Risk Factors and Causes of Fever after Endoscopic Submucosal Dissection

Author(s):  
Ming Chen ◽  
Jinqi Liu ◽  
Xiaoxue Zhang ◽  
Dongyang Wang ◽  
Haipeng Wang ◽  
...  

Abstract Background To investigate the fever and related risk factors of gastrointestinal mucosa or submucosal lesions after endoscopic mucosal dissection(ESD).Method A retrospective analysis of patients undergoing ESD. Patients were divided into two groups according to the presence or absence of post-ESD fever. Patient-related factors and lesion-related factors were counted in both groups.Results The incidence of fever was 31.0% in 290 patients after the operation, 87 patients developed fever within 24 hours after operation. The average of (2.82 ± 1.186) days. According to logistic analysis, the surgical site was in the esophagus (OR value: 6.439; 95% CI: 2.030-20.424; P value: 0.002), with diabetes history (OR value: 3.289; 95% CI: 1.015-10.662; P value: 0.047), age≥70.6 years (OR value: 0.844; 95% CI: 0.805-0.884; P value: 0.000), resection diameter> 4.25 mm (OR value: 2.361; 95% CI: 5.202-29.371; P value: 0.000), operation time> 196min (OR value: 1.022; 95% CI: 1.003-1.042; P value: 0.022) were risk factors for fever.Conclusions Older patient, the operation site in esophagus, diabetes, large tumors and long operation time were more likely to develop post-ESD fever, The possibility of bacteremia after ESD is small, antibiotics do not need to be applied in advance.

2020 ◽  
Author(s):  
Lunyang Hu ◽  
Baoli Wang ◽  
Yong Jiang ◽  
Banghui Zhu ◽  
Chen Wang ◽  
...  

Abstract Background: Until now, transfusion-related acute lung injury (TRALI) has been considered to be the leading cause of blood transfusion-related diseases and death. And there is no clinically effective treatment plan for TRALI. The aim of this study was to systematically summarize the literature on risk factors for TRALI in critical patients. Methods: Electronic searches (up to March 2020) were performed in the Cochrane Library, Web of Knowledge, Embase, and PubMed databases. We included studies reporting on the risk factors of TRALI for critical patients and extracted the risk factors. Finally, third studies met the inclusion criteria. Results: We summarized and analyzed the potential risk factors of TRALI for critical patients in 13 existing studies. The host-related factors were age (odds ratio (OR) [95% confidence interval] = 1.16 [1.08-1.24]), sex (OR = 1.26 [1.16-1.38]), tobacco use status (OR = 3.82 [1.91-7.65]), chronic alcohol abuse (OR = 3.82 [2.97-26.83]), fluid balance (OR = 1.24 [1.08-1.42]), shock before transfusion (OR = 4.41 [2.38-8.20]), and ASA score of the recipients (OR = 2.72 [1.43-5.16]). The transfusion-related factors were the number of transfusions (OR = 1.40 [1.14-1.72]) and fresh frozen plasma (FFP) units (OR = 1.21 [1.01-1.46]). The device-related factor was mechanical ventilation (OR = 4.13 [2.20-7.76]). Conclusions: The risk factors for TRALI in this study included age, sex, tobacco use, chronic alcohol abuse, fluid balance, shock before transfusion, ASA score, number of transfusions, FFP units and mechanical ventilation. Our study suggests that host-related risk factors play a more important role in the occurrence and development of TRALI than blood transfusion-related risk factors.


PEDIATRICS ◽  
1985 ◽  
Vol 75 (5) ◽  
pp. 928-934
Author(s):  
Sarah S. Long

The majority of the almost 400 confirmed cases of infant botulism in the United States have occurred in California, Pennsylvania, and Utah. In Pennsyvania, 44 of 53 (83%) cases occurred within a geographic area of Southeastern Pennsylvania which represents one tenth of the Commonwealth's area and one third of the population at risk for infant botulism. In Southeastern Pennsylvania, a map of the residences of cases circumscribes a discrete ring around Philadelphia. A case-control study performed to seek host-related risk factors, identifies the significant associations of botulism with infants who are white, breast-fed, and born at term into two-parent families with hospitalization insurance. County control studies were performed to identify differences in host-related factors between areas of high and low prevalence of botulism. Although some "protection" could be afforded Philadelphia infants by their feeding and family characteristics, the differences in case rates between Philadelphia and the botulism "ring counties" cannot be explained entirely by host-related factors. Further, the absence of botulism in counties just outside of the botulism "ring," where infants were found to have identical potential risk factors, suggests that an uneven distribution of botulinal spores in the environment is the most significant determinant of case rate.


