Common Microcirculatory Framework for Monitoring Integrated Microcirculation

2021 ◽  
Author(s):  
Yuan Li ◽  
Bing Wang ◽  
Bingwei Li ◽  
Xiaoyan Zhang ◽  
Xueting Liu ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Computer Algorithm ◽  
Z Score ◽  
Dimensionless Form ◽  
Data Set ◽  
The Common ◽  
Identity Property ◽  
Microcirculatory Function ◽  
Integration Efficiency

Abstract Wide variation in magnitudes, units, and ranges of the microcirculatory variables brings hindrance in describing and evaluating the integrated microcirculatory function of tissues. We designed to establish common microcirculatory framework that contains microhemodynamic and microcirculatory oxygen parameters. To integrate microcirculatory information, demo microcirculatory permutations were generated by a computer algorithm based on microcirculatory characteristics. Four dimensionless methods (Z-score, Min-max, L2, and median scaling) were applied to transform microcirculatory data set into the dimensionless form. Three-dimensional (3-D) common microcirculatory framework was constructed and visualized by using Python and Apache ECharts. The performance of the four dimensionless methods in the pre-processing of multiple microcirculatory variables and the establishment of the common microcirculatory framework were compared. Microhemodynamic and microcirculatory oxygen parameters were embedded in the common microcirculatory framework. After processing by Min-max normalization, the transformed multiple microcirculatory values remained positive with fixed range mapping within [0, 1] and maintained the identity property of microcirculation both of microhemodynamic and microcirculatory oxygen variables in the common microcirculatory framework. Conclusively, Min-max normalization displays preferable integration efficiency, compatibility, and adaptability in the establishment of the 3-D visualized multiparametric common microcirculatory framework.

scholarly journals Zonal-mean data set of global atmospheric reanalyses on pressure levels

2018 ◽  
Vol 10 (4) ◽  
pp. 1925-1941 ◽  
Author(s):  
Patrick Martineau ◽  
Jonathon S. Wright ◽  
Nuanliang Zhu ◽  
Masatomo Fujiwara
Keyword(s):  
Three Dimensional ◽  
Reanalysis Data ◽  
Environmental Data ◽  
Data Sets ◽  
Heating Rates ◽  
Data Set ◽  
Intercomparison Project ◽  
Complete Set ◽  
The Common ◽  
Transformed Eulerian Mean

Abstract. This data set, which is prepared for the Stratosphere–troposphere Processes And their Role in Climate (SPARC) Reanalysis Intercomparison Project (S-RIP), provides several zonal-mean diagnostics computed from reanalysis data on pressure levels. Diagnostics are currently provided for a variety of reanalyses, including ERA-40, ERA-Interim, ERA-20C, NCEP–NCAR, NCEP–DOE, CFSR, 20CR v2 and v2c, JRA-25, JRA-55, JRA-55C, JRA-55AMIP, MERRA, and MERRA-2. The data set will be expanded to include additional reanalyses as they become available. Basic dynamical variables (such as temperature, geopotential height, and three-dimensional winds) are provided in addition to a complete set of terms from the Eulerian-mean and transformed-Eulerian-mean momentum equations. Total diabatic heating and its long-wave and shortwave components are included as availability permits, along with heating rates diagnosed from the basic dynamical variables using the zonal-mean thermodynamic equation. Two versions of the data set are provided, one that uses horizontal and vertical grids provided by the various reanalysis centers and another that uses a common grid (CG) to facilitate comparison among data sets. For the common grid, all diagnostics are interpolated horizontally onto a regular 2.5∘×2.5∘ grid for a subset of pressure levels that are common among all included reanalyses. The dynamical (Martineau, 2017, https://doi.org/10.5285/b241a7f536a244749662360bd7839312) and diabatic (Wright, 2017, https://doi.org/10.5285/70146c789eda4296a3c3ab6706931d56) variables are archived and maintained by the Centre for Environmental Data Analysis (CEDA).

