The Psychological Processes of Classic Psychedelics in the Treatment of Depression: A Systematic Review Protocol

2020 ◽  
Author(s):  
Lauren Johansen ◽  
Paul Liknaitzky ◽  
Maja Nedeljkovic ◽  
Lisa Mastin-Purcell ◽  
Greg Murray
Keyword(s):  
Systematic Review ◽  
Empirical Research ◽  
Data Extraction ◽  
Adult Population ◽  
Research Field ◽  
Assessment Tools ◽  
Depression Symptom ◽  
Psychological Processes ◽  
Current State ◽  
Review Protocol

Abstract BackgroundThere is currently renewed interest in the use of psychedelic therapy in the treatment of psychiatric disorders, including depression. The proposed systematic review will aim to identify, evaluate and summarise the psychological processes of change underlying psychedelic therapy for depression in the current literature and consider the implications these processes may have on the psychotherapy component of treatment. MethodsScopus, PsycINFO, PubMed and Web of Science databases will be searched using relevant terms. Studies will be included if they discuss the use of a classic psychedelic to treat depression symptomology in an adult population and report or propose psychological processes responsible for depression symptom change. Two authors will independently screen articles, complete quality assessment tools and conduct data extraction. Empirical and non-empirical research will be extracted and synthesised separately. A narrative synthesis approach will be used to report psychological processes identified in the literature. DiscussionThis systematic review will be the first to collate available evidence on the psychological processes associated with psychedelic therapy for depression. The preliminary nature of this research field is expected to result in the review having several limitations, namely heterogeneity between studies and a lack of empirical research. We intend for this review to present the current state of the literature, identify gaps and generate candidate variables that warrant further investigation. Systematic Review RegistrationPROSPERO CRD42020197202

scholarly journals Health insurance awareness and its uptake in India: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e043122
Author(s):  
Bhageerathy Reshmi ◽  
Bhaskaran Unnikrishnan ◽  
Shradha S Parsekar ◽  
Eti Rajwar ◽  
Ratheebhai Vijayamma ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Insurance ◽  
Data Extraction ◽  
Adult Population ◽  
Social Science Research ◽  
Healthcare Utilisation ◽  
Science Research ◽  
Research Network ◽  
Universal Healthcare ◽  
Government Websites

IntroductionHealth insurance is one of the important approaches that can help in boosting universal healthcare coverage through improved healthcare utilisation and financial protection. This objectives of this review are to identify various interventions implemented in India to promote awareness of health insurance, and to provide evidence for the effectiveness of such interventions on the awareness and uptake of health insurance by the resident Indian population.Methods and analysisA systematic review will be carried out based on the Cochrane handbook for systematic reviews of interventions. The review will include experimental and analytical observational studies that have included adult population (>18 years) in India. We will include any intervention, policy or programme that directly or indirectly affects awareness or uptake of health insurance. The following outcomes will be eligible to be included: awareness or health insurance literacy, attitude such as readiness to buy health insurance or decision making, uptake of health insurance, demand-side and supply-side factors for awareness of health insurance, and awareness as a factor for uptake and re-enrolment in health insurance. Databases such as MEDLINE (PubMed), Web of Science, Scopus, 3ie impact evaluation repository and Social Science Research Network will be searched from January 2010 to 15 July 2020. Additionally, important government websites and references of the included studies will be scanned to identify potential records. Three authors, independently, will carry out screening and data extraction. Studies will be categorised into quantitative and qualitative, and mixed-methods synthesis will be employed to analyse the findings.Ethics and disseminationThis review will be based on published studies and will not recruit human participants directly, therefore, ethical clearance is not applicable. We will disseminate the final review findings in a national or international conference and publish in a peer-reviewed journal.

