Human Blood Type Influences the Host-Seeking Behavior and Fecundity of the Asian Malaria Vector Anopheles Stephensi.

Author(s):  
Shahmshad Ahmed Khan ◽  
Nur Faeza Abu Kassim ◽  
Cameron Ewart Webb ◽  
Muhammad Anjum Aqueel ◽  
Saboor Ahmad ◽  
...  

Abstract The nutritional requirements of mosquitoes include both sugar (generally derived from the nectar of flowers) and blood (humans or animals). Mosquitoes express different degrees of preferences towards hosts depending on behavioral, ecological, and physiological factors. These preferences have implications for mosquito-borne disease risk. The present study is directed to reveal the effect of the human blood groups on the fecundity and fertility of the malaria vector Anopheles stephensi. In laboratory tests, mosquitoes were fed on ABO blood groups via artificial membrane feeders, and the level of attraction against different blood groups was tested by the electroantennogram and wind tunnel bioassay under control conditions. Overall, the human blood type had a significant impact on the fecundity and fertility of female An. stephensi. The highest numbers of eggs are laid, in the case of blood group B, (mean (±SD)) 203.19 (9.45) followed by the AB, 105.75 (4.51), and O, 98.8 (3.98). In the case of blood group B, females attain the highest fertility of about 89.98 (5.43%). This study provides novel insight into the ABO host choice of the mosquitoes that are still partially unknown and suggests more personal protection, which is a useful tool for the prevention of malaria.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shahmshad Ahmed Khan ◽  
Nur Faeza Abu Kassim ◽  
Cameron Ewart Webb ◽  
Muhammad Anjum Aqueel ◽  
Saboor Ahmad ◽  
...  

AbstractThe nutritional requirements of mosquitoes include both sugar (generally derived from the nectar of flowers) and blood (humans or animals). Mosquitoes express different degrees of preferences towards hosts depending on behavioral, ecological, and physiological factors. These preferences have implications for mosquito-borne disease risk. The present study is directed to reveal the effect of the human blood groups on the fecundity and fertility of the malaria vector Anopheles stephensi. In laboratory tests, mosquitoes were fed on ABO blood groups via artificial membrane feeders, and the level of attraction against different blood groups was tested by the electroantennogram and wind tunnel bioassay under control conditions. Results indicate that the female mosquitoes had a strong preference towards the blood group B, while in the case of females fed on O blood group had the highest digestibility rate. Overall, the human blood type had a significant impact on the fecundity and fertility of female An. stephensi. The highest numbers of eggs are laid, in the case of blood group B, (mean (± SD)) 216.3 (8.81) followed by the AB, 104.06 (7.67), and O, 98.01 (7.04). In the case of blood group B, females attain the highest fertility of about 92.1 (9.98). This study provides novel insight into the ABO blood type host choice of the mosquitoes that are still partially unknown and suggests encouraging personal protection for relevant individuals within communities at risk, which is a useful tool for preventing malaria where the An. stephensi is present as a dominant vector.


Author(s):  
Kanchan Prakash Pachghare ◽  
Dr. Sandeep V. Rode

It is very crucial to determine human blood groups in an emergency situation. But according to current system, the detection procedure is very slow. At present, human blood groups are determined manually through plate test procedure. It consists of blood collection and mixing with specific reagents in order to determine the blood agglutination. Blood typing is system which basically used to detect specific blood group of human. Investigation of appropriate blood type within short interval of time plays vital role in blood transfusion, donation, accident and other emergency situations. Currently, blood typing tests are performed by technicians in laboratories. But it is monotonous to do with large number of blood samples, require more time to diagnosis and, as these tests carried out manually, it may introduce human error which will be harmful. Hemoglobin (Hb), a very significant parameter for the human body and deficiency of it causes anemia. During pregnancy, menstruation and ICU deficiency of it can be very risky and even caused death. So, it is important to diagnose it continuously. Usually, physicians examine it by conducting a blood test to confirm it is painful, time-consuming and costly. The major concept of this study is to screen Hb levels within a short period of time. This paper focused on recent advances in detection of blood group with hemoglobin, which can classify different blood group within short period of time with great accuracy and calculate its hemoglobin level.