Three-dimensional image analysis and visualization in confocal light microscopy

1993 ◽  
Vol 51 ◽  
pp. 158-159
Author(s):  
J. K. Samarabandu ◽  
R. Acharya ◽  
D. R. Pareddy ◽  
P. C. Cheng
Keyword(s):  
Depth Perception ◽  
Computer Graphic ◽  
Three Dimensional ◽  
Cellular Organization ◽  
Data Set ◽  
Computational Burden ◽  
Interactive Operation ◽  
Cell Organization ◽  
Confocal Images ◽  
3D Digitization

In the study of cell organization in a maize meristem, direct viewing of confocal optical sections in 3D (by means of 3D projection of the volumetric data set, Figure 1) becomes very difficult and confusing because of the large number of nucleus involved. Numerical description of the cellular organization (e.g. position, size and orientation of each structure) and computer graphic presentation are some of the solutions to effectively study the structure of such a complex system. An attempt at data-reduction by means of manually contouring cell nucleus in 3D was reported (Summers et al., 1990). Apart from being labour intensive, this 3D digitization technique suffers from the inaccuracies of manual 3D tracing related to the depth perception of the operator. However, it does demonstrate that reducing stack of confocal images to a 3D graphic representation helps to visualize and analyze complex tissues (Figure 2). This procedure also significantly reduce computational burden in an interactive operation.

EMCAT: An automatic image-processing system for electron-microscopic tomography

1994 ◽  
Vol 52 ◽  
pp. 418-419
Author(s):  
Weiping Liu ◽  
John W. Sedat ◽  
David A. Agard
Keyword(s):  
Image Processing ◽  
Structural Information ◽  
Imaging Technique ◽  
Three Dimensional ◽  
Processing System ◽  
Electron Microscopic ◽  
Data Set ◽  
Ordered Structures ◽  
Automatic Image Processing ◽  
Em Tomography

Any real world object is three-dimensional. The principle of tomography, which reconstructs the 3-D structure of an object from its 2-D projections of different view angles has found application in many disciplines. Electron Microscopic (EM) tomography on non-ordered structures (e.g., subcellular structures in biology and non-crystalline structures in material science) has been exercised sporadically in the last twenty years or so. As vital as is the 3-D structural information and with no existing alternative 3-D imaging technique to compete in its high resolution range, the technique to date remains the kingdom of a brave few. Its tedious tasks have been preventing it from being a routine tool. One keyword in promoting its popularity is automation: The data collection has been automated in our lab, which can routinely yield a data set of over 100 projections in the matter of a few hours. Now the image processing part is also automated. Such automations finish the job easier, faster and better.

A driver drowsiness and distraction warning system based on raspberry Pi 3 Kit

2019 ◽  
Vol 70 (3) ◽  
pp. 184-192
Author(s):  
Toan Dao Thanh ◽  
Vo Thien Linh
Keyword(s):  
Processing System ◽  
Warning System ◽  
Raspberry Pi ◽  
Data Set ◽  
Lower Lip ◽  
Driver Drowsiness ◽  
Image Sensing ◽  
The Face ◽  
The Common ◽  
University Laboratory

In this article, a system to detect driver drowsiness and distraction based on image sensing technique is created. With a camera used to observe the face of driver, the image processing system embedded in the Raspberry Pi 3 Kit will generate a warning sound when the driver shows drowsiness based on the eye-closed state or a yawn. To detect the closed eye state, we use the ratio of the distance between the eyelids and the ratio of the distance between the upper lip and the lower lip when yawning. A trained data set to extract 68 facial features and “frontal face detectors” in Dlib are utilized to determine the eyes and mouth positions needed to carry out identification. Experimental data from the tests of the system on Vietnamese volunteers in our University laboratory show that the system can detect at realtime the common driver states of “Normal”, “Close eyes”, “Yawn” or “Distraction”

Applying Possessive pronoun in Writing Sentences: Exploring Students’ Ability and Problems in a Mixed Method Study

