scholarly journals THETA: Machine-learning Algorithm for Evaluating Hybrid Operation Theater Entry of Trauma Patients

2020 ◽  
Author(s):  
Atsushi Senda ◽  
Akira Endo ◽  
Takahiro Kinoshita ◽  
Yasuhiro Otomo
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Regression Model ◽  
Web Application ◽  
Logistic Regression Model ◽  
Learning Algorithm ◽  
Regression Tree ◽  
Operating Rooms ◽  
Classification And Regression Tree ◽  
Trauma Patients

Abstract Background The clinical benefits of hybrid operating rooms are recognized globally. However, appropriate conditions for entry into such rooms must be urgently established, because they exclusively benefit few patients under severe trauma while requiring a significant amount of resources. This paper presents an algorithm to triage trauma patients into a hybrid operating room. Methods This retrospective observational study was conducted using the Japan Trauma Data Bank database comprising information collected between January 2004 and December 2018. A machine-learning-based triage algorithm is developed using the baseline demographics, injury mechanisms, and vital signs obtained from the database. The analysis dataset comprised information regarding 117,771 trauma patients with abbreviated injury scale (AIS) > 3. The performance of the proposed model was compared against those of other statistical models (logistic regression and classification and regression tree [CART] models) while considering the status quo entry condition (systolic blood pressure < 90 mmHg). Results The proposed trauma hybrid-suite entry algorithm (THETA) outperforms other algorithms (PR-AUC: THETA [0.59], logistic regression model [0.22], and CART [0.20]; AUROC: THETA [0.93], logistic regression model [0.88], and CART [0.86]), thereby facilitating appropriate triaging of patients who would potentially benefit from resuscitation performed using angiographic percutaneous techniques and operative resuscitation suites. Conclusions An accurate machine-learning-based algorithm is developed to triage patient entry into hybrid operating rooms via a web application, thereby enabling emergency doctors to utilize limited medical resources more efficiently.

scholarly journals A Machine-Learning Model Based on Morphogeometric Parameters for RETICS Disease Classification and GUI Development

2020 ◽  
Vol 10 (5) ◽  
pp. 1874 ◽  
Author(s):  
José M. Bolarín ◽  
F. Cavas ◽  
J.S. Velázquez ◽  
J.L. Alió
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Regression Model ◽  
Web Application ◽  
High Performance ◽  
Logistic Regression Model ◽  
Early Stage ◽  
Disease Classification ◽  
Multivariate Logistic Regression Model ◽  
Detection Model

This work pursues two objectives: defining a new concept of risk probability associated with suffering early-stage keratoconus, classifying disease severity according to the RETICS (Thematic Network for Co-Operative Research in Health) scale. It recruited 169 individuals, 62 healthy and 107 keratoconus diseased, grouped according to the RETICS classification: 44 grade I; 18 grade II; 15 grade III; 15 grade IV; 15 grade V. Different demographic, optical, pachymetric and eometrical parameters were measured. The collected data were used for training two machine-learning models: a multivariate logistic regression model for early keratoconus detection and an ordinal logistic regression model for RETICS grade assessments. The early keratoconus detection model showed very good sensitivity, specificity and area under ROC curve, with around 95% for training and 85% for validation. The variables that made the most significant contributions were gender, coma-like, central thickness, high-order aberrations and temporal thickness. The RETICS grade assessment also showed high-performance figures, albeit lower, with a global accuracy of 0.698 and a 95% confidence interval of 0.623–0.766. The most significant variables were CDVA, central thickness and temporal thickness. The developed web application allows the fast, objective and quantitative assessment of keratoconus in early diagnosis and RETICS grading terms.

scholarly journals Using Machine Learning Algorithm to Describe the Connection between the Types and Characteristics of Music Signal

Complexity ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Bo Sun
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Learning Algorithm ◽  
Machine Learning Algorithms ◽  
Classification Model ◽  
Machine Learning Algorithm ◽  
Music Classification ◽  
Music Signal

