scholarly journals Correlation between Urinary Bisphenol A, Serum 25 OH Vitamin D Levels and Preterm Birth in Egyptian Pregnant Women

2021 ◽  
Vol 9 (1) ◽  
pp. 21-33
Author(s):  
Sahar El-Dakroory ◽  
Reem Abo-Elmaaty ◽  
Sara Mohamed ◽  
Adel El-Mansory ◽  
Nermin Emam
Keyword(s):  
Vitamin D ◽  
Preterm Birth ◽  
Bisphenol A ◽  
Pregnant Women ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

The role of Vitamin D in the prevention of pregnancy complications and childhood diseases in the first year of life

2021 ◽  
Vol 20 (5) ◽  
pp. 114-123
Author(s):  
E.V. Shikh ◽  
◽  
A.A. Makhova ◽  
Zh.M. Sizova ◽  
N.V. Shikh ◽  
...  
Keyword(s):  
Vitamin D ◽  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Pregnancy Complications ◽  
Vitamin D Supplementation ◽  
Childhood Diseases ◽  
Vitamin D Levels ◽  
First Year Of Life

Vitamin D status during pregnancy has an impact on fetal growth and development and plays an important role in the prevention of pregnancy complications. Fetal vitamin D supplementation is completely dependent on maternal status, which explains the high correlation between 25(OH)D concentrations in maternal and umbilical cord blood. Adequate vitamin D supplementation in pregnant women is associated with a decreased risk of preterm birth and low birth weight. Most newborns, regardless of gestational age, have insufficient vitamin D levels. Thus, the problem of Vitamin D supplementation is relevant not only for pregnant women, but also for newborns. Research studies of recent years have aimed at comparing the efficacy of Vitamin D dosing to prevent pregnancy complications. Doses higher than 4000 IU have virtually no effect on the risk of preeclampsia compared with doses of 4000 IU or less. Administration of Vitamin D in doses less than 2000 IU per day reduces the risk of low birth weight, intrauterine or neonatal mortality. Doses higher than 2000 IU have no additional benefit. Recommendations for vitamin D supplementation based on objective pharmacokinetic characteristics should be developed. Key words: pregnancy, vitamin D, doses, preterm birth, gestational diabetes, preeclampsia

The correlation between vitamin D and maternal/infant outcomes, inflammatory response in pregnant women

2020 ◽  
Author(s):  
Yarong Wei ◽  
Xinye Jiang ◽  
Ting Qiu ◽  
Jinyan Fu ◽  
Heng Zhang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Preterm Birth ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Spontaneous Abortion ◽  
Gestational Age ◽  
Serum Vitamin ◽  
Multivariate Logistic Regression Analysis ◽  
Premature Delivery ◽  
Vitamin D Levels

Abstract Purposes To analyze the effects of vitamin D deficiency in pregnant women on common adverse pregnancy outcomes and small for gestational age (SGA) and to detect the expression of inflammatory factors in pregnant women to provide a theoretical basis for the treatment of vitamin D deficiency in pregnant women. Methods Serum samples from pregnant women from January 2015 to December 2015 were collected to measure the 25-(OH)D level. The effects of maternal age, pregnancy, season, parity and temperature on vitamin D levels in pregnant women were recorded. Then, the relationship between vitamin D levels and gestational diabetes mellitus, gestational hypertension, premature rupture of membranes, cesarean section, premature delivery and spontaneous abortion, and neonatal gestational age were analyzed. The expression of IL-6 and TNF-α in serum was detected by RT-PCR and western blot. Results The incidence of vitamin D deficiency, insufficiency and sufficiency in pregnant women in this region was 83.28%, 15.36% and 1.36%, respectively. Age, pregnancy, sampling season and parity were the influencing factors on vitamin D level, and multivariate logistic regression analysis showed that summer, autumn and temperature were protective factors for adequate vitamin D in pregnant women (P <0.05). Vitamin D levels in pregnant women were associated with preterm birth, spontaneous abortion and SGA. The incidences of preterm birth, spontaneous abortion and SGA were higher in the vitamin D deficiency group (P<0.05). ConclusionThe serum vitamin D level of pregnant women in this area is low and is affected by multiple factors such as age, pregnancy, season, parity and temperature. Low vitamin D levels can increase the risk of premature birth, spontaneous abortion and SGA in pregnant women, and its low expression is common. As it also leads to inflammation, increasing the level of vitamin D in the serum of pregnant women can effectively reduce the occurrence of related diseases.

