scholarly journals BIOCHEMICAL STUDIES ON THE ANTIMICROBIAL EFFECT OF SOME MEDICINAL PLANTS

2021 ◽  
Vol 6 (3) ◽  
pp. 41-42
Author(s):  
A. A. Saqr ◽  
Kh. M. Taha ◽  
M. M. Abozid
Keyword(s):  
Medicinal Plants ◽  
Antimicrobial Effect ◽  
Biochemical Studies

In vitro antimicrobial and preliminary phytochemical screening of some Samburu Anti‐diarrhoeal medicinal plants ‐ Kenya

2012 ◽  
Vol 2 (5) ◽  
pp. 217-226
Author(s):  
E. O. Omwenga ◽  
P. O. Okemo ◽  
P. K. Mbugua
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Fungal Pathogens ◽  
Antimicrobial Effect ◽  
Significant Activity ◽  
Bacterial Strains ◽  
Fungal Strains ◽  
Local Isolate ◽  
Agar Disc

The antimicrobial effect of some selected Samburu medicinal plants was evaluated on bacterial strains like Staphylococcus aureus ‐ ATCC 20591, Bacillus subtillis ‐ Local isolate, Salmonella typhi‐ATCC 2202, Escherichia coli‐STD. 25922 and Pseudomonas aeroginosa ‐ ATCC 25852 and fungal strains like Candida albicans ATCC EK138, Aspergillus niger ATCC 16404, Aspergillusflavus‐Local isolate, Fusarium lateritium‐Local isolate, and Penicillium spp.‐ local isolate. Methanol was used as solvent for the extraction from the selected medicinal plants used by the Samburu community. The in vitro antimicrobial activity was performed by agar disc diffusion and micro‐dilution technique. The most susceptible Gram‐positive bacterium was S. aureus, while the most susceptible Gram‐negative bacterium was P. aeroginosa. The extracts of Gomphocarpus fruticosus (L) W.T. Aiton showed less activity against the bacterial strains investigated. The most active antibacterial plants were Euphorbia scarlatica S. Carter, and Euclea divinoram Hiern. Incidentally most of the extracts were inactive against the fungal strains with only a few proving to be slightly active against the C. albicans i.e. Loranthus acaciae Zucc., Kedrostis pseudogijef (Gilg) C. Jeffrey, Euclea divinoram Hiern. and Croton macrostachyus (A. Rich). Benths. The significant antimicrobial activity of active extracts was compared with the standard antimicrobials, cefrodoxima, amoxicillin and fluconazole. The MICs of the most active plants ranged from 18.75mg/ml to 37.50mg/ml. The MBCs ranged between 18.75mg/ml to75mg/ml. These results were significant at P< 0.01. The findings show that most of the medicinal plants used by the Samburu community have some significant activity on the bacterial but not fungal pathogens known to cause diarrhoea.

scholarly journals Evaluation of antimicrobial activity of three important medicinal plants of South India

2019 ◽  
Vol 8 (1) ◽  
pp. 3484
Author(s):  
Gopalakrishnaiah B. ◽  
Aniel Kumar O.
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Development Program ◽  
Antimicrobial Effect ◽  
Trichophyton Mentagrophytes ◽  
Crude Extracts ◽  
The World

India is found to be a country with rich biodiversity and enormous treasure of herbal plants and consequently called as medicinal garden of the world. Plants are the richest source of natural antimicrobial agents. In recent years drug resistance to human pathogenic bacteria has been commonly reported from all over the world. Therefore, there is a need to develop alternative antimicrobial drugs for the treatment of infectious diseases; one approach is to screen local medicinal plants for possible antimicrobial properties. The present study was designed to evaluate the antimicrobial efficacy of hexane, chloroform and methanol crude extracts of the leaves of three important medicinal plants viz., Biophytum sensitivum (L.) DC, Bougainvillea spectabilis L. and Caesalpinia bonducella (L.) Fleming, collected from in and around Visakhapatnam District. The antimicrobial activity of the crude extracts was tested against three Gram Positive bacteria (Bacillus subtilis MTCC 441, Enterococcus faecalis MTCC 439, Staphylococcus aureus MTCC 737), Three Gram Negative bacteria (Escherichia coli MTCC 443, Proteus vulgaris MTCC 426 and Pseudomonas aeruginosa MTCC 1688) and three Fungal strains (Candida albicans MTCC 227, Epidermophyton floccosum MTCC 613 and Trichophyton mentagrophytes MTCC 7687) using agar well diffusion assay. Our results demonstrated that methanol extracts of these plants leaves have concentration dependent antibacterial activity against some of the tested organisms. Further studies should be undertaken to elucidate the exact mechanism of action of antimicrobial effect to identify the active ingredients which can be used for drug development program.

