scholarly journals DETERMINATION OF TECHNOLOGICAL PARAMETERS AND INDICATORS OF THE QUALITY OF NEW HERBAL COLLECTION

2018 ◽  
Vol 6 ◽  
pp. 61-68 ◽  
Author(s):  
Anna Kriukova ◽  
Inna Vladymyrova
Keyword(s):  
Rheumatic Diseases ◽  
Maximum Yield ◽  
Biologically Active ◽  
Raw Material ◽  
Concomitant Treatment ◽  
Technological Parameters ◽  
Anti Inflammatory ◽  
Active Substances

Rheumatic diseases include more than 1000 nosological forms, among which the highest incidence is osteoarthritis, rheumatoid arthritis and osteoporosis. The predominantly advanced age, the presence of comorbid diseases, the duration of the course of the disease and the need for concomitant treatment complicate the conduct of anti-inflammatory and analgesic therapy in such patients. Herbal medicines, in particular in the form of doses, due to the mildness of the action and the absence of significant side effects, can be used in the complex therapy of the acute period of rheumatic diseases, as well as for the prevention of relapse. The aim of the presented work was to develop the composition, technology and determination of the quality indices of herbal collection, which reveals analgesic and anti-inflammatory properties and can be used for the prophylaxis and auxiliary therapy of a number of conditions in rheumatology. Materials and methods. In the course of research, the methods used in the State Pharmacopoeia of Ukraine 2.0 (SPHU) were used. Results. As a result of the analysis of literary data and our own experimental studies on the chemical composition and pharmacological activity of certain types of medicinal plant material, we have developed herbal collection that is recommended for the treatment and prevention of rheumatic diseases of the joints. Studies have been conducted on the development of quality collection indicators, which guarantee the effectiveness, safety, reproducibility of the imposed collection. The basic technological parameters of the raw material are determined: specific, bulk and volume mass, porosity, degree, degree of shredding. In order to prevent uneven mixing, an optimal degree of grinding of the raw material of the investigated collection, which ranges from 0.20 mm to 0.35 mm, is established, which allows obtaining a homogeneous mixture and contributes to the maximum yield of extractive and active substances. A series of experimental works aimed at studying the influence of the method of infusion (for 15, 30, 45, 60 minutes and until complete cooling) on the quality of the collected water extracts from the collection was conducted. The optimal method for setting the collection for 60 minutes is the best, since the content of extractives and flavonoids in the aqueous extract was highest and amounted to 49.57±0.52 % and 0.52±0.03 % respectively. Conclusions. The composition of the herbal drug was developed: Harpagophyti radiх, Sophoraе alabastra, Valvae fructus Phaseoli vulgaris, Polygoni avicularis herba with the following ratio of components 50: 20: 20:10. The technological parameters of the raw material are studied: specific, volumetric and bulk mass, porosity, singularity of raw materials. The optimum degree of shredding of raw material is established, which helps to maximally remove biologically active substances and extractives. Experimental way is determined the optimal mode of collection, which can be recommended to the consumer to obtain the maximum therapeutic effect.

scholarly journals Insight into the Way the Content of Biologically Active Compounds in Meadowsweet Inflorescences (Filipendula ulmaria (L.) Maxim.) Is Shaped by Phytosociological Habitats

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5172
Author(s):  
Kinga Stawarczyk ◽  
Aleksandra Chrupek ◽  
Agnieszka Sękara ◽  
Michał Gostkowski ◽  
Małgorzata Karbarz
Keyword(s):  
Genetic Material ◽  
Biologically Active ◽  
Raw Material ◽  
Total Phenolic ◽  
Filipendula Ulmaria ◽  
Biochemical Compounds ◽  
Active Chemical ◽  
Insight Into

A collection of herbs from the natural environment remains not only a source of raw material but also provides evidence of chemical differentiation of the local populations. This work aimed at performing a phytosociological analysis of seven different stands of meadowsweet (Filipendula ulmaria (L.) Maxim.) occurrence. A determination of total phenolic compounds and salicylates and the antioxidant activity of dried meadowsweet inflorescences (Flos ulmariae) was also performed. Active chemical compounds in F. ulmaria inflorescences were related to chemotype and diversified between investigated populations. Geographical distance and variation in phytosociological locations affected chemical composition in different ways, shaping the content of biochemical compounds crucial for herbal material quality. The obtained results can be a valuable indicator for Nexo and Baligród populations, which are good genetic material for research, breeding, and cultivation due to their biochemical composition, especially with respect to salicylates, as major compounds of determining market quality of Flos ulmariae.

