Comparative Study of the Efficacy of Biofeedback-Assisted Jacobsons Progressive Muscle Relaxation (Jpmr) for Managingmild/Moderate Depression

Author(s):  
Swayamprava prava baral ◽  
Gyanendra Raghuvanshi ◽  
Abhay paliwal

Abstract Biofeedback is the way of gaining greater awareness of physiological functions with a goal of self-regulation. JPMR (Jacobsons progressive muscle relaxation) causes release of tension in the skeletal muscles, neuro-muscular system is thus seen as a mediator in the relief of depressive symptoms. This study aimed to see the Comparative efficacy of Biofeedback assisted JPMR, Escitalopram and Bimodal use of both in management in mild/moderate depression. The study was conducted at Mental hospital, Indore, with a Sample Size of 30 [Group A 10 ; biofeedback ,Group B 10 ; Escitalopram ,Group C 10;both]. 8 sessions of biofeedback assisted JPMR was given to group A and C .Escitalopram was given group B and C. HAM-D and BDI was applied at baseline , 4 weeks and 8 weeks. As per BDI scale scores, Biofeedback assisted JPMR combined with escitalopram has significantly better response than only biofeedback or only Escitalopram in patients of mild to moderate depression. As per HAM-D scale scores, Biofeedback assisted JPMR combined with escitalopram has significantly better response than only biofeedback or only Escitalopram in patients of mild to moderate depression. Thus Biofeedback appears to be a useful adjunctive treatment for mild to moderate depressive episode.

PEDIATRICS ◽  
1989 ◽  
Vol 83 (1) ◽  
pp. 66-71
Author(s):  
Karen Olness ◽  
Timothy Culbert ◽  
Donald Uden

In a prospective randomized controlled study, the possibility that children could regulate their own salivary immunoglobulins was investigated using cyberphysiologic techniques. Fifty-seven children were randomly assigned to one of three groups. Group A subjects learned self-hypnosis with permission to increase immune substances in saliva as they chose; group B subjects learned self-hypnosis with specific suggestions for control of saliva immunoglobulins; group C subjects were given no instructions but received equal attention time. At the first visit, saliva samples (baseline) were collected, and each child looked at a videotape concerning the immune system and was tested with the Stanford Children's Hypnotic Susceptibility Scale. At the second visit, an initial saliva sample was collected prior to 30 minutes of self-hypnosis practice or conversation. At the conclusion of the experiment, a third saliva sample was obtained. Salivary IgA and IgG levels for all groups were stable from the first to the second sampling. Children in group B demonstrated a significant increase in IgA (P < .01) during the experimental period. There were no significant changes in IgG. Stanford Children's Hypnotic Susceptibility Scale scores were stable across groups and did not relate to immunoglobulin changes.


Author(s):  
Manjunath Akki ◽  
Suresh Hakkandi ◽  
Arti Panwar

Manyastambha is described under Nanatmaja Vatavyadhi. It is a condition where, the aggravated Vata get localized in the Manya Pradesha causing symptoms like Stambha and Shoola. Manyastambha can be compared with earliest symptoms of cervical spondylitis. In this condition, patient complaints of neck pain. The neck is held rigidly and neck movements may exacerbate pain. Now a day, Cervical spondylitis is very common in the people who do routine activities like travelling, household work, desk job etc. It can be seen in people as early as 25 years of age. In Manyastambha, Nasya is the main line of treatment. (i.e. Vatakaphahara Nasya). Objectives: To evaluate the comparative efficacy of Guda Sunthi Avapeedana Nasya and Manjistha Guggulu Avpeedana Nasya in Manyastambha (Cervical Spondylitis). Materials and Methods: This is a comparative clinical study conducted to assess the efficacy in Manyastambha. As per the inclusion and exclusion criteria, the patients who fulfill the criteria were randomly selected and equally divided into two groups. Group A - 15 Patients received Guda-Sunthi Avapeedana Nasya. Group B - 15 Patients received Manjistha-Guggulu Avapeedana Nasya. Results and Conclusion: In Group A, 9 patients (60%) showed complete remission and 6 patients (30%) showed marked response. In Group B, 3 patients (20%) showed complete remission, 1 patient (7%) showed marked response. 6 patients (30%) showed moderate response, 4 patients (26%) showed mild response and 1 patient (7%) showed unchanged response.


