scholarly journals Therapeutic effect of duloxetine combined with ozone trigger point injection on fibromyalgia---A retrospective observational study

2021 ◽  
Author(s):  
Xiong Chen ◽  
Lizhi ZHOU ◽  
Jingping Mu ◽  
Junti LU ◽  
Jin XIE ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Disorder ◽  
Clinical Efficacy ◽  
Injection Group ◽  
Significant Difference ◽  
Point Injection ◽  
The Difference ◽  
Group D ◽  
Ozone Injection

Abstract ImportanceFibromyalgia (FM) is a common clinical chronic disease, mainly manifested as generalized chronic muscle pain and discomfort throughout the body, often accompanied by various emotional disorders such as depression, anxiety, cognitive impairment and sleep disorder, which seriously affects the quality of life of patients. However, there has not been adequately good treatment methods in clinically, so it is urgent to seek a better treatment method. In this study, duloxetine combined with ozone pain point injection was used to treat FM patients, and the clinical efficacy of the patients was observed.ObjectiveTo determine whether duloxetine combined with ozone pain point injection is safe and efficacious in the treatment of Fibromyalgia.MethodsAccording to the final treatment plan selection, the patients diagnosed with FM in the Pain Department of Shiyan Taihe Hospital, were selected from July 2017 to July 2020. After communication and written consent, 66 patients were injected with drugs and ozone pain point. Actually 60 cases finished the study procedure and follow-up. The age ranged from 22 to 57 years, and the course of the disease ranged from 2 to 8 years. In this study, a crossover design was adopted, and random number table method was used to enter the group. The patients were randomly divided into duloxetine group (group D), ozone injection group (group O) and duloxetine-ozone injection group (group D+O), with 20 patients in each group. Each group was given corresponding treatment. VAS, FIQ, PSQI and HAMD scales were used to evaluate and calculate the number of pain points, so as to observe and evaluate the clinical efficacy of patients.ResultsIn terms of pain, there was no significant difference among the groups before treatment. After 2 weeks and 4 weeks of treatment, the VAS scores in each group were significantly lower than before intervention (F=324.365 P < 0.05). The number of pain points in each group was significantly lower than before intervention, and the difference was statistically significant (F=514.046 P &lt; 0.05). It was observed that the analgesic effect of duloxetine combined with ozone pain point injection in the treatment of fibromyalgia was better than that of single therapy. There was no significant difference in quality of life among the groups before treatment. After 2 weeks and 4 weeks of treatment, the FIQ of each group was significantly lower than that before intervention, and the difference was statistically significant (F = 324.365, P<0.05). It was observed that duloxetine combined with ozone pain point injection for fibromyalgia significantly improved the quality of life of patients, especially in terms of improving sleep, compared with treatment alone. At the end of 4 weeks of treatment, HAMD scores for depressive symptoms were significantly lower in all 3 groups than before intervention (F=1079.961, P<0.05), and loxetine combined with ozone pain point injection for fibromyalgia had a more significant antidepressant effect (F=5.089, P <0.05).ConclusionThis study confirmed that duloxetine combined with ozone pain-point injection can effectively relieve pain in patients with FM, significantly improve the accompanying symptoms of sleep disorder and depression, and improve the quality of life of patients, which is worthy of clinical promotion.

scholarly journals Impact of the Allergic Asthma on Foot Health-Related Quality of Life and Depression: A Novel Case-Control Research

Medicina ◽  
2019 ◽  
Vol 55 (5) ◽  
pp. 124
Author(s):  
Daniel López-López ◽  
Roi Painceira-Villar ◽  
Vanesa García-Paz ◽  
Ricardo Becerro-de-Bengoa-Vallejo ◽  
Marta Elena Losa-Iglesias ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Allergic Asthma ◽  
Healthy Subjects ◽  
Total Sample ◽  
Foot Health ◽  
Significant Difference ◽  
Control Research ◽  
Health Related ◽  
The Difference

