scholarly journals Body Mass Index Is Related to the Recovery After Intra-articular Injection of Triamcinolone Acetonide for the Treatment of Frozen Shoulder: Case Series Study

2021 ◽  
Author(s):  
Yang-Soo Kim ◽  
Bo-Seoung Kim ◽  
Hyo-Jin Lee
Keyword(s):  
Body Mass Index ◽  
Triamcinolone Acetonide ◽  
Body Mass ◽  
External Rotation ◽  
Frozen Shoulder ◽  
Smoking History ◽  
Outcome Variable ◽  
Symptom Duration ◽  
Forward Flexion ◽  
Case Series Study

Abstract Background: Patients with frozen shoulder tend to respond differently to the intra-articular injection of triamcinolone acetonide. The purpose of the present study was to evaluate the clinical effect of glenohumeral injection with triamcinolone acetonide for frozen shoulder and determine the factors related to extent of range of motion (ROM) recovery.Methods: A cohort of patients who underwent intra-articular glenohumeral injection of triamcinolone acetonide under diagnosis of primary frozen shoulder was reviewed. The primary outcome variable of interest was the range of changes in each aspect of ROM at six weeks after injection. The relationship between improvement and unresponsiveness to intra-articular injection for the treatment of frozen shoulder with various factors were evaluated. The analyzed factors were as follows: age, sex, body mass index (BMI), initial ROM before injection, symptom duration, hand dominance, smoking history, and the existence of underlying disease including diabetes mellitus, hypertension, coronary disase, thyroid disease and hypercholesterolemia.Results: A total of 305 patients were reviewed. There were significant improvements in all aspects of ROM at six weeks after injection. The forward flexion (ρ=-0.346, p<0.001) and external rotation (ρ=-0.204, p=0.040) showed a negative correlation with BMI. Multivariate analysis revealed that BMI is the sole factor related to recovery of forward flexion (p=0.032) and external rotation (p=0.007) at six weeks post-injection. Conclusion: Intra-articular injection of triamcinolone acetonide is an effective method for improving ROM in patients with frozen shoulder. Increased BMI showed adverse effects on ROM recovery.

Short-Term Outcomes Following Removal of Infected Hernia Mesh

2021 ◽  
pp. 000313482110241
Author(s):  
Christine Tung ◽  
Junko Ozao-Choy ◽  
Dennis Y. Kim ◽  
Christian de Virgilio ◽  
Ashkan Moazzez
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Logistic Regression ◽  
Body Mass ◽  
Smoking History ◽  
Multivariate Logistic Regression ◽  
Short Term ◽  
Mesh Removal ◽  
Mesh Placement ◽  
Infected Mesh

There are limited studies regarding outcomes of replacing an infected mesh with another mesh. We reviewed short-term outcomes following infected mesh removal and whether placement of new mesh is associated with worse outcomes. Patients who underwent hernia repair with infected mesh removal were identified from 2005 to 2018 American College of Surgeons-National Surgical Quality Improvement Program database. They were divided into new mesh (Mesh+) or no mesh (Mesh-) groups. Bivariate and multivariate logistic regression analyses were used to compare morbidity between the two groups and to identify associated risk factors. Of 1660 patients, 49.3% received new mesh, with higher morbidity in the Mesh+ (35.9% vs. 30.3%; P = .016), but without higher rates of surgical site infection (SSI) (21.3% vs. 19.7%; P = .465). Mesh+ had higher rates of acute kidney injury (1.3% vs. .4%; P = .028), UTI (3.1% vs. 1.3%, P = .014), ventilator dependence (4.9% vs. 2.4%; P = .006), and longer LOS (8.6 vs. 7 days, P < .001). Multivariate logistic regression showed new mesh placement (OR: 1.41; 95% CI: 1.07-1.85; P = .014), body mass index (OR: 1.02; 95% CI: 1.00-1.03; P = .022), and smoking (OR: 1.43; 95% CI: 1.05-1.95; P = .025) as risk factors independently associated with increased morbidity. New mesh placement at time of infected mesh removal is associated with increased morbidity but not with SSI. Body mass index and smoking history continue to contribute to postoperative morbidity during subsequent operations for complications.