2019 ◽  
Vol 1 (3) ◽  
pp. 79-83
Author(s):  
Eka Utami Putri ◽  
Syahdan Syahdan
Keyword(s):  
Mixed Method ◽  
Simple Random Sampling ◽  
Average Score ◽  
Mixed Method Study ◽  
Z Score ◽  
Possessive Pronoun ◽  
Efl Students ◽  
The Common ◽  
Common Problems ◽  
Essay Test

The purpose of this research was to find out the students' ability in applying Possessive pronoun in writing sentences and the problems encounter it.  This mixed method study employs an explanatory design to reveals it. 53 students out of 105 students from1st semester EFL students from one reputable University in Pekanbaru, Indonesia, were invited to this study. These 53 students were selected using simple random sampling and enrolled for an essay test and interview to see the students' ability and explaining the problems. The data analysis using SPSS showed that the average score of students was 52.98. Meanwhile for the median is 48, the mode is 20. The score of Standard Deviation is 27.93, Variance is 780.25, and Range is 84.  Z-Score was found 41.5%, which is means higher than average and 58.5% while, students' ability was indicated below the average. It showed that the students were low ability in applying possessive pronoun in writing sentences. The study also found the common problems, i.e., (1) students still mixed up between possessive pronoun and possessive adjectives. (2) students used the wrong pattern in using a possessive pronoun. (3) students did not understand clearly about a possessive pronoun, (4) experiencing difficulties in learning possessive pronoun. 

Synthetic Strategies to Access Heteroatomic Spirocentres Embedded in Natural Products

Synthesis ◽  
2021 ◽  
Author(s):  
Michael P. Badart ◽  
Bill C. Hawkins
Keyword(s):  
Natural Products ◽  
Heterocyclic Compound ◽  
Chemical Space ◽  
Three Dimensional ◽  
Coupling Reactions ◽  
Conjugate Additions ◽  
Biological Targets ◽  
Compound Libraries ◽  
The Common ◽  
Significant Attention

AbstractThe spirocyclic motif is abundant in natural products and provides an ideal three-dimensional template to interact with biological targets. With significant attention historically expended on the synthesis of flat-heterocyclic compound libraries, methods to access the less-explored three-dimensional medicinal-chemical space will continue to increase in demand. Herein, we highlight by reaction class the common strategies used to construct the spirocyclic centres embedded in a series of well-studied natural products.1 Introduction2 Cycloadditions3 Palladium-Catalysed Coupling Reactions4 Conjugate Additions5 Imines, Aminals, and Hemiaminal Ethers6 Mannich-Type Reactions7 Oxidative Dearomatisation8 Alkylation9 Organometallic Additions10 Conclusions

Preoperative Use of CT Angiography in Infants With Coarctation of the Aorta

2017 ◽  
Vol 8 (2) ◽  
pp. 196-202 ◽  
Author(s):  
Kirsten Rose-Felker ◽  
Joshua D. Robinson ◽  
Carl L. Backer ◽  
Cynthia K. Rigsby ◽  
Osama M. Eltayeb ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Surgical Approach ◽  
New Technology ◽  
Three Dimensional ◽  
Coarctation Of The Aorta ◽  
Computed Tomographic Angiography ◽  
Great Vessel ◽  
Z Score ◽  
Computed Tomographic ◽  
Tomographic Angiography

