scholarly journals PREMENSTRUAL SYNDROME: CLINICAL PATTERN, DIAGNOSTICS AND THERAPEUTIC APPROACHES

2017 ◽  
pp. 106-111
Author(s):  
L. P. Guliyeva ◽  
S. V. Yureneva

Premenstrual syndrome (PMS) is a complex, cyclical, polyethiological, multifactorial combination of physical and mental disorders that occur in some women of reproductive age in the second - luteal - phase of the menstrual cycle and negatively affect the woman’s usual lifestyle.Premenstrual dysphoric disorder (PMDD) is a severe form of PMS in which psychoneurological symptoms prevail. For the diagnosis of PMDD, the specific DSM-5 criteria were developed by the American Psychiatric Association according to which the the diagnosis is confirmed by the presence of five or more symptoms in women during the week prior to menstruation and their disappearance a few days after the onset of menstruation. These symptoms are observed for at least two cycles.Treatment of women with PMS/PMDD, first of all, should start with the lifestyle adjustment, inclusion of regular mode rate physical activity into daily activities. The effectiveness of vitamins B6, E and calcium has not been confirmed in studies. First-line drug therapy includes SSRIs or combined oral contraceptives containing drospirenone are prescribed first, then agonists of gonadotropin-releasing hormone.

Author(s):  
Sophie Catteau-Jonard ◽  
Cécile Gallo ◽  
Didier Didier

The polycystic ovary syndrome (PCOS) is the most common cause of anovulation and hyperandrogenism in women, affecting between 5 and 10% of women of reproductive age worldwide (1). Although this difficult topic in endocrine gynaecology is under extensive research, controversies still remain about the pathophysiology, diagnosis, and therapy of PCOS. The PCOS phenotype can be structured in three components: manifestations of anovulation, hyperandrogenism, and the metabolic syndrome (of which hyperinsulinaemia secondary to insulin resistance is the central abnormality). The latter two are addressed in other chapters. Our knowledge about the mechanism of disturbed folliculogenesis in PCOS that is responsible for its reproductive aspects has much increased these last years, thus opening new avenues for the diagnostic and therapeutic approaches.


Author(s):  
Khushboo Jha ◽  
K. Bharathi ◽  
Hetal H. Dave ◽  
Sonu

Menstruation is a normal physiological process in females starting at the age of twelve years and lasts till the age of fifty years. It is a cyclical phenomenon usually occurring every twenty-one to thirty five days and includes uterine bleeding for about three to seven days. Most well adjusted women experience minor psychological and somatic changes for a few days preceding menstruation. These menstrual molimina give way to a sensation of relief and well being once menstruation is established. Most women of reproductive age have some physical discomfort or dysphoria in the weeks before menstruation. Pre-Menstrual Syndrome is one such commonly reported and highly prevalent disorder characterized by constellation of physical, emotional, cognitive and behavioral symptoms. An 18-year-old female patient reported to OPD with the complaints of pain during menses since six years, extreme mood swings, irritability, sudden tearfulness, anger outbursts, nervousness. These symptoms were also associated with vomiting and loose motions. On physical examination, no abnormalities were detected. Mental Status Examination revealed abnormality in mood and affect, attention, concentration and thought process Based on history, presenting symptoms and diagnostic criteria the case was established as Premenstrual Syndrome. So, the protocol for treatment planned was symptomatic. Internal administration of Gokhura churna plus Yastimadhu with Munnaka kshirapaak was given for 15 days. Rajaswalacharya was advised.


2010 ◽  
Vol 2 (2) ◽  
pp. 123-126
Author(s):  
Deepti Shrivastava ◽  
Bhute Sindhu ◽  
Satarupa Mukherjee

ABSTRACT Polycystic ovarian disease (PCOD) is the most common endocrine disorder in women of reproductive age. The pathogenesis is not completely clear still today. Problems in inducing ovulation in PCOD is well recognized. A retrospective study of last 3 years in patients attending the OPD in the Department of Obstetrics and Gynecology, JNMC, Sawangi, Wardha, who were diagnosed as cases of PCOD with complaints of infertility and irregular menstruatal cycle underwent laparoscopic ovarian drilling. It was concluded that the procedure had higher ovulation and successfull pregnancy rate. It is cost-effective, minimally invasive procedure with lesser hospital stay with less postoperative complications, being ideal for rural setup.


2007 ◽  
Vol 3 (4) ◽  
pp. 395-408 ◽  
Author(s):  
Andrea J Rapkin ◽  
Michelle McDonald ◽  
Sharon A Winer

A combined oral contraceptive pill containing 20 μg of ethinyl estradiol and 3 mg of the progestin drospirenone in a novel dose regimen (24 active pills followed by 4 placebo pills), has demonstrated efficacy for the symptoms of premenstrual dysphoric disorder, a severe form of premenstrual syndrome, with an emphasis on the affective symptoms. Drospirenone has progestagenic, anti-androgenic and anti-aldosterone properties, which differ from earlier generations of progestins, and reducing the hormone pill-free interval allows for better suppression of ovarian steroid production.


