A Rare Pathogen Comamonas Testosteroni: A Case Report And Review of The Literature

Abstract Comamonas testosteroni is a Gram- negative, aerobic, motile, non-spore-forming bacillus. It has not been recognized as a component of the endogenous human microflora. Due to its ability to survive in liquid environments, it can survive for a long time in a hospital environment and cause opportunistic infections. Although rare, C. testosteroni has been reported as a cause of cellulitis, peritonitis, endocarditis, meningitis, endophthalmitis, tenosynovitis, pneumonia and bacteremia. Here, we present a case of a 4-year-old girl who was operated on for persistent cloaca with C. testosteroni isolated in her urine culture. Identification studies were performed by MALDI-TOF MS (bioMerieux, France) mass spectrophotometer method. Antibiotic susceptibility tests were performed with the automatic device VITEK-2 Compact (bioMérieux, France). Microorganism was found susceptible to ceftazidime and ciprofloxacin; intermediate susceptible to meropenem and piperacillin / tazobactam and resistant to gentamicin, amikacin, imipenem and trimethoprim-sulfamethoxazole. With this case report, C. testosteroni was reported as the first cause of urinary tract infection in our country and the third in the world.

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COVID-19-associated rhino-orbital mucormycosis (CAROM)—a case report

Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1186/s43055-021-00547-5 ◽

2021 ◽

Vol 52 (1) ◽

Author(s):

Humsheer Singh Sethi ◽

Kamal Kumar Sen ◽

Sudhansu Sekhar Mohanty ◽

Sangram Panda ◽

Kolluru Radha Krishna ◽

...

Keyword(s):

Case Report ◽

Health Care Professionals ◽

Opportunistic Infections ◽

Fungal Spores ◽

Nasal Discharge ◽

Contributing Factors ◽

Post Discharge ◽

Pulmonary Mucormycosis ◽

The Right

Abstract Background There has been a rapid rise in the number of COVID-19-associated rhino-orbital mucormycosis (CAROM) cases especially in South Asian countries, to an extent that it has been considered an epidemic among the COVID-19 patients in India. As of May 13, 2021, 101 CAROM cases have been reported, of which 82 cases were from India and 19 from the rest of the world. On the other hand, pulmonary mucormycosis associated with COVID-19 has a much lesser reported incidence of only 7% of the total COVID-19-associated mucormycosis cases (Singh AK, Singh R, Joshi SR, Misra A, Diab Metab Syndr: Clin Res Rev, 2021). This case report attempts to familiarize the health care professionals and radiologists with the imaging findings that should alarm for follow-up and treatment in the lines of CAROM. Case presentation Rhino-orbital mucormycosis (ROM) is a manifestation of mucormycosis that is thought to be acquired by inhalation of fungal spores into the paranasal sinuses. Here, we describe a 55-year-old male, post COVID-19 status with long standing diabetes who received steroids and ventilator therapy for the management of the viral infection. Post discharge from the COVID-19 isolation ICU, the patient complained of grayish discharge from the right nostril and was readmitted to the hospital for the nasal discharge. After thorough radiological and pathological investigation, the patient was diagnosed with CAROM and managed. Conclusion Uncontrolled diabetes and imprudent use of steroids are both contributing factors in the increased number of CAROM cases. Our report emphasizes on the radiological aspect of CAROM and reinforces the importance of follow-up imaging in post COVID-19 infection cases with a strong suspicion of opportunistic infections.

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Widespread pulmonary granulomatosis following long time intravenous drug abuse—A case report

Forensic Science International ◽

10.1016/j.forsciint.2009.12.066 ◽

2010 ◽

Vol 197 (1-3) ◽

pp. e27-e30 ◽

Cited By ~ 21

Author(s):

R.B. Dettmeyer ◽

M.A. Verhoff ◽

B. Brückel ◽

D. Walter

Keyword(s):

Case Report ◽

Drug Abuse ◽

Intravenous Drug ◽

Intravenous Drug Abuse ◽

Long Time

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Prolonged Pneumococcal Meningitis Due to an Organism With Increased Resistance to Penicillin

PEDIATRICS ◽

10.1542/peds.58.3.378 ◽

1976 ◽

Vol 58 (3) ◽

pp. 378-381 ◽

Cited By ~ 1

Author(s):

Abel Paredes ◽

Larry H. Taber ◽

Martha D. Yow ◽

Dorothy Clark ◽

William Nathan

Keyword(s):

Case Report ◽

Streptococcus Pneumoniae ◽

Pneumococcal Meningitis ◽

Pneumococcal Infections ◽

In Vitro Susceptibility ◽

Focus Of Infection ◽

Resistance To Penicillin ◽

Penicillin Treatment ◽

Susceptibility Tests

For more than 30 years, penicillin has been the agent of choice for pneumococcal infections. During this time the majority of strains of Streptococcus pneumoniae have been highly susceptible to penicillin. However, during the last ten years there have been sporadic reports of pneumococci with increased resistance to penicillin. The case report of an 18-month-old white boy with meningitis due to a strain of S. pneumoniae with increased resistance to penicillin is presented. The MIC of the organism to penicillin was 0.2µg/ml and the MBC 0.39µg/ml. The patient had normal immunity and no demonstrable sequestered focus of infection but failed to respond to appropriate doses of intravenous penicillin. Treatment with chloramphenicol caused a dramatic bacteriologic and clinical response. This experience reemphasizes the existence of pneumococcal strains of intermediate penicillin sensitivity and the importance of in vitro susceptibility tests.

