Metabolomics Study of Isocaloric Different Dietary Patterns on the Life Span in Healthy Population

Over the last three decades, dietary pattern analysis has come to the forefront of nutritional epidemiology, where the combined effects of total diet on health can be examined. Two analytical approaches are commonly used: a priori and a posteriori. Cluster analysis is a commonly used a posteriori approach, where dietary patterns are derived based on differences in mean dietary intake separating individuals into mutually exclusive, non-overlapping groups. This review examines the literature on dietary patterns derived by cluster analysis in adult population groups, focusing, in particular, on methodological considerations, reproducibility, validity and the effect of energy mis-reporting. There is a wealth of research suggesting that the human diet can be described in terms of a limited number of eating patterns in healthy population groups using cluster analysis, where studies have accounted for differences in sex, age, socio-economic status, geographical area and weight status. Furthermore, patterns have been used to explore relationships with health and chronic diseases and more recently with nutritional biomarkers, suggesting that these patterns are biologically meaningful. Overall, it is apparent that consistent trends emerge when using cluster analysis to derive dietary patterns; however, future studies should focus on the inconsistencies in methodology and the effect of energy mis-reporting.

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Cardioprotective diet in Siberian residents: the PURE study

European Heart Journal ◽

10.1093/eurheartj/ehab724.2426 ◽

2021 ◽

Vol 42 (Supplement_1) ◽

Author(s):

D Tsygankova ◽

E D Bazdyrev ◽

E V Indukaeva ◽

G V Artamonova ◽

O L Barbarash

Keyword(s):

Risk Factors ◽

Abdominal Obesity ◽

Dietary Patterns ◽

Dietary Habits ◽

Epidemiologic Study ◽

Principal Component ◽

Healthy Population ◽

Carbohydrate Diet ◽

Vegetable Diet ◽

Obesity And Diabetes

Abstract Introduction Nutrition plays an important role in the prevention of cardiovascular pathology. An appropriate diet helps to prevent the development of arterial hypertension (AH), hypercholesterolemia, obesity and diabetes mellitus (DM). Aim To identify dietary patterns and investigate the relationship between dietary patterns and risk factors for cardiovascular disease in healthy population of Siberia. Materials and methods 1,600 people (age 35–70) were examined for the Prospective Urban and Rural Epidemiologic Study (PURE). Re-examination was carried out after 35.6±2.9 months. Subjects without chronic diseases, with normal blood pressure, lipid and glucose levels, body mass index (BMI) and waist circumference (WC) were selected for the analysis. They accounted for 5.2% of the total number of the responders. Dietary habits were assessed using principal component analysis. Results Three types of dietary patterns have been identified by factor analysis. The first type incorporates the consumption of vegetables, fruits throughout the year (“fruit/vegetable”). The second type includes the consumption of fatty meat, complex carbohydrates and sweets (“protein/carbohydrate”). The third type is comprised of persons who did not belong to any of the previous two types (“mixed”). Most of the responders adhered to the protein/carbohydrate type (42.2%), whereas the fruit/vegetable and mixed types accounted for 28.9% each. Results of the second examination showed that in subjects following the fruit/vegetable diet-37.5% did not have any risk factors, 4.2% developed hypercholesterolemia, 4.2%-hypertriglyceridemia and general obesity, 12.5%-higher levels of low-density lipoprotein (LDL) and 16.7% had abdominal obesity. In protein/carbohydrate diet-71.4% of the responders remained healthy, 8.6% developed hypercholesterolemia, 2.8%-AH and 2.8%-abdominal obesity, 14.3%-a high LDL level. In the mixed diet-58.3% of the responders remained completely healthy, 8.3%-hypercholesterolemia, 12.5%-high LDL cholesterol levels, and 12.5%-abdominal obesity. Logistic regression analysis demonstrated that adherence to the fruit/vegetable type was associated with an higher risk of obesity according to BMI (OR=1.57, CI: 1.27–1.96, p<0.001), WC (OR=1.43, CI: 1.1–1.9, p=0.006), DM (OR=1.27, CI: 1.2–2.2, p=0.046). Adherence to the protein/carbohydrate diet was associated with a lower risk of obesity according to BMI (OR=0.75, CI: 0.6–0.95, p=0.015), WC (OR=0.52, CI: 0.41–0.66, p<0.001), DM (OR=0.66, CI: 0.47–0.93, p=0.018), hypercholesterolemia and hypertriglyceridemia (OR=0.66, CI: 0.52–0.83, p<0.001). Conclusion Three types of diets have been prominent in Siberian residents. The fruit/vegetable diet has been associated with the development of obesity and diabetes, in contrast to the protein/carbohydrate diet. The findings suggest that it is necessary to further study the qualitative characteristics of each type of diet, depending on the physical activity of the respondents. FUNDunding Acknowledgement Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): The study was supported by the Pfizer Inc