Author(s):  
Sedigheh Taherpour ◽  
Mojtaba Mousavi Bazzaz ◽  
Hamidreza Naderi ◽  
Saeed Samarghandian ◽  
Alireza Amirabadizadeh ◽  
...  

Introduction: This study aimed to evaluate the incidence of Tuberculosis (TB) among prisoners in Iran, by performing a systematic and meta-analysis study on the related articles. Methodology: Scopus, Iran doc, Cochrane, Pubmed, Medline, Embase and Iran Medex, Magiran, SID, Google Scholar, and EBSCO were searched. After quality assessment of the articles, a fixed or random model, as appropriate, was used to pool the results in a meta-analysis. Heterogeneity between the studies was assessed using I-square and Q-test. Results: The overall sample size of included studies was 19562 that 64 of them were with TB. The highest prevalence of tuberculosis was related to the study of Rasht, 517 in 100,000 but the lowest rate was related to the study of Sought Khorasan, 25 in 100,000. The ES of the random effect model is 0.003 (95% CI, 0.001-0.005) and p-value <0.0001. The Higgins’ I2 of all studies is 86.55%, and the p-value of the Cochrane Q statistics is <0.001, indicating that there is heterogeneity. Based on the Egger regression plot (t=2.18, p = 0.08, CI 95%: -0.001, 0.005) no publication bias existed. Conclusion: The frequency of TB among the prisoners in Iran was low. Due to important limitations in this study, it is not possible to indicate the exact prevalence of TB among prisoners in Iran and compare this with the general population. More studies are needed to assess the related risk factor for designing health interventions plan to decrease the incidence rate of TB among prisoners.


2017 ◽  
Vol 12 (3) ◽  
pp. 200-210 ◽  
Author(s):  
Hannah Arem ◽  
Erikka Loftfield

Approximately 40% of men and women in the United States will be diagnosed with cancer at some point in their lives. There have been dramatic developments in our understanding of cancer development and progression in recent decades, leading to improvements in screening and treatment, and in turn greater numbers of survivors living longer after diagnosis. Epidemiologic evidence of lifestyle-related factors and cancer risk and survival has been explored extensively in the published literature, with recommendations for cancer prevention and control and strategies for implementation evolving over time. This review summarizes the burden of cancer, general measurement issues in cancer epidemiology, and the current state of the science in specific lifestyle-related risk factors and cancer. It is estimated that one third to one half of cancers could be prevented by healthier lifestyle choices.


2019 ◽  
Vol 19 (2) ◽  
pp. 271-277 ◽  
Author(s):  
Pernille L. Petersen ◽  
Pia Bredahl ◽  
Michael Perch ◽  
Christian H. Møller ◽  
Nanna B. Finnerup ◽  
...  

Abstract Background and aims The relative contribution of patient-related factors and intraoperative nerve damage for the development of chronic pain after surgery is unclear. This study aimed to examine chronic pain after bilateral thoracotomy. We hypothesized, that individual patient-related risk factors would be important resulting in an intraindividual uniformity of pain and hyperphenomena between the two sides of the thorax. Methods Twenty patients who had undergone lung transplantation via bilateral thoracotomy 6–12 months previously were included from the Danish Lung Transplant program, Rigshospitalet, Denmark, from October 2016 to August 2017. All patients answered questionnaires about pain in and around the scar, completed the Neuropathic Pain Symptom Inventory, and underwent bedside examination for hyperphenomena (brush- and cold-evoked allodynia, pinprick hyperalgesia) and pinprick hypoalgesia. Results Nine patients reported spontaneous pain bilaterally, five patients had pain on one side only, and six patients had no pain. Hyperphenomena were present on both sides of the thorax in 13 patients, on one side in four patients, and three patients had no hyperphenomena. The intraindividual uniformity of pain (p=0.029) and hyperphenomena (p=0.011) between the two sides of the thorax suggests that patient-related factors play an important role in the development of chronic pain. Conclusions The results of the present study provide support for the hypothesis of an individual predisposition for the development of chronic pain after thoracotomy. Implications Patient-related risk factors contribute to the development of chronic pain after thoracotomy. This result most likely can be transferred to chronic pain after other surgical procedures and therefore help us understand risk factors for chronic pain after surgery.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M Kamenik ◽  
P Widimsky

