scholarly journals Quality of Life and Its Correlates Among Clients Visiting Antiretroviral Therapy Clinics in Addis Ababa, Ethiopia

2021 ◽  
Author(s):  
Tariku Shimels ◽  
Gelila Bogale ◽  
Rodas Asrat ◽  
Teferi Gedif
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Addis Ababa ◽  
Multidisciplinary Treatment ◽  
Considerable Proportion ◽  
Health State ◽  
Cross Sectional ◽  
Eq Vas ◽  
Overall Health Status

Abstract Background: As a chronic illness with potential complications in physical, emotional, social, and economic aspects, HIV poses deterioration in patients’ quality of life.The aim of this study was to assess status of the functional and current quality of life, and associated factors among clients visiting ART clinics in Addis Ababa, Ethiopia. Methods: A multi-site cross-sectional study was conducted in August 2020. All adults with HIV and on active ART at least for 6 months earlier to the study period, and visiting the selected public health facilities were considered. Facilities were selected purposively, and clients were enrolled using a systematic random sampling technique after a proportion to size allocation. Data were collected using a modified and translated questionnaire of the EQ 5D and EQ-VAS. The analysis was done using SPSS v.26 for windows. Descriptive statistics and non-parametric inferential tests namely; Mann Whitney U test, Kruskal Wallis test, and Spearman’s correlation tests were carried out to test the presence of correlates with dependent variables. Ethical approval was sought from Saint Paul’s Hospital Millennium Medical College and Addis Ababa regional health bureau. Results: Out of 371 clients, the majority were from health centers (58%), aged 43 years or below (54%), males (63%), either with primary or secondary education (61%) and married (46.6%) while half were either government or private employees. Pain/discomfort and depression/anxiety were the dimensions most affected with predominance in the age group above 43. The mean score of EQ 5D index values was 0.87 (SD: ±0.05; 95% C.I; 0.86-0.87) and that of EQ-VAS was 81 (SD: ±15, 95% C.I: 80-83). About 38% and 43% of the clients showed an altered health state of any degree in functional and current overall status respectively. Comorbidity, history of current substance use, facility type, social support, and sleep disturbance showed a statistically significant correlation with the functional and current overall health status. Conclusion: A considerable proportion of clients have altered functional and overall health status with pain/discomfort and depression/anxiety most affected. Inclusion of multidisciplinary treatment for HIV and the highlighting of psychosocial issues that are likely amongst this group are warranted.

scholarly journals Quality of Life and Health Status of Adults With Congenital Heart Disease in Vietnam: A Cross-Sectional Study

2021 ◽  
Author(s):  
Thanh-Huong Truong ◽  
Ngoc-Thanh Kim ◽  
Mai-Ngoc Thi Nguyen ◽  
Doan-Loi Do ◽  
Hong Thi Nguyen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Congenital Heart Disease ◽  
Health Status ◽  
Congenital Heart ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
Sectional Study ◽  
Cross Sectional ◽  
Eq Vas

Abstract Background: Little is known about the quality of life (QOL) and health status of adults with congenital heart disease (CHD) in developing countries. Therefore, this study aimed to describe the QOL and health status of adults with CHD and investigate the association between QOL and biological and social characteristics of these patients in Vietnam.Methods: A cross-sectional study was performed among 109 adults with CHD, hospitalised in the Vietnam National Heart Institute, between June 2019 and December 2019. Validated instruments to assess QOL and health status describing patient-reported outcomes were used, including the EuroQOL-5 Dimensions-5 Level, Satisfaction with Life Scale and Hospital Anxiety and Depression Scale.Results: The overall mean scores on the EuroQOL-descriptive system (EQ-DS) and the EuroQOL visual analogue scale (EQ-VAS) were 0.792 (SD = 0.122, 95% confidence interval, CI 0.769–0.815) and 66.3 (SD = 12.5, 95% CI 63.9–68.7), respectively. Symptoms of anxiety and depression were common among adults with CHD (18.7%, n = 20 and 11%, n = 12; respectively). Stratified multivariate logistic regression revealed: poor QOL using the EQ-DS, and that anxiety related to suffering from a complex CHD/ pulmonary artery hypertension (PAH) (Odds Ratio, OR = 4.55, 95% CI: 1.26–16.4, p = 0.021 and OR = 4.19, 95% CI 1.2–14.56, p = 0.024; respectively); poor QOL using the EQ-VAS, anxiety, and depression related to being unemployed/ unstable employment (OR = 4.16, 95% CI 1.64–10.56, p = 0.003; OR = 3.63, 95% CI 1.23–10.72, p = 0.02 and OR = 7.68, 95% CI 2.09–28.25, p = 0.002; respectively); and life dissatisfaction related to being unmarried (OR = 4.63, 95% CI 1.2–17.86, p = 0.026).Conclusions: Adults with CHD in Vietnam experienced low QOL, and high levels of anxiety and depression. Poor QOL and psychological problems were related to being female, unmarried, low educational level, unemployed/ unstable employ, and complex CHD/ PAH.