scholarly journals The relationship between 25(OH) vitamin D levels and COVID-19 onset and disease course in Spanish patients

2021 ◽  
pp. 105928
Author(s):  
Manuel Diaz-Curiel ◽  
Alfonso Cabello ◽  
Rosa Arboiro-Pinel ◽  
Luis Mansur ◽  
Sarah Heili-Frades ◽  
...  
Keyword(s):  
Vitamin D ◽  
Disease Course ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D ◽  
The Relationship

Decline in serum 25-OH vitamin D levels in HIV/hepatitis B virus (HBV) co-infected patients after long term antiretroviral therapy

2013 ◽  
Vol 19 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Anchalee Avihingsanon ◽  
◽  
Tanakorn Apornpong ◽  
Reshmie A Ramautarsing ◽  
Sasiwimol Ubolyam ◽  
...  
Keyword(s):  
Vitamin D ◽  
Hepatitis B Virus ◽  
Antiretroviral Therapy ◽  
Hepatitis B ◽  
Vitamin D Levels ◽  
B Virus ◽  
25 Oh Vitamin D

Low Dose Depot Oral Vitamin D3 Versus Daily Oral Vitamin D3 for Treating Nutritional Rickets: A Randomized Clinical Trial

2021 ◽  
pp. 1-18
Author(s):  
Ravneet Kaur Saluja ◽  
Pooja Dewan ◽  
Sunil Gomber ◽  
SV Madhu ◽  
Shuchi Bhatt ◽  
...  
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Vitamin D3 ◽  
Low Dose ◽  
Care Hospital ◽  
Oral Vitamin ◽  
Nutritional Rickets ◽  
Vitamin D Levels ◽  
Radiological Healing ◽  
25 Oh Vitamin D

Abstract Objective: To compare the efficacy of daily versus low dose depot oral vitamin D3 for treating nutritional rickets. Design: Randomized Controlled Trial Setting: Paediatrics department of a tertiary care hospital catering to semi-urban and rural population in Delhi, India Methods: We randomized 66 children aged 3 months to 5 years with nutritional rickets to receive either daily oral vitamin D3 drops (3-12 months: 2000 IU; >12 months-5y: 4000 IU; n=33) for 12 weeks duration, or a single oral depot dose of vitamin D3 granules (3-12 months: 60,000 IU; >12 months-5y: 150,000 IU; n=33). Results: Participants in both groups had comparable demographic characteristics, laboratory features and radiological severity of rickets. 33 participants in each group received the assigned intervention and all were followed up till 12 weeks. At 12 weeks follow up, children in both groups showed a significant improvement in all biochemical parameters [serum calcium, phosphorus, alkaline phosphatase, parathormone and 25(OH) vitamin D levels] as well as radiological healing. At 12 weeks, the mean (SD) serum 25(OH) vitamin D levels (nmol/L) were statistically comparable in both groups [daily: 120.2 (83.2), depot: 108 (74), P=0.43] and 31 (94%) children in each group had radiological healing (Thacher score <1.5). Two children in each group persisted to have raised alkaline phosphatase and one child each in the daily group continued to have hypocalcemia and hypophosphatemia at 12 weeks. Conclusion: Low dose oral depot vitamin D3 is an effective alternative to daily oral vitamin D3 for nutritional rickets.

scholarly journals No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South

2017 ◽  
Vol 75 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Yara Dadalti Fragoso ◽  
Tarso Adoni ◽  
Soniza Vieira Alves-Leon ◽  
Samira L. Apostolos-Pereira ◽  
Walter Oleschko Arruda ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Large Population ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Serum Vitamin D ◽  
Control Subjects ◽  
Vitamin D Levels ◽  
The Mean ◽  
25 Oh Vitamin D

ABSTRACT Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The mean serum 25-OH vitamin D level was 26.07 ± 10.27 ng/mL for the control subjects, and 28.03 ± 12.19 ng/mL for patients with MS. No correlation was observed between vitamin D levels and the disability of patients over the disease duration. Conclusion: At least for the region around the Tropic of Capricorn, serum levels of vitamin D typically are within the range of 20 to 30 ng/mL for controls and patients with MS.