Background: Asthma may be considered as a non-communicable condition associated with higher bronchial responsiveness that may impair quality of life (QoL). Purpose: The research aim was to compare scores of depression, as well as general and foot health-related QoL, in patients who suffered from asthma with respect to healthy subjects. Methods: A total sample of 152 subjects, median age of 37.00 ± 16.00 years, were recruited from a respiratory and allergy department of a hospital and divided into patients with asthma (n = 76) and healthy subjects (n = 76). The scores of the Spanish foot health status questionnaire (SFHSQ) domains as well as the Spanish Beck’s Depression Inventory (BDI) scores and categories were collected. Results: The only statistically significant difference (p < 0.05) was shown for the difference of the FHSQ footwear domain establishing that patients who suffered from asthma presented a worse QoL related to foot health for footwear (lower FHSQ scores) compared to healthy matched-paired participants (higher FHSQ scores). Regarding the rest of the outcome measurements, there were no statistically significant differences (p > 0.05) for the other FHSQ domains scores as well as the BDI scores and categories. Conclusions: Patients with allergic asthma presented impairment of the QoL related to foot health for footwear, which seemed to be linked to the presence of asthma.

scholarly journals Efektivitas Pemberian Edukasi Berbasis Audiovisual dan Tutorial Tentang Antiretroviral (ARV) Terhadap Kepatuhan Pengobatan pada Pasien HIV/AIDS di Klinik Teratai Rumah Sakit Hasan Sadikin Bandung Tahun 2016

2017 ◽  
Vol 3 (2) ◽  
pp. 38
Author(s):  
Sinta Fresia
Keyword(s):  
Quality Of Life ◽  
Control Group ◽  
Research Use ◽  
Social And Emotional ◽  
Number Of Patients ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Difference ◽  
Hiv Aids

Abstrak Latar Belakang : Terjadinya peningkatan jumlah pasien HIV/AIDS dan rendahnya kualitas hidup pasien HIV/AIDS menimbulkan masalah yang cukup luas pada individu yang terinfeksi yakni masalah fisik, social dan emosional.Untuk meningkatkan kualitas dan harapan hidup pasien HIV/AIDS harus mendapatkan terapi Antiretrovirus (ARV) seumur hidup dan dibutuhkan pengawasan terhadap kepatuhan minum obat.Oleh karena itu pasien HIV/AIDS membutuhkan edukasi untuk meningkatkan kepatuhan minum obat dengan metode terbaru yaitu tutorial dan audiovisual.Tujuan penelitian ini untuk menganalisa perbedaan efektivitas pemberian edukasi berbasis audiovisual dan tutorial tentang ARV terhadap kepatuhan pengobatan pasien HIV/ AIDS. Metode : Penelitian ini menggunakan desain Quasi eksperimental dengan rancangan pretest-posttes design without control group.Jumlah sampel 27 responden dibagi 3 kelompok dengan 3 perlakuan berbeda.Masing-masing 9 responden diberikan edukasi dengan metode audiovisual, tutorial, audiovisual dan tutorial.Penelitian dilakukan di Klinik Teratai Rumah Sakit Hasan Sadikin Bandung pada bulan Mei-Juni 2016. Hasil : Ada perbedaan rata-rata mean kepatuhan edukasi dengan audiovisual 2,444, (Pvalue=0,003, 95% CI=1,107-3,782), edukasi dengan metode tutorial perbedaan mean 1,556 (Pvalue=0,023, 95% CI=1,274-2,837), edukasi dengan audiovisual dan tutorial didapatkan perbedaan mean 3,667 (Pvalue=0,003, 95% CI=1,670-5,664). Kesimpulan : Terdapat perbedaan yang significant rata-rata kepatuhan pada masing-masing kelompok intervensi edukasi.Kombinasi edukasi berbasis audiovisual dan tutorial memberikan hasil yang paling baik. Abstract Background : An increasing number of patients with HIV/AIDS and low quality of life of patients with HIV/AIDS cause considerable problems in individuals infected area.There are physical, social and emotional problems.To improve the quality of life of receive antiretroviral (ARV) therapy for life.This requires adherence and supervision taking medication. There fore urgently needed education to improve adherence with the latest audiovisual and tutorial methods. The purpose of this research is to analyze the difference effectiveness of education based audiovisual and tutorial method on ARV treatment adherence with HIV/AIDS patients.Methods : This research use quasi experimental design with pretest and posttest without control group. The numbers of sample in this research is 27 sample. Responden group divided into three different education methode. 9 responden in audiovisual methode,9 responden in tutorial methode and 9 responden in audiovisual and tutorial methode. The study was conducted at the Clinic Teratai Hasan Sadikin Hospital in May-June, 2016. Results : There is a diference in average adherence. In audiovisual methode mean 2,444 (Pvalue=0,003, 95% CI=1,107-3,782), tutorial methode 1,556(Pvalue=0,023, 95% CI=1,274-2,837), audiovisual and tutorial methode mean 3,667 (Pvalue =0,003, 95% CI=1,670-5,664).Conclusion : There is a significant difference in the average adherence in difference methode.Especially in audiovisual and tutorial methode. The combination of audiovisual and tutorial-based education gives the best results