scholarly journals Quality of Life and Health Status of Adults With Congenital Heart Disease in Vietnam: A Cross-sectional Study

2021 ◽  
Author(s):  
Thanh Huong Truong ◽  
Ngoc Thanh Kim ◽  
Mai Ngoc Thi Nguyen ◽  
Doan Loi Do ◽  
Hong Thi Nguyen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Congenital Heart ◽  
Cross Sectional Study ◽  
Pulmonary Artery Hypertension ◽  
Anxiety And Depression ◽  
Sectional Study ◽  
Cross Sectional ◽  
Eq Vas

Abstract Background: Little is known about the quality of life (QOL) and health status of adults with congenital heart disease (CHD) in developing countries. Therefore, this study aimed to describe the QOL and health status of adults with CHD and investigate the association between QOL and biological and social characteristics of these patients in Vietnam.Methods: A cross-sectional study was performed among 109 adults with CHD, hospitalised in the Vietnam National Heart Institute, between June 2019 and December 2019. Validated instruments to assess QOL and health status describing patient-reported outcomes were used, including the EuroQOL-5 Dimensions-5 Level, Satisfaction with Life Scale and Hospital Anxiety and Depression Scale. The data of QOL and health status were analysed using univariable and multivariable logistic regressions.Results: The overall mean scores on the EuroQOL-descriptive system (EQ-DS) and the EuroQOL visual analogue scale (EQ-VAS) were 79.2 (SD = 12.2, 95% confidence interval, CI: 76.9–81.5) and 66.3 (SD = 12.5, 95% CI: 63.9–68.7), respectively. Symptoms of anxiety and depression were common among adults with CHD (18.7%, n = 20 and 11%, n = 12; respectively). Stratified multivariate logistic regression revealed: poor QOL using the EQ-DS, and that anxiety related to suffering from a complex CHD or pulmonary artery hypertension (OR = 4.55; 95% CI: 1.26–16.4; p = 0.021 and OR = 4.19, 95% CI: 1.2–14.56; p = 0.024; respectively); poor QOL using the EQ-VAS and that anxiety and depression related to being unemployed or having an unstable employment (OR = 4.16, 95% CI: 1.64–10.56, p = 0.003; OR = 3.63, 95% CI: 1.23–10.72, p = 0.02 and OR = 7.68, 95% CI: 2.09–28.25, p = 0.002; respectively); and life dissatisfaction related to being unmarried (OR = 4.63; 95% CI: 1.2–17.86; p = 0.026).Conclusions: Adults with CHD in Vietnam experienced low QOL, and high levels of anxiety and depression. Poor QOL and psychological problems were related to being female, being unmarried, having low educational level, being unemployed or unstably employed, and having complex CHD or pulmonary artery hypertension.

Quality of life along the diabetes continuum: a cross-sectional view of health-related quality of life and general health status in middle-aged and older Finns

2014 ◽  
Vol 23 (7) ◽  
pp. 1935-1944 ◽  
Author(s):  
Saku Väätäinen ◽  
Sirkka Keinänen-Kiukaanniemi ◽  
Jouko Saramies ◽  
Hannu Uusitalo ◽  
Jaakko Tuomilehto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
General Health ◽  
Health Related Quality ◽  
General Health Status ◽  
Middle Aged ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

FOENIX-CCA2 quality of life data for futibatinib-treated intrahepatic cholangiocarcinoma (iCCA) patients with FGFR2 fusions/rearrangements.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 4097-4097
Author(s):  
Juan W. Valle ◽  
Antoine Hollebecque ◽  
Junji Furuse ◽  
Lipika Goyal ◽  
Funda Meric-Bernstam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Global Health ◽  
Global Health Status ◽  
Phase 2 ◽  
Life Data ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Eq Vas