scholarly journals Stronger Association between Nucleus Accumbens Density and Body Mass Index in Low-Income and African American Children

2020 ◽  
Vol 5 (2) ◽  
pp. p107
Author(s):  
Shervin Assari
Keyword(s):  
Body Mass Index ◽  
African American ◽  
Nucleus Accumbens ◽  
Body Mass ◽  
Low Income ◽  
Parental Education ◽  
Predictor Variable ◽  
Outcome Variable ◽  
Ses Differences

Background: The nucleus accumbens’ (NAc) size, function, and density influence individuals’ body mass index (BMI). However, little is known about racial and socioeconomic status (SES) differences in the role of NAc density as a predictor of childhood BMI. Objectives: We used the Adolescent Brain Cognitive Development (ABCD) data to investigate racial and SES differences in the effect of NAc density on childhood BMI. Methods: This cross-sectional study included 9497 children between ages 9 and 10. Mixed-effects regression models were used to analyze the data. The predictor variable was NAc density measured using diffusion MRI (dMRI). The outcome variable was BMI, operationalized as a continuous variable. Covariates included sex, age, ethnicity, family structure, and parental education. Race (White, African American, Asian, and Other/mixed) and household income (< 50k, 50-100 k, and 100+ k) were the moderators. Results: High NAc diffusion tension (density) was predictive of higher BMI, net of covariates. However, the positive association between NAc density and BMI was stronger in African Americans than in White, and in low-income than in high-income children. Conclusions: Our findings suggest that although high NAc has implications for children’s BMI, this effect varies across racial and SES groups. More research should be performed on the role of obesogenic environments in altering the effect of NAc on childhood BMI.

Abstract 103: Determinants of Quality of Life in Permanent Pacemaker Patients: a Cross-Sectional Analysis

2014 ◽  
Vol 7 (suppl_1) ◽  
Author(s):  
Rhanderson N Cardoso ◽  
Daniel Garcia ◽  
Alexandre Benjo ◽  
Francisco Macedo ◽  
Cesar Benjo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Body Mass ◽  
Well Being ◽  
Permanent Pacemaker ◽  
Smoking History ◽  
Categorical Variables ◽  
Cross Sectional ◽  
Sf 36

Background: Permanent pacemakers (PPM) have improved cardiovascular outcomes and quality of life (QoL) in patients with a wide variety of cardiac rhythm disturbances. Nevertheless, misperceptions about the safety of daily activities (SODA) and associated factors can compromise patients’ absolute well-being. We aimed to study factors associated with worst QoL in PPM patients. Methods: PPM patients from a tertiary hospital answered an 18-question questionnaire about their perception on the SODA, which was scored based on misperception rate. Patients also answered SF-36, a validated QoL questionnaire which is scored from 0 to 100 on each of its 8 scales. Baseline characteristics were compared to average on SF-36 scales in a cross-sectional model by t-test for categorical variables and by univariable regression for continuous variables. Statistical analysis was done with Stata software 10.0 (Texas). Results: A total of 75 PPM patients aged 65.3±12 years were included, of which 31 (41%) were males. Most common reason for PPM was 3rd degree atrioventricular block (44%). Body mass index (p=0.019) and misperception rate on SODA (p=0.003) presented a significant negative regression coefficient with SF-36 average. Age, gender, average income, Chagas disease etiology, diabetes, hypertension, ejection fraction, NYHA classification, previous myocardial infarction (MI), smoking history and peripheral vascular disease were not significantly associated with SF-36 QoL results. Conclusions: In a cross-sectional study, body mass index and misperceptions about the safety of daily-life activities were associated with worst quality of life in patients with permanent pacemaker. These results suggest that optimal physician education of patients and their families about the SODA for PPM patients may ultimately improve patients’ well-being.