Quality of life in parents of children with attention-deficit-hyperactivity disorder

2017 ◽  
Vol 41 (S1) ◽  
pp. S454-S454
Author(s):  
K. Khemakhem ◽  
C. Sahnoun ◽  
H. Ayadi ◽  
J. Boudabbous ◽  
L. Cherif ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Bodily Pain ◽  
Control Sample ◽  
Child And Adolescent Psychiatry ◽  
Cross Sectional ◽  
Children With Adhd ◽  
Significant Difference ◽  
The Difference

AimThe aim of our study was to investigate and compare the quality of life of parents of children with ADHD and parents of children within psychiatric troubles.MethodsWe conducted a cross sectional and comparative study, on 20 families of children with ADHD, followed in child and adolescent psychiatry department of Sfax, Tunisia, and 20 control families. We used the Short Form Health Survey (SF 36) translated and validated in Arabic to evaluate the quality of life of the parents of the two groups.ResultsThe average age of the patients of our survey was 9 years 8 months with a predominance of boys. We objectified a significant difference between the overall scores of the quality of life of parents of children with ADHD and the control sample. A highly significant difference was noted in the following areas: mental health, bodily pain and social functioning. The difference was significant in vitality score. The difference was not significant in 4 scores: general health, physical functioning, role physical, and role emotional.ConclusionFamilies with a child with ADHD have many challenges which impact certainly in their quality of life. As a child and adolescent's psychiatrics, we should be aware of these consequences in order to help the parents to improve their quality of life.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Study of the difference in quality of life and caregiver burden among patients with schizophrenia and rheumatoid arthritis

2021 ◽  
Author(s):  
Shaista Shaban ◽  
Mohd Abrar Ahmad Guroo ◽  
Racheal Bashir
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Caregiver Burden ◽  
World Health ◽  
Physical Domain ◽  
World Health Organization Quality ◽  
Significant Difference ◽  
Schizophrenic Patients ◽  
The Difference

Background: Quality of life (QOL) is a measure to see an individual’s adaptation and feeling of wellbeing and adjustment with the surroundings. Schizophrenia and rheumatoid arthritis (RA) both are chronic and disabling disorders supposed to have significant effect on quality of life. Also chronicity and disability of these disorders can be directly proportional to the caregiver burden.Methods: Comparative study assessing quality of life and caregiver burden between persons with schizophrenia and RA.Results: 50% of the schizophrenia group as well as the RA group were unemployed, suggesting the magnitude of the disability levels caused by the illness. Only 33% of patients with schizophrenia were married, unlike patients with RA where 83% were married. Of all the four domains of the World Health Organization quality of life instrument (WHO-QOL BREF) both the groups scored highest in the physical domain and least in the psychological domain and the difference between the two groups was not statistically significant in all the four domains. Burden among the caregivers of schizophrenic patients was comparatively high on BAS than caregivers of rheumatoid arthritis. The mean duration of illness in patients with schizophrenia was significantly higher than patients with RA.Conclusions: RA is a chronic disorder and physical in nature with full insight in the patients. While as schizophrenia is characterized as a chronic mental illness with poor prognosis and no insight. QOL is expected to be less in schizophrenic patients. There is no significant difference in QOL except in physical domain in which patients with schizophrenia scored significantly better than patients with RA. The social domain of QOL was the only one in which schizophrenic patients did poorly, though not statistically significant. Also care giver burden was more among caregivers of schizophrenic patients and that can be attributed to lack of insight.

