scholarly journals Inhibition of Proliferation and Migration of Tumor Cells Through Phenylboronic Acid-Functionalized Polyamidoamine-Mediated Delivery of a Therapeutic DNAzyme Dz13 [Corrigendum]

2021 ◽  
Vol Volume 16 ◽  
pp. 8117-8119
Author(s):  
Jiebing Yang ◽  
Jiayuan Zhang ◽  
Jiakai Xing ◽  
Zhiyuan Shi ◽  
Haobo Han ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Phenylboronic Acid ◽  
Inhibition Of Proliferation ◽  
And Migration ◽  
Proliferation And Migration

Inhibition of proliferation and migration of tumor cells through lipoic acid-modified oligoethylenimine-mediated p53 gene delivery

2019 ◽  
Vol 43 (6) ◽  
pp. 2758-2765
Author(s):  
Xiuhui Tang ◽  
Qing Li ◽  
Xiao Liang ◽  
Jiebing Yang ◽  
Ziling Liu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Tumor Cells ◽  
Lipoic Acid ◽  
P53 Gene ◽  
Inhibition Of Proliferation ◽  
And Migration ◽  
Proliferation And Migration

Inhibition of proliferation and migration of tumor cells through lipoic acid-modified oligoethylenimine-mediated p53 gene delivery.

scholarly journals Down-regulated LncR-MALAT1 suppressed cell proliferation and migration by inactivating autophagy in bladder cancer

RSC Advances ◽  
2018 ◽  
Vol 8 (54) ◽  
pp. 31019-31027
Author(s):  
Jiude Qi ◽  
Yanfeng Chu ◽  
Guangyan Zhang ◽  
Hongjun Li ◽  
Dongdong Yang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Bladder Cancer ◽  
Lung Adenocarcinoma ◽  
Tumor Cells ◽  
Cell Proliferation And Migration ◽  
Non Coding Rna ◽  
And Migration ◽  
Long Non Coding Rna ◽  
Proliferation And Migration

Long non-coding RNA-metastasis-associated lung adenocarcinoma transcript (LncR-MALAT) is highly expressed in a variety of tumors, which can affect the progression of tumor cells.

scholarly journals Aberrant CD137 ligand expression induced by GATA6 overexpression promotes tumor progression in cutaneous T-cell lymphoma

Blood ◽  
2018 ◽  
Vol 132 (18) ◽  
pp. 1922-1935 ◽  
Author(s):  
Hiroaki Kamijo ◽  
Tomomitsu Miyagaki ◽  
Naomi Shishido-Takahashi ◽  
Rina Nakajima ◽  
Tomonori Oka ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Tumor Cells ◽  
Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Promote Cell Proliferation ◽  
Cell Proliferation And Migration ◽  
Key Points ◽  
Ligand Expression ◽  
And Migration ◽  
Proliferation And Migration

Key Points Overexpression of GATA6 induces aberrant CD137L expression on tumor cells of CTCL. CD137-CD137L interactions promote cell proliferation and migration in CTCL cells, representing potential therapeutic targets.

scholarly journals Protective Effect of Silymarin against Rapamycin-induced Apoptosis and Proliferation Inhibition in Endothelial Progenitor Cells

2015 ◽  
Vol 10 (2) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Peng Zhang ◽  
Guohua Han ◽  
Pei Gao ◽  
Kun Qiao ◽  
Yusheng Ren ◽  
...  
Keyword(s):  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Mononuclear Cells ◽  
Control Group ◽  
Dependent Manner ◽  
Endothelial Progenitor ◽  
Concentration Dependent Manner ◽  
Inhibition Of Proliferation ◽  
And Migration ◽  
Proliferation And Migration

For this study, peripheral blood samples were collected from human volunteers. Mononuclear cells (MNC) were separated by density centrifugation and were induced to differentiate into endothelial progenitor cells (EPCs) in vitro. Different concentrations of rapamycin and silymarin were introduced to the EPCs over 24 hours and then EPCs were analyzed for proliferation, migration, apoptosis and angiogenesis. Compared with the control group, rapamycin (1, 10, 100 ng/mL) inhibited the proliferation and migration of EPCs in a concentration dependent manner ( P<0.05). Silymarin (50, 100 μg/mL) enhanced the proliferation and migration of EPCs and inhibited apoptosis in a concentration dependent manner ( P<0.05). By adding rapamycin (1 ng/mL) and silymarin (25, 50, 100 μg/mL) over 24 hours, silymarin inhibited the pro-apoptotic effect of rapamycin on EPCs, and reversed the inhibition of proliferation, migration and angiogenesis of EPCs by rapamycin ( P<0.05).

scholarly journals miR-185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

2017 ◽  
Vol 13 (4) ◽  
pp. 2442-2448 ◽  
Author(s):  
Jinpeng He ◽  
Ning Tian ◽  
Yanli Yang ◽  
Liangliang Jin ◽  
Xiu Feng ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Inhibition Of Proliferation ◽  
And Migration ◽  
Proliferation And Migration

Inhibition of proliferation and migration by piceatannol in vascular smooth muscle cells

2009 ◽  
Vol 23 (7) ◽  
pp. 1284-1291 ◽  
Author(s):  
Beobyi Lee ◽  
Eo-Jin Lee ◽  
Dong-Il Kim ◽  
Sung-kyu Park ◽  
Wun-Jae Kim ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Inhibition Of Proliferation ◽  
And Migration ◽  
Proliferation And Migration

scholarly journals Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Nataša Pavlović ◽  
Carlemi Calitz ◽  
Kess Thanapirom ◽  
Guiseppe Mazza ◽  
Krista Rombouts ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Cells ◽  
Cell Activation ◽  
Stellate Cell ◽  
Stellate Cells ◽  
Tumor Burden ◽  
And Migration ◽  
Hcc Cells ◽  
Proliferation And Migration

Hepatocellular carcinoma (HCC) is a liver tumor that usually arises in patients with cirrhosis. Hepatic stellate cells are key players in the progression of HCC, as they create a fibrotic micro-environment and produce growth factors and cytokines that enhance tumor cell proliferation and migration. We assessed the role of endoplasmic reticulum (ER) stress in the cross-talk between stellate cells and HCC cells. Mice with a fibrotic HCC were treated with the IRE1α-inhibitor 4μ8C, which reduced tumor burden and collagen deposition. By co-culturing HCC-cells with stellate cells, we found that HCC-cells activate IREα in stellate cells, thereby contributing to their activation. Inhibiting IRE1α blocked stellate cell activation, which then decreased proliferation and migration of tumor cells in different in vitro 2D and 3D co-cultures. In addition, we also observed cell-line-specific direct effects of inhibiting IRE1α in tumor cells.

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