4097 Background: In FOENIX-CCA2 (NCT02052778), a pivotal phase 2 study among iCCA patients (pts) with FGFR2 fusions/rearrangements, the highly selective, irreversible FGFR1–4 inhibitor futibatinib demonstrated a confirmed objective response rate of 41.7%, with a 9.7-month median duration of response. Adverse events were manageable with dosing modifications that did not adversely impact on response. We report outcomes for the preplanned analysis of Patient-Reported Outcomes (PROs) during futibatinib treatment as a secondary objective of FOENIX-CCA2. Methods: Pts enrolled in FOENIX-CCA2 had locally advanced/metastatic unresectable iCCA with FGFR2 fusions/rearrangements, ≥1 prior line of therapy (including gemcitabine/cisplatin) and ECOG PS 0-1. Pts received oral futibatinib 20 mg continuous QD dosing per 21-day cycle. PRO measures included EORTC-QLQ-C30 (1 global health, 5 functional, 9 symptom scales), EQ-5D-3L, and EQ visual analogue scale (VAS). PROs were collected at screening, cycles 2 and 4, every 3 cycles thereafter, and end of treatment. PRO data were evaluated up to cycle 13, the last visit before data were missing for >50% of the PRO population (PRO primary assessment time point). Results: 92/103 (89.3%) pts enrolled had PRO completion data at baseline and a minimum of 1 follow-up assessment (median age 58 y, 56.5% female), with 48 pts having PRO data at cycle 13. At baseline, mean (SD) EORTC QLQ-C30 global health status score was 70.1 (19.4) and EQ VAS score 71.7 (20.3). Mean EORTC QLQ-C30 global health status scores were maintained from baseline to cycle 13, corresponding to 9.0 months on treatment, with no clinically meaningful (≥10-point) changes in individual functional measures (Table). EORTC QLQ-C30 scores across individual symptom measures were also stable from baseline through cycle 13; only constipation showed an average of 10.0-point worsening at only cycle 4. Mean EQ VAS scores were sustained from baseline to cycle 13 (mean change ranging -1.8 to +4.8 across cycles), with values maintained within the population norm range from across 20 countries. Conclusions: Quality of life data from the phase 2 FOENIX-CCA2 trial show that physical, cognitive and emotional functioning, and overall health status were maintained among pts with advanced iCCA receiving futibatinib. Clinical trial information: NCT02052778. [Table: see text]

scholarly journals THE IMPACT OF MEDICATION ADHERENCE ON HEALTH-RELATED QUALITY OF LIFE OF DIABETIC PATIENTS IN THE KINGDOM OF SAUDI ARABIA: FINDINGS FROM A CROSS-SECTIONAL STUDY

2020 ◽  
Vol 17 (34) ◽  
pp. 867-873
Author(s):  
Dhfer ALSHAYBAN ◽  
Royes JOSEPH
Keyword(s):  
Quality Of Life ◽  
Medication Adherence ◽  
Cross Sectional Study ◽  
P Value ◽  
Diabetic Patients ◽  
Health State ◽  
Cross Sectional ◽  
Related Quality ◽  
The Impact

Diabetes is a common chronic disease that is considered as one of the fastest-growing health problems in the world. Adherence to medications could be an important factor in reducing these complications and improving the quality of life. The purpose of this research was to assess the impact of treatment adherence on health-related quality of life in patients with type 2 diabetes. A multicenter cross-sectional study was carried out among 368 diabetes patients. General Medication Adherence Scale was used to assess the adherence level and EuroQol-5D to assess the quality of life. The results show that 19%, 21%, and 23% of patients had maintained low medication adherence due to patient’s intentional or unintentional behavior due to additional diseases or pills burden and due to financial constraints, respectively. Overall, 43% (n=162) participants had maintained high medication adherence, and 37% (n=138) had maintained low medication adherence to antidiabetic drugs. Nearly one-third (31%) of patients with high overall adherence had perfect health state in comparison with 4% among patients with low adherence. Further, the lower proportion (21%) of patients with high overall adherence had perfect health state in comparison with that among patients with low adherence (34%). In addition to the overall adherence, the association was statistically significant for the domains related to non-adherence due to the patient’s intentional or unintentional behavior (p-value 0.001) and non-adherence due to additional diseases or pills burden (p-value 0.001) after taking into account of socio-demographic and clinical characteristics. In conclusion, the findings suggest that the policymakers should establish an intervention to improve adherence to diabetic treatment, and thus improve the quality of life for the type 2 diabetic patients.