Abstract Background/Introduction Stent thrombosis (ST) is the most feared complication of percutaneous coronary intervention (PCI). Purpose To analyze the patient-, lesion- and operator-related risk factors of ST. Methods Coronary angiograms of 1764 consecutive patients admitted between 2014–16 with an acute coronary syndrome (ACS) to a large tertiary center have been analyzed retrospectively for the presence of ST. ST was found in 29 of them (1,6% of all ACS patients). Paired angiograms (initial PCI from the time of stent implantation and second angiography done at the time of ST) from these 29 ST patients were analyzed by two independent observers with focus on lesion characteristics and procedure techniques. Clinical and laboratory data were included in the analysis. Results The following risk factors for ST were found: renal insufficiency (OR 4,30; p<0,001), type 2. diabetes (OR 2.24, p=0,03), stent implantation for STEMI (OR 1,75; p=0,009), left main or left anterior descending artery as culprit lesion (OR 2,80; p<0,001), absolute platelet count (p=0,005) and absence of antiplatelet therapy prior to ST (OR 1,87; p=0,01). The rates of lesion-/operator-related factors among ST patients were: bifurcation lesion (n=7; 24%), heavy coronary calcifications (n=13; 44%), wrong stent size selection (diameter undersizing or incomplete lesion coverage) (n=6, 20%). A combination of at least one clinical/laboratory and one lesion/operator risk factor was identified in 28 patients out of 29 with confirmed ST (96%). Conclusion Stent thrombosis usually occurs when clinical, laboratory, lesion and/or operator-related risk factors combine together. While clinical, laboratory and lesion-related factors are well described in the literature, operator-related factors need more detailed research.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyum-Yil Kwon ◽  
Suyeon Park ◽  
Eun Ji Lee ◽  
Mina Lee ◽  
Hyunjin Ju

AbstractThe association of non-motor symptoms (NMSs) with fall-related factors in patients with Parkinson’s disease (PD) remains to be further elucidated in the early stages of the disease. Eighty-six patients with less than 5 years of the onset of PD were retrospectively enrolled in the study. We assessed potential fall-related risk factors including (1) a history of falls during the past year (faller versus non-faller), (2) the fear of falling (FoF), and (3) the freezing of gait (FoG). Different types of NMSs were measured using the Montreal Cognitive Assessment (MoCA), the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), the Parkinson’s disease Fatigue Scale (PFS), and the Scales for Outcomes in Parkinson’s disease—Autonomic dysfunction (SCOPA-AUT). The faller group (37.2%) showed higher scores for BDI, BAI, PFS, and SCOPA-AUT, compared to the non-faller group. From logistic regression analyses, the prior history of falls was related to the gastrointestinal domain of SCOPA-AUT, FoF was associated with BAI, and gastrointestinal and urinary domains of SCOPA-AUT, and FoG was linked to BAI and gastrointestinal domain of SCOPA-AUT. In conclusion, we found that fall-related risk factors in patients with early PD were highly connected with gastrointestinal dysautonomia.


2020 ◽  
Vol 6 (2) ◽  
pp. 77-81
Author(s):  
Mozhgan Taghizadeh ◽  
Mahdi Foroughian ◽  
Hamidreza Vakili ◽  
Seyed Reza Habibzadeh ◽  
Reza Boostani ◽  
...  