scholarly journals Perception of Body Image and Dietary Habit Among Adults Aged 20–45 Years at Sunyani Metropolis

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 277-277
Author(s):  
Jacob Setorglo ◽  
Philip Narteh Gorleku ◽  
Kyei Roselyn ◽  
Kingsley Kwadwo Asare Pereko
Keyword(s):  
Body Mass Index ◽  
Body Image ◽  
Body Size ◽  
Body Mass ◽  
Who Classification ◽  
The Body ◽  
World Health ◽  
Outcome Variable ◽  
Sugar Consumption ◽  
Normal Body

Abstract Objectives The study assessed the body size perception of respondents against the WHO body mass index and related the body sizes to fat and sugar consumption among 20–45-year-old adults. Methods The study design was a descriptive cross-sectional survey which involved 200 respondents aged 20–45 years, sampled conveniently. at Sunyani. Data on socio-demographic, fat and sugar consumption, anthropometry (weight in kg, height in cm) were collected. The weight and height data were later converted into body mass index using the World Health Organisation (WHO) classification. Sugar and fat intakes were measured by dietary food based assessment. (Analysis was done using IBM SPSS version 25. Proportions were presented for categorical values. Chi square test of association was used to determine relationship between the independent and the dependent outcome variable. Statistical significant was set at and P &lt; 0.05. Results The mean age of the respondents was 35 years. About 35.0% of respondents were males and the rest 65.0% females. Sugar and fat consumption among the respondents were within the recommended dietary allowances. Although 75% of respondents had normal body mass index (kg/m2) and 21% were obese based on the WHO classification, Majority (43.0%) of them perceived their body weights were normal. About 48.1% perceived they are either obese or had normal body size. There was no statistically significant association between respondents’ perceived body image and socio-demographic characteristics except for marital status (X2 = 8.82, P = 0.044). There was no statistically significant association between body image perception and dietary intake of fat and sugar. Conclusions There is great disparity in the perception of respondents body image compared to the WHO classification and married women and men are more particular about how they look. Dietary components studied do not have any association with body image. Funding Sources None.

Early adulthood body mass index, cumulative smoking, and esophageal adenocarcinoma survival.

2014 ◽  
Vol 32 (3_suppl) ◽  
pp. 10-10
Author(s):  
Anna Spreafico ◽  
Linda E. Coate ◽  
Xiaowei Shen ◽  
Rihong Zhai ◽  
Wei Xu ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Esophageal Adenocarcinoma ◽  
Body Mass ◽  
Early Adulthood ◽  
Locally Advanced ◽  
Disease Stage ◽  
Smoking History ◽  
One Year ◽  
The Individual ◽  
Survival Differences