Music classification is conducive to online music retrieval, but the current music classification model finds it difficult to accurately identify various types of music, which makes the classification effect of the current music classification model poor. In order to improve the accuracy of music classification, a music classification model based on multifeature fusion and machine learning algorithm is proposed. First, we obtain the music signal, and then extract various features from the classification of the music signal, and use machine learning algorithms to describe the type of music signal and the relationship between the features. The music classifier and deep belief network machine learning models in shallow logistic regression are established, respectively. Experiments were designed for these two models to verify the applicability of the model for music classification. By comparing the experimental results, it is found that the classification accuracy of the deep confidence network model is higher than that of the logistic regression model, but the number of iterations needed for its accuracy to converge is also higher than that of the logistic regression model. Compared with other current music classification models, this model reduces the time of constructing music classifier, speeds up the speed of music classification, and can identify various types of music with high precision. The accuracy of music classification is obviously improved, which verifies the superiority of this music classification model.

scholarly journals Machine-Learning vs. Expert-Opinion Driven Logistic Regression Modelling for Predicting 30-Day Unplanned Rehospitalisation in Preterm Babies: A Prospective, Population-Based Study (EPIPAGE 2)

2021 ◽  
Vol 8 ◽  
Author(s):  
Robert A. Reed ◽  
Andrei S. Morgan ◽  
Jennifer Zeitlin ◽  
Pierre-Henri Jarreau ◽  
Héloïse Torchin ◽  
...  
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Random Forest ◽  
Regression Model ◽  
Expert Opinion ◽  
Logistic Regression Model ◽  
Population Based ◽  
Regression Modelling ◽  
Preterm Babies ◽  
Logistic Regression Modelling

Introduction: Preterm babies are a vulnerable population that experience significant short and long-term morbidity. Rehospitalisations constitute an important, potentially modifiable adverse event in this population. Improving the ability of clinicians to identify those patients at the greatest risk of rehospitalisation has the potential to improve outcomes and reduce costs. Machine-learning algorithms can provide potentially advantageous methods of prediction compared to conventional approaches like logistic regression.Objective: To compare two machine-learning methods (least absolute shrinkage and selection operator (LASSO) and random forest) to expert-opinion driven logistic regression modelling for predicting unplanned rehospitalisation within 30 days in a large French cohort of preterm babies.Design, Setting and Participants: This study used data derived exclusively from the population-based prospective cohort study of French preterm babies, EPIPAGE 2. Only those babies discharged home alive and whose parents completed the 1-year survey were eligible for inclusion in our study. All predictive models used a binary outcome, denoting a baby's status for an unplanned rehospitalisation within 30 days of discharge. Predictors included those quantifying clinical, treatment, maternal and socio-demographic factors. The predictive abilities of models constructed using LASSO and random forest algorithms were compared with a traditional logistic regression model. The logistic regression model comprised 10 predictors, selected by expert clinicians, while the LASSO and random forest included 75 predictors. Performance measures were derived using 10-fold cross-validation. Performance was quantified using area under the receiver operator characteristic curve, sensitivity, specificity, Tjur's coefficient of determination and calibration measures.Results: The rate of 30-day unplanned rehospitalisation in the eligible population used to construct the models was 9.1% (95% CI 8.2–10.1) (350/3,841). The random forest model demonstrated both an improved AUROC (0.65; 95% CI 0.59–0.7; p = 0.03) and specificity vs. logistic regression (AUROC 0.57; 95% CI 0.51–0.62, p = 0.04). The LASSO performed similarly (AUROC 0.59; 95% CI 0.53–0.65; p = 0.68) to logistic regression.Conclusions: Compared to an expert-specified logistic regression model, random forest offered improved prediction of 30-day unplanned rehospitalisation in preterm babies. However, all models offered relatively low levels of predictive ability, regardless of modelling method.