A new functional food ingredient enriched by Phytoecdisteroids and Polyphenols from quinoa grains (Chenopodium quinoa Willd.)

2021 ◽  
pp. 4321-4328
Author(s):  
Zorin S.N. ◽  
Sidorova Yu. S. ◽  
Petrov N.A. ◽  
Perova I.B. ◽  
Malinkin A.D. ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Functional Food ◽  
Method Development ◽  
Maximum Yield ◽  
Chenopodium Quinoa ◽  
Biologically Active ◽  
Raw Material ◽  
Food Ingredient ◽  
Mass Spectrometric Detector ◽  
Active Substances

Objective: Quinoa grains (Chenopodium quinoa Willd.) contain a large number of secondary metabolites. Phytoecdysteroids and polyphenols, secondary metabolites, are of great interest for research today. The aim of the study is a method development for the extraction of biologically active substances (BAS) from quinoa grains to obtain a functional food ingredient (FFI) enriched with phytoecdysteroids and polyphenols. Materials and methods: The content of phytoecdysteroids at each stage of quinoa extract production was determined by two methods: HPLC with a spectrophotometric detector and HPLC with a mass spectrometer. The content of total polyphenols was determined by the Folin-Ciocalteu method. The flavonoid profile was determined using a liquid chromatography system with a diode array spectrophotometric detector and a triple quadrupole mass spectrometric detector. Results: The chosen technological scheme for the production of FFI can concentrate more than 200 times the major phytoecdysteroid 20-hydroxyecdysone major in quinoa in the final product relative to the raw material. The maximum yield of flavonoids in the final product was observed in cases of 20 and 40% ethanol extraction. Conclusion: These results lead to the conclusion that highly enriched sources of BAS can be obtained using fairly simple technological approaches and commercially available reagents from quinoa grains.

scholarly journals USE OF NON-TRADITIONAL VEGETABLE RAW MATERIALS IN THE TECHNOLOGY OF FLOURY CONFECTIONARY PRODUCTS FOR RESTAURANT ECONOMY ENTERPRISES

2020 ◽  
Vol 1 ◽  
pp. 32-40
Author(s):  
Yuliya Myroshnyk ◽  
Viktor Dotsenko ◽  
Larisa Sharan ◽  
Vita Tsyrulnikova
Keyword(s):  
Raw Materials ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Food Ration ◽  
Product Technology ◽  
Fresh Products ◽  
Vegetable Raw Materials ◽  
Active Substances

Products of biscuit dough are ones of most popular among floury confectionary products that is conditioned by their taste advantages, and ones of constant elements of food rations. Biscuit semi-products are a base of such confectionary products as tarts, fancy cakes, cookies. It is expedient to use supplements of non-traditional raw materials that can not only influence the technological process and quality of ready products, but also enrich them with biologically active substances as additional components of floury confectionary products. The most promising raw material for enriching products of this group is vegetable powders, because fresh products are seasonal and don’t regularly provide the food ration of the population with biologically active substances. The article considers a possibility of using snowball, ashberry and buckthorn powders for making biscuit semi-products. The aim of the work was to study the expedience and technological possibility of using vegetable raw materials in the biscuit semi-product technology. The chemical composition of chosen powders was studied. The influence of vegetable powder on the quality and quantity of cellulose, structural-mechanical and physical properties of dough was established. The expedience of using surface-active substances in the biscuit semi-product technology for improving the quality of ready products was substantiated.

scholarly journals The study on the development of the technology of the Sedum maximum juice as a biogenic stimulator for obtaining medicines