scholarly journals BIOCHEMICAL STUDIES ON SOME MEDICINAL PLANTS

2020 ◽  
Vol 5 (1) ◽  
pp. 37-38
Author(s):  
M. A. Habib ◽  
A. M. Farid ◽  
Hoda E. A. Farid
Keyword(s):  
Medicinal Plants ◽  
Biochemical Studies

scholarly journals Pharmaceutical and nutraceutics on three endemic species of Ceropegia

2018 ◽  
Vol 7 (5) ◽  
pp. 2221
Author(s):  
Binish T. ◽  
Pushpa R.
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Nutritive Value ◽  
Total Proteins ◽  
Nutritional Values ◽  
Plant Parts ◽  
Three Samples ◽  
Biochemical Studies ◽  
Total Carbohydrates

Plants are the richest resource of drugs of traditional systems of medicine and modern medicines. Medicinal plant species has its own nutrient composition besides pharmacologically important phytochemicals. Nutraceutics is an emerging field of therapy. As we come to the end of this millennium, more and more people are getting health conscious are looking at dietary substances for preventive or curative effects. The importance of minerals such as potassium, calcium, sodium etc. to human health is well known.The nutritional values and mineral composition of medicinal plants are being used as dietary supplements by humans. The nutritional compositions of selected Ceropegia species were found as good nutritive value. Nutritive compositions were analyzed and compared in vitro plant parts of Ceropegia spiralis, Ceropegia candelabrum and Ceropegia juncea. Sixty to seventy five days old in vitro plants were taken for biochemical studies of total proteins, total carbohydrates, sugar, starch and amino acid.Among the three samples analyzed, high protein sugar and aminoacids content was noticed in Ceropegia  juncea and total carbohydrates and protein values high in Ceropegia candelabrum, Ceropegia candelabrum was found to be a rich source of iron (18.55±0.11) followed by Ceropegia juncea (17.74±0.25) and Ceropegia spiralis (17.56±0.25).Nutraceuticals importance of these valuable plants may help in future for the production of new medicines and valuable food stuffs.  The secondary metabolitices present in them give them a specific medicinal benefit other than a purely nutritional.These species are utilized for Indian system of medicine and scientists encourage them to rationalize it suiting the modern requirements of biotechnology.

scholarly journals Antimicrobial Effect of Non-polar Compounds Extracted from Medicinal Plants

2020 ◽  
Vol 8 (3) ◽  
pp. 61-68
Author(s):  
Sana Ghazanfar ◽  
Muhammad Shahid ◽  
Huadong Liu ◽  
Muhammad Shafa
Keyword(s):  
Medicinal Plants ◽  
Antimicrobial Effect ◽  
Polar Compounds

scholarly journals In Vitro comparison in the antimicrobial effect between Ciprofloxacin and Neem leaf extract (Azadirachta indica) on Escherichia coli Growth

2016 ◽  
Vol 15 (2) ◽  
pp. 172-177
Author(s):  
Quazi Rubyath Banna ◽  
Badar Uddin Umar ◽  
S M Niazur Rahman ◽  
Tanbira Alam ◽  
Kazi Selim Anwar ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Medicinal Plants ◽  
Medical Science ◽  
Antibiotic Sensitivity ◽  
Antimicrobial Effect ◽  
Zone Of Inhibition ◽  
E Coli ◽  
Neem Leaves ◽  
Wide Range