Objective: Intracerebral hemorrhage (ICH) following systemic and chronic hypertension is one of the main causes of acute stroke leading to disability and death. Identifying the risk factors in ICH patients can be effective in reducing bleeding and the rates of mortality and disability in these patients. This study was carried out to investigate the factors associated with ICH. Methods: A total of 134 patients with chronic systemic hypertension who had ICH were enrolled in this study. The amount of ICH was measured through computed tomography (CT scan). The subjects were divided into two groups of high (>30 mL) and low (<30 mL) ICH volume, and the related risk factors in the two groups were studied and compared using SPSS software version 21. Results: The mean age of the subjects was 66.04 years, and 71 (52.99%) individuals were females. The mean volume of ICH was 24.47 mL, with 29.10% of the subjects (39 patients) having >30 mL and 70.90% (95 patients) having <30 mL of ICH. The results of studying ICHrelated factors in the multiple logistic regression showed that ischemic heart disease (IHD) (odds ratio [OR] = 2.243, P value <0.05) and cardiovascular disease (OR = 3.294, P value <0.05) were the co-existing diseases that increased the odds of developing ICH. Conclusion: The results of this study showed that less than 30% of the subjects had high volumes of bleeding, and the co-existence of IHD was considered as a strong independent risk factor affecting the volume of ICH associated with worse prognosis.


2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Mingchao Li ◽  
Ping Guo ◽  
Jihua Zeng ◽  
Chi Li ◽  
Qiuming Ji ◽  
...  

Abstract Background There are still few studies on the clinical characteristics and related risk factors of schizophrenia patients with intestinal obstruction. Our aim is to explore the clinical characteristics and related risk factors of schizophrenia patients with intestinal obstruction. Methods This study focused on schizophrenia patients with intestinal obstruction who were hospitalized in the psychiatric department of a hospital in Wuhan from January 2007 to December 2020 as the main research object. We intend to retrospectively analyze the clinical characteristics and related risk factors of schizophrenia patients with intestinal obstruction. Results In the 1937 persons with schizophrenia included in this study, 97 patients were complicated with intestinal obstruction, and the incidence was 5.01%.The results of the study showed that patients with age ≥ 60 years old, visiting time ≥ 24 h, hospital stay ≥ 90 days, history of abdominal surgery, course of disease ≥ 5 years, male, and patients with cardiovascular and cerebrovascular diseases are prone to intestinal obstruction; Logistic multiple regression analysis showed that the related risk factors of schizophrenia patients with intestinal obstruction mainly included the patient's age, visiting time, length of hospital stay, history of abdominal surgery, course of disease and gender. Conclusion The older the age, the longer the hospital stay, the longer the course of the disease, the history of previous surgery, and the male schizophrenia who do not see a doctor within 24 h of the onset, the risk of intestinal obstruction is higher, and it is easy to be misdiagnosed and even life-threatening.


PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254926
Author(s):  
Mst. Sabrina Moonajilin ◽  
Md Khalid Ibne Kamal ◽  
Firoj al Mamun ◽  
Mariam Binte Safiq ◽  
Ismail Hosen ◽  
...  

Substance abuse is a major concern worldwide and is increasing rapidly in Bangladesh. However, there are no prior studies concerning lifestyle-related factors that influence adolescents’ substance use behavior. Therefore, the present study investigated the prevalence of substance use and its associated sociodemographic and lifestyle-related risk factors among a total of 424 Bangladeshi high school-going adolescents through a structured questionnaire interview study. The survey questionnaire consisted of socio-demographics, lifestyle-related information, and substance use-related questions. For data analysis, descriptive and inferential statistics were performed using SPSS (Statistical Package for Social Science) version 22.0, and a p-value of <0.05 determined statistical significance. Results showed that 21.2%, 14.4%, and 15.1% of the participants reported smoking, using a drug, and consuming alcohol, respectively, at least once during their lifespan; whereas the current (i.e., past-month) rates were reported to be 10.4%, 2.8%, and 3.1%, respectively. Overall, the current substance use risk factors were identified as being male, not being from science academic background, having less family influence on personal life, irregular teeth brushing, being smartphone users, using a smartphone for a longer time, and being late-night sleepers. From the list of identified risk factors of substance use, those that are modifiable may be targeted to evolve a prevention program to manage this problem in Bangladeshi adolescents.


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