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THE FIRST INVESTIGATION OF AAC(6’)-Ib ENZYME IN CARBAPENEM-RESISTANT ENTEROBACTERIACEAE ISOLATED FROM INDONESIAN PATIENTS

Acta Biochimica Indonesiana ◽

10.32889/actabioina.v2i1.32 ◽

2019 ◽

Vol 2 (1) ◽

pp. 8-14

Author(s):

Beauty Novianty ◽

Ella Amalia ◽

Ziske Maritska ◽

Yuwono Yuwono ◽

Lusia Hayati

Keyword(s):

Resistance Mechanism ◽

Test Results ◽

Gram Negative ◽

Therapy Options ◽

The Past ◽

Carbapenem Resistant ◽

Long Time ◽

Pcr Method ◽

Vitek 2 ◽

Carbapenem Resistant Enterobacteriaceae

Background: Over the past decade, numbers of Carbapenemase Producing-Carbapenem Resistant Enterobacteriaceae (CP-CRE) has been increasing worldwide and it has been becoming a threat because of its resistance against carbapenem which is considered as the “last resort” antibiotic. Therapy options for its infection are still limited. Aminoglycoside serves as one of the most commonly used antibiotics, but the resistance against it has already been presented for a long time. Aminoglycoside Modifying Enzyme (AME) is the most important resistance mechanism against aminoglycoside. AAC(6’)-Ib enzyme is one of the most common AME produced by the gram-negative bacteria.Objectives: This study wished to identify the gene of this enzyme among CRE isolated from infected Indonesian patients in Dr. Mohammad Hoesin Hospital Palembang.Methods: Twenty-eight isolates collected from CRE-infected patients identified by Vitek 2 Compact (bioMerieux, USA) in dr. Mohammad Hoesin Hospital Palembang during September—November 2017. AAC(6’)-Ib gene was identified using PCR method, then visualize by electrophoresis. The result is then analyzed by comparing it with a susceptibility test. Results: Out of 28 samples, AAC(6’)-Ib is identified in 22 (78.57%) samples. Samples with AAC(6’)-Ib showed to be less resistant to various antibiotics, significantly to amikacin (p=0.023).Conclusion: AAC(6’)-Ib gene is found in most of samples implying its frequent occurrence in Indonesian patients.

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Case Report on Rheumatoid Arthritis

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i39a32162 ◽

2021 ◽

pp. 212-216

Author(s):

Roshani Dhanvijay ◽

Savita Pohekar

Keyword(s):

Rheumatoid Arthritis ◽

Case Report ◽

Autoimmune Disorder ◽

The Body ◽

Health Care Practitioner ◽

Recurrent Pain ◽

Reactive Protein ◽

Rheumatoid Arthritis Joint ◽

Long Time ◽

Tunnel Syndrome

Rheumatoid arthritis (RA) is an autoimmune disorder that inhibits the body's immune system that induces inflammation in the injured areas of the body. It is commonly caused the joints of the palms, wrists, and knees. An inflaming rheumatoid arthritis joint contributes to joint tissue damage. This condition may cause chronic or long term discomfort, instability, and deformation. Symptoms include exhaustion, pain, and depression. If the patient does not undergo early diagnosis and care for symptoms, a series of symptoms can arise including Osteoporosis, rheumatoid nodules, dry eye and mouth, carpal tunnel syndrome Case Report: The female patient name is Yogita Shinde 65-year-old religion Hindu lived in the kandhali. She was admitted to AVBR Hospital with the chief complaint of pain in her shoulder and hands, joints pain, swelling on both the hands. She started taking ibuprofen 800 mg 3 times per day to relieve discomfort and rigidity. Three months earlier, as she was doing her job, she had pain on her right and left shoulders. She still started to feel very sleepy and short-tempered. Tab ibuprofen was not an effective very long time for pain. One morning, Yogita couldn't lift her arms without the intense pain of her back. She was conscious that it was time for help. She had spoken to her parents, and they advised her to see a physician. The primary healthcare practitioner (PHP), who tested and carried out a variety of blood test. Positive-rheumatoid factors, CCP antibiotics, higher ESR, and C-reactive protein were seen via the blood samples. These findings were communicated to Yogita and the Rheumatologist was directed at her PCP to see her as soon as possible. The primary health care practitioner inquired about the medical records of Yogita parents and grandparents, family conditions, medical and operative records of yogita, and details on their family and working lives. And after that, the physician started the treatment, after which Yogita feels better for some days. After a few weeks she having recurrent pain in her hand and foot, this is intolerable to her. And then she is admitted to AVBR Hospital on date 20th Sept 2020