Smart tourism destinations: a systematic review

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Sanaz Shafiee ◽  
Ali Rajabzadeh Ghatari ◽  
Alireza Hasanzadeh ◽  
Saeed Jahanyan
Keyword(s):  
Systematic Review ◽  
Synthesis Method ◽  
Research Field ◽  
Tourism Industry ◽  
Content Type ◽  
Online Databases ◽  
Review Protocol ◽  
Tourism Destinations ◽  
Qualitative Methodologies ◽  
Smart Tourism

Purpose This study aims to present a systematic review of smart tourism articles using a meta-synthesis method. Effective systematic reviews are essential for assisting stakeholders in implementing smart destinations. A systematic comprehension of studies on smart tourism is needed regarding the various components of smart tourism destinations, the metrics to map these components and their expected results. This study creates a framework for understanding how smart tourism destinations are theorized and developed. Design/methodology/approach Based on the meta-synthesis approach, this study collects, analyzes and synthesizes relevant research in smart tourism published in online databases by following a predetermined review protocol. Findings This study contributes to the discourse on smart tourism destinations by increasing the knowledge on the subject of smart destinations in regard to different categories. The selected articles were analyzed according to the proposed research questions and classified into three main categories: components, measurement and outputs. This study presents a new archetype for developing smart destinations and addresses efforts to bridge the gap in this research field. Practical implications This paper is noteworthy for stakeholders because it provides a comprehensive vision into the components that influence the growth of smart destinations. The advantage of the proposed methodology is that it creates a framework for understanding how smart destinations are theorized. Furthermore, it is helpful to use qualitative methodologies that efficiently allow the analysis of related literature and that also offer conceptual insights. Originality/value The findings provide information that can be used to help shape a fully conceptualized understanding of the smart destinations concept and can also prove important in providing a guide for policymakers and stakeholders in the tourism industry who seek to intelligently develop tourism destinations.

A Systematic Review of the Current State and Validity of Digital Assessment Tools for Psychiatry (Preprint)

2021 ◽  
Author(s):  
Nayra Anna Martin-Key ◽  
Benedetta Spadaro ◽  
Erin Funnell ◽  
Eleanor Jane Barker ◽  
Thea Sofie Schei ◽  
...  
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Depressive Disorder ◽  
Diagnostic Accuracy ◽  
Mental Healthcare ◽  
Risk Of Bias ◽  
Assessment Tools ◽  
Cochrane Library ◽  
Digital Assessment ◽  
Current State

BACKGROUND Given the role digital technologies are likely to play in the future of mental healthcare, there is a need for a comprehensive appraisal of the current state and validity (i.e., screening/diagnostic accuracy) of digital mental health assessments. OBJECTIVE To explore the current state and validity of question-and-answer-based digital tools for diagnosing and screening psychiatric conditions in adults. METHODS This systematic review was based on the Population, Intervention, Comparison, and Outcome (PICO) framework and was carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. MEDLINE, Embase, Cochrane Library, ASSIA, Web of Science Core Collection, CINAHL, and PsycINFO were systematically searched for articles published between 2005 and 2020. A descriptive evaluation of the study characteristics and digital solutions and a quantitative appraisal of the screening/diagnostic accuracy of the included tools was conducted. Risk of bias and applicability were assessed using the Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) guidelines. RESULTS A total of 25 studies met the inclusion criteria, with the most frequently evaluated conditions encompassing generalized anxiety disorder (GAD), major depressive disorder (MDD), and any depressive disorder. The majority of the studies employed digitized versions of existing pen-and-paper questionnaires, with findings revealing poor to excellent screening/diagnostic accuracy (sensitivity = 0.36-1.00, specificity = 0.37-1.00, AUC = 0.57-0.98) and a high risk of bias for most of the included studies. CONCLUSIONS The current state of the field of digital mental health tools is in its early stages and high-quality evidence is lacking. INTERNATIONAL REGISTERED REPORT RR2-10.2196/25382

scholarly journals Evidence on Respectful Maternity Care For Adolescents: A Systematic Review Protocol

2021 ◽  
Author(s):  
Helen H Habib ◽  
Jefferson Mwaisaka ◽  
Kwasi Torpey ◽  
Ernest Tei Maya ◽  
Augustine Ankomah
Keyword(s):  
Systematic Review ◽  
Quality Assessment ◽  
Maternity Care ◽  
Assessment Tool ◽  
Data Extraction ◽  
Respectful Maternity Care ◽  
Great Promise ◽  
Systematic Review Protocol ◽  
Health And Human Rights ◽  
Review Protocol