Background: Computed tomographic angiography (CTA) and echocardiography (echo) are used preoperatively in coarctation of the aorta to define arch hypoplasia and great vessel branching. We sought to determine differences in quantitative measurements, as well as surgical utility, between modalities. Methods: Infants (less than six months) with both CTA and echo prior to coarctation repair from 2004 to 2013 were included. Measurements were compared and correlated with surgical approach. Three surgeons reviewed de-identified images to predict approach and characterize utility. Computed tomographic angiography radiation dose was calculated. Results: Thirty-three patients were included. No differences existed in arch measurements between echo and CTA ( z-score: −2.59 vs −2.43; P = .47). No differences between modalities were seen for thoracotomy ( z-score: −2.48 [echo] vs −2.31 [CTA]; P = .48) or sternotomy ( z-score: −3.13 [echo] vs −3.08 [CTA]; P = .84). Computed tomographic angiography delineated great vessel branching pattern in two patients with equivocal echo findings ( P = .60). Surgeons rated CTA as far more useful than echo in understanding arch hypoplasia and great vessel branching in cases where CTA was done to resolve anatomical questions that remain after echo evaluation. Two of three surgeons were more likely to choose the surgical approach taken based on CTA (surgeon A, P = .02; surgeon B, P = .01). Radiation dose averaged 2.5 (1.6) mSv and trended down from 2.9 mSv (1.8 mSv; n = 20) to 1.6 mSv (0.5 mSv; n = 7) ( P = .06) with new technology. Conclusion: Although CTA and echo measurements of the aorta do not differ, CTA better delineates branching and surgeons strongly prefer it for three-dimensional arch anatomy. We recommend CTA for patients with anomalous arch branching patterns, diffuse or complex hypoplasia, or unusual arch morphology not fully elucidated by echo.

Harmonic Analysis on Low Quality Tidal Data

2014 ◽  
Author(s):  
Joost den Haan
Keyword(s):  
Harmonic Analysis ◽  
Three Dimensional ◽  
Measurement Data ◽  
Tidal Energy ◽  
Energy Yield ◽  
Profile Measurement ◽  
Current Profile ◽  
Tidal Power ◽  
Data Set ◽  
Tidal Forcing

The aim of the study is to devise a method to conservatively predict a tidal power generation based on relatively short current profile measurement data sets. Harmonic analysis on a low quality tidal current profile measurement data set only allowed for the reliable estimation of a limited number of constituents leading to a poor prediction of tidal energy yield. Two novel, but very different approaches were taken: firstly a quasi response function is formulated which combines the currents profiles into a single current. Secondly, a three dimensional vectorial tidal forcing model was developed aiming to support the harmonic analysis with upfront knowledge of the actual constituents. The response based approach allowed for a reasonable prediction. The vectorial tidal forcing model proved to be a viable start for a full featuring numerical model; even in its initial simplified form it could provide more insight than the conventional tidal potential models.

scholarly journals Crystal structure of a new monoclinic polymorph ofN-(4-methylphenyl)-3-nitropyridin-2-amine

2014 ◽  
Vol 70 (8) ◽  
pp. 58-61
Author(s):  
Aina Mardia Akhmad Aznan ◽  
Zanariah Abdullah ◽  
Vannajan Sanghiran Lee ◽  
Edward R. T. Tiekink
Keyword(s):  
Three Dimensional ◽  
Basis Set ◽  
Dihedral Angles ◽  
Asymmetric Unit ◽  
Acta Cryst ◽  
Common Features ◽  
Compound C ◽  
B3lyp Level ◽  
The Common ◽  
Independent Molecules

The title compound, C12H11N3O2, is a second monoclinic polymorph (P21, withZ′ = 4) of the previously reported monoclinic (P21/c, withZ′ = 2) form [Akhmad Aznanet al.(2010).Acta Cryst.E66, o2400]. Four independent molecules comprise the asymmetric unit, which have the common features of asyndisposition of the pyridine N atom and the toluene ring, and an intramolecular amine–nitro N—H...O hydrogen bond. The differences between molecules relate to the dihedral angles between the rings which range from 2.92 (19) to 26.24 (19)°. The geometry-optimized structure [B3LYP level of theory and 6–311 g+(d,p) basis set] has the same features except that the entire molecule is planar. In the crystal, the three-dimensional architecture is consolidated by a combination of C—H...O, C—H...π, nitro-N—O...π and π–π interactions [inter-centroid distances = 3.649 (2)–3.916 (2) Å].

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