scholarly journals Endothelin-1 as a risk factor causing cardiovascular pathology in young and middle-aged people employed under hazardous working conditions

2021 ◽  
pp. 105-113
Author(s):  
I.A. Umnyagina ◽  
◽  
T.V. Blinova ◽  
L.A. Strakhova ◽  
V.V. Troshin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Risk Factor ◽  
Blood Serum ◽  
Body Mass ◽  
Working Conditions ◽  
Middle Aged ◽  
Cardiovascular Pathology ◽  
Endothelin 1 ◽  
Aged People

Our research goal was to reveal peculiarities related to changes in endothelin-1 contents in blood serum in young and middle-aged people exposed to occupational noise and industrial welding and silicon-containing aerosols with fibrogenic effects. Another goal was to establish a correlation between endothelin-1 contents and blood pressure, body mass, and dyslipidemia. We examined workers employed at a metallurgic plant in Nizhniy Novgorod region. Endothelin-1 concentration in blood serum was determined with «Endothelin (1-21)», a reagent kit for ELISA produced by «Biomedica Medizinprodukte GmbH & Co KG» (Austria). We detected certain group differences in endothelin-1 contents in blood serum and frequency of its elevated concentrations between workers who had to work under different working conditions. We established a direct correlation between endothelin-1 and blood pressure, total cholesterol, and body mass index. Elevated endothelin-1 contents in people suffering from arterial hypertension can indicate a higher risk of complications this disease might have. People who have elevated endothelin-1 contents but normal blood pressure, total cholesterol within physiological standard and normal body mass index can be recommended to have regular medical check-ups focusing on functional state of their cardiovascular system; endothelin-1 in this case should be considered a risk factor that might cause cardiovascular pathology occurrence. An individual approach is required when assessing elevated endothelin-1 contents and probable use of this parameter as a risk factor that might cause cardiovascular pathology in young and middle-aged people employed under hazardous working conditions.

scholarly journals Endothelin-1 as a risk factor causing cardiovascular pathology in young and middle-aged people employed under hazardous working conditions

2021 ◽  
pp. 105-113
Author(s):  
I.A. Umnyagina ◽  
◽  
T.V. Blinova ◽  
L.A. Strakhova ◽  
V.V. Troshin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Risk Factor ◽  
Blood Serum ◽  
Body Mass ◽  
Working Conditions ◽  
Middle Aged ◽  
Cardiovascular Pathology ◽  
Endothelin 1 ◽  
Aged People

Our research goal was to reveal peculiarities related to changes in endothelin-1 contents in blood serum in young and middle-aged people exposed to occupational noise and industrial welding and silicon-containing aerosols with fibrogenic effects. Another goal was to establish a correlation between endothelin-1 contents and blood pressure, body mass, and dyslipidemia. We examined workers employed at a metallurgic plant in Nizhniy Novgorod region. Endothelin-1 concentration in blood serum was determined with «Endothelin (1-21)», a reagent kit for ELISA produced by «Biomedica Medizinprodukte GmbH & Co KG» (Austria). We detected certain group differences in endothelin-1 contents in blood serum and frequency of its elevated concentrations between workers who had to work under different working conditions. We established a direct correlation between endothelin-1 and blood pressure, total cholesterol, and body mass index. Elevated endothelin-1 contents in people suffering from arterial hypertension can indicate a higher risk of complications this disease might have. People who have elevated endothelin-1 contents but normal blood pressure, total cholesterol within physiological standard and normal body mass index can be recommended to have regular medical check-ups focusing on functional state of their cardiovascular system; endothelin-1 in this case should be considered a risk factor that might cause cardiovascular pathology occurrence. An individual approach is required when assessing elevated endothelin-1 contents and probable use of this parameter as a risk factor that might cause cardiovascular pathology in young and middle-aged people employed under hazardous working conditions.

scholarly journals Relationship of Occupation to Blood Pressure Among Middle-Aged Japanese Men-The Significance of The Differences in Body Mass Index and Alcohol Consumption -

1998 ◽  
Vol 8 (4) ◽  
pp. 216-226 ◽  
Author(s):  
Yutaka Takashima ◽  
Asao Yoshida ◽  
Katsuki Kokaze ◽  
Ysuhide Orido ◽  
Shoichiro Tsugane ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Alcohol Consumption ◽  
Body Mass ◽  
Middle Aged ◽  
Japanese Men ◽  
Relationship Of

scholarly journals Relation of blood pressure and body mass index during childhood to cardiovascular risk factor levels in young adults