Abstract Background: Intrapartum mistreatment of women is a globally rising public health and human rights phenomenon. The issue reportedly has severe maternal and neonatal outcomes including mortality, and generally leads to a decreased satisfaction with maternity care. Intrapartum mistreatment, despite being ubiquitous, indicates higher incidence among adolescent parturients who are simultaneously at a higher risk of maternal morbidity and mortality. Studies have suggested that Respectful Maternity Care (RMC) interventions reduce intrapartum mistreatment and improve clinical outcomes for women and neonates in general. However, evidence on the effect of RMC on adolescents is unclear. Hence the specific aim of this study is to synthesise the available evidence relating to the provision of RMC for adolescents during childbirth.Methods: The methodology of the proposed systematic review follows the procedural guideline depicted in the preferred reporting items for systematic review protocol. The review will include all observational and intervention studies conducted between January 1, 1990 and April 30, 2020. Electronic databases including MEDLINE, PubMed, ScienceDirect, Cochrane, CINAHL, PsycINFO, Scopus, Google Scholar, and Web of Science will be searched to retrieve available studies using the appropriate search strings. The search results will be appraised with Joanna Briggs Institute quality assessment tool. The selection of relevant studies, data extraction, and quality assessment of individual studies will be carried out by two independent authors. Results: A systematic narrative synthesis of the resultant studies will be done, and the relevant themes extracted. Findings will also be summarised in tables.Discussion: Respectful Maternity Care for adolescents holds great promise for improved maternal and neonatal care. However, there is a gap in knowledge on the interventions that work and the extent of their effectiveness. Findings from this study will be beneficial in improving Adolescents Sexual and Reproductive Health and Rights (ASRHR) and reducing maternal mortality, especially for adolescents.Systematic review registration: PROSPERO (Submitted 21 August 2020)

scholarly journals Prevalence and predictors of medication non-adherence among patients with multimorbidity: A systematic review protocol

2019 ◽  
Vol 2 ◽  
pp. 29
Author(s):  
Louise Foley ◽  
James Larkin ◽  
Richard Lombard-Vance ◽  
Andrew W. Murphy ◽  
Gerard J. Molloy
Keyword(s):  
Systematic Review ◽  
Full Text ◽  
Chronic Conditions ◽  
Data Extraction ◽  
Meta Analysis ◽  
Intervention Development ◽  
Evidence Base ◽  
Multiple Chronic Conditions ◽  
Review Protocol ◽  
Form Quality

Introduction: Patients with multimorbidity are expected to adhere to complex medication regimens in order to manage their multiple chronic conditions. It has been reported the likelihood of adherence decreases as patients are prescribed more medications. Much medication adherence research to date is dominated by a single-disease focus, which is at odds with the rising prevalence of multimorbidity and may artificially underestimate the complexity of managing chronic illness. This review aims to describe the prevalence of medication non-adherence among patients with multimorbidity, and to identify potential predictors of non-adherence in this population. Methods: A systematic review will be conducted and reported according to PRISMA guidelines. PubMed, EMBASE, CINAHL and PsycINFO will be searched using a predefined search strategy from 2009–2019. Quantitative studies will be considered eligible for review if prevalence of medication non-adherence among adults with two or more chronic conditions is reported. Studies will be included in the review if available in English full text. Titles and abstracts will be screened by single review, with 20% of screening cross-checked by a second reviewer. Full-text articles will be screened by two independent reviewers, noting reasons for exclusions. Data extraction will be performed using a predefined extraction form. Quality and risk of bias assessment will be conducted using criteria for observational studies outlined by Sanderson et al. (2007). A narrative synthesis and, if feasible, meta-analysis will be conducted. Discussion: By exploring medication non-adherence from a multimorbidity perspective, the review aims to inform an evidence base for intervention development which accounts for the rising prevalence of patients with multiple chronic conditions.  Study registration: The systematic review is prospectively registered in PROSPERO (CRD42019133849); registered on 12 June 2019.

scholarly journals Systematic review protocol exploring the impact of the COVID-19 pandemic on the wellbeing of general practitioners

2021 ◽  
Author(s):  
Laura Jefferson ◽  
Su Golder ◽  
Veronica Dale ◽  
Holly Essex ◽  
Elizabeth McHugh ◽  
...  
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Quality Assessment ◽  
General Practitioners ◽  
Systematic Reviews ◽  
Assessment Tools ◽  
Systematic Review Protocol ◽  
Health And Wellbeing ◽  
Review Protocol ◽  
The Impact