scholarly journals Prediction of perinatal death using machine learning models: a birth registry-based cohort study in northern Tanzania

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e040132
Author(s):  
Innocent B Mboya ◽  
Michael J Mahande ◽  
Mohanad Mohammed ◽  
Joseph Obure ◽  
Henry G Mwambi
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Perinatal Death ◽  
Learning Models ◽  
Net Benefit ◽  
Birth Registry ◽  
Perinatal Deaths ◽  
Machine Learning Models

ObjectiveWe aimed to determine the key predictors of perinatal deaths using machine learning models compared with the logistic regression model.DesignA secondary data analysis using the Kilimanjaro Christian Medical Centre (KCMC) Medical Birth Registry cohort from 2000 to 2015. We assessed the discriminative ability of models using the area under the receiver operating characteristics curve (AUC) and the net benefit using decision curve analysis.SettingThe KCMC is a zonal referral hospital located in Moshi Municipality, Kilimanjaro region, Northern Tanzania. The Medical Birth Registry is within the hospital grounds at the Reproductive and Child Health Centre.ParticipantsSingleton deliveries (n=42 319) with complete records from 2000 to 2015.Primary outcome measuresPerinatal death (composite of stillbirths and early neonatal deaths). These outcomes were only captured before mothers were discharged from the hospital.ResultsThe proportion of perinatal deaths was 3.7%. There were no statistically significant differences in the predictive performance of four machine learning models except for bagging, which had a significantly lower performance (AUC 0.76, 95% CI 0.74 to 0.79, p=0.006) compared with the logistic regression model (AUC 0.78, 95% CI 0.76 to 0.81). However, in the decision curve analysis, the machine learning models had a higher net benefit (ie, the correct classification of perinatal deaths considering a trade-off between false-negatives and false-positives)—over the logistic regression model across a range of threshold probability values.ConclusionsIn this cohort, there was no significant difference in the prediction of perinatal deaths between machine learning and logistic regression models, except for bagging. The machine learning models had a higher net benefit, as its predictive ability of perinatal death was considerably superior over the logistic regression model. The machine learning models, as demonstrated by our study, can be used to improve the prediction of perinatal deaths and triage for women at risk.

P5710Clinical applications of machine learning for prediction of incident atrial fibrillation from the general population: a nationwide cohort study

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
I.-S Kim ◽  
P S Yang ◽  
H T Yu ◽  
T H Kim ◽  
J S Uhm ◽  
...  
Keyword(s):  
Machine Learning ◽  
Atrial Fibrillation ◽  
Logistic Regression ◽  
General Population ◽  
Regression Model ◽  
National Health ◽  
Logistic Regression Model ◽  
Learning System ◽  
Health Examination ◽  
Clinical Variables

Abstract Background To evaluate the ability of machine learning algorithms to predict incident atrial fibrillation (AF) from the general population using health examination items. Methods We included 483,343 subjects who received national health examinations from the Korean National Health Insurance Service-based National Sample Cohort (NHIS-NSC). We trained deep neural network model (DNN) of a deep learning system and decision tree model (DT) of a machine learning system using clinical variables and health examination items (including age, sex, body mass index, history of heart failure, hypertension or diabetes, baseline creatinine, and smoking and alcohol intake habits) to predict incident AF using a training dataset of 341,771 subjects constructed from the NHIS-NSC database. The DNN and DT were validated using an independent test dataset of 141,572 remaining subjects. C-indices of DNN and DT for prediction of incident AF were compared with that of conventional logistic regression model. Results During 1,874,789 person·years (mean±standard-deviation age 47.7±14.4 years, 49.6% male), 3,282 subjects with incident AF were observed. In the validation dataset, 1,139 subjects with incident AF were observed. The c-indices of the DNN and DT for incident AF prediction were 0.828 [0.819–0.836] and 0.835 [0.825–0.844], and were significantly higher (p<0.01) than conventional logistic regression model (c-index=0.789 [0.784–0.794]). Conclusions Application of machine learning using simple clinical variables and health examination items was helpful to predict incident AF in the general population. Prospective study is warranted to construct an individualized precision medicine.

