Occupational lifting and risk of hypertension, stratified by use of anti-hypertensives, physical activity and age - a prospective cohort study

2020 ◽  
Author(s):  
Mette Korshøj ◽  
Harald Hannerz ◽  
Ruth Frikke-Schmidt ◽  
Jacob Louis Marott ◽  
Peter Schnohr ◽  
...  

Abstract Background Prevalence of hypertension varies across occupations, maybe due to differences in exposure to occupational lifting. This study investigated associations between occupational lifting and hypertension, stratified by use of anti-hypertensives, leisure time physical activity (LTPA), occupational physical activity (OPA) and age.Methods Data from the Copenhagen General Population Study were included. The Copenhagen General Population Study was approved by the local ethical committee (H-KF-01-144/01), and all participation were conducted in accordance with the declaration of Helsinki. Multivariable logistic regression models, adjusted for sex, age, BMI, smoking, school education, mental stress and baseline blood pressure (BP), were applied to estimate: the (i) cross-sectional association (n=67,363) between occupational lifting and hypertension (using anti-hypertensives or BP ≥140/≥90 mmHg), (ii) prospective association (n=7,020) between occupational lifting and risk of an above median change in systolic BP (baseline to follow-up) and/or a shift from no use to use of anti-hypertensives, among the included population and stratified by use of anti-hypertensives, LTPA, OPA and age.Results Cross-sectionally, heavy occupational lifting lowered hypertension risk. Mean baseline BP, showed that the higher the level of LTPA the lower mean BP across all levels of OPA were, but only among those not using anti-hypertensives. The prospective analysis showed occupational lifting to increase the risk of hypertension, among workers aged ≥ 50 years, or reporting light to moderate LTPA. Conclusions This study finds positive associations between occupational lifting and risk for hypertension among workers aged ≥ 50 years. Further research on the association between occupational lifting and precursors of cardiovascular disease are needed before recommendations for occupational lifting and cardiovascular health can be established.

2021 ◽  
Vol 42 (15) ◽  
pp. 1499-1511 ◽  
Author(s):  
Andreas Holtermann ◽  
Peter Schnohr ◽  
Børge Grønne Nordestgaard ◽  
Jacob Louis Marott

Abstract Aims  Leisure time physical activity associates with reduced risk of cardiovascular disease and all-cause mortality, while these relationships for occupational physical activity are unclear. We tested the hypothesis that leisure time physical activity associates with reduced major adverse cardiovascular events (MACE) and all-cause mortality risk, while occupational physical activity associates with increased risks. Methods and results  We studied 104 046 women and men aged 20–100 years in the Copenhagen General Population Study with baseline measurements in 2003–2014 and median 10-year follow-up. Both leisure and occupational physical activity were based on self-report with four response categories. We observed 7913 (7.6%) MACE and 9846 (9.5%) deaths from all causes. Compared to low leisure time physical activity, multivariable adjusted (for lifestyle, health, living conditions, and socioeconomic factors) hazard ratios for MACE were 0.86 (0.78–0.96) for moderate, 0.77 (0.69–0.86) for high, and 0.85 (0.73–0.98) for very high activity; corresponding values for higher occupational physical activity were 1.04 (0.95–1.14), 1.15 (1.04–1.28), and 1.35 (1.14–1.59), respectively. For all-cause mortality, corresponding hazard ratios for higher leisure time physical activity were 0.74 (0.68–0.81), 0.59 (0.54–0.64), and 0.60 (0.52–0.69), and for higher occupational physical activity 1.06 (0.96–1.16), 1.13 (1.01–1.27), and 1.27 (1.05–1.54), respectively. Similar results were found within strata on lifestyle, health, living conditions, and socioeconomic factors, and when excluding individuals dying within the first 5 years of follow-up. Levels of the two domains of physical activity did not interact on risk of MACE (P = 0.40) or all-cause mortality (P = 0.31). Conclusion  Higher leisure time physical activity associates with reduced MACE and all-cause mortality risk, while higher occupational physical activity associates with increased risks, independent of each other.


Rheumatology ◽  
2014 ◽  
Vol 53 (suppl_1) ◽  
pp. i68-i68 ◽  
Author(s):  
Luke C. Conway ◽  
Blair H. Smith ◽  
Lynne J. Hocking ◽  
Mark M. McGilchrist ◽  
Anna F. Dominiczak ◽  
...  

2021 ◽  
pp. oemed-2020-106948
Author(s):  
Tyler D. Quinn ◽  
Patrick L. Yorio ◽  
Peter M. Smith ◽  
Yongsuk Seo ◽  
Geoffrey P. Whitfield ◽  
...  