Validation of a locally derived serum calcium adjustment equation: relationship with total 25(OH) vitamin D and PTH levels

2016 ◽  
Vol 70 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Jonathan Joseph Scargill ◽  
John Mark Guy
Keyword(s):  
Vitamin D ◽  
Fold Increase ◽  
Reference Interval ◽  
Albumin Concentration ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
25 Oh Vitamin D ◽  
New Equation ◽  
The Uk ◽  
Adjustment Equation

AimsMany clinical laboratories in the UK use a standard equation to adjust total calcium for albumin concentration. To assess the validity of this practice, we assessed the effect of the use of a traditional and locally derived calcium adjustment equation on parathyroid hormone (PTH) and 25(OH, hydroxy) vitamin D levels.MethodsSamples requested for calcium and albumin measurement over a 6 month period that met inclusion criteria were used to derive a calcium adjustment equation (n=60 941). The traditional and locally derived calcium adjustment equations were then applied to a second cohort of adult patients that underwent calcium measurement over a 1 year period (n=275 456). Patients were classified as hypocalcaemic, normocalcaemic or hypercalcaemic using a UK Pathology Harmony adjusted calcium reference interval (2.2–2.6 mmol/L).ResultsThe local calcium adjustment equation provided a 7.1-fold reduction in the prevalence of hypocalcaemia. Patients classified as hypocalcaemic using the locally derived equation had statistically significantly lower 25(OH) vitamin D and higher PTH levels. A 2.4-fold increase in the prevalence of hypercalcaemia was also observed using the new equation, but with no significant difference in 25(OH) vitamin D or PTH levels.ConclusionsA locally derived calcium adjustment equation reclassified the calcium status of 61 278 (22%) patients. Patients classified as hypocalcaemic by the locally derived equation had significantly lower 25(OH) vitamin D and significantly higher PTH values, providing evidence that use of this adjustment equation generates adjusted calcium results of greater clinical relevance. This study provides further and novel evidence that individual laboratories should determine local equations for adjusted calcium where possible.

Abstract 121: Vitamin D Deficiency Study in Postural Orthostatic Tachycardia Syndrome

2015 ◽  
Vol 8 (suppl_2) ◽  
Author(s):  
Chandralekha Ashangari ◽  
Amer Suleman
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Electronic Medical Records ◽  
Vitamin D3 ◽  
Medical Records ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Vitamin D Levels ◽  
The World ◽  
25 Oh Vitamin D ◽  
Vitamin D3 Deficiency

Objectives The aim of this study is to assess vitamin D levels, including the prevalence of vitamin D deficiency/insufficiency in Postural Orthostatic Tachycardia Syndrome (POTS) patients. Background : The Postural Orthostatic Tachycardia Syndrome (POTS) affects primarily young women. POTS is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. We frequently find vitamin D deficiency in patients who present with POTS Methods: 180 patients were selected randomly from our clinic with POTS. Patients Vitamin D levels charts were reviewed from electronic medical records, 25-OH vitamin D (Vitamin D3 ) status was defined as Normal (>30 ng/mL), Insufficient (20.0-29.9 ng/mL), and deficient (<20 ng/mL). Results: Out of 180 patients, 170 patients are female (94%, n=170, age 31.88±10.36), 10 patients are male (6% ,age 25.83±6.19). 79 patients had vitamin D3 level >30 ng/ml, 10 patients had vitamin D3 level range >20.0 to 29.9 ng/mL, 91 patients had vitamin D3 level < 20ng/mL. Conclusion: Our research results demonstrated that Postural Orthostatic Tachycardia Syndrome (POTS) patients have a higher rate of vitamin D3 deficiency (51% have Vitamin D3 less than 20 ng/mL). Vitamin D3 levels are low in more than half of POTS patients (56% had less than 30 ng/mL )

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