scholarly journals Effect of Antioxidant Vitamin Complex on Disease Prevention

2019 ◽  
pp. 652-659
Author(s):  
Olga Pozdnyakova ◽  
Maria Kazakova ◽  
Alexander Avstrievskikh ◽  
Valeriy Poznyakovskiy
Keyword(s):  
Quality Of Life ◽  
Health Workers ◽  
Quantitative Description ◽  
Life Quality ◽  
Control Group ◽  
Antioxidant Vitamin ◽  
Social And Emotional ◽  
Sf 36 ◽  
Emotional Aspects

Introduction. Hypovitaminosis is currently common among various social groups. The present research offers a new medical formulation that includes a complex of antioxidant vitamins with a highly beneficial synergistic effect. Study objects and methods. The research employed the SF-36 questionnaire to assess the quality of life in patients with chronic diseases, as recommended by the WHO. The SF-36 questionnaire provides a quantitative description of the physical, emotional, and social components of the quality of life. Clinical control was performed on days 31–32 from the onset of the medication. The state of the microcirculatory bed was assessed in laboratory conditions by applying pressure to the nail bed. The concentration of malondialdehyde was determined by the method developed by M. Uchiyama and M. Mihara. Results and discussion. The paper introduces the formulation and describes the properties of each component. The efficacy of the medicine was confirmed experimentally. Twenty education and health workers were administered the medicine for one month. The control group consisted of fifteen volunteers, who were randomized and grouped according to professional factor, sex, and age. The control group consumed the medicine together with standard vitamins A, C, and E in adequate dosages. Conclusion. The developed medicine proved able to improve the physical, social, and emotional aspects of life quality under high psychophysical stress. The polyvalent effect of the components demonstrated a tropism to collagen synthesis. In addition, it showed an antioxidant effect and improved microcirculation. The medicine can be used preventively to reduce the risk of chronic pathology based on the accumulation of excess free radical activity.

scholarly journals Quality of life in patients with Charcot-Marie-Tooth disease type 1A

2013 ◽  
Vol 71 (6) ◽  
pp. 392-396 ◽  
Author(s):  
Juliana B. Taniguchi ◽  
Valeria M.C. Elui ◽  
Flavia L. Osorio ◽  
Jaime E.C. Hallak ◽  
Jose A.S. Crippa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Control Group ◽  
Life Questionnaire ◽  
Charcot Marie Tooth ◽  
Social And Emotional ◽  
Charcot Marie Tooth Disease ◽  
Sf 36 ◽  
And Gender

We assessed the functional impairment in Charcot-Marie-Tooth resulting from 17p11.2-p12 duplication (CMT1A) patients using the Short-Form Health Survey (SF-36), which is a quality of life questionnaire. Twenty-five patients of both genders aged ≥10 years with a positive molecular diagnosis of CMT1A were selected. Age- and gender-matched Control Group (without family history of neuropathy), and the sociodemographic and professional conditions similar to the patients' group were selected to compare the SF-36 results between them. The results showed that the majority quality of life impairments in CMT1A patients occurred in the social and emotional domains. Functional capacity also tended to be significantly affected; other indicators of physical impairment were preserved. In conclusion, social and emotional aspects are mostly neglected in the assistance provided to CMT1A Brazilian patients, and they should be better understood in order to offer global health assistance with adequate quality of life as a result.

scholarly journals 23 Psycho-emotional aspects in patients with takotsubo syndrome compared with a control group

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Annalisa Matera ◽  
Francesco Santoro ◽  
Adriana Mallardi ◽  
Alessandra Leopizzi ◽  
Enrica Vitale ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Anxiety And Depression ◽  
Control Group ◽  
Social Activities ◽  
Takotsubo Syndrome ◽  
Sf 36 ◽  
Emotional Aspects