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Continuum of Care Following Sports-Related Concussion

American Journal of Speech-Language Pathology ◽

10.1044/2020_ajslp-19-00131 ◽

2020 ◽

Vol 29 (3) ◽

pp. 1389-1403

Author(s):

Jessica Brown ◽

Kelly Knollman-Porter

Keyword(s):

Young Adults ◽

Life Span ◽

Sports Injuries ◽

Continuum Of Care ◽

Medical Professional ◽

Structured Interviews ◽

Youth Athletes ◽

Speech Language Pathologist ◽

History Of ◽

Injury Reporting

Purpose Although guidelines have changed regarding federally mandated concussion practices since their inception, little is known regarding the implementation of such guidelines and the resultant continuum of care for youth athletes participating in recreational or organized sports who incur concussions. Furthermore, data regarding the role of speech-language pathologists in the historic postconcussion care are lacking. Therefore, the purpose of this retrospective study was to investigate the experiences of young adults with history of sports-related concussion as it related to injury reporting and received follow-up care. Method Participants included 13 young adults with history of at least one sports-related concussion across their life span. We implemented a mixed-methods design to collect both quantitative and qualitative information through structured interviews. Participants reported experiencing 42 concussions across the life span—26 subsequent to sports injuries. Results Twenty-three concussions were reported to a parent or medical professional, 14 resulted in a formal diagnosis, and participants received initial medical care for only 10 of the incidents and treatment or services on only two occasions. Participants reported concussions to an athletic trainer least frequently and to parents most frequently. Participants commented that previous experience with concussion reduced the need for seeking treatment or that they were unaware treatments or supports existed postconcussion. Only one concussion incident resulted in the care from a speech-language pathologist. Conclusion The results of the study reported herein shed light on the fidelity of sports-related concussion care management across time. Subsequently, we suggest guidelines related to continuum of care from injury to individualized therapy.

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Knowledge and Skills Needed by Speech-Language Pathologists for Diagnosis, Assessment, and Treatment of Autism Spectrum Disorders Across the Life Span

10.1044/policy.ks2006-00075 ◽

2006 ◽

Cited By ~ 1

Author(s):

Keyword(s):

Autism Spectrum Disorders ◽

Life Span ◽

Autism Spectrum ◽

Speech Language Pathologists ◽

Knowledge And Skills ◽

Assessment And Treatment ◽

Spectrum Disorders

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Tumorigenesis in High-Dose Total Body Irradiated Rhesus Monkeys--A Life Span Study

Toxicologic Pathology ◽

10.1080/01926230309805 ◽

2003 ◽

Vol 31 (2) ◽

pp. 209-213 ◽

Cited By ~ 10

Author(s):

Carel F. Hollander ◽

Chris Zurcher ◽

Johan J. Broerse

Keyword(s):

Life Span ◽

Rhesus Monkeys ◽

High Dose ◽

Life Span Study ◽

Total Body

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Cardiorespiratory fitness is positively associated with both healthy and western dietary pattern in Iranian middle-aged

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000685 ◽

2020 ◽

pp. 1-10

Author(s):

Hossein Shahinfar ◽

Farhang Djafari ◽

Nadia Babaei ◽

Samira Davarzani ◽

Mojdeh Ebaditabar ◽

...

Keyword(s):