2021 ◽  
pp. 14-20
Author(s):  
O. I. Burban ◽  
L. I. Vyshnevska ◽  
T. M. Zubchenko
Keyword(s):  
Rapid Heating ◽  
Quality Criteria ◽  
Wide Distribution ◽  
Biologically Active ◽  
Raw Material ◽  
Technological Parameters ◽  
Optimal Method ◽  
Pre Treatment ◽  
Color Reactions ◽  
Active Substances

Due to the complex of biologically active substances (BAS) in the native state, juices are becoming increasingly popular in pharmacy and medicine. We were interested in the Sedum maximum plant as a powerful biogenic stimulant. Despite its wide distribution in the world and in Ukraine, plants of the Sedum L. genus are rarely used. The aim of the study is to determine the technological parameters of the process of obtaining juice from Sedum maximum for the development of technology for its production in pharmacy and industrial conditions and further use in pharmacy and medicine. Results. The optimal method of obtaining fresh juice from Sedum maximum grass using a number of technological techniques in the following sequence was substantiated: fermentation of Sedum maximum grass (keeping in a dark cool place (5 ± 3 ºC) for 5 days; pre-treatment of Sedum maximum grass raw material with boiling water; keeping the crushed raw material at a temperature of 5 ± 3 ºC during the day, purification of unclarified juice with rapid heating to 75-78 °C for 30 min followed by rapid cooling and treatment with 95 % ethanol, sedimentation of Sedum maximum grass juice at a temperature of 5 ± 3 ºC followed by stabilization of clarified juice of Sedum maximum grass with ethanol 15% and chloroethane in the amount of 0.5 %. Conclusions. The quality criteria of the obtained Sedum maximum juice were determined: appearance, pH, dry residue, identification by color reactions and quantitative determination by spectrophotometry (sum of tannins, in terms of pyrogalol). Key words: juice; Sedum maximum; technology; biogenic stimulant

scholarly journals DEVELOPMENT AND VALIDATION OF EXPRESS PROCEDURE FOR ISOLATION AND QUANTITATIVE DE-TERMINATION OF WATER-SOLUBLE POLYSACCHARIDES FROM HIGH DEVISIL ROOTS

2020 ◽  
Author(s):  
Nina Alekseyevna Dyakova ◽  
Sergey Petrovich Gaponov ◽  
Aleksey Ivanovich Slivkin
Keyword(s):  
Raw Materials ◽  
Water Soluble ◽  
Biologically Active ◽  
Raw Material ◽  
Ultrasound Frequency ◽  
Treatment Conditions ◽  
Sediment Mass ◽  
Development And Validation ◽  
Active Substances

The aim of the study was to develop and validate an express procedure for the isolation and quantification of water-soluble polysaccharides from high devisyl roots (Ínula helenium L.). In order to accelerate the process of extracting biologically active substances from the roots of high devisil, as well as to increase the yield of water-soluble polysaccharides, it was decided to use an ultrasonic bath. By varying the process parameters, it was possible to select optimal extraction conditions of water-soluble polysaccharides of high-grade roots under ultrasound treatment conditions: raw material grinding 0.5–1.0 mm, temperature – 80 °C, extraction multiplicity – 3, extraction duration – 15 min, ultrasound frequency – 35 kHz, ratio of raw material to extractor 1 g per 15 ml. The proposed technique allows to intensify the process of preparing polysaccharides water-soluble from roots high and to reduce the time spent on it up to 4-5 hours, as well as to increase the yield of the product up to 31.6% in terms of absolutely dry raw materials. The developed method is precise under the conditions of repeatability, correct, stable and has a rather strict linear dependence of the sediment mass on the analysed raw material mass at gravimetric determination of polysaccharides water-soluble in the roots of high devisil. The technique can be used for express analysis of high devasil roots quality, as well as for industrial production of water-soluble polysaccharides from this kind of raw material.