Impact of musculoskeletal disorders on quality of life of patients visiting tertiary care hospital.

2021 ◽  
pp. 1-11
Author(s):  
Shah Khalid ◽  
Sayed Zulfiqar Ali Shah ◽  
Abid Ali Khalil ◽  
Ihsan Ullah
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Musculoskeletal Disorders ◽  
Teaching Hospital ◽  
Adhesive Capsulitis ◽  
Care Hospital ◽  
Cross Sectional ◽  
Quality Of Life Scale ◽  
The Impact

Abstract Objective: To determine the impact of musculoskeletal disorders on quality of life of patients visiting Khyber Teaching Hospital, Peshawar. Method and Material: A cross sectional survey conducted in Khyber Teaching Hospital, Peshawar from September 2018 to March 2019 using a validated EQ-5D quality of life scale. The survey questionnaire was attended by 377 respondents having variety of musculoskeletal disorders (MSDs). EQ-5D can be effectively used for assessing the quality of life and health status using the VAS pain scale. Results: There were total 377 respondents. Mean age of the participants was 35.9 ± 12.5 years. Out of 377 participants, 204 (54.1%) were male, while 173 (45.9%) were female. Muscular weakness was the most commonly encountered problem (40.6%), followed by muscle stiffness (13.0%) and adhesive capsulitis (10.3%). The remaining respondents were having different kinds of MSDs. Patients with MSDs were having significantly moderately low score on EQ-5D. Conclusion: The finding of this study suggests that MSDs have negative impact on quality of life and health status of the sufferers. Individuals having any sort of MSDs should seek proper care in order to improve their quality of life, health status and work performance. Key words: Musculoskeletal Diseases, Health, Quality of Life, visual analog scales, Cross Sectional Studies. Continuou....

Does it really matter where you live? A panel data multilevel analysis of Swedish municipality-level social capital on individual health-related quality of life

2006 ◽  
Vol 1 (3) ◽  
pp. 209-235 ◽  
Author(s):  
M. Kamrul Islam ◽  
Juan Merlo ◽  
Ichiro Kawachi ◽  
Martin Lindström ◽  
Kristina Burström ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Capital ◽  
Health Status ◽  
Panel Data ◽  
Health State ◽  
Health Related Quality ◽  
Individual Health ◽  
Related Quality ◽  
Health Related

We test whether individual health status is related to area-level social capital measured by rates of voting participation in municipal political elections, controlling for personal characteristics, where health status is measured by mapping responses to interview survey questions into the generic health-related quality of life measure (HRQoL) the EQ-5D in order to derive the health state scores. The analysis is based on unbalanced panel data from Statistic Sweden's Survey of Living Conditions (the ULF survey) and a 3-level multilevel regression analysis, where level 1 consists of a total of 31,585 observations for 24,419 individuals at level 2 nested within 275 Swedish municipalities at level 3. We find that the health state scores increase significantly with municipality election rates. This result is robust to a number of measurement and specification issues explored in a sensitivity analysis. However, almost all variation in health status exists across individuals (more than 98%), which demonstrates that even if social capital (and other contextual variables) may be significant it is of less importance, at least at the municipality level in Sweden.

Quality of Life in Patients with Thalassemia.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 3786-3786
Author(s):  
Zahra Pakbaz ◽  
Marsha Treadwell ◽  
Robert Yamashita2 ◽  
Drucilla Foote ◽  
Elliott Vichinsky
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Thalassemia Major ◽  
Essential Information ◽  
Health Impairment ◽  
Severe Impairment ◽  
Multiple Domains ◽  
The Impact ◽  
Overall Health Status