Cardiorespiratory Fitness ◽

Dietary Patterns ◽

Dietary Pattern ◽

Principal Component ◽

Total Sample ◽

Linear Regression Models ◽

Middle Aged ◽

Anthropometric Measures ◽

Western Dietary Pattern ◽

Healthy Dietary Pattern

Abstract. Background: The association between dietary patterns and cardiorespiratory fitness (CRF) is not well established. Objective: We sought to investigate association between a posteriori dietary pattern and CRF in middle-aged adults. Design: Adults (n = 276), aged 20–74 years, who were residents of Tehran, Iran were recruited. Diet was assessed by using a validated 168-item semi-quantitative food frequency questionnaire. Principal component analysis was used to derive dietary patterns. Socio-economic status, anthropometric measures, body composition, and blood pressure were recorded. CRF was assessed by using a graded exercise treadmill test. Analysis of variance and linear regression models were used to discern the association between dietary patterns and CRF. Results: Higher scores of the healthy dietary pattern had no association with VO2max (p = 0.13 ). After controlling for potential confounders, VO2max was positively associated across tertiles of healthy dietary patterns (p < 0.001). Higher adherence to the “mixed” dietary pattern was inversely related to VO2max (p < 0.01). After adjusting for confounders, the significant association disappeared (p = 0.14). Higher scores of the “Western” dietary pattern was not associated with VO2max (p = 0.06). However, after controlling for potential confounders, VO2max was positively associated with the “Western” dietary pattern (p = 0.01). A positive linear association between the “healthy” dietary pattern and CRF for the total sample (R2 = 0.02; p < 0.01) were presented. Conclusions: Overall, our findings suggest that higher adherence to a “healthy” and “Western” dietary pattern was positively associated with CRF. However, further studies are required to examine and clarify the causal relationship between dietary patterns and CRF.

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Association of Major Dietary Patterns with General and Abdominal Obesity in Iranian Patients with Type 2 Diabetes Mellitus

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000233 ◽

2015 ◽

Vol 85 (3-4) ◽

pp. 145-155 ◽

Cited By ~ 9

Author(s):

Marjan Ghane Basiri ◽

Gity Sotoudeh ◽

Mahmood Djalali ◽

Mohammad Reza Eshraghian ◽

Neda Noorshahi ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Abdominal Obesity ◽

Dietary Patterns ◽

Dietary Pattern ◽

Diabetic Patients ◽

General Obesity ◽

Healthy Dietary Pattern

Abstract. Background: The aim of this study was to identify dietary patterns associated with general and abdominal obesity in type 2 diabetic patients. Methods: We included 728 patients (35 - 65 years) with type 2 diabetes mellitus in this cross-sectional study. The usual dietary intake of individuals over 1 year was collected using a validated semi-quantitative food frequency questionnaire. Weight, height, and waist circumference were measured according to standard protocol. Results: The two major dietary patterns identified by factor analysis were healthy and unhealthy dietary patterns. After adjustment for potential confounders, subjects in the highest quintile of the healthy dietary pattern scores had a lower odds ratio for the general obesity when compared to the lowest quintile (OR = 0.45, 95 % CI = 0.26 - 0.79, P for trend = 0.02), while patients in the highest quintile of the unhealthy dietary pattern scores had greater odds for the general obesity (OR = 3.2, 95 % CI = 1.8 - 5.9, P for trend < 0.001). There were no significant associations between major dietary patterns and abdominal obesity, even after adjusting for confounding factors. Conclusion: This study shows that in patients with type 2 diabetes mellitus, a healthy dietary pattern is inversely associated and an unhealthy dietary pattern is directly associated with general obesity.

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Conflict Monitoring Across the Life Span

Journal of Psychophysiology ◽

10.1027/0269-8803/a000120 ◽

2014 ◽

Vol 28 (3) ◽

pp. 124-135 ◽

Cited By ~ 5

Author(s):

Daniela Czernochowski

Keyword(s):

Older Adults ◽

Life Span ◽

Age Groups ◽

Conflict Detection ◽

Response Conflict ◽

Conflict Monitoring ◽

Subsequent Performance ◽

Additional Control ◽

Performance Response ◽

Conflict Detection And Resolution

Errors can play a major role for optimizing subsequent performance: Response conflict associated with (near) errors signals the need to recruit additional control resources to minimize future conflict. However, so far it remains open whether children and older adults also adjust their performance as a function of preceding response conflict. To examine the life span development of conflict detection and resolution, response conflict was elicited during a task-switching paradigm. Electrophysiological correlates of conflict detection for correct and incorrect responses and behavioral indices of post-error adjustments were assessed while participants in four age groups were asked to focus on either speed or accuracy. Despite difficulties in resolving response conflict, the ability to detect response conflict as indexed by the Ne/ERN component was expected to mature early and be preserved in older adults. As predicted, reliable Ne/ERN peaks were detected across age groups. However, only for adults Ne/ERN amplitudes associated with errors were larger compared to Nc/CRN amplitudes for correct trials under accuracy instructions, suggesting an ongoing maturation in the ability to differentiate levels of response conflict. Behavioral interference costs were considerable in both children and older adults. Performance for children and older adults deteriorated rather than improved following errors, in line with intact conflict detection, but impaired conflict resolution. Thus, participants in all age groups were able to detect response conflict, but only young adults successfully avoided subsequent conflict by up-regulating control.

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