Abstract Aims Takotsubo syndrome (TTS), also called stress cardiomyopathy, is an acute and transient left ventricular systolic dysfunction. Patients affected are usually postmenopausal woman with symptoms similar to myocardial infarction (angina pectoris, shortness of breath, palpitations, etc.) who experienced sudden emotional or physical stress. Emotional stressors are the mayor trigger in about 40% of cases, therefore an evaluation of psychological profile of these patients may have clinical relevance. Evaluate the quality of life, the level of anxiety and depression, the activities of daily life in patients with TTS in comparison with a control group with similar characteristics who haven’t developed this pathology. Methods and results 44 patients were recruited: 22 patients with TTS and 22 patients included in the control-group who didn’t develop the syndrome. Patients answered to three questionnaires for the evaluation of daily living activities, (Activities of daily living and Instrumental activities of daily living—ADL and IADL), levels of anxiety and depression (hospital anxiety and depression scale—HADS), and quality of life (36-Item Short Form Health Survey-SF—36). Mean age of the study population was 69 ± 9 years and patients were all female. No differences in term of cardiovascular and no risk factor were found between the two groups. Concerning daily living activities, no differences were present. However, when comparing levels of anxiety and depression, TTS patients had higher levels of anxiety (9.4 ± 5.3 vs. 7.7 ± 4.3; P = 0.3; HADS), meanwhile levels of depression were higher in patients of the control group (6.1 ± 3.4 vs. 6.7 ± 4.7; P = 0.7; HADS). Regarding the quality of life, patients with TTS reported to have reduced energy and had fewer social activities (respectively, 51.2 ± 15.7 vs. 62.8 ± 16.5; P = 0.03; 60.4 ± 29.1 vs. 66.6 ± 30.2 con P = 0.7; SF-36). Conclusions Patients with Takotsubo syndrome have typical psycho-emotional aspects including higher levels of anxiety and impaired quality of life (as reduced energy and fewer social activities). Further research is needed to better stratify these aspects.

scholarly journals Evaluation of life quality in patients with acnes vulgaris

2014 ◽  
Vol 18 (3 (71)) ◽  
Author(s):  
N. O. Voloshyna
Keyword(s):  
Quality Of Life ◽  
Acne Vulgaris ◽  
Severe Disease ◽  
Health Assessment ◽  
Life Quality ◽  
Control Group ◽  
Moderate Degree ◽  
Sf 36 ◽  
The Impact

Abstract. Preliminary few studies indicate that age, gender and duration of acne vulgaris (acne) affect the quality of life of these patients.Objective - to assess the impact of the duration and severity of acne on quality of life of patients in gender, age and professional aspects in connection with the treatment.Material and methods: 98 patients with acne aged 18-29 years, among whom 36 were males (36,73 %), and 62 (63,26 %) females have been examined. The assessment of acne severity classification was carried out according to the classification of the American Academy of Dermatology, while the quality of their life was assessed by means of SF- 36 questionnaire.Results. Mild acne was found in 6 (6,12 %) patients, moderate one in 72 (73,47 %), severe one in 20 (20,41 %) cases. It was established that clinically significant severity of acne was more common in younger male patients (22 years). However, a greater impact on quality of life was found in female patients, older than 22 years, with professions associated with being among a large group of people and in case of long course (more than 4-5 years) of dermatosis. Mild acne had little impact on quality of life.Standard complex acne treatment during two months significantly improved quality of life indicators of patients with moderate degree of acne and most of the indicators in those with severe disease, which, however, didn’t reach the indicators in the people of the control group, and it shows the necessity to improve the programme of treating and preventive measures concerning such patients.Conclusion: Patients with acne have significant changes in life quality, depending on their gender, age and professional peculiarities as well as on the severity of dermatosis course. Determining the indicators of life quality by means of SF-36 questionnaire is an important aspect of the patient’s physical and psychiatric health assessment as well as a reliable criterion of their treatment efficacy.

scholarly journals Life quality of men with ankylosing spondylitis: association with the disease course and the structural and functional state of bone tissue

2021 ◽  
Vol 11 (2) ◽  
pp. 70-78
Author(s):  
S.V. Shevchuk ◽  
O.M. Pavliuk
Keyword(s):  
Quality Of Life ◽  
Ankylosing Spondylitis ◽  
Bone Tissue ◽  
Functional State ◽  
Life Quality ◽  
Control Group ◽  
High Dose ◽  
Mineral Density ◽  
Sf 36