scholarly journals Comparing the Effect of Dienogest and OCPS on Pain and Quality of Life in Women with Endometriosis: A Randomized, Double-Blind, Placebo-Controlled Trial

2021 ◽  
Vol 24 (9) ◽  
pp. 670-677
Author(s):  
Gelareh Niakan ◽  
Samaneh Rokhgireh ◽  
Majid Ebrahimpour ◽  
Abolfazl Mehdizadeh Kashi
Keyword(s):  
Quality Of Life ◽  
Pelvic Pain ◽  
Controlled Trial ◽  
Primary Objective ◽  
Secondary Outcome ◽  
Double Blind ◽  
Oral Contraceptive Pills ◽  
Significant Difference ◽  
The Difference

Background: Endometriosis is an estrogen-dependent disease that adversely affects women’s quality of life (QOL). We aimed to compare the effect of dienogest and oral contraceptive pills (OCPs) on pain and QOL in women with endometriosis. Methods: This randomized double-blind trial was conducted at Rasoul-e-Akram hospital, affiliated to Iran University of Medical Sciences, Tehran, Iran, from March 2018 to March 2020, on women with severe endometriosis confirmed by laparoscopic surgery. Ninety patients were randomly given either dienogest (Vissane 2 mg tablet; n = 30), or OCPs (LD; n = 30), or placebo (n = 30) daily for 12 weeks. The primary objective of this study was to evaluate the patient’s pain including dyspareunia, dysuria, dyschezia, and pelvic pain. The secondary outcome was considered as a change in patients’ QOL score. Results: The mean age of population was 32.99 ± 7.1 years. There was no significant difference in the three groups regarding baseline characteristics. Pelvic pain was significantly reduced, while the effect of medication on dysuria and dyschezia was not significant. The overall QOL score between the control and dienogest (P = 0.02) and OCPs groups (P = 0.001) was significantly different; however, the difference was not significant between the two intervention groups Conclusion: The finding of the present study revealed that there is no difference in the efficacy of dienogest and OCPs in management of pain and the QOL. But there was a significant difference between the placebo and intervention groups.

scholarly journals The effectiveness of acceptance and commitment therapy on perceived stress, resilience, and the quality of life in thalassemia major patients

2019 ◽  
Vol 21 (2) ◽  
pp. 91-97
Author(s):  
Fariborz Jabbarifard ◽  
Tayebeh Sharifi ◽  
Kamal Solati ◽  
Ahmad Ghazanfari
Keyword(s):  
Quality Of Life ◽  
Perceived Stress ◽  
Thalassemia Major ◽  
Control Group ◽  
Stress Resilience ◽  
Acceptance And Commitment ◽  
Significant Difference ◽  
The Difference ◽  
And Control

