooking including biomass (firewood, charcoal, sawdust), kerosene and liquefied petroleum gas (LPG) were used both indoors and outdoors. Results: Of the study households, 651 (77%) reported exclusive use of firewood and 141 (17%) reported using more than one source of fuel. Exclusive use of firewood was greater in rural communities (94%) than in peri-urban communities (38%). In peri-urban communites, use of multiple fuels including LPG, wood, sawdust and kerosene, was more common (44.75%). A total of 25.03% of households in both peri-urban and rural communities reported using bottled gas (or liquified petroleum gas (LPG) for cooking. Motivations for choice of fuel included, price, availability (easy access), rapidity, tradition or culture related factorsConclusion: Wood is the main cooking fuel in both peri-urban and rural communities in the Dschang Health District. Work to help households (especially those who are resource poor) to adopt LPG equipment for cooking, and use in a more exclusive way is required.


Atmosphere ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 422
Author(s):  
H. Dean Hosgood ◽  
Madelyn Klugman ◽  
Keitaro Matsuo ◽  
Alexandra J. White ◽  
Atsuko Sadakane ◽  
...  

Household air pollution (HAP) is of public health concern, with ~3 billion people worldwide (including >15 million in the US) exposed. HAP from coal use is a human lung carcinogen, yet the epidemiological evidence on carcinogenicity of HAP from biomass use, primarily wood, is not conclusive. To robustly assess biomass’s carcinogenic potential, prospective studies of individuals experiencing a variety of HAP exposures are needed. We have built a global consortium of 13 prospective cohorts (HAPCO: Household Air Pollution Consortium) that have site- and disease-specific mortality and solid fuel use data, for a combined sample size of 587,257 participants and 57,483 deaths. HAPCO provides a novel opportunity to assess the association of HAP with lung cancer death while controlling for important confounders such as tobacco and outdoor air pollution exposures. HAPCO is also uniquely positioned to determine the risks associated with cancers other than lung as well as nonmalignant respiratory and cardiometabolic outcomes, for which prospective epidemiologic research is limited. HAPCO will facilitate research to address public health concerns associated with HAP-attributed exposures by enabling investigators to evaluate sex-specific and smoking status-specific effects under various exposure scenarios.


2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Jinhua Pan ◽  
Zeping Ren ◽  
Wenhan Li ◽  
Zhen Wei ◽  
Huaxiang Rao ◽  
...  

2020 ◽  
Author(s):  
Esong Miranda Baame ◽  
André Pascal Goura ◽  
Bertrand Hugo Ngahane Mbatchou ◽  
Berenice Walage ◽  
Herman Styve Yomi Simo ◽  
...  

Abstract Background: Household air pollution (HAP) is a recognised risk factor for many diseases, including respiratory diseases, cardiovascular/circulatory disorders, adverse pregnancy outcomes and cataracts. Population exposure to biomass fuels, including wood, varies among countries and from one fuel source to the other. This study aimed to investigate the different sources of HAP in peri-urban and rural communities in Cameroon. Methods: A cross-sectional survey was conducted in a representative sample of households from the Dschang Health District (DHD) region. This included 848 homes in which a range of fuels for cooking including biomass (firewood, charcoal, sawdust), kerosene and liquefied petroleum gas (LPG) were used both indoors and outdoors. Results: Of the study households, 651 (77%) reported exclusive use of firewood and 141 (17%) reported using more than one source of fuel. Exclusive use of firewood was greater in rural communities (94%) than in peri-urban communities (38%). In peri-urban communites, use of multiple fuels including LPG, wood, sawdust and kerosene, was more common (44.75%). A total of 25.03% of households in both peri-urban and rural communities reported using bottled gas (or liquified petroleum gas (LPG) for cooking. Motivations for choice of fuel included, price, availability (easy access), rapidity, tradition or culture related factorsConclusion: Wood is the main cooking fuel in both peri-urban and rural communities in the Dschang Health District. Work to help households (especially those who are resource poor) to adopt LPG equipment for cooking, and use in a more exclusive way is required.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fithria Fithria ◽  
Muhammad Adlim ◽  
Syarifah Rauzatul Jannah ◽  
Teuku Tahlil

Abstract Background The prevalence of smoking among adolescents is high in Indonesia. Therefore, this qualitative research aimed to explore the perspectives of Muslim adolescents on smoking habits as a reference for developing effective prevention programs. Methods Three focus group discussions involving 24 junior high school male students (mean age = 13.75 years) were the main source of data for this phenomenological qualitative study. The discussion guide was developed by the researchers based on the reviewed literature and validated by experts. The research findings were analyzed using an inductive content analysis with systematic steps based on the stages of qualitative data analysis. Results Adolescent perspectives on smoking were grouped into two themes: perception of smoking and smoking-related factors. The perception of smoking encompassed three sub-themes: smoking as a social habit, contradictive feelings, and the Islamic perspective. The smoking-related factors included peer pressure, the parents’ smoking status, masculinity and curiosity. The results indicated that adolescents consider smoking as a social habit but with contradictory feelings. The smoking habit was also stimulated by peer pressure, imitating parents who smoke, feeling masculine and curiosity. Conclusion We suggest that health professionals who are interested in developing smoking prevention programs in Indonesia should consider the adolescent perspective on smoking so that the prevention program will be more effective and appropriate for adolescents.


2021 ◽  
Vol 278 ◽  
pp. 116868
Author(s):  
Xiaoqin Feng ◽  
Jinhong Luo ◽  
Xiaocheng Wang ◽  
Wolong Xie ◽  
Jiao Jiao ◽  
...  

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