SELECTION OF COMPOSITION AND TECHNOLOGY OF GRANULES WITH GARDEN LEAVE STRAWBERRY EXTRACT DRY

2021 ◽  
pp. 154-161
Author(s):  
Yaborova O.V. ◽  
Zamakhaeva E.A. ◽  
Oleshko O.A.
Keyword(s):  
Quantitative Determination ◽  
Raw Materials ◽  
Food Product ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Leaf Extracts ◽  
Optimal Method ◽  
Active Substances

Garden strawberries (Fragaria ananassa) are widely cultivated on the territory of Russia on industrial plantations and private garden plots to obtain the fruits (berries) of this plant and their use as a valuable food product. When harvesting fruits, other parts of the garden strawberry are not used, however, its vegetative parts are a source of biologically active substances (BAS) and are of interest for the pharmaceutical and cosmetic industries [1, 4]. The biological activity of garden strawberry leaf extracts is due to the presence of secondary metabolites of a phenolic nature; their content in raw materials reaches more than 3% in some samples [2, 3]. Considering that the main group of biologically active substances of this raw material are flavonoids, the Department of Pharmacognosy with a course of botany conducted research to develop a method for quantitative determination of the amount of flavonoids in terms of rutin. Spectrophotometry was chosen as the optimal method for assessing the content of this group of substances in medicinal plant raw materials - leaves of garden strawberries, which allows determining the amount of flavonoids in terms of the dominant compound and obtaining reliable and reproducible results of quantitative analysis [8, 11]. The technological properties were studied and a therapeutic dose of dry strawberry extract was proposed, optimal compositions were selected and technologies of sachet-granules with dry strawberry extract were developed. The method for the quantitative determination of flavonoids in terms of rutin was validated. The results of the study can be used in the future in the development of draft regulatory documents for sachet-granules with dry strawberry extract of garden leaves and the study of their pharmacological activity.

scholarly journals The influence of the vegetative stage of Galega orientalis on the quality of haylage prepared from it

2020 ◽  
Vol 222 ◽  
pp. 02019
Author(s):  
Boris Starkovskiy ◽  
Gennadiy Simonov ◽  
Yuliya Malinovskaya ◽  
Aleksandr Simonov
Keyword(s):  
Nutritive Value ◽  
Raw Materials ◽  
Production Costs ◽  
Biologically Active ◽  
Raw Material ◽  
Plant Raw Materials ◽  
Beneficial Impact ◽  
Galega Orientalis ◽  
Active Substances

Studying the effect of plant raw materials on the quality of the finished haylage made of Galega orientalis when preparing it at different vegetative stages of plants. Special attention is paid to haylage in the livestock ration structure because compared to silage it has higher nutritive value and contains more dry matter, protein, sugars, macro- and microelements, as well as biologically active substances. It is worth to note that haylage rations have a beneficial impact on the animal body and the productivity of animals, which, in turn, reduces production costs. it has been proved that the green mass of Galega orientalis is a good raw material for making haylage if the technological requirements for feed preparation are met.

Scientific basis of feeding and keeping poultry

2021 ◽  
Author(s):  
Tamara Okolelova ◽  
Syergyey YEngashyev
Keyword(s):  
Scientific Basis ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Technological Parameters ◽  
Basic Principles ◽  
Nutritional Factors ◽  
Enzyme Preparations ◽  
Active Substances

The book covers the basic principles of nutrient rationing for poultry. The data on the needs of all types of poultry, taking into account age, in nutrients, minerals and biologically active substances are given. The characteristic of the main feed means and rational norms of their inclusion in the compound feed for poultry are given. Modern data on the role of vitamins, macro- and microelements, enzyme preparations, probiotics, prebiotics, phytobiotics, organic acids, antioxidants, fat emulsifiers and other sources of biologically active substances in poultry nutrition are presented. Attention is paid to the main technological parameters of poultry keeping. The nutritional factors that reduce immunity, as well as the causes of the main diseases associated with the quality of feed, with violations in the rationing of nutrient, mineral and biologically active substances, the technology of feeding and keeping poultry, are described, methods of their prevention are given. Criteria for the adequacy of nutrition and maintenance of a bird to its genetic potential are stated. The book is intended for specialists and managers of poultry farms, enterprises of the feed industry, researchers, graduate students and students.

scholarly journals ESTABLISHING THE EQUIPMENT-METHODICAL SUPPORT FOR DETERMINING THE PROPERTIES OF EXTRACTS OF GRAPE POMACE EXTRACTS PRODUCED IN THE SUBCREATIVE WATER ENVIRONMENT