Background Over recent years chronic stress and burnout have been reported by doctors working in general practice in the UK NHS and internationally. The COVID-19 pandemic has changed general practitioners working lives; adding potential pressures from avoiding infection and addressing pent-up demand for care, but also changing processes such as rapidly taking up remote consultations. To date, there has been a focus on exploring the impact of the pandemic on the wellbeing of hospital clinicians. No registered systematic reviews currently focus on exploring the impact of the pandemic on the mental health and wellbeing of general practitioners. Aims and objectives To synthesise the current international evidence base exploring the impact of COVID-19 on the mental health and wellbeing of general practitioners, and which factors are associated with their reported mental health and wellbeing during the pandemic. Methods In this paper we report a systematic review protocol, following PRISMA guidance. In our search strategy we will identify primary research studies or systematic reviews exploring the mental health and wellbeing of general practitioners during the COVID-19 pandemic in four databases (MEDLINE, Embase, PsychInfo and Medrxiv) and Google Scholar. We will hand-search reference lists and grey literature. Two reviewers will undertake all stages including study selection, data extraction and quality assessment, with arbitration by a third reviewer where necessary. We will use standardised quality assessment tools to ensure transparency and reduce bias in quality assessment. Depending on the quality of included studies, we may undertake a sensitivity analysis by excluding studies from narrative synthesis that are rated as low quality using the checklists. We will describe the findings across studies using narrative thematic data synthesis, and if sufficiently homogenous data are identified, we will pool quantitative findings through meta-analysis.

scholarly journals Pharmacogenetics of Type 2 diabetes mellitus: A Systematic Review Protocol (Preprint)

2019 ◽  
Author(s):  
Hamid Reza Aghaei Meybodi ◽  
Negar Sarhangi ◽  
Anoosh Naghavi ◽  
Marzieh Rahbaran ◽  
Maryam Hassani Doabsari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Data Extraction ◽  
Relevant Information ◽  
Risk Of Bias ◽  
Cochrane Database ◽  
Registration Number ◽  
Newcastle Ottawa Scale ◽  
Review Protocol

UNSTRUCTURED The objective of this systematic review is to determine the effect of genetic variants that associate with antidiabetic medications and their efficacy and toxicity in T2DM patients. The understanding may allow interventions for improving management of T2DM and later systematically evaluated in more in-depth studies. We will have performed a comprehensive search using PubMed, Scopus, EMBASE, Web of Sciences and Cochrane database from 1990 to 2018. Relevant journals and references of all included studies will be hand searched to find the additional studied. Eligible studies such as pharmacogenetics studies in terms of drug response and toxicity in the type 2 diabetes patients and performed just on human will be included. Data extraction and quality assessment will be carried out by two independent reviewers and disagreements will be resolved through third expert reviewer. Risk of bias will be assessed with the Cochrane Risk of Bias tool for randomized studies and Newcastle-Ottawa Scale (NOS) for observational Studies. Narrative synthesis will be conducted by the combination of key findings. The results of this study will be submitted to a peer-reviewed journal for publication and also presented at PROSPERO. We expect this review will provide highly relevant information for clinicians, pharmaceutical industry that will benefit from the summary of the best available data regarding the efficacy of antidiabetic medication in the aspect of pharmacogenetics. PROSPERO Registration number (CRD42018104843)

Factors associated with dementia-related stigma and associated domains in adolescents: A Systematic Review Protocol v1

2021 ◽  
Author(s):  
Mrs Esra Hassan ◽  
Prof Naji Tabet ◽  
n.farina not provided
Keyword(s):  
Systematic Review ◽  
Data Extraction ◽  
Future Research ◽  
Factors Associated ◽  
Related Stigma ◽  
Review Protocol ◽  
Learning Software ◽  
Meta Analyses ◽  
Theses And Dissertations ◽  
Appraisal Tool