Objective: Medicinal plants remain in vogue to treat some diseases in lower socio-economic communities, despite the availability of antimicrobials, often. Majority of rural Bangladeshi and tribal people being grossly illiterate and ignorant, use various herbs to treat a wide range of diseases. Of several medicinal-plants, neem is reported to have enormous impact in treating inflammation and infections. We, therefore, compared the antimicrobial effect of ethanolic neem leave extract (ENLE) on Escherichia coli (E. coli), with that of Ciprofloxacin. Materials & Methods: This experimental study compared the in vitro antimicrobial activity between ENLE and Ciprofloxacin on E. coli carried out in Department of Pharmacology and Therapeutics of SS-Medical College, Dhaka, Bangladesh. Antimicrobial efficacy of ENLE and ciprofloxacin (5µg; Oxoid, UK) was determined against E. coli following minimum inhibitory concentration. By filtration and evaporation of Neem leaves ENLE was prepared. Antibiotic Sensitivity Test was performed on Muller-Hinton agar using a twofold serial dilution. Results: ENLE showed an inhibitory effect on the growth of E. coli at the concentration of 3.125 mg/ml. Antibacterial susceptibility of E. coli was performed on MHA and diameters of zone of inhibition by both ENLE and Ciprofloxacin were measured after overnight aerobic incubation at 37°C. Diameter of zone of inhibition against E. coli was 28 ± 0.16 mm with ENLE, 36 ± 0.07 mm with Ciprofloxacin (5µg/disk) (p<0.000). Conclusion: Findings of this preliminary in-vitro experiment though suggests that, ENLE against E. coli showed limited efficacy, better efficacy of Ciprofloxacin cannot be ruled out unless further in depth studies elucidates stronger evidences to support it.Bangladesh Journal of Medical Science Vol.15(2) 2016 p.172-177

Biochemical Studies on the Essential Oils of some Medicinal Plants

1986 ◽  
Vol 88 (2) ◽  
pp. 69-72 ◽  
Author(s):  
R. S. Farag ◽  
H. Salem ◽  
A. Z. M. A. Badei ◽  
D. E. Hassanein
Keyword(s):  
Medicinal Plants ◽  
Essential Oils ◽  
Biochemical Studies

scholarly journals Antimicrobial activity of medicinal plants used for urinary tract infections in pastoralist community in Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Eshetu Gadisa ◽  
Elazar Tadesse
Keyword(s):  
Antimicrobial Activity ◽  
Urinary Tract ◽  
Medicinal Plants ◽  
Urinary Tract Infections ◽  
Antimicrobial Effect ◽  
Inhibition Zone ◽  
Resistant Bacteria ◽  
Chemical Structures ◽  
Tract Infections

Abstract Background Medicinal plants have wide medicament application used to prevent and management of many ailments. These plants are used for primary health care in pastoralist communities who are deprived of modern medical care. They possess extensive therapeutics bioactive coupled with varied chemical structures. However, scientific validation of efficacy and safety of plants used to treat the urinary tract infections haven’t been fully exploited. The aim of this study was to evaluate antimicrobial activity and screening phytochemicals of medicinal plants used to treat urinary tract infections. Methods In-vitro experimental study was carried out to evaluate the antimicrobial effect and screening phytochemical of Rumex abyssinicus, Cucumis pustulatus, Discopodium penninervium, Lippia adoensis, Euphorbia depauperata, and Cirsium englerianum. Against drug resistance microbes. 80% methanol was used for extraction of the plant parts. The susceptibility tests were investigated using disc diffusion and broth micro-dilution methods. Results The majority of tested extracts showed antimicrobial activity on two or more drug-resistant bacteria with MIC value (1.0–128.0 μg/ml) and 9–27 mm inhibition zone in diameter. Extracts obtained from C.englerianum and E. depauperate showed more potent antibacterial activity on MRSA and Enterococcus faecalis with IZ 25 and 27 mm respectively. E. coli and K. pneumoniae were inhibited by those extracts with IZ ranging 9–25 mm and 11–27 mm respectively. E.faecalis and K. pneumoniae were more susceptible bacteria to the respective extracts. R. abyssinicus showed promising antifungal effect with had 21 mm IZ and MIC range 16-32 μg/ml on C.albicans. Alkaloids, flavonoids, phenolic and terpenoid were common phytochemical characterized in majority of screened plants. Conclusion Tested extracts exhibited significant antibacterial and antifungal activity. Hence, further structural elucidation of bioactive that inhibited the growth of microbes aforementioned plants may be used as precursors for the synthesis of new antibiotics in the future.

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