2009 ◽  
Vol 27 (9) ◽  
pp. 1766-1774 ◽  
Author(s):  
Erin R Rademacher ◽  
David R Jacobs ◽  
Antoinette Moran ◽  
Julia Steinberger ◽  
Ronald J Prineas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Young Adults ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Body Mass ◽  
Cardiovascular Risk Factor

scholarly journals Sex Differences in the Influence of Sleep on Body Mass Index and Risk of Metabolic Syndrome in Middle-Aged Adults

Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 561
Author(s):  
Hyun-E Yeom ◽  
Jungmin Lee
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Middle Aged ◽  
Cross Sectional ◽  
Aged People ◽  
Middle Aged Adults ◽  
The Impact

Poor sleep and obesity are intimately related to cardiovascular diseases. We aimed to examine whether the influence of sleep and body mass index (BMI) on the risk of metabolic syndrome (MetS) differed by sex in middle-aged people. It is a cross-sectional study of 458 Korean participants who completed self-administered surveys; the data were analyzed using the PROCESS macro for SPSS. We found that both sleep and BMI were significant predictors of MetS risk in women, particularly by the role of BMI connecting the impact of sleep to MetS risk. However, the association was not found in men, showing that BMI, but not sleep, was a significant predictor of MetS. This sex-related difference was due to different relationships between sleep and BMI, indicating that BMI was more dependent on sleep quality for women than for men. Therefore, a sex-specific approach to decrease the risk of MetS is warranted.

scholarly journals Effects of Short-term Variation in Body Mass Index on Blood Pressure in Middle-aged Japanese Male Workers

2009 ◽  
Vol 55 (1) ◽  
pp. 62-71 ◽  
Author(s):  
Takaaki Kondo ◽  
Akiko Kimata ◽  
Kanami Yamamoto ◽  
Sayoko Ueyama ◽  
Jun Ueyama ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Middle Aged ◽  
Short Term ◽  
Japanese Male ◽  
Term Variation ◽  
Male Workers

scholarly journals Associations of blood glucose levels with some diabetes risk factors (body mass index, blood pressure and total body fat) in inhabitants of Ho Municipality, Ghana: A cross-sectional survey

2021 ◽  
Vol 21` (01) ◽  
pp. 17365-17378
Author(s):  
Nii Korley Kortei ◽  
◽  
A Koryo-Dabrah ◽  
SK Angmorterh ◽  
D Adedia ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Risk Factor ◽  
Blood Glucose ◽  
Correlation Analysis ◽  
Body Mass ◽  
Body Fat ◽  
Lifestyle Modification ◽  
Total Body Fat ◽  
Total Body

One complex metabolic disorder that can unenviably affect the normal human physiology is diabetes mellitus(DM). It is indeed one of the commonest non-communicable diseases that has heightened to an epidemic level worldwide. For diseases like DM, hypertension, cardiovascular disease, type II DM, and other chronic diseases, body mass index (BMI) is identified as a positive and independent risk factor associated with morbidity and mortality. The objective of the study was to determine the relationships between BMI,blood pressure, and total body fat among inhabitants of peri-urban Ho, Ghana. Across-sectional survey was carried out between May and June,2018,among 132 inhabitants of Ho to determine the prevalence and associations among DM risk factors.The participants were selected by systematic random sampling. Standardized international protocols were used to measure BMI, blood pressure, blood glucose, and total body fat. Out of 132 respondents, majority 96 (72.7%) were female and the most common age group was 54-60 (31.1%). From the BMI classifications, 65 (49.2%) people were of normal weight while 6 (4.5%) were underweight. Total body fat (%) and blood pressure, likewise total body fat and BMI recorded significant associations of values (0.299, p<0.001-systolic; 0.298, p=0.001-diastolic), and 0.585(p<0.001),respectively. On the contrary, there were insignificant associations found between blood glucose and diastolic blood pressure and also blood glucose and systolic blood pressure(0.100, p=0.253)and (0.057. p=0.514),respectively using the Spearman’s correlation analysis. Lastly,the test of association of socio-demographics and anthropometrics revealed there was a significant (p<0.001)correlation between total body fat and BMI using Pearson’s correlation analysis. BMI is closely related to total body fat and blood pressure;hence,education on lifestyle modification needs to be intensified to create awareness among the inhabitants of Ho municipality of Ghana.It is imperative to educate Ghanaians and beyond about the risk factor associations that predispose an individual to DM.