Background: To develop evidence-based anti-stigma programmes for adolescents, underlying factors that drive dementia-related stigma in adolescents need to be captured. However, it is unclear which factors play a role in dementia attitude formation in adolescents. This is a protocol for a systematic review that will seek to identify factors associated with dementia attitudes in adolescents (10-18 years old). Methods: A systematic search strategy will be used to identify observational data in which factors are associated with dementia-related stigma and associated domains (e.g. attitudes, beliefs, perceptions). Systematic searches for articles will be conducted in the following databases: PubMed, PsycInfo, Web of Science, SCOPUS and Open Access Theses and Dissertations. Titles and abstracts will be screened with the assistance of machine learning software (ASReview), prior to reviewing full texts. Following data extraction, quality assessment of study and risk of bias will be assessed using the mixed methods appraisal tool (MMAT). The protocol is written in line with the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocol (PRISMA-P) guidelines. Results: Descriptive data of the studies will be reported in tables and summarised narratively and split into thematic headings guided by the results of the systematic review. Identifying which factors are implicated in attitudes towards people living with dementia will allow researchers to be better informed in which factors may be a useful target for more tailored and effective dementia related anti-stigma-initiatives. Discussion: The findings from this systematic review will help guide future research to identify groups that may be at the greatest risk of developing stigmatising attitudes and potential targets for future intervention.

scholarly journals How does the intensity of physical therapy affect the Gross Motor Function Measure (GMFM-66) total score in children with cerebral palsy? A systematic review protocol

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e036630
Author(s):  
Mary Rahlin ◽  
Burris Duncan ◽  
Carol L Howe ◽  
Heidi L Pottinger
Keyword(s):  
Systematic Review ◽  
Motor Function ◽  
Data Extraction ◽  
Systematic Review Protocol ◽  
Gross Motor ◽  
Gross Motor Function ◽  
Gross Motor Function Measure ◽  
Children With Cerebral Palsy ◽  
Review Protocol ◽  
Function Measure

IntroductionIntensive physical therapy (PT) interventions administered to children with cerebral palsy (CP) have received a significant amount of attention in published literature. However, there is considerable variability in therapy intensity among studies and notable lack of information on optimal intervention dosing. This makes it difficult for clinicians to use evidence to inform practice. Many studies use the Gross Motor Function Measure (GMFM-66) to assess functional progress in children with CP. The purpose of this systematic review will be to identify the GMFM-66 change score reported in published studies, with outcomes based on intervention intensity. Whether the type of PT intervention, child’s age, and Gross Motor Function Classification System level influence the GMFM-66 scores will be also assessed.Methods and analysisThis systematic review protocol was developed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) 2015 checklist. In March 2018, nine databases (PubMed, Ovid MEDLINE, Cochrane Library, Embase, Scopus, Web of Science, CINAHL, ClinicalTrials.gov, and REHABDATA) were searched for controlled clinical trials and single-subject design studies of PT interventions of any kind and intensity that used the GMFM-66 as an outcome measure for children with CP, age up to 18 years. Two authors independently reviewed the titles and abstracts and arrived at consensus on paper selection for a full-text review. The same process was used for a full-text article screening based on further detailed inclusion criteria, with a final selection made for those suitable for data extraction. Prior to commencement of data extraction, all searches will be updated, and new results re-screened.Ethics and disseminationThis study will involve a systematic review of published articles and no primary data collection. Therefore, no ethical approval will be necessary. Results will be disseminated in a peer-reviewed publication and presented at scientific conferences.PROSPERO registration numberCRD42020147669

scholarly journals Acupuncture for patients with vascular dementia: a systematic review protocol

BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e019066 ◽  
Author(s):  
Yang Ye ◽  
Ling-Yong Xiao ◽  
Yi-Hua Liu ◽  
Jing-Wen Yang ◽  
Chao-Qun Yan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vascular Dementia ◽  
Data Extraction ◽  
Evaluation Study ◽  
Biomedical Literature ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Systematic Review Protocol ◽  
China National Knowledge Infrastructure ◽  
Review Protocol

IntroductionThis systematic review protocol aims to provide the methods used to evaluate the effectiveness and safety of acupuncture therapy for treating vascular dementia.Methods and analysisThe following eight databases will be searched from inception to July 2017: Cochrane Central Register of Controlled Trials, PubMed, MEDLINE, EMBASE, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Database and Wanfang Database. All randomised controlled trials in English or Chinese related to acupuncture for vascular dementia will be included. Outcomes will include change in cognitive function and activities of daily living. The incidence of adverse events will be assessed for safety evaluation. Study inclusion, data extraction and quality assessment will be performed independently by two reviewers. Assessment of risk of bias and data synthesis will be performed using Review Manager software.Ethics and disseminationEthics approval is not required because individual patient data are not included. The findings of this systematic review will be disseminated through peer-reviewed publication or conference presentations.PROSPERO registration numberCRD42017071820.

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