Abstract Introduction: Thalassemia patients have experienced a dramatic increase in lifespan secondary to improved and more complicated therapy. The impact of the disease and its treatment on quality of life is largely unknown. Determining the degree of health impairment as perceived by the patient is essential information needed to recommend suitable therapy. Factors that affect the quality of life of thalassemia major patients may differ from thalassemia intermedia patients. Identifying the specific causes for negative patient assessment of overall health status can result in successful intervention. The objective of this study is to determine the factors that affect quality of life in both transfused and non-transfused thalassemia patients. Methods: The Dartmouth Care Cooperative Chart System (COOP) questionnaire is a standardized, validated, visual screening tool that screens the major domains affecting quality of life. Patients rate quality of life from excellent (1) to poor (5). Scores of 1 and 2 are normal. A Score of 3 are mild to moderate impairment, and 4 and 5 are severe abnormalities. 50 patients were randomly selected during a comprehensive visit to complete a COOP questionnaire. These results were augmented by a brief medical history and chart review. Results: Forty-eight thalassemia patients, including 25 transfusion dependent (Tx) and 23 non-transfused (Non-Tx) patients (50% female) were randomly selected and completed the COOP questionnaire. The mean age of the total population was 19 years (0.9–37.9 yrs) and was similar in both groups. Half of both groups had scores of 3 or less indicating no severe impairment. However, 56% of patients had ratings of 3 indicating mild to moderate impairment of major domains. Four patients (2 Tx, 2 Non-Tx) had repeated 4–5 ratings in multiple domains indicating severe impairment of quality of life. The most commonly reported affected domains were feelings, such as anxiety, depression, and concern of overall health status or indications of recent deterioration in health. Conclusion: At least 50% of transfusion and non-transfusion dependent thalassemia patients demonstrate some impairment in quality of life. Forty-four percent of the population had a severe impairment in at least one domain. In particular, mental health issues are widespread. In contrast to previous beliefs, non-transfusion dependent patients also suffer serious impairment in quality of life. This data suggests all patients should undergo quality of life assessments and intervention, which focuses on affected domains. Studies to determine if quality of life affects patients’ adherence to chelation therapy are needed.

scholarly journals Análisis de la situación de salud en Cerro Guayabal

2017 ◽  
Vol 1 (1) ◽  
pp. 29
Author(s):  
Yira Annabell Vásquez Giler ◽  
Alina González Hernández ◽  
Paula Salomé Macías Moreira ◽  
Olimpia Victoria Carrillo Farnés
Keyword(s):  
Quality Of Life ◽  
Teaching Practice ◽  
Life Quality ◽  
Disease Process ◽  
Health State ◽  
Cross Sectional ◽  
Calidad De Vida ◽  
Critical Issues ◽  
Quality Health

El Análisis de Situación de Salud es una herramienta que busca mejorar la salud y calidad de vida de poblaciones. Se diseñó una investigación transversal, descriptiva; con doble propósito: relacio- nar condiciones de vida y comportamiento del proceso salud y enfermedad en la comunidad Cerro de Guayabal y realizar ejercicio práctico-docente con estudiantes del quinto semestre de Medicina. Se encuestaron 266 familias, 1134 personas (91%) de la población total. El 71% solo alcanza nivel de formación primaria. Más de la mitad tiene viviendas en condiciones regulares y cultura sanita- ria entre regular y mal. El 87% no tiene necesidades básicas cubiertas. Más del 50% son familias disfuncionales. El 56% se dispensarizó de riesgo y 11% enfermos. Dada las condiciones de vida y ausencia de centro de salud parece existir morbilidad oculta. Existe riesgo de accidentes de tránsito y laboral. Resultó un tema crítico la recolección de residuos, el acceso a agua potable y la conta- minación ambiental. Existe imperiosa necesidad de intervenciones de salud para mejorar el estado de salud y calidad de vida de esta comunidad. Palabras clave: calidad de vida, estado de salud, salud pública. Abstract: The Health Situation Analysis is a tool that seeks to improve the health and quality of life of pop- ulations. A cross-sectional descriptive study was designed; with dual purpose: to relate living con- ditions and health behavior and disease process in the Cerro de Guayabal community and make practical-teaching practice with students of the fifth semester of Medicine. 266 families, 1134 people (91%) of the total population were surveyed. Only 71% reached primary level. More than half are in regular housing conditions and health culture fair to poor. 87% do not cover basic needs. More than 50% are dysfunctional families. 56% were risk dispensary and 11% were sick. Given the living conditions and lack of health center it seems to be hidden morbidity. There is a risk of traffic and labor accidents. Waste collection, access to drinking water and environmental pollution were critical issues. There is an urgent need for health interventions to improve the health state and quality of life of this community. Key words: life quality, health state, public health.

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