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An Uncommon Cause Of Bacteremia: Comamonas Testosteroni (A Case Report)

Türk Mikrobiyoloji Cemiyeti Dergisi ◽

10.5222/tmcd.2018.147 ◽

2018 ◽

Author(s):

Gülseren Samancı Aktar ◽

Zeynep Ayaydın ◽

Arzu Rahmanalı Onur ◽

Demet Gür Vural ◽

Hakan Temiz

Keyword(s):

Case Report ◽

Comamonas Testosteroni

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Three different opportunistic infections in the same renal allograft recipient at the same time: Unusual case report

Tropical Journal of Medical Research ◽

10.4103/1119-0388.130185 ◽

2014 ◽

Vol 17 (1) ◽

pp. 45 ◽

Cited By ~ 1

Author(s):

Rohit Rungta ◽

DeepakShankar Ray ◽

Pratik Das ◽

Soumava Gupta

Keyword(s):

Case Report ◽

Unusual Case ◽

Renal Allograft ◽

Opportunistic Infections ◽

Renal Allograft Recipient ◽

Unusual Case Report

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Cefotaxime-Resistant EnterobacteriaceaeIsolates from a Hospital in Warsaw, Poland: Identification of a New CTX-M-3 Cefotaxime-Hydrolyzing β-Lactamase That Is Closely Related to the CTX-M-1/MEN-1 Enzyme

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.42.4.827 ◽

1998 ◽

Vol 42 (4) ◽

pp. 827-832 ◽

Cited By ~ 122

Author(s):

Marek Gniadkowski ◽

Ines Schneider ◽

Andrzej Pal/ucha ◽

Renate Jungwirth ◽

Barbara Mikiewicz ◽

...

Keyword(s):

Amino Acid ◽

Clinical Laboratory ◽

Amino Acid Sequences ◽

Hospital Environment ◽

M Gene ◽

E Coli ◽

Men 1 ◽

Long Time ◽

Dna Restriction ◽

Tract Infections

ABSTRACT A group of cefotaxime-resistant Citrobacter freundiiand Escherichia coli isolates were collected by a clinical laboratory in a hospital in Warsaw, Poland, in July 1996. Detailed analysis has shown that all of these produced a β-lactamase (pI, 8.4) belonging to the CTX-M family, one of the minor extended-spectrum β-lactamase families with a strong cefotaxime-hydrolyzing activity. Sequencing has revealed that C. freundii isolates produced a new CTX-M-3 enzyme which is very closely related to the CTX-M-1/MEN-1 β-lactamase, sporadically identified in Europe over a period of 6 years. Amino acid sequences of these two β-lactamases differ at four positions: Val77Ala, Asp114Asn, Ser140Ala, and Asn288Asp (the first amino acid of each pair refers to CTX-M-1/MEN-1 and second refers to CTX-M-3). The partial sequence of the E. coli CTX-M gene was identical to the corresponding region ofbla CTX-M-3, but a transconjugant of theE. coli isolate expressed higher levels of resistance to β-lactams than did C. freundii transconjugants. These resistance differences correlated with differences in plasmid DNA restriction patterns. Our results suggest that CTX-M genes have been spread among different species of the familyEnterobacteriaceae in the hospital and that the CTX-M-3-expressing C. freundii strain causing routine urinary tract infections has been maintained for a relatively long time in the hospital environment.

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Recurrent Pituicytoma in a Pediatric Patient: A Case Report

Arquivos Brasileiros de Neurocirurgia Brazilian Neurosurgery ◽

10.1055/s-0038-1660465 ◽

2018 ◽

Vol 37 (02) ◽

pp. 119-122

Author(s):

Miguel Maldonado-Morán ◽

Jeisson Ospina ◽

Juan Vega ◽

Claudia Restrepo ◽

Daniela Rico ◽

...

Keyword(s):

Emergency Department ◽

Case Report ◽

Pediatric Patient ◽

Glial Cells ◽

Clinical Presentation ◽

Present Report ◽

Rare Tumor ◽

Radiological Features ◽

Long Time ◽

Visual Disturbances

AbstractPituicytoma is a rare tumor that arises from the glial cells of the neurohypophysis. For a long time, it was believed that pituicytomas only appeared in adults. Currently, at least three cases of this entity occurring in children have been reported in the literature. The aim of the present report is to describe the case of a 5-year-old girl who presented to the emergency department with visual disturbances, and the diagnosis was a recurrent pituicytoma. Therefore, the clinical presentation, the radiological features of the tumor, and the corresponding surgical management are described. Additionally, a brief review of the management of this unusual entity was performed.

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