Background and aims: The present study aimed to determine the effect of acceptance and commitment therapy on perceived stress, resilience, and the quality of life in thalassemia major patients in Lordegan during 2015-2016. Methods: This semi-experimental study used the pre-test and post-test designs with a control group and period. The samples included 40 patients with thalassemia major who referred to Lordegan Shohada hospital, were selected by the purposeful sampling technique based on the inclusion and exclusion criteria, and were randomly assigned to experimental and control groups. The experimental group received eight-week sessions of the acceptance and commitment-based therapy, while the control group received no intervention until the end of the study. The data were collected by the perceived stress questionnaire (Cohen et al), Researcher Conner and Davison Resilience Scale, and the World Health Organization Quality of Life (SF-26). Finally, the obtained data were analyzed using the SPSS software, repeated measure, and covariance tests Results: The results showed that there was a significant difference between the experimental and control groups in terms of the perceived stress, resilience, and the quality of life (P<0.001). In addition, based on the results, 66% of the changes in the perceived stress scores, 81% of the difference in the resiliency scores, and 75% of the difference in the quality of life scores were related to the impact of therapy based on the acceptance and group commitment. Further, the results of the analysis variance of the internal group revealed that the effect of therapy based on the acceptance and commitment on the perceived stress, resilience, and the quality of life had a significant difference in pretest, posttest, and follow-up stages. Conclusion: In general, the therapy based on the acceptance and commitment is found to be a useful practice in reducing the perceived stress while increasing the resilience and improving the quality of life in patients with thalassemia major.

scholarly journals Effect of Continuous Nursing Intervention of Artificial Intelligence on Discharged Patients after Heart Valve Replacement and Application of Omaha System (Preprint)

2020 ◽  
Author(s):  
Jing Zhang ◽  
Qiong Zhou ◽  
George Nelson
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Statistical Significance ◽  
Control Group ◽  
Observation Group ◽  
Health Status Questionnaire ◽  
Significant Difference ◽  
Omaha System ◽  
The Difference

UNSTRUCTURED The purpose of this study is to explore the effect of continuous nursing system of artificial intelligence (AI) on patients discharged from hospital after heart valve replacement (HVR) and the application value of Omaha system. The patients undergoing HVR were taken as the research objects and divided into control group (routine nursing) and observation group (continuous nursing). Through the continuous nursing system of AI, the patients discharged from the hospital were monitored remotely, and the vital signs of patients were analyzed by AI. Different nursing methods were used to intervene the patients. Nursing evaluation data were used for nursing evaluation of patients undergoing HVR. Activity of Daily Life Scale (ADL) was used to evaluate patients' daily living ability, health status questionnaire was used to evaluate patients' health status, and World Health Organization Quality of Life-Brief version (WHOQOL-BREF) was used to evaluate patients' quality of life. The results showed that, before intervention, there was no significant difference in the scores of ADL between the control group and the observation group, with no statistical significance (P > 0.05). After intervention, the scores of ADL in the observation group were higher than those in the control group (P < 0.05), and the differences were statistically significant (P < 0.05); before intervention, the scores of ADL in the control group were higher than those in the control group, with statistical significance (P < 0.05). Before intervention, there was no significant difference in the health status questionnaire score between the control group and the observation group, without statistical significance (P > 0.05). After intervention, the health status questionnaire score of the observation group was higher than that of the control group, and the difference was statistically significant (P < 0.05). Before intervention, there was no significant difference in WHO quality of life evaluation score between the control group and the observation group, without statistical significance (P > 0.05). After intervention, the WHO quality of life evaluation score of the observation group was higher than that of the control group, and the difference was statistically significant (P < 0.05). After intervention, the KBS evaluation of nursing problem outcomes in the observation group was higher than that before intervention, and the difference was statistically significant (P < 0.05). In conclusion, the continuous nursing system of AI based on Omaha system can effectively evaluate the nursing problems of patients after discharge and improve the quality of life of patients, which has important application value.

scholarly journals Mood, Disability, and Quality of Life among a Subgroup of Rheumatoid Arthritis Individuals with Experiential Avoidance and Anxiety Sensitivity

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
S. Mehta ◽  
D. Rice ◽  
S. Janzen ◽  
J. E. Pope ◽  
M. Harth ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Cluster Analysis ◽  
Experiential Avoidance ◽  
Cluster Membership ◽  
Significant Difference ◽  
Low Levels ◽  
The Difference ◽  
Cluster 2