2021 ◽  
Vol 7 (2) ◽  
pp. 99-101
Author(s):  
Ambika Nand Jha ◽  
Akshay H Shah ◽  
Upama N Trivedi ◽  
Jignesh S Patel

Streptomycin is a semi-synthetic, oldest aminoglycoside. It is the first line drug for tuberculosis. It may adversely produce ototoxicity, nephrotoxicity, neuromuscular blockage. The initial isolation of streptomycin from Streptomyces griseus. A 51 year old female visited to the medicine OPD in hospital. On presentation she complained of vomiting and vertigo from last few days. The patient recently diagnosed for Pulmonary TB by chest X-ray 3 month back. She taken streptomycin 0.75mg IV bid. As these were the new symptoms, the physician requested for otolaryngologist consultation to rule out the other causes and was insignificant. But the audiometry report showed hearing loss. The ototoxicity caused by aminoglycosides is permanent and can negatively affect the individual’s quality of life. The early detection, management and therapeutic approaches for prevention of hearing loss is crucial. Reporting here is an interesting case of streptomycin induced cochlear toxicity. Bangladesh Journal of Infectious Diseases 2020;7(2):99-101


2020 ◽  
Vol 2 (3) ◽  
pp. 1-5
Author(s):  
Selami Doğan ◽  
Nuray Doğan ◽  
Tevfik Tanju Yılmazer ◽  
Kurtuluş Öngel

Objective: Approximately 80% of women in reproductive age experience some premenstrual ‎phase-related changes in the menstrual cycle. We aimed to determine the prevalence of premenstrual syndrome (PMS) and ‎premenstrual dysphoric disorder symptom frequency among women aged 15-49 years in a family practice catchment area. Material and Methods: A cross-sectional study was conducted in the women registered to a family practice center in İzmir Bayraklı. Out of 522 women at the age of 15-49 years, 198 participants filled the Premenstrual Assessment Form (PAF) and answered demographic questions. The main outcome measures were the presence of “premenstrual ‎symptoms” and “premenstrual syndrome”. Results: The mean age, waist circumference and BMI of the women were 29.3±9.1 years, 80.4±13.2 ‎cm and 25.2±5.1 kg/m2, respectively. Of the participants, 68.2% (n=131) were single and 60.4% ‎‎ (n=116) were housewives. Premenstrual syndrome (PMS) was present in all the women involved in the study. Of ‎these, 3.6% were evaluated as premenstrual dysphoric disorder (PMDD). None of the ‎independent variables in the study revealed as risk factors for PMDD (p>0.05). Mean PAF scores were ‎2.22±0.90‎. There was no correlation between PAF scores and the studied variables except for waist ‎circumference (r = -0.17; p = 0.02). The sociodemographic variables ‎were not related with PMS (p> 0.05).‎ Conclusions: Training and counseling on the causes and ‎symptoms of PMS should be provided to women, particularly in primary health care facilities, and in-service trainings should be ‎conducted to provide information to the staff working in family practice centers.‎


2002 ◽  
Vol 32 (8) ◽  
pp. 452-462 ◽  
Author(s):  
Joseph F Mortola ◽  
David J Brunswick ◽  
Jay D Amsterdam

Author(s):  
Andrea Rapkin ◽  
Mya Zapata

The premenstrual disorders, premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) are psychoneuroendocrine disorders characterized by a constellation of affective, somatic, and behavioural symptoms that occur monthly, during the luteal phase of the menstrual cycle with relief soon after the onset of menses. PMS affects approximately 15–40% of reproductive aged women depending on criteria for diagnosis. PMDD is a severe form of PMS, with an emphasis on the affective symptoms. It has been estimated that only 5–8% of women meet the strict criteria for PMDD, but up to 20% may be one symptom short of meeting the criteria (1). The premenstrual syndromes adversely impact relationships, activities of daily living, and workplace productivity. The research and treatment of the premenstrual disorders have been hampered by lack of consensus regarding the specific diagnostic criteria, methods of assessment of symptoms and impairment, and absence of animal models or biological markers for the disorders. However, elucidation of various aspects of the pathophysiology, well designed multicentre treatment trials, and patient and clinician education have successfully improved diagnosis and management This chapter will review symptoms, definitions, diagnostic criteria, aetiology, evaluation, and nonpharmacological and pharmacological management of PMS and PMDD.


2016 ◽  
pp. 109-112
Author(s):  
Lyudmyla Pakharenko ◽  

The objective: of research is to evaluate course of pregnancy and labor in women with premenstrual syndrome (PMS). Patients and methods. The research included 200 women of reproductive age with diagnosis of PMS and 50 women without diagnosis of PMS. Data of reproductive and obstetrical history were collected. Results. We determined that women with PMS have more pregnancies (in 1.59 times, c2=10.74, p=0.001) and labors (in 1.70 times, c2=10.56, p=0.001) compared with controls. Also they have a tendency for development of pathological course of pregnancy and labor. Complications of pregnancy and labor are the most typical for patients with edematous form of syndrome compared with healthy individuals (c2=4.71, p=0.03, OR=3.92, 95%CI=1.27–12.06, p=0.02). These persons have a greater share of late gestosis – in 4,55 times significantly greater incidences – 47.82% versus 10.52% of women in control group (c2=6.51, p=0.01, OR=7.79, 95%CI=1.61–37.65, p=0.01). Conclusion. Special attention should be paid to women with edematous form of PMS, which are significantly more marked the development of late gestosis. These women are at risk of pathological labor – caesarean section, forceps, hypotonic/atonic postpartum uterine bleeding and preterm labor. Key words: premenstrual syndrome, pregnancy, labor, complications.


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