scholarly journals Early Prediction of the Carbapenem Resistance Gram-negative Bacteria Carriage in Intensive Care Unit using Machine-Learning

2020 ◽  
Author(s):  
Qiqiang Liang ◽  
Qinyu Zhao ◽  
Xin Xu ◽  
Yu Zhou ◽  
Man Huang
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Carbapenem Resistance ◽  
Multivariate Logistic Regression Model ◽  
Gram Negative Bacteria ◽  
Multivariate Logistic Regression ◽  
Gram Negative ◽  
Better Than

Abstract Background The prevention and control of carbapenem-resistance gram-negative bacteria (CR-GNB) is the difficulty and focus for clinicians in the intensive care unit (ICU). This study construct a CR-GNB carriage prediction model in order to predict the CR-GNB incidence in one week. Methods The database is comprised of nearly 10,000 patients. the model is constructed by the multivariate logistic regression model and three machine learning algorithms. Then we choose the optimal model and verify the accuracy by daily predicted and recorded the occurrence of CR-GNB of all patients admitted for 4 months. Results There are 1385 patients with positive CR-GNB cultures and 1535 negative patients in this study. Forty-five variables have statistical significant differences. We include the 17 variables in the multivariate logistic regression model and build three machine learning models for all variables. In terms of accuracy and the area under the receiver operating characteristic (AUROC) curve, the random forest is better than XGBoost and multivariate logistic regression model, and better than decision tree model (accuracy: 84% >82%>81%>72%), (AUROC: 0.9089 > 0.8947 ≈ 0.8987 > 0.7845). In the 4-month prospective study, 81 cases were predicted to be positive in CR-GNB culture within 7 days, 146 cases were predicted to be negative, 86 cases were positive, and 120 cases were negative, with an overall accuracy of 84% and AUROC of 91.98%. Conclusions Prediction models by machine learning can predict the occurrence of CR-GNB colonization or infection within a week period, and can real-time predict and guide medical staff to identify high-risk groups more accurately.

scholarly journals Root for a Phishing Page using Machine Learning

2019 ◽  
Vol 9 (1) ◽  
pp. 1692-1695
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model

Phishing alludes of the mimicking of the first website. To infiltrate this sort of con,the correspondence claims will a chance to be starting with an official illustrative of a website alternately another institutional Furthermore starting with the place an individual need a probable benefits of the business with. (eg. PayPal,Amazon,UPS,Bank for america etc). It focuses those vunariblities Toward method for pop ups ,ads,fake login pages and so on. Web clients are pulled in Eventually Tom's perusing method for leveraging their trust on acquire their delicate data for example, such that usernames,passwords,account numbers or other data with open record on acquire loans or purchase all the merchandise through e-commerce locales. Upto 5% for clients appear on make lured under these attacks,so it might remain calm gainful for scammers-many about whom who send a large number for trick e-mails An day. In this system,we offer an answer with this issue Toward settling on those client mindful of such phishing exercises Eventually Tom's perusing identifying the trick joins Furthermore urls Toward utilizing the blending of the The majority powerful calculations for machine learning, Concerning illustration An result, we infer our paper with correctness from claiming 98.8% What's more mix from claiming 26 offers. The best algorithm being ,the logistic regression model.

scholarly journals Machine learning-based prediction model for responses of bDMARDs in patients with rheumatoid arthritis and ankylosing spondylitis

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Seulkee Lee ◽  
Seonyoung Kang ◽  
Yeonghee Eun ◽  
Hong-Hee Won ◽  
Hyungjin Kim ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Machine Learning ◽  
Logistic Regression ◽  
Ankylosing Spondylitis ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Prediction Performance ◽  
Learning Models ◽  
Independent Test ◽  
Machine Learning Models