2020 ◽  
Vol 13 (6) ◽  
pp. 454-459
Author(s):  
Manish Pandey ◽  
Vaibhav Shrivastava ◽  
Vijay Patidar ◽  
Sabby Dias ◽  
Sameer Trivedi

Objective: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is characterized by pelvic pain and voiding symptoms, the management of which is challenging. The present study was designed to assess the efficacy of biofeedback and pelvic-floor relaxation treatment for CP/CPPS. Methods: A total of 84 patients diagnosed with CP/CPPS were randomly assigned to one of the two groups: conventional therapy (group A) and pelvic-floor muscle relaxation and biofeedback (group B). The Biofeedback and Electrical Stimulation apparatus was used for pelvic-floor muscle electrical stimulation and relaxation with biofeedback. National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scores were evaluated at the start of therapy, after 3 months of treatment and at 6 months (3 months after last treatment received). Results: At 3 months, patients in both groups had a significant decrease (improvement in symptoms) in NIH-CPSI scoring. However, at 6 months, only 19 (47.5%) patients in group A maintained a fall in NIH-CPSI score >6 compared with 37 (94.8%) patients in group B ( p<0.05). At 6 months, there was significant decrease in NIH-CPSI score in group B, whereas in group A, scores had increased (worsening of symptoms). Conclusions: Pelvic-floor muscle relaxation and biofeedback training is a safe and effective treatment for CP/CPPS with sustained efficacy.


2017 ◽  
Vol 19 (1) ◽  
pp. 11-14 ◽  
Author(s):  
Gary Birnbaum

Background: Current disease-modifying therapies (DMTs) are of benefit only in people with relapsing forms of multiple sclerosis (RMS). Thus, safely stopping DMTs in people with secondary progressive MS may be possible. Methods: Two groups of patients with MS were studied. Group A consisted of 77 patients with secondary progressive MS and no evidence of acute central nervous system inflammation for 2 to 20 years. These patients were advised to stop DMTs. Group B consisted of 17 individuals with RMS who stopped DMTs on their own. Both groups were evaluated at treatment cessation and for a minimum of 1 year thereafter. Multiple variables were assessed to determine those that predicted recurrent acute disease. Results: Nine patients in group A (11.7%) and ten patients in group B (58.8%) had recurrent acute disease, almost always within 1 to 2 years of stopping treatment. The only variable of significance in group A distinguishing stable and relapsing patients was age (P = .0003), with relapsing patients being younger. Group B patients were younger and had significantly lower Expanded Disability Status Scale scores than group A, with no significant differences in age between relapsed and stable patients. Conclusions: The DMTs can be stopped safely in older patients with MS (≥7 decades) with no evidence of acute disease for 2 years or longer, with an almost 90% probability of remaining free of acute recurrence. The high proportion of untreated patients with RMS experiencing recurrent acute disease is consistent with published data.