BackgroundEmerging evidence, predominately from European and Asian countries, describes opposing effects of occupational physical activity (OPA) and leisure-time physical activity (LTPA) on cardiovascular health. This analysis examined cardiovascular disease (CVD) prevalence associated with OPA and LTPA.MethodsThis cross-sectional analysis of 2015 National Health Interview Survey data (n=16 974) employed logistic regression to estimate odds (OR) of self-reported CVD (coronary heart disease, heart attack, stroke or angina) with self-reported total occupational activity (TOA), occupational exertion (OE), occupational standing and walking (OSW) and LTPA. OPA was measured using two questions: ‘How often does your job involve…’ (1) ‘repeated lifting, pushing, pulling or bending?’ (OE) and (2) ‘standing or walking around?’ (OSW) with responses on a 5-item Likert scale (0=never, 4=always). TOA was categorised similarly after summing OE and OSW scores. LTPA was defined as 0, 1–149 or ≥150 min/week of moderate-to-vigorous activity. All models adjusted for common socioeconomic variables and additional analyses were stratified by sex, smoking status and LTPA.ResultsOdds for CVD were higher when ‘always’ performing TOA (OR 1.99 95% CI 1.12 to 3.53), OE (OR 2.15, 95% CI 1.45 to 3.19) or OSW (OR 1.84, 95% CI 1.07 to 3.17) compared with ‘never’. When restricting to never-smokers, odds for CVD were higher when ‘always’ performing TOA (OR 3.00, 95% CI 1.38 to 6.51) and OE (OR 3.00, 95% CI 1.80 to 5.02) versus ‘never’.ConclusionAssociations of high OPA with CVD were equally apparent across sexes, stronger in lower LTPA levels and stronger in never-smokers. While uncontrolled confounding is still possible, even after extensive adjustment, the seemingly paradoxical adverse associations with OPA and CVD should be investigated further.


2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Saija Mikkilä ◽  
Giovanna Calogiuri ◽  
Nina Emaus ◽  
Bente Morseth

Abstract Introduction Vertebral fractures are common osteoporotic fractures, affecting 2–46% of the population, causing morbidity and increased risk of mortality. Physical activity has beneficial effects for bone health, including increased bone mineral density and reduced hip fractures. However, evidence concerning prevention of vertebral fractures is scarce. Therefore, the aim of this study was to investigate the association between leisure time physical activity and vertebral fracture risk. Methods The data were retrieved from the 2001 and 2007–2008 surveys of the Tromsø Study, a longitudinal population study in Norway. A total of 1904 participants (1030 women and 874 men, age 38–87 yr and 40–87 yr respectively) were included in the cross-sectional analysis (2007–2008). Prospective follow-up data (2001 to 2007) on physical activity were available for 1131 participants (636 women and 495 men, age 32–69 yr and 33–69 yr respectively). Physical activity was assessed by a questionnaire and vertebral fracture by lateral vertebral fracture assessment from dual-energy x-ray absorptiometry scans. Logistic regression was used to examine associations between physical activity and vertebral fracture. Results After controlling for confounders (age, height, weight, smoking, osteoporosis, osteoporosis medication, left hip total bone mineral density, and use of hormones in women only), no cross-sectional associations between physical activity levels and vertebral fracture were observed, OR 1.13 (95% CI: 0.59–2.13), for moderately active women and 1.44 (0.61–3.42) for highly active women, compared with sedentary women. In men, the respective ORs were 1.74 (95% CI: 0.91–3.35) and 1.64 (0.78–3.41). In the prospective analyses, OR for vertebral fracture in women with reduced physical activity was 0.81 (95% CI: 0.18–3.62), 1.24 (95% CI: 0.29–5.26) for increased physical activity and 1.54 (95% CI: 0.43–5.50) for active unchanged physical activity pattern, compared with sedentary unchanged physical activity. In men, the respective ORs were 2.05 (95% CI: 0.57–7.42), 2.23 (95% CI: 0.63–7.87), and 1.81 (95% CI: 0.54–6.02). Subanalyses of women and men ≥50 yr showed similar results. Conclusions Our findings suggest that physical activity does not play a major role in preventing vertebral fractures in Norwegian adults. Future studies may benefit from data on incident vertebral fracture, and objectively measured physical activity.


2018 ◽  
Vol 38 (4) ◽  
pp. 179-186 ◽  
Author(s):  
John C. Spence ◽  
Guy Faulkner ◽  
Eun-Young Lee ◽  
Tanya Berry ◽  
Christine Cameron ◽  
...  

Introduction In this cross-sectional follow-up study, we explored Canadian’s awareness of ParticipACTION and their levels of physical activity (PA) after seven years of campaigns. Methods A population-based survey was conducted with 7282 adults over a period of 14 months from February 2014 to May 2015. The survey consisted of questions on the 2014-2015 Physical Activity Monitor relating to awareness and knowledge of ParticipACTION. Weighted logistic models were constructed to examine whether awareness was associated with PA-related beliefs, intentions, and leisure time physical activity (LTPA). Results Approximately 20% of Canadians reported unprompted awareness of ParticipACTION and 82% reported prompted awareness. Education, income, and having children were significant correlates of awareness among Canadians. The adjusted odds of people being aware of ParticipACTION (prompted and unprompted) were greater if they were more educated (OR = 1.57, 95% CI: 1.04–2.39; OR = 2.00, 95% CI: 1.24–3.24), reported higher income (OR = 3.92, 95% CI: 2.35–6.53; OR = 2.29, 95% CI: 1.44–3.62), and had children (OR = 1.93, 95% CI: 1.40–2.66; OR = 1.70, 95% CI: 1.26–2.30). Furthermore, awareness of ParticipACTION was positively associated with outcome expectations and self-efficacy, and negatively associated with LTPA status. Conclusion Levels of unprompted awareness of ParticipACTION are higher than previously reported and, in comparison to active Canadians, inactive Canadians are more likely to be aware of the organization. Given that it had primarily targeted parents of inactive children over the past seven years, it appears the organization has been partially effective in achieving its communication goals.


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