Background. Multiple peculiarities of ankylosing spondylitis clinical course have a significant influence on the phy­sical, mental and social status of patients. Systemic loss of bone tissue manifesting itself through the development of osteoporosis and its complications is not excluded either. However, currently there is no sufficiently clear information on the influence of osteoporosis or its metabolic components, as well as peculiarities of the disease clinical course on the physical and mental health components in the patients suffering from ankylosing spondylitis. Purpose: to study the quality of life indices using the SF-36 and HAQ questionnaires in men suffering from ankylosing spondylitis and to assess the associations of these indexes with the disease cli­nical course as well as structural and functional state of bone tissue. Materials and methods. 105 men suffering from ankylo­sing spondylitis and 25 practically healthy persons of the appropriate age and sex forming the control group were examined. In order to assess the quality of life indices, the SF-36 and HAQ questionnaires were used. Results. It was established that men suffering from ankylo­sing spondylitis showed reliably lower indices of phy­sical (37.3 ± 1.5 points) and mental (44.2 ± 1.7 points) health components if compared to the control group (99.1 ± 0.3; 97.4 ± 0.7 points respectively). Under conditions of the low bone mineral density, quality of life indices (PCS; MCS) were only 12.2–7.1 % lower than in the patients with a preserved bone mineral density. It was shown that under conditions of the Vitamin D deficiency, quality of life components were significantly worse, specifically on account of the mental health component (р < 0.05). It was also established that the lower quality of life was closely associa­ted with a high activity of the inflammatory process (ASDAS-СRP, BASDAI) and a high dose of glucocorticoids. Conclusions. Men suffering from ankylosing spondylitis show a significant reduction of life quality indices by the SF-36 (PCS; MCS) and HAQ questionnaires, which demonstrate no association with the age of the patients (except for MCS), di­sease form and duration, structural and functional state of bone tissue. However, they are significantly worse in subjects with the Vitamin D deficiency, a high dose of glucocorticoids and high disease activity.

scholarly journals Effects of power training on quality of life and postural stability in elderly

2020 ◽  
pp. 1-7
Author(s):  
Grassyara Pinho Tolentino ◽  
Viviane Soares ◽  
Patrícia Espíndola Mota Venâncio ◽  
João Lucas de Moraes ◽  
Pablo Rodrigues Lima ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Short Form ◽  
The Elderly ◽  
Control Group ◽  
Subjective Perception ◽  
Power Training ◽  
Sf 36 ◽  
Emotional Aspects

Introduction: The muscular strength exercises can be an effective intervention to prevent falls and to favor the functional capacity (FC) in the elderly. However, few studies have reported the benefits of power training (PT) and the subjective perception of the elderly on these activities. Objective: to evaluate the repercussions of a power training protocol on functional capacity and subjective health parameters in the elderly. Method: It was a prospective study involving 48 elderly people. Two groups were composed: a power training group (PG) with 22 participants with a mean age of 68.14 (5.46) years and the control group (CG) was composed of 32 elderly individuals aged 68.03 (4.83) years. Health-related quality of life was measured from the Medical Outcomes Study 36 – Item Short-Form Health Survey (SF-36). The FC was measured by the Berg Balance and Time Up and Go tests. The PT was performed 2x/week, with duration of 50 min/session, for 14 weeks (first two weeks of adaptation; first six weeks 3X/10-15 repetitions of 40-50% of the Subjective Perceived Exertion (SPE) / 6 following weeks 3X/6-10 repetitions of 60-70% of the SPE). The CG performed rhythm activities with the same frequency and weekly duration. Result: It was observed favorable results in FC after 14 weeks of power training. There was also a positive evaluation of most sf-36 domains, with emphasis on physical and emotional aspects. However, the perception of the elderly in relation to the pain domain presented negative results. Conclusion: The PT positively influenced the FC, the physical and the emotional aspects of the elderly; negatively affected the pain and maintained the low risk of fall after 12 weeks of intervention, without presenting intercurrences during the intervention.

Quality of life of patients with Sjogren’s disease with ongoing therapy with diseasemodifying antirheumatic drugs

2020 ◽  
pp. 33-38
Author(s):  
E. Yu. Gan ◽  
L. P. Evstigneeva
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Life Quality ◽  
Well Being ◽  
Disease Modifying Antirheumatic Drugs ◽  
Antirheumatic Drugs ◽  
Sf 36 ◽  
Disease Modifying ◽  
Sjögren’S Disease