2019 ◽  
Vol 17 (1) ◽  
pp. 10-12
Author(s):  
Binod Kumar Mahaseth

Background: Surgical site infection is the most common post-surgical complication in surgical patients. The incidence of surgical site infection varies from 3-20% (or even more) in different part of the world. To date, the best method and material for skin closure has not been recommended by anybody. Triclosan is an antiseptic agent used for coating a suture material to prevent the infections. This case-controlled study was carried out to determine the comparative efficacy of sutures; Objective: This case-controlled study was carried out to determine the comparative efficacy of sutures: vicryl® and vicryl plus® (triclosan, an antiseptic incorporated with suture), in reducing surgical site infection in laparotomy for clean Gyn/Obs operations. Material and method: This case-controlled study was carried out in Dept. Of Gynae/Obs at Nepalgunj Medical College Teaching Hospital, Kohalpur. The period of the study was from Jan 2018 to January 2019. A total of 50 participants were enrolled in the study, who met the inclusion criteria. The patients were divided into two groups A and B, each consisting of 25 patients. The patients were allocated in the groups alternately to remove bias. The Group A consisted of patients where Vicrylplus® (Ethicon, Johnson & Johnson Company, Ahmadabad, India) polyglactin910 with triclosan) was used and Group B consisted of patients where vicryl ® (Ethicon, Johnson & Johnson Company, Ahmadabad, India) polyglactin910 alone) was used. Patients whose abdominal wounds were found infected, pus swab for culture were taken and sent for aerobic culture and sensitivity. All patients received ceftriaxone and metronidazole single dose before operations prophylactically. Result: Surgical site infection ingroup A was 3 cases out of 25 (12%) and in group B it was 6 cases out of 25(24%). Triclosan added polyglactin910 suture found to be statistically non significant concerning prevention of SSI as compared to polyglactin910 (p=0.472). The mean age of the study population was in group A was (29.76±7.47) and in group B was (27.12±7.42).


2014 ◽  
Vol 151 (5) ◽  
pp. 874-879 ◽  
Author(s):  
Li Li ◽  
Jie Feng ◽  
Shu-hua Xie ◽  
Li-cheng Geng

Objective To evaluate the preemptive analgesic effect of submucosal infiltration of ropivacaine for uvulopalatopharyngoplasty. Study Design Randomized controlled trial. Setting Comprehensive clinical center and academic hospital. Subjects and Methods Fifty consecutive male patients scheduled for uvulopalatopharyngoplasty were divided randomly into group A and group B. In group A, 4 mL of 0.33% ropivacaine and normal saline with epinephrine was preincisionally injected under the mucosa on both sides of the tonsillar fossa, soft palate, and the lower part of palatoglossal arch, whereas the upper and middle parts of the palatoglossal arch and the upper part of the palatopharyngeal arch were infiltrated with 2 mL of the same mixture. In group B, an identical volume of normal saline with epinephrine was administered. In both groups, postoperative pain was initially controlled by intravenous morphine titration until patient-controlled analgesia with morphine could be used. Cumulative patient-controlled analgesic morphine consumption; visual analog scale scores at 4, 8, 12, 24, and 48 hours postoperatively at rest and during swallowing; and opioid-related adverse effects were recorded. Results The visual analog score was lower at rest during the 48-hour postoperative period and during swallowing within the first 12 hours for group A versus group B ( P < .05). Patients in group A required 44.1%, 38.2%, and 41.1% less morphine during the first 24 hours, 24 hours to 48 hours, and 48 hours postoperatively, respectively, and fewer patients experienced nausea, vomiting, and pruritus ( P < .05). Conclusion Preemptive submucosal infiltration with 0.33% ropivacaine effectively controlled pain after uvulopalato-pharyngoplasty.