Abstract Background Few studies on rheumatoid arthritis (RA) have generated machine learning models to predict biologic disease-modifying antirheumatic drugs (bDMARDs) responses; however, these studies included insufficient analysis on important features. Moreover, machine learning is yet to be used to predict bDMARD responses in ankylosing spondylitis (AS). Thus, in this study, machine learning was used to predict such responses in RA and AS patients. Methods Data were retrieved from the Korean College of Rheumatology Biologics therapy (KOBIO) registry. The number of RA and AS patients in the training dataset were 625 and 611, respectively. We prepared independent test datasets that did not participate in any process of generating machine learning models. Baseline clinical characteristics were used as input features. Responders were defined as those who met the ACR 20% improvement response criteria (ACR20) and ASAS 20% improvement response criteria (ASAS20) in RA and AS, respectively, at the first follow-up. Multiple machine learning methods, including random forest (RF-method), were used to generate models to predict bDMARD responses, and we compared them with the logistic regression model. Results The RF-method model had superior prediction performance to logistic regression model (accuracy: 0.726 [95% confidence interval (CI): 0.725–0.730] vs. 0.689 [0.606–0.717], area under curve (AUC) of the receiver operating characteristic curve (ROC) 0.638 [0.576–0.658] vs. 0.565 [0.493–0.605], F1 score 0.841 [0.837–0.843] vs. 0.803 [0.732–0.828], AUC of the precision-recall curve 0.808 [0.763–0.829] vs. 0.754 [0.714–0.789]) with independent test datasets in patients with RA. However, machine learning and logistic regression exhibited similar prediction performance in AS patients. Furthermore, the patient self-reporting scales, which are patient global assessment of disease activity (PtGA) in RA and Bath Ankylosing Spondylitis Functional Index (BASFI) in AS, were revealed as the most important features in both diseases. Conclusions RF-method exhibited superior prediction performance for responses of bDMARDs to a conventional statistical method, i.e., logistic regression, in RA patients. In contrast, despite the comparable size of the dataset, machine learning did not outperform in AS patients. The most important features of both diseases, according to feature importance analysis were patient self-reporting scales.

scholarly journals Prediction of all-cause mortality in coronary artery disease patients with atrial fibrillation based on machine learning models

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xinyun Liu ◽  
Jicheng Jiang ◽  
Lili Wei ◽  
Wenlu Xing ◽  
Hailong Shang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Atrial Fibrillation ◽  
Coronary Artery Disease ◽  
Logistic Regression ◽  
Regression Model ◽  
Logistic Regression Model ◽  
Support Vector ◽  
Vector Machines ◽  
All Cause Mortality ◽  
Artery Disease

Abstract Background Machine learning (ML) can include more diverse and more complex variables to construct models. This study aimed to develop models based on ML methods to predict the all-cause mortality in coronary artery disease (CAD) patients with atrial fibrillation (AF). Methods A total of 2037 CAD patients with AF were included in this study. Three ML methods were used, including the regularization logistic regression, random forest, and support vector machines. The fivefold cross-validation was used to evaluate model performance. The performance was quantified by calculating the area under the curve (AUC) with 95% confidence intervals (CI), sensitivity, specificity, and accuracy. Results After univariate analysis, 24 variables with statistical differences were included into the models. The AUC of regularization logistic regression model, random forest model, and support vector machines model was 0.732 (95% CI 0.649–0.816), 0.728 (95% CI 0.642–0.813), and 0.712 (95% CI 0.630–0.794), respectively. The regularization logistic regression model presented the highest AUC value (0.732 vs 0.728 vs 0.712), specificity (0.699 vs 0.663 vs 0.668), and accuracy (0.936 vs 0.935 vs 0.935) among the three models. However, no statistical differences were observed in the receiver operating characteristic (ROC) curve of the three models (all P > 0.05). Conclusion Combining the performance of all aspects of the models, the regularization logistic regression model was recommended to be used in clinical practice.

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