2017 ◽  
Vol 5 ◽  
pp. 18-25
Author(s):  
Valeri Sukmanov ◽  
Anatoliy Ukrainets ◽  
Volodymyr Zavialov ◽  
Andrii Marynin
Keyword(s):  
High Pressure ◽  
Subcritical Water ◽  
Maximum Yield ◽  
Water Environment ◽  
Chemical Properties ◽  
Grape Pomace ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Active Substances

Research objective: development of a high-pressure reactor for researching the process of extraction of grape pomace by the subcritical water and determining the parameters, providing the maximum yield of various target products – biologically active substances; formation of methodological support for raw material preparation, qualitative and quantitative analysis of extracts, produced by the subcritical extraction. As a result of simulation in the ANSYS system of the stress-strain state of the walls of the reactor chamber and a set of calculation operations, a high-pressure reactor was created that meets the requirements. The formed methodical complex for determining the physicochemical properties of extracts and the content of various biologically active substances included methods for preparing samples and determining the yield of dry extractive substances, evaluation of extraction of polyphenols (tannic-catechol complex), evaluation of extraction of reducing substances, identification furfural and gallic acids, estimation of free organic acids in terms of tartaric acid, evaluation of antioxidant activity of extracts). This methodological complex allows us to estimate the physico-chemical properties of the extracted biologically active substances.

scholarly journals Phytochemical Analysis of Elaeagnus argentea Leaves

2021 ◽  
Vol 10 (3) ◽  
pp. 95-99
Author(s):  
N. A. Salnikova ◽  
Yu. V. Shur ◽  
A. A. Tsibizova
Keyword(s):  
Ascorbic Acid ◽  
Quantitative Determination ◽  
Raw Materials ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Phytochemical Analysis ◽  
Promising Source ◽  
Active Substances

Introduction. Currently, close attention in the field of pharmacy and medicine is directed to the search for new sources of biologically active substances of various origins, including vegetable. The woody plant Elaeagnus argentea is considered as a promising source. Despite its widespread use in the food industry, folk medicine as an anti-inflammatory, restorative, antimicrobial agent, the chemical composition of this plant has not been sufficiently studied.Aim. Qualitative and quantitative determination of the main groups of biologically active substances (BAS) in the raw material (leaves) of Elaeagnus argentea growing on the territory of the Astrakhan region for further development of a methodology for standardizing the raw material of this plant.Materials and methods. The leaves of Elaeagnus argentea were harvested in the spring in the eastern part of the delta of the Astrakhan region (Volga region). Drying of raw materials was carried out in natural conditions. In the study, unified methods were used: to determine the amount of flavonoids and saponins, the spectrophotometric method was used, ascorbic acid - the titrimetric method. For the analysis of flavonoids in the leaves of Elaeagnus argentea, an aqueous-alcoholic solution of 70 % concentration was used as an extractant. The quantitative content of flavonoids was determined in the obtained raw material extract in terms of luteolin-7-glucoside. The amount of saponins in the leaves of Elaeagnus argentea was determined in terms of oleanolic acid. 96 % ethanol was used as an extractant. The quantitative determination of ascorbic acid in the aqueous extract of crushed raw materials was carried out by titrimetry based on the ability to reduce 2,6-dichlorophenolindophenol.Results and discussion. In the pharmacognostic study of biologically active substances in the leaves of Elaeagnus argentea, the content of ascorbic acid was found to be at least 0.32 %, the amount of flavonoids in terms of luteolin-7-glucoside was at least 1.92 %; saponins - 2.38 %; which indicates the need for a more detailed study of the phytochemical composition of other morphological groups of the plant Elaeagnus argentea growing in the Astrakhan region.Conclusion. The data obtained during the study can be used to confirm the quality of raw materials (leaves) of Elaeagnus argentea. A more detailed study of leaves for the presence of other groups of biologically active substances will make it possible to use the obtained data for the development of regulatory documents for medicinal plant raw materials «Elaeagnus argentea leaves».

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