2021 ◽  
Vol 25 (05) ◽  
pp. 921-928
Author(s):  
Ayesha Humayun

This study was conducted to evaluate the comparative efficacy of hyperosmotic sodium bicarbonate (HSB 8.4%), hypertonic saline (HSS 7.5%) and normal saline (NSS 0.9%) solutions associated with experimentally Salmonella-induced diarrhoea in buffalo neonatal calves. For this purpose, 14–17 days old 18 healthy buffalo calves were reared. After 8–12 h of oral administration of Salmonella broth (6.5 × 108 CFU), diarrhoea was induced successfully. Calves were then randomly divided into three equal groups viz., groups A, B and C and treatment was instituted. Group A received NSS (0.9%) @ 60 mL/kg (body weight) B.W, intravenous (IV) once, group B was administered HSS (7.5%) @ 5 mL/kg B.W, IV once and group C instituted with HSB (8.4%) @ 5 mL/kg B.W, IV once. All three groups were additionally treated with ciprofloxacin @ 7 mg/kg B.W, IV bid and flunixin meglumine @ 2 mg/kg B.W, IV tid. Comparative efficacy of all treatment regimens was assessed through haemodynamic measurements, blood gases determination and serum electrolyte analysis. All parameters were noted at baseline (prior to diarrhoea induction), during neonatal diarrhoea, t=3, t=9, t=18, t=36, t=72, t=120, t=168 h after treatment. The HSB treated calves (group C) revived from diarrhoea quickly (within 9 h) and efficiently than NSS (group A) and HSS (group B), exhibited significantly (P < 0.05) enhancement. At t=18 h, values for central venous partial pressure and systemic vascular resistance were 11.67 ± 0.7, 13.67 ± 0.61 and 13.50 ± 0.56 and 1180. 83 ± 6.94, 1180.83 ± 6.94 and 1465.00 ± 6.76 in groups A, B and C, respectively. HSB treated buffalo neonatal calves also showed significant increase in bicarbonate, blood pH, serum electrolytes and partial pressure of venous oxygen. Basis on the results of this study, it was concluded that small-volume administration of HSB profoundly ameliorated deleterious effects of septicaemia and improve haemodynamic stability in Salmonella-induced bubaline neonatal diarrhoea. It provides a practical and economical method to resuscitate dehydrated diarrhoeic calves thus make it convenient to accomplish in on-farm situation. © 2021 Friends Science Publishers


Author(s):  
O Ayanniyi ◽  
O B Ogunkunle ◽  
C E Mbada

Low level LASER therapy (LLLT) and pulsed ultrasound have been shown to relieve pain, promote healing and tissue repair in sport injuries. The objective of this study was to investigate the comparative efficacy of LLLT and pulsed ultrasound in the management of second - degree contusion in sportsmen. This is a 2 group pre-test – post-test quasi – experimental study involving 20 sportsmen, ten were in Group A (LLLT) and ten in Group B (P-US). They were aged between 19 and 30 years with the mean age 24.9 ± 3.28 years and 27.4 ± 3.75 years for the Group A and Group B respectively. Treatment consisted of six sessions, in a period of 2 weeks. Data collected on each participants included age, weight, height, site of injury, pain intensity, swelling, calf girth and range of motion. The result of the study revealed decrease in pain for both LLLT and pulsed ultrasound (p0.05). It was concluded that both therapies are equally effective in the management of pain resulting from second – degree contusion in sportsmen. KEYWORDS: Low level LASER, pulsed ultrasound, second – degree contusions.


Author(s):  
Olatunji-akioye A ◽  
Ojiaka H N ◽  
Samuel E. S

<p><strong>Objective: </strong>Domestication of the Cane rats is on-going globally and might replace the conventional rodents used in biomedical research in future. However, the paucity of information on adequate anaesthesia vis-a-vis xylazine-ketamine drug combination in the male and female Cane rats warranted this study.</p><p><strong>Methods: </strong>Six adult Cane rats {1.8±0.7 kg body weights (bwt.)} assigned into group A (Female) and group B (Male) of three rats each was used for the study. Each animal was premedicated with atropine sulphate (0.05 mg/kg bwt), and later administered xylazine (10 mg/kg bwt) and ketamine (100 mg/kg bwt) intramuscularly. Meanwhile, anaesthetic characteristics and physiologic indices of anaesthesia were monitored.</p><p><strong>Results: </strong>Results obtained showed that the physiologic indices; open eyelids, smooth induction and recovery, skeletal muscle relaxation and somatic analgesia were observed in all the animals, however, the anaesthetic indices; time to induction, time to standing, duration of analgesia and duration of recumbency showed marked sex variations. The mean values for the duration of analgesia and recumbency were significantly elevated (P&lt;0.05) in group B as compared with group A. Similar trend was seen for time to standing, but, it was non-significant (P&gt;005). However, time to induction mean value for group A was non-significantly increased (P&gt;005) when compared with group B. The heart rate, respiratory rate and rectal temperature mean values decreased in both groups non-significantly (P&gt;0.05).<strong></strong></p><p><strong>Conclusion: </strong>Conclusively, the xylazine-ketamine combination produced anaesthesia in Cane rat and the combination is more tolerated in the male Cane rats than the female Cane rats.</p>


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