Author(s):  
Inga Tymofiychuk ◽  
Svetlana Semenenko

In ancient times there was blood a symbol of life flow and energy. It was believed that it gives strength. Red paint and wine were used in traditional rites.Blood type is able to tell a lot of interesting things about its "owner" facts. Having information about your own blood type can be better to understand yourself and your body. The purpose of the article. In Article studies on the history of medicine, which form new ones, are considered ideas about the formation of blood groups. The novelty of the study due to the fact that the idea of ​​blood groups from year to year replenished with new data, which encourages the historical sketch. Main part. With increasing population and changing the environment reduces the possibility to get meat food. As a result, this led to the emergence "Vegetarian" second blood group A. Resettlement of peoples in Europe is the reason for the predominance of people with the second blood group there at this time. It is believed that the homeland of the gene of the third group B is located in the foothills of the Himalayas, in present-day India and Pakistan. The fourth blood group AB arose as a result of mixing holders of gene A and carriers of gene B. Today only 6% Europeans have a fourth blood type, which is the youngest in ABO system. The uniqueness of this group in the inheritance of high immunological protection, which is manifested in resistance to autoimmune and allergic diseases. Conclusions. Evolution human is impossible without a systematic change in gene frequencies population. Is evolution continuing now? Thoughts sometimes contradictory. Some believe that man has reached the top evolutionary tree, others disagree with such conclusions.


2024 ◽  
Vol 84 ◽  
Author(s):  
M. Ghafar ◽  
S. Khwaja ◽  
M. Zahid ◽  
S. I. Hussain ◽  
A. Karim ◽  
...  

Abstract The main purpose of this study was to find out a possible association between ABO blood groups or Rh and diabetes mellitus (DM) in the local population of eight (8) different towns of Karachi, Pakistan. For this purpose a survey was carried out in Karachi to have a practical observation of these towns during the period of 9 months from June 2019 to Feb. 2020. Out of eighteen (18) towns of Karachi, samples (N= 584) were collected from only eight (8) Towns of Karachi and gave a code-number to each town. Diabetic group sample was (n1=432) & pre-diabetes sample was (n2 =152). A standard Abbot Company Glucometer for Random Blood Sugar (RBS) and Fasting Blood Sugar (FBS) tests, standard blood anti sera were used for ABO/Rh blood type. Health assessment techniques were performed ethically by taking informed consent from all registered subjects. Finally data was analyzed by SPSS version 20.0. In our current study, the comparison of ABO blood groups frequencies between diabetic and pre-diabetic individuals were carried out. The percentage values of blood Group-B as given as: (32% in DM vs. 31% in pre-diabetics), followed by blood Group-O as: (18% in DM vs. 11% in pre-diabetics). Contrary to Group-“B” & “O”, blood Group-A and Group-AB were distribution percentage higher pre-diabetic as compared to DM patients, as given as: Group-A (32% in pre-diabetics vs. 26% in DM) & Group-AB (26% in pre-diabetics vs. 24% in diabetic’s patients). In addition, percentage distribution of Rh system was also calculated, in which Rh+ve Group was high and more common in DM patients as compared to pre-diabetics; numerically given as: Rh+ve Group (80% in DM vs. 72% in pre-diabetics). Different views and dimensions of the research topic were studied through literature support, some have found no any association and some established a positive association still some were not clear in making a solid conclusion. It is concluded that DM has a positive correlation with ABO blood groups, and people with Group-B have increased susceptibility to DM disease.


PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261432
Author(s):  
Uzma Ishaq ◽  
Asmara Malik ◽  
Jahanzeb Malik ◽  
Asad Mehmood ◽  
Azhar Qureshi ◽  
...  

Introduction Coronavirus disease 2019 (COVID-19) is the ongoing pandemic with multitude of manifestations and association of ABO blood group in South-East Asian population needs to be explored. Methods It was a retrospective study of patients with COVID-19. Blood group A, B, O, and AB were identified in every participant, irrespective of their RH type and allotted groups 1, 2,3, and 4, respectively. Correlation between blood group and lab parameters was presented as histogram distributed among the four groups. Multivariate regression and logistic regression were used for inferential statistics. Results The cohort included 1067 patients: 521 (48.8%) participants had blood group O as the prevalent blood type. Overall, 10.6% COVID-19-related mortality was observed at our center. Mortality was 13.9% in blood group A, 9.5% in group B, 10% in group C, and 10.2% in AB blood group (p = 0.412). IL-6 was elevated in blood group A (median [IQR]: 23.6 [17.5,43.8]), Procalcitonin in blood group B (median [IQR]: 0.54 [0.3,0.7]), D-dimers and CRP in group AB (median [IQR]: 21.5 [9,34]; 24 [9,49], respectively). Regarding severity of COVID-19 disease, no statistical difference was seen between the blood groups. Alteration of the acute phase reactants was not positively associated with any specific blood type. Conclusion In conclusion, this investigation did not show significant association of blood groups with severity and of COVID-19 disease and COVID-19-associated mortality.


