scholarly journals Affective disturbances in individuals with methylphenidate use disorder at abstinence

2021 ◽  
Author(s):  
Jie Xu ◽  
Yi Zhang ◽  
Pei Sun ◽  
Ti-Fei Yuan
Keyword(s):  
Management Strategies ◽  
Rehabilitation Program ◽  
Depression Symptoms ◽  
Drug Rehabilitation ◽  
Affective States ◽  
Hyperactivity Disorder ◽  
Trade Name ◽  
Nonmedical Use ◽  
Affective Disturbances ◽  
Abstinence Period

Abstract Background Methylphenidate, mainly sold under the trade name Ritalin, is used to clinically treat attention-deficit/hyperactivity disorder (ADHD). There has been an increase in the prevalence of the nonmedical use of methylphenidate among adolescents in the past 30 years. Methods Here, we retrospectively analyzed a clinical dataset of 61 individuals with methylphenidate use disorder who were admitted to a drug rehabilitation program at Beijing Gaoxin Hospital from January 2017 to March 2019. Results The results showed that the majority of individuals with methylphenidate use disorder were adolescents, and the onset of drug use was mainly driven by academic purposes. The abstinence period was accompanied by severe anxiety and depression symptoms in these subjects, and these symptoms were significantly alleviated following four weeks of treatment. In addition, high levels of social support is associated with better affective states. Conclusion To sum up, methylphenidate use disorder individuals are associated with mood disturbances at abstinence, which might be implicated in clinical management strategies.

Twitter Analysis of the Nonmedical Use and Side Effects of Methylphenidate, and User Sentiment about the Drug (Preprint)

2019 ◽  
Author(s):  
Jungu Kim ◽  
Su Cheol Kim ◽  
Jaegwon Jeong ◽  
Myeong Gyu Kim
Keyword(s):  
Side Effects ◽  
Social Networking ◽  
Brand Names ◽  
Social Networking Services ◽  
Hyperactivity Disorder ◽  
Search Terms ◽  
Nonmedical Use ◽  
Twitter Analysis ◽  
Sentiment Score ◽  
The Cost

BACKGROUND Methylphenidate, a stimulant used to treat attention deficit hyperactivity disorder (ADHD), has the potential for nonmedical uses such as study and recreation. In the era of active use of social networking services (SNSs), experience with the nonmedical use or side effects of methylphenidate might be shared on Twitter. OBJECTIVE To analyze monthly tweets about methylphenidate, its nonmedical use and side effects, and user sentiments about methylphenidate. METHODS Tweets mentioning methylphenidate from August 2018 to July 2019 were collected using search terms for methylphenidate and its brand names. Only tweets written in English were included. The monthly number of tweets about methylphenidate and the number of tweets containing keywords related to the nonmedical use and side effects of methylphenidate were analyzed. Precision was calculated as the number of true nonmedical use or side effects divided by the number of tweets containing each keywords. Sentiment analysis was conducted using the text and emoji in tweets, and tweets were categorized as very negative (less than -3), negative (-3 to -1), neutral (0), positive (1 to 3), or very positive (more than 3), depending on the sentiment score. RESULTS A total of 4,169 tweets were ultimately selected for analysis. The number of tweets per month was lowest in August (n=264) and highest in May (n=435). There were 292 (7.0%) tweets about nonmedical uses of methylphenidate. Among those, 200 (4.8%) described use for studying, and 15 (0.4%) described use for recreation. In 91 (2.2%) tweets, snorting methylphenidate was mentioned. Side effects of methylphenidate, mainly poor appetite (n=74, 1.8%) and insomnia (n=54, 1.3%), were reported in 316 (7.6%) tweets. The average sentiment score was 0.027 ± 1.475, and neutral tweets were the most abundant (n=1,593, 38.2%). CONCLUSIONS Tweets about methylphenidate were most abundant in May, mentioned nonmedical use for study or recreation, and contained information about side effects. Analysis of Twitter has the advantage of saving the cost and time needed to conduct a survey, and could help identify nonmedical uses and side effects of drugs.

Integrating Hepatitis, STD, and HIV Services into a Drug Rehabilitation Program

2005 ◽  
Vol 29 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Robert A. Gunn ◽  
Marjorie A. Lee ◽  
David B. Callahan ◽  
Patricia Gonzales ◽  
Paula J. Murray ◽  
...  
Keyword(s):  
Rehabilitation Program ◽  
Drug Rehabilitation ◽  
Hiv Services

scholarly journals Recurrent Thrombotic Vasculopathy in a Former Cocaine User

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Preeti Jadhav ◽  
Hassan Tariq ◽  
Masooma Niazi ◽  
Giovanni Franchin
Keyword(s):  
Clinical Presentation ◽  
Rehabilitation Program ◽  
The Body ◽  
Drug Rehabilitation ◽  
Cocaine User ◽  
Cocaine Use ◽  
The Past ◽  
Urine Toxicology ◽  
History Of ◽  
Infectious Etiology