P4346Religious education and midlife observance are associated with lower coronary heart disease (CHD) mortality 23 years later

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
S Eilat-Adar ◽  
U Goldbourt
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Socioeconomic Status ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Systolic Blood Pressure ◽  
Body Mass ◽  
Reference Group ◽  
Middle Aged

Abstract Objective To determine whether self-reported religiosity is associated with decreased coronary mortality risk in middle-aged men when rates are adjusted for known confounders. Design The Israeli Ischemic Heart Disease (IIHD) Project (n=10,232) was chosen by stratified sampling of civil servants and municipal male employees, men aged 40–65 in 1963. Subjects were seen upon enrollment (1963) and at two follow-up visits (1965 and 1968). Extent of religiosity according to belief and practice collected in 1965 on a scale from 1 to 5. Religiosity was defined as follow: (1) The most-strict observance of religious rules “Haredim”. (2) “Religious” (3) “Traditional” (4) “Secular” (5) The part of the latter who declared themselves to be “nonbelievers” were categorized as “agnostic”. Main outcome measure Coronary heart disease (CHD) death, determined from death certificates in 23 years of follow-up Results Among 9245 participants, 1098 died from CHD during 23 years follow up. Ever smoking, Body mass index (BMI) and socioeconomic status were significantly lower while age and diabetes were higher according to increasing religiosity. Religiosity was inversely related to CHD mortality. Demographic, anthropometric characteristics according to religion, and odds ratio (OR), 95% confidence interval (95% CI), for CHD mortality, (using agnostic as a reference group) are presented in table 1. Characteristics according to religion Religiosity Haredim (n=2103) Religious (n=1528) Traditional (n=1782) Secular (n=2085) Agnostic (n=1747) P for trend Age years (SD) 50.2 (6.9) 48.8 (6.6) 48.4 (6.7) 48.8 (6.6) 45.9 (6.8) <0.001 Ever smoking% 58.7 67.6 70.7 71.9 72.6 0.001 Systolic blood pressure (mmHg) 136 (21) 135 (20) 135 (21) 134 (20) 135 (20) 0.115 Diabetes (%) 9.8 11.1 8.3 8.8 6.5 <0.001 Socioeconomic status 2.2 (1.3) 2.3 (1.1) 2.7 (1.1) 2.7 (1.2) 3.1 (1.4) <0.001 BMI kg/m2 (SD) 22.5 (3.6) 25.9 (3.5) 25.9 (3.2) 25.6 (3.2) 25.4 (2.9) 0.028 Cholesterol (mg%) 201 (38) 207 (41) 208 (39) 214 (40) 218 (40) 0.001 Number of death (% category) 187 (8.9) 161 (10.5) 185 (10.4) 228 (10.9) 225 (12.9) <0.001 OR (95% CI)* 0.67 (0.53–0.85) 0.85 (0.67–1.08) 0.84 (0.67–1.05) 0.87 (0.71–1.08) 1 *Adjusted for age, cigarette smoking, systolic blood pressure, diabetes, socioeconomic status, body mass index and cholesterol. Conclusion Religiosity was associated with lower CHD death in employed middle aged Israeli men followed up prospectively for 23 years.

scholarly journals Shift Work Is a Risk Factor for Increased Blood Pressure in Japanese Men

Hypertension ◽  
2008 ◽  
Vol 52 (3) ◽  
pp. 581-586 ◽  
Author(s):  
Yasushi Suwazono ◽  
Mirei Dochi ◽  
Kouichi Sakata ◽  
Yasushi Okubo ◽  
Mitsuhiro Oishi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Risk Factor ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Body Mass ◽  
Shift Work ◽  
Total Serum ◽  
Japanese Men ◽  
End Points

To clarify the effect of shift work on blood pressure in Japanese men, a 14-year historical cohort study was conducted in day workers (n=3963) and alternating shift workers (n=2748) who received annual health checkups between 1991 and 2005 in a Japanese steel company. The end points were a ≥10%, ≥15%, ≥20%, ≥25%, or ≥30% increase in systolic blood pressure or diastolic blood pressure from baseline during the period of observation. The association between shift work and an increase in blood pressure was investigated adjusting for age, body mass index, hemoglobin A1c, total serum cholesterol, creatinine, aspartate aminotransferase, γ-glutamyl transpeptidase, uric acid, drinking habit, smoking habit, and habitual exercise by multivariate pooled logistic regression analyses. Shift work was significantly associated with the various end points. The odds ratios (and 95% CIs) were as follows: ≥10%, 1.15 (1.07 to 1.23); ≥15%, 1.21 (1.12 to 1.31); ≥20%, 1.15 (1.04 to 1.28); ≥25%, 1.20 (1.06 to 1.37); and ≥30%, 1.23 (1.03 to 1.47) for systolic blood pressure and ≥10%, 1.19 (1.11 to 1.28); ≥15%, 1.22 (1.13 to 1.33); ≥20%, 1.24 (1.13 to 1.37); and ≥25%, 1.16 (1.03 to 1.30) for diastolic blood pressure. Our study in male Japanese workers revealed that alternating shift work was a significant independent risk factor for an increase in blood pressure. Moreover, the effect of shift work on blood pressure was more pronounced than other well-established factors, such as age and body mass index.

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