Author(s):  
Melek Yanaşık ◽  
Tülin Tunç ◽  
Mukadder Huslu ◽  
Sevgi Kalayoğlu Beşışık

Objective: In humans, 38 different critical blood type classification systems are currently recognized. They differ in frequencies in distinct populations. It is aimed to visualize ABO and Rh(D) groups distribution in Istanbul as having the largest community in Turkey. Method: Volunteered blood donor's data on the automation system were screened retrospectively. Blood donation acceptance criteria were based on the guidelines prepared by the Ministry of Health. ABO and Rh(D) groups were analyzed using column agglutination/gel centrifugation methods. Results: The study covered six years' data between the dates of January 2014 and December 2019, including 136,231 donors. The majority of the donors were found to have blood group A with a frequency of 41.88%(n=57,059). The second most common blood group was group O, and had a frequency of 34.92%(n=47,576). The blood group B (n=20,790;15.26%) and group AB (n=10,806;7.93%) were found to be the rare encountered blood groups. Among the Rh(D) group, 85.02% of the donors were Rh(D) positive. Conclusion: In transfusion medicine, ABO and Rh(D) groups' compatibility is mandatory. According to the monthly and or annual blood products requirement, there are some suggested quantities of blood units to be available at blood centres. Determining the frequency of blood group distribution of populations will help to coordinate the ratio of blood groups to be storaged. The Turkish genetic makeup is a fascinating mixture of European and Asian DNA, necessitates to find out the countries' specific ABO and Rh(D) groups ratio. We compared our results with the previously reported studies performed in different cities of Turkey and the world around. Thus, our research as giving the overall distribution of ABO and Rh(D) groups from the largest city of Turkey reflecting the general ethnic background of the country, would help to the establishment of a databank of ABO and Rh(D) group's ratio.


2013 ◽  
Vol 7 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Tor Gunnar Hugo Onsten ◽  
Sidia Maria Callegari-Jacques ◽  
Luciano Zubaran Goldani

Objective:To analyze the frequency of and odds for and against HIV infection based on ABO blood type in a large sample of blood donors.Background:Coevolution between pathogens and hosts may explain the ABO system of polymorphisms. HIV-infected cells add ABO(H) blood group antigens to the viral envelope. Naturally occurring antibodies against ABO(H) antigens that are present in normal human sera are able to neutralize ABO-expressing HIVin vitro. Blood donors are ideal for studying blood groups and HIV infectionin vivobecause all donors are routinely typed and tested.Methods:All blood donors who donated blood between 1994 and 2010 were tested for HIV (ELISA antibody tests and Western blot test or immunofluorescence testing) and were ABO typed (direct and reverse grouping tests). HIV infection based on the ABO blood group was analyzed using the chi-square test and game theory.Results:The total number of examined blood donors during this period was 271,410, of whom 389 were infected with HIV. B-group donors were more infected than non-B donors (p= 0.006).Conclusions:A more restricted antigen recognition capacity of anti-Galα1-3Gal in blood groups AB and B and a weaker antigen-binding capacity of anti-A antibodies may contribute to a higher frequency of HIV infection in blood group B.


Medicines ◽  
2022 ◽  
Vol 9 (1) ◽  
pp. 3
Author(s):  
Ioannis Tsamesidis ◽  
Evangelia Stalika ◽  
Chinedu O. Egwu ◽  
Agathi Pritsa ◽  
Maria Parpori ◽  
...  