10 Background: Little is known about the individual and combined effect of early-adulthood obesity and cumulative smoking on the survival of esophageal adenocarcinoma (EAC) patients. Methods: We analyzed two independent cohorts of EAC patients: 235 patients from Toronto, Canada (TO, 2006-2011) and 329 patients from Boston, USA (BO,1999-2004). Associations between early adulthood body mass index (EA-BMI) and smoking with overall survival (OS) were assessed using Cox proportional hazard models, adjusted for stage, treatment, and other relevant covariates. Results: Median age (range) for TO dataset was 64(29-88)yrs; for BO dataset, 64(21-91)yrs. Males comprised 86% of TO and 89% of BO datasets. 90% of TO and 98% of BO patients were Caucasians. The Median (range) for packyears was 34 (0.2-118; TO) and 34 (0.2-212; BO). The Median (range) for EA-BMI was 24(15-44; TO) and 24(15-47; BO). Median BMI 1 yr prior to diagnosis was 25(16-43; TO) and 25(20-49; BO). 92% of TO and 88% of BO patients had ECOG 0 or 1. Disease stage distribution (early/locally-advanced/metastatic) was 11%/64%/25% (TO) and 30%/52%/18% (BO). For TO, the aHR for smoking was 1.03 (95%CI: 1.02-1.04; p=8E-08) per packyear, while for BO, smoking also independently conferred worse OS, with aHR of 1.007 (95%CI: 1.002-1.01; p=0.003) for each packyear increase. The aHRs for being underweight (EA-BMI<18.5), overweight (EA-BMI 25-30), and obese (EA-BMI>30) in early adulthood were 2.19 (95%CI: 1.0-4.6), 1.89 (95%CI:1.2-3.0), and 2.49 (95%CI:1.5-4.2), respectively for the TO dataset (global p=0.003 for EA-BMI). In BO, the corresponding values were 1.30 (95%CI: 0.8-2.2), 1.45 (95%CI: 1.0-2.5), and 2.39 (95%CI:1.5-3.8), respectively (global p=0.002). In contrast, BMI at one year prior to diagnosis had no association with OS in either study. Conclusions: Elevated BMI in early adulthood and heavy cumulative smoking history are independently associated with increased mortality risk in two North American EAC populations. These survival differences may reflect comorbidity differences, biological differences or both, and offer insight into how key modifiable behaviors in prevention can also affect cancer prognoses. AS, LC, DCC and GL contributed equally.

scholarly journals The Influence of Depression, Body Mass Index, and Smoking on Serum Inhibin B Levels in Late Reproductive-Aged Women

2006 ◽  
Vol 91 (4) ◽  
pp. 1496-1500 ◽  
Author(s):  
G. M. Lambert-Messerlian ◽  
B. L. Harlow
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Ovarian Reserve ◽  
Psychosocial Functioning ◽  
Reproductive Function ◽  
Inhibin B ◽  
Smoking History ◽  
Serum Samples ◽  
History Of ◽  
History Of Depression

Context: Women experiencing depression have difficult psychosocial functioning, and recent data suggest an earlier onset of menopause. Understanding the biological mechanism for the impairment of reproductive function associated with depression is important. Objective: The objective of the study was to determine whether a lifetime history of depression is associated with reduced ovarian reserve as reflected in serum levels of the granulosa cell product, inhibin B. Design: Residual serum samples from a subset of patients in the Harvard Study of Cycles and Moods were collected. Setting: Patients were recruited from seven Boston-area communities. Patients: Women with or without a history of major depression, based on structured clinical interviews for Diagnostic and Statistical Manual of Mental Disorders, fourth edition, were enrolled. A subset of patients who had provided an early follicular phase blood specimen at study enrollment and two or more other samples over the first 18-month period of follow-up were included. Intervention: There were no interventions. Main Outcome Measure: Serum inhibin B levels were measured. Results: Serum FSH levels were higher in women with a history of depression, whereas inhibin B levels did not differ between groups. Body mass index and age were significantly and inversely related to serum inhibin B levels. Smoking history was noted, for the first time, to have a significant negative association with inhibin B levels. Conclusions: Smoking has a direct negative effect on ovarian reserve, as suggested by decreased serum inhibin B levels. In contrast, effects of depression on the reproductive axis may occur at the level of the pituitary and/or hypothalamus rather than at the gonadal level, as suggested by increased serum FSH levels.

scholarly journals Antinuclear autoantibodies are more prevalent in COPD in association with low body mass index but not with smoking history

Thorax ◽  
2010 ◽  
Vol 66 (2) ◽  
pp. 101-107 ◽  
Author(s):  
H. P. J. Bonarius ◽  
C. A. Brandsma ◽  
H. A. M. Kerstjens ◽  
J. A. Koerts ◽  
M. Kerkhof ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Smoking History ◽  
Antinuclear Autoantibodies ◽  
Low Body Mass Index

scholarly journals Rare and Common Genetic Variants, Smoking and Higher Body Mass Index Are Associated with Earlier Age of Progression to Geographic Atrophy and Neovascular Advanced Stages of Macular Degeneration in a Prospective Analysis