Objective.The current study aimed to identify and characterize distinct RA subgroups based on their level of EA and AS and compares the difference among the subgroups in mood, disability, and quality of life.Methods.Individuals with chronic pain for at least 3 months were recruited from an academic rheumatoid clinic. Participants were assessed for demographic, psychosocial, and personality measures. A two-step cluster analysis was conducted to identify distinct subgroups of patients. Differences in clinical outcomes were compared using the Multivariate ANOVA based on cluster membership.Results.From a total of 223 participants, three distinct subgroups were formed based on cluster analysis. Cluster 1 (N=78) included those with low levels of both EA and AS. Cluster 2 (N=81) consisted of individuals with moderate levels of EA and low levels AS. Cluster 3 (N=64) included those with moderate levels of EA and high AS. Compared to those in Cluster 1, those in Cluster 3 had significantly higher levels of mood impairment and disability and lower quality of life (p<0.05). Significantly lower levels of mood impairment were seen in Cluster 1 compared to Cluster 2 (p<0.05). However, no significant difference in disability or quality of life was seen between the two groups.Conclusions.The three subgroups differed significantly in levels of impairment in mood, disability, and quality of life. However, levels of EA had a greater impact on disability and quality of life than AS.

scholarly journals SOCIAL SUPPORT FOR THE QUALITY OF LIFE POSTPARTUM MOTHERS IN SUKODONO SUBDISTRICT SRAGEN REGENCY

2018 ◽  
Vol 1 (1) ◽  
pp. 45
Author(s):  
Faizah Betty Rahayuningsih ◽  
Endang Zulaicha S
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Repeated Measure ◽  
Cross Sectional ◽  
The Social ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design ◽  
Postpartum Mothers

Introduction: Postpartum period is often considered as temporary or unimportant thing. Thus, the postpartum treatment becomes the ignored aspect from the women's health. The social support is important for mother's and child's prosperity. This research is aimed to examine the difference and the influence of social support score and the quality of life postpartum mothers by home visit 1, 2, and 3. Method: This research employs cross sectional design with longitudinal repeated measure design. The sample of this research was postpartum mothers that give birth in the village of Sukodono subdistrict area from 3 to 40 days. The sample is selected by purposive sampling. Results: There is no significant difference of mean between husband's, parents', parents-in-law's, and relative's support (p > 0.05). There is no significant difference between the quality of life postpartum mother (p > 0.05). The regression equality of social support to quality of life pospartum mother in K1, K2, and K3 were 0,157 + 0.702*husband's support, 0.099 + 0.370*husband's support – 0.674*relative's support, and 0,123+0,0674*husband's support-0,633*relative's support, respectively. Discussion. Husband's support increase quality of life pospartum mother. This is suggested to plan education in-service about the important of social support after giving birth for midwife or nurse that has role to service the mothers. Giving the education of postpartum preparation is not only for the mothers, but also for their husband. Keywords: relative's support, quality of life, postpartum

scholarly journals Quality Of Life and Self-Esteem among People Living With HIV/AIDS

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Mr. Chandrakanth.B.K ◽  
Dr. Shanmuk Kamble
Keyword(s):  
Quality Of Life ◽  
Self Esteem ◽  
People Living With Hiv ◽  
Care And Support ◽  
District Hospitals ◽  
Significant Difference ◽  
The Difference ◽  
Living With Hiv ◽  
Hiv Aids

Purpose of this study is to investigate the difference in quality of life and self-esteem of People living with HIV/AIDS. 2X2 Research design was applied, among a sample of 120 HIV-infected persons receiving treatment, care, and support from district hospitals of Karnataka state. QOL was assessed using the HAT (QOL)-26 tools, and self-esteem scale was used. Results found that there is significant difference in quality of life among people living with HIV / AIDS, and there is significant difference in self-esteem among people living HIV/AIDS. It is also found that there is significant and positive correlation between quality of life and self-esteem among people living with HIV/AIDS.

Sign in / Sign up

Export Citation Format

Share Document