The ‘Blood-Type’ diet advises individuals to eat according to their ABO blood group to improve their health and decrease the risk of chronic diseases. However, the food preferences of individuals with different blood groups have not been examined. The aim of our study was to investigate, in healthy regular blood donors (rBDs), the associations of smoke, alcohol, caffeine, vitamin and fat intake with their different blood groups and if ABO groups could be a potential predictor tool for disease prevention. A total of 329 volunteers were divided into four groups according to their ABO types: Group 1 (A) comprised 141 rBDs; Group 2 (B), 65 rBDs; Group 3 (O), 96 rBDs; and Group 4, 27 rBDs. Additionally, they were divided into two groups according to their rhesus types and their preferences for smoke, too. Dietary intake was assessed using 3-day food recall and the Food Processor computer program for nutrient analysis. Alcohol, caffeine, sugar and Vitamin D consumption were significantly (p < 0.05) higher in the O group. The A group presented statistically significantly (p < 0.05) greater preferences for cholesterol intake and a higher trend for smoking (25%) habits compared with all the other groups, whereas Group B preferred more fatty foods. The blood group AB appeared to be the most controlled food intake group. Regarding the rhesus comparisons, alcohol; caffeine; and Vitamin C, D, E and K consumptions were significantly (p < 0.05) higher in rhesus-positive individuals than their rhesus-negative counterparts. For the non-smoker group, compared with the smokers, a higher consumption of Vitamin D and fibers was found. In conclusion, in the present study, statistically significant correlations of the ABO and rhesus system with some dietary parameters were found, indicating a consequent influence of these preferences on the progression of different diseases.


Author(s):  
Yousef Rasmi ◽  
Fatemeh Kheradmand ◽  
Mohadeseh Nemati ◽  
Leila Mollazadeh` ◽  
MirHossein Seyyed-Mohammadzad ◽  
...  

In the past, the relationship between coronary artery disease (CAD) and been studied extensively. The ABO blood group has a significant effect on homeostasis and is therefore associated with adverse cardiovascular events. This study aimed to determine the distribution of ABO blood group and rhesus (Rh) status (ABO/Rh) in patients with different severity of CAD in Iranian community. A total of 1,236 CAD patients undergoing angiography were evaluated and their ABO/Rh blood type was determined in a study center between February 2005 and December 2010. Of the 1,236 records, only 1,046 medical documents recorded the number of involved vessels. The patients were classified according to the number of significantly affected stenotic vessels into single vessel (1VD), two vessels (2VD), and three vessels (3VD) disease subgroups. A substantially different ABO/Rh blood groups distribution was seen in the examined samples (O: 29.7%, A: 39.7%, B: 22.2%, AB: 8.3%, Rh positivity: 89.2%). The ABO/Rh blood group phenotype distribution in CAD patients with 1VD, 2VD, and 3VD was as follows: 37.5%, 41.3%, and 41.5%, respectively, for group A; 24.1%, 20.5%, and 20.6%, respectively, for group B; 31.2%, 26.8%, and 30.2%, respectively, for group O; 7.1%, 11.4% and 7.7%, respectively, for group AB (p = 0.26), and 88.7%, 90.5%, and 87.6%, respectively, for Rh positivity, (p = 0.47).  In addition, no significant correlation was not found among the ABO/Rh blood group distribution and the number of vessels involved, however, according to the different distribution of ABO/Rh blood group in CAD patients and healthy population, ABO/Rh might have an unknown role in CAD patients. Keywords: Coronary artery disease, Blood group, Stenosis, Vessel, Rhesus.


Author(s):  
Shairoly Singh ◽  
Ishan Arora

Background: In 1901, ABO blood group was the first human blood group system to be discovered by Karl Landsteiner. After that Rh blood grouping was discovered by Landsteiner and Weiner 1941. Since then for blood transfusion purposes, these two systems have proved to be the most important systems. Agglutinins are the antibodies against red blood cell antigens and based on presence of these antigens and agglutinins human blood is divided into four major blood groups A, B, AB and O. Methods: A retrospective study was conducted in the Department of Blood Bank of our college. A total of 600 fit donors were selected in the time period of seven months from 1st March 2017 to 30th September, 2017. The blood samples were obtained by standard procedures of venepuncture. Results: From our study, it is observed that blood group B is commonest with 229 donors (38.16%), followed by A with 173 donors (28.82%), O blood group with 131donors (21.82%) and blood group AB contributes minimum of study subjects, 71 donors (11.82%). Rh+ve donors were 93.83% whereas Rh-ve donors were 6.17% according to our study. Conclusions: The present study is useful in providing information on the status of ABO and Rh-D blood group distribution of Chamba and knowledge of it will help in effective management of regional blood transfusion service of the area. 


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