Purpose of the study. Assessing the association between the life quality of patients with Sjogren’s Disease and ongoing therapy with various disease-modifying antirheumatic drugs.Material and methods. The study was conducted on the basis of the regional rheumatology center of the consultative diagnostic clinic of the Sverdlovsk Regional Clinical Hospital No. 1. This work is based on the results of a simultaneous study of 74 patients with primary Sjogren’s Disease (SD), distributed in three comparison groups receiving various disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine. The diagnosis of SD was carried out according to European-American criteria AECGC (2002) [18]. In order to analyze the quality of life of patients with SD, the 36-Item Short Form Health Survey (SF‑36) was used. Statistical data processing was carried out using Statistica 7.0 program.Results. Assessment of the quality of life of patients with SD, which is an integrative criterion of human health and well-being, revealed the absence of statistically significant differences (p > 0.05) on eight scales and two health components of the SF‑36 questionnaire in the analyzed groups that differ in the treatment of disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine.Conclusions. The obtained data indicate an equivalent quality of life in SD patients treated with different disease-modifying antirheumatic drugs methotrexate, chlorambucil and hydroxychloroquine, and therefore hydroxychloroquine can be considered as an alternative basic therapy in patients with SD with certain limitations and contraindications methotrexate and chlorambucil.

The effects of breathing exercises on respiratory functions, functional capacity and quality of life in vehicle spray painters

2021 ◽  
Vol 28 (12) ◽  
pp. 1-8
Author(s):  
Burak Yilmaz ◽  
Cagtay Maden ◽  
Begümhan Turhan
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Control Group ◽  
Study Group ◽  
Breathing Exercises ◽  
Sf 36 ◽  
Significant Difference ◽  
Before And After ◽  
Respiratory Exercises

Background/aims Workers engaged in vehicle spray painting are at a risk of developing respiratory problems because of the solvents in the spray paints. Changes in respiratory functions and functional capacities caused by spray painting can be improved with respiratory exercises. The aim of this study was to examine the effects of respiratory exercises on the respiratory functions, functional capacity and quality of life in vehicle spray painters. Methods A total of 70 volunteers with similar characteristics participated in the study. The groups were divided into two groups randomly (35 study group, 35 control group). Respiratory functions (value of forced expiratory volume percentage in 1 second [FEV1]), forced vital capacity percentage [FVC], FEV1/FVC percentage, peak expiratory flow percentage [PEF (%)] and maximum voluntary ventilation percentage [MVV (%)]), functional capacity (6-Minute Walk Test) and quality of life (Short Form Health Survey [SF-36]) were evaluated. The study group undertook supervised breathing exercises 3 days a week for 6 weeks. The same exercises were given to the control group as a home programme. Home programmes were followed up by telephone calls. Evaluations were performed again after 6 weeks. Results In the study group, FEV1 (%) increased more than in the control group (P<0.05). The increase in PEF (%) was similar in both groups (P>0.05). In the study group, FEV1/FVC (%) and MVV (%) were significantly different before and after the intervention (P<0.05), but there was no difference in the control group (P>0.05). There was a greater increase in the study group than in the control group (P<0.05). 6-Minute Walk Test distance (m) before and after the intervention in both groups were similar (P>0.05). Before and after the intervention, a significant difference was found in the vitality and the social function domains of the SF-36 in the study group. In the comparisons of groups, a significant difference was found in the study group in the role-emotional, social function and bodily pain domains of the SF-36 after the intervention (P<0.05). Conclusions Breathing exercises can be recommended for vehicle spray painters to avoid an increase in respiratory resistance and to improve their quality of life.

scholarly journals The physical, social and emotional aspects are the most affected in the quality of life of the patients with cervical dystonia

2014 ◽  
Vol 72 (6) ◽  
pp. 405-410 ◽  
Author(s):  
Roberta Weber Werle ◽  
Sibele Yoko Mattozo Takeda ◽  
Marise Bueno Zonta ◽  
Ana Tereza Bittencourt Guimarães ◽  
Hélio Afonso Ghizoni Teive
Keyword(s):  
Quality Of Life ◽  
Cervical Dystonia ◽  
Rating Scale ◽  
Motor Impairment ◽  
Residual Effect ◽  
Spasmodic Torticollis ◽  
Social And Emotional ◽  
Emotional Aspects ◽  
Craniocervical Dystonia