We report a case of a 35-year-old female who presented to the emergency room (ER) complaining of a pruritic rash involving multiple areas of the body. She had a significant history of cocaine use in the past. She had first developed a similar rash in 2013 when she was diagnosed with cocaine-induced vasculitis. Her urine toxicology had been positive for cocaine in the past until July 2013. She was incarcerated and attended a drug rehabilitation program after which she quit cocaine use, which was consistent with negative urine toxicology on subsequent admissions. Further workup did not reveal any other, autoimmune or infectious, etiology of this clinical presentation. The patient underwent biopsy of the skin lesion that was consistent with thrombotic vasculopathy likely secondary to levamisole.

scholarly journals Effectiveness of e-Health cardiac rehabilitation program on quality of life associated with symptoms of anxiety and depression in moderate-risk patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Raquel Bravo-Escobar ◽  
Alicia González-Represas ◽  
Adela María Gómez-González ◽  
Ángela Heredia-Torres
Keyword(s):  
Quality Of Life ◽  
Cardiac Rehabilitation ◽  
Rehabilitation Program ◽  
Anxiety And Depression ◽  
Depression Symptoms ◽  
Cardiac Rehabilitation Program ◽  
Moderate Risk ◽  
Risk Patients ◽  
The Impact

AbstractExploring new models of medical care requires evaluating the impact of new care strategies not only on physiological parameters but also on the quality of life of the patient. On the other hand the presence of anxiety together with depression requires further consideration when planning appropriate management strategies. The aim of this study was to examine the effectiveness of a home-based cardiac rehabilitation program incorporating an e-Health technology on health-related quality of life associated with symptoms of anxiety and depression in moderate-risk patients. A multicenter, randomized controlled clinical trial was designed to compare a traditional hospital based cardiac rehabilitation program (n = 38, 35 male) with a mixed home surveillance program where patients exercised at home with a remote electrocardiographic monitoring device (n = 33, 31 male). The Short Form-36 (SF-36) Health Survey and the Goldberg questionnaire were used to evaluate quality of life and the presence of symptoms of anxiety and depression respectively. The results of this study show that the type of cardiac rehabilitation program did not influence the improvement in quality of life (p = 0.854), but the presence of symptoms of anxiety and depression did (p = 0.001). Although both programs achieved a decrease in anxiety and depression symptoms and improved functional capacity (p ≤ 0.001), a significant interaction effect was found between the group with or without anxiety and depression symptoms and the type of program in the bodily pain dimension (p = 0.021). Trial registration: Retrospectively registered NCT02796404 (10/06/2016) in clinialtrials.gov.

Marijuana: A Crude Drug with a Spectrum of Underappreciated Toxicity

PEDIATRICS ◽  
1984 ◽  
Vol 73 (4) ◽  
pp. 455-458 ◽  
Author(s):  
Richard H. Schwartz
Keyword(s):  
Cannabis Sativa ◽  
General Term ◽  
Rehabilitation Program ◽  
Central American ◽  
Drug Rehabilitation ◽  
Good Person ◽  
School Work ◽  
Crude Drug ◽  
Self Image ◽  
Vocational Goals

The unthinkable happened to our family. Our son Keith, aged 15 years, experimented with marijuana and quickly became obsessed with getting "high." Keith soon sought out only those friends of a similar ilk and within a few months we began to notice progressive fatigue, disinterest in family life and school work (grades plummeted), loss of academic and vocational goals, a couldn't-care-less attitude, and compulsive dishonesty. Keith had always been a difficult child but we were hopeful that time and love would help him outgrow his poor self-image and impulsive behaviors. Perhaps, without marijuana, we might have seen him mature and become a motivated selfsufficient citizen without the need for intensive drug rehabilitation. For the past 8 months, Keith has been a client at a unique drug rehabilitation program, Straight, Inc, where he is learning that he is a worthwhile, basically good person; that his family loves and needs him; and that he will have a life-long fight against the seductive malignant influence of alcohol, marijuana, and other drugs. He is making progress. We take one day at a time. The word marijuana derives from the indigenous Mexican or Central-American word maraguango, a general term meaning any intoxicating substance.1 Marijuana, the dried particles of leaves, small stems, flowers, and achenes (seeds), is a crude drug which owes its psychoactive properties primarily to Δ9-THC, a mixture of nine psychoactive isomers produced by resin-secreting glands of the medicinal varieties of the hemp plant (Cannabis sativa).2 These glands are particularly abundant in the upper leaves and flowering tops of plants of both sexes but are highest in the pistillate (female) plants.

scholarly journals Chromosome 15 Duplication and Attention-Deficit Hyperactivity Disorder

2017 ◽  
Vol 08 (04) ◽  
pp. 660-661
Author(s):  
Sundar Gnanavel
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Case Report ◽  
Attention Deficit ◽  
Management Strategies ◽  
Behavioral Phenotype ◽  
Chromosome 15 ◽  
Diagnosis And Management ◽  
Psychiatric Illnesses ◽  
Hyperactivity Disorder

ABSTRACTChromosome 15 duplication has been associated with a number of psychiatric illnesses including psychosis and autism. However, literature on association with attention-deficit hyperactivity disorder (ADHD) is scant. This case report describes a patient with chromosome 15 duplication diagnosed with ADHD in our neurodevelopmental clinic. The possible biological underpinnings are discussed along with possible challenges in diagnosis and management. The need for better understanding ADHD as a behavioral phenotype in such cases along with need for tailored management strategies is emphasized.

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