2020 ◽  
Author(s):  
Johanna Seddon ◽  
Rafael Widjajahakim ◽  
Bernard Rosner
Keyword(s):  
Body Mass Index ◽  
Macular Degeneration ◽  
Body Mass ◽  
Genetic Variants ◽  
Geographic Atrophy ◽  
Smoking History ◽  
Behavioral Factors ◽  
Severity Scale ◽  
Age Related ◽  
The Impact

IMPORTANCE Genes and lifestyle factors influence progression to advanced age-related macular degeneration (AAMD). However, the impact of genetic and behavioral factors on age when this transition occurs has not been evaluated prospectively. OBJECTIVE To determine whether genetic and environmental factors are associated with age of progression to AAMD and to quantify the effect on age. DESIGN, SETTING, AND PARTICIPANTS Longitudinal progression to AAMD was based on the severity scale in the Age-Related Eye Disease Study database. Progression was defined as an eye that transitioned from non-advanced dry AMD without any evidence of geographic atrophy (GA) (levels 1-8) to any GA or evidence of neovascularization (NV) or both (levels ≥9) during 13 years follow up. Genotypes were determined from DNA samples. MAIN OUTCOME AND MEASURES A stepwise selection of genetic variants with the eye as the unit of analysis, using age as the time scale, yielded 11 genetic variants associated with overall progression, adjusting for sex, education, smoking history, BMI, baseline severity scale, and AREDS treatment. Multivariate analysis was also performed to calculate the effect of genetic and behavioral factors on age of progression. RESULTS Among 5421 eyes, 1206 progressed. Genetic variants associated with progression to AAMD were in the complement, immune, inflammatory, lipid, extracellular matrix, DNA repair and protein binding pathways. Three of these variants were significantly associated with earlier age of progression, adjusting for other covariates: CFH R1210C (P=0.019) with 4.7 years earlier age at progression among carriers of this mutation, C3 K155Q (P=0.011) with 2.44 years earlier for carriers, and ARMS2/HTRA1 A69S (P=0.012) with 0.67 years earlier per allele. Subjects who were smokers (P<.001) or had high BMI (P=0.006) also had an earlier age at progression (4.1 years and 1.4 years, respectively). CONCLUSIONS Carriers of rare variants in the complement pathway and a common risk allele in ARMS2/HTRA1 develop advanced AMD at an earlier age, and unhealthy behaviors including smoking and higher body mass index lead to earlier age of progression to AAMD.

scholarly journals Evaluation of stability of deep venous thrombosis of the lower extremities using Doppler ultrasound

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052094209
Author(s):  
Shefang Zhang ◽  
Wen Chu ◽  
Hua Wang ◽  
Yajun Liang ◽  
Yajuan Fan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Body Mass ◽  
Doppler Ultrasound ◽  
Area Under The Curve ◽  
Lower Extremities ◽  
Smoking History ◽  
D Dimer

Objective This study aimed to assess using Doppler ultrasound for analyzing stability of deep venous thrombosis (DVT) of the lower extremities. Methods Patients with DVT of the lower extremities who were treated from August 2017 to December 2019 were selected. The patients were divided into stable and unstable groups according to whether thrombus was collected in a filter. Related ultrasound and blood test results were analyzed and compared. Results A total of 126 patients with DVT of the lower extremities were included, of whom 74 were in the stable group and 52 were in the unstable group. There were significant differences in the prothrombin time (PT), and lipoprotein alpha, D-dimer, and triglyceride levels between the groups. D-dimer levels >2800 ug/L, smoking, history of venous thrombosis, PT >13.15 s, and body mass index >24.45 kg/m2 were independent risk factors for stability of DVT of the lower extremities. The area under the curve with combined detection of DVT was significantly higher than that for body mass index, PT, and D-dimer alone. Conclusion Doppler ultrasound may be reliable for analyzing the stability of DVT of the lower extremities. Related strategies targeting risk factors are required for reducing DVT of the lower extremities.

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