Objective : Describe the functional, clinical and quality of life (QoL) profiles in patients with cervical dystonia (CD) with residual effect or without effect of botulinum toxin (BTX), as well as verify the existence of correlation between the level of motor impairment, pain and QoL. Method : Seventy patients were assessed through the Craniocervical dystonia questionnaire-24 (CDQ-24) and the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS). Results : The greater the disability, pain and severity of dystonia, the worse the QoL (p<0.0001). Greater severity relates to greater disability (p<0.0001). Pain was present in 84% of the sample, being source of disability in 41%. The most frequent complaints were: difficulty in keeping up with professional and personal demands (74.3%), feeling uneasy in public (72.9%), hindered by pain (68.6%), depressed, annoyed or bitter (47.1%), lonely or isolated (32.9%). Conclusion : The physical, social and emotional aspects are the most affected in the QoL of these patients.

scholarly journals Satisfaction with Quality of Life in Patients with Minimum Cicatricial Damage of the Face and Neck

2018 ◽  
Vol 7 (1) ◽  
pp. 75-90 ◽  
Author(s):  
A. Iaremenko ◽  
E. Isaeva ◽  
T. Kolegova ◽  
E. Sitkina ◽  
Yu. Vasilieva
Keyword(s):  
Quality Of Life ◽  
Physical Condition ◽  
Traditional Method ◽  
Comparison Group ◽  
Short Form ◽  
Life Quality ◽  
Control Group ◽  
Surgical Methods ◽  
The Face

Satisfaction with quality of life and self-attitude in patients operated by «traditional» (conventional surgical methods) and endoscopically assisted methods are considered in the article. Differences in the quality of life in patients, self-attitude to ones appearance are described. 65 patients were surgically operated and examined. Control group – patients operated by «traditional» techniques (35 patients), the average age of patients was 38 ± 11,1 years. The comparison group – patients operated using endoscopically assisted methods (30 patients), the average age of patients was 44 ± 17,7 years. Psychodiagnostic methods: 1. N. E. Vodopyanova`s scale of life quality; 2. The Short Form-36; 3. S.R. Panteleev`s Assessment of self-relationship. Complaints of paresthesia and pain experienced by patients who underwent a “traditional” operation were revealed as a result of the examination. Operated on with an endoscopically assisted method patients did not present any complaints. Differences between the assessment of the life quality and self-relationship in examined groups were found. Operated on with an endoscopically assisted method patients evaluated life quality, satisfaction with their appearance and physical condition higher than patients operated on with a “traditional” method.

scholarly journals Quality of Life of Patients with Stable Coronary Artery Disease Combined with Non-Alcoholic Fatty Liver Disease

2016 ◽  
Vol 23 (4) ◽  
pp. 2016416
Author(s):  
Iryna Vakalyuk ◽  
Nataliya Virstyuk ◽  
Vitaliy Petryna
Keyword(s):  
Quality Of Life ◽  
Liver Disease ◽  
Stable Coronary Artery Disease ◽  
Control Group ◽  
Alcoholic Fatty Liver ◽  
Group I ◽  
Sf 36 ◽  
Artery Disease ◽  
Alcoholic Fatty Liver Disease

Quality of life assessment is an integral part of a comprehensive treatment in modern medical practice. Analysis of quality of life of patients with comorbidities is an interesting and poorly understood issue. The objective of the research was to evaluate the quality of life of patients with postinfarction cardiosclerosis depending on the presence and progression of non-alcoholic fatty liver disease (NAFLD).Material and methods. The research included 300 patients with stable coronary artery disease (CAD). They included 160 patients without NAFLD (Group I) and 140 patients with NAFLD (Group II). 89 patients of Group II suffered from non-alcoholic liver disease (NALD) and 51 patients from non-alcoholic steatohepatitis (NASH). The control group consisted of 20 apparently healthy individuals. SF-36 and MacNew questionnaires were used to assess the quality of life. Results. The overall estimate according to SF-36 questionnaire detected a significant decrease in the patient’s quality of life due to their low physical activity, mental ill-being, limitation of daily activities, significant effect of pain and low assessment of their health. Decrease in the quality of life was clearly dependent on NAFLD stage and was the lowest in case of NASH. The overall estimate of quality of life according to MacNew questionnaire was 1.5 times lower in patients of Group I compared to the control group, decreased almost by 1.4 times in patients with NALD compared to Group I and was 1.5 times lower in case of NASH compared to the patients with NALD (p<0.05). Conclusions. Patients with stable CAD combined with NAFLD were characterized by decrease in quality of life due to its physical, psycho-emotional and social components. Quality of life of patients with postinfarction cardiosclerosis depended on NAFLD progression and was the lowest in case of NASH.

Sign in / Sign up

Export Citation Format

Share Document