Evolution of World and Brazilian Markets for Enzymes Produced by Solid-state Fermentation: A Patent Analysis

2020 ◽  
Vol 14 (2) ◽  
pp. 112-120
Author(s):  
Heb C.S.R. Rodrigues ◽  
Andrea L. Carvalho ◽  
Carolina O. Souza ◽  
Marcelo A. Umsza-Guez

Background: The use of enzymes in various industrial processes has become increasingly frequent. When added to productive processes, it can accelerate reactions and generate a number of new products. The solid state fermentation (SSF), among other applications, has been employed also to obtain enzymes. Objective: The purpose of this prospection was to map registered patent documents about enzymes production by this type of fermentation in the world, identify the most obtained enzymes with patent documents and compilate information about the world and Brazilian enzyme markets. Methods: The experimental design was carried out by the keyword-driven scope through the advanced search in the Espacenet database European Patent Office (EPO). The keywords selected were solid-state fermentation and the International Patent Classification code, C12N9 (enzymes; proenzymes), for prospecting of interest. Results: In 2012, there was the higher number of registered patents (12). China holds 84% of deposited patents. Among the types of depositors, 54% of the selected patent documents were deposited by universities and institutes, and 44% by companies. 76.5% of the evaluated patents used fungi as enzyme producer. Analyzing the enzymes obtained in the registered patents, it is verified that the majority belongs to the group of carbohydrases with 43%, followed by proteases (25%), which are also the two classes of enzymes most commercialized in the market. Conclusion: China holds the majority of the registered patents but North America gets the largest global enzyme market revenue followed by Europe and Pacific Asia. Carbohydrases were the most commercialized enzymes and with the highest number of patents registered. Among the carbohydrases, cellulases, xylanases and amylases are the most frequent in patent registration while being fungi produced.

2020 ◽  
Vol 14 (3) ◽  
pp. 184-193
Author(s):  
Brisa R.P. Gonçalves ◽  
Bruna A.S. Machado ◽  
Samira A. Hanna ◽  
Marcelo A. Umsza-Guez

Background: Colorant-producing microorganisms are quite common in nature. These biomolecules present many biological activities such as antitumoral, antimicrobial and antioxidant, in addition to the various nuances of color, making them of special technological importance to the industrial sectors. Objective: This study aims to conduct a technological mapping in the patent, at European patent Office (EPO), in order to evaluate the global panorama of the use of microbial colorants. Methods: The experimental design was acquired by the keyword-driven approach through the advanced search in the Espacenet database European Patent Office (EPO). The keywords selected were bacteria or fungi* or yeast or algae or microorganism* but not plant* and pigment* or color* or colorant* or dye* and the International Patent Classification code, C09B61, for prospecting of interest. Results: There has been a linear increase in patents developed in the last 20 years, with Japan as the largest depositor in the area. The companies Dainippon Ink and Chemicals and Ajinomoto, both being Japanese, are the largest depositors with 20% of all patents. Among the microorganisms, the filamentous fungi appeared in the first place with 32% of documents and the fungi of the genus Monascus were the most frequently used. Conclusion: The use of microbial colorants has been growing among industries, mainly in food sectors, due to the growing demand for products of natural origin. Thus, the increase in research and technological development in the area of microbial colorants can become an economically viable and promising strategy for the various industrial sectors.


Author(s):  
V. I. Evdokimov

Relevance. When working in hazardous conditions, eliminating accidents, fires and emergencies, personal respiratory protective equipment (RPE) helps optimize working capacity and preserve the health of workers and the population. The use of RPE is especially important in epidemics spreading by airborne droplets, i.e. in the pandemic of the coronavirus infection SARS-CoV-2. Intention. To analyze the development of patenting and types of inventions in the field of RPE in the world over 20 years from 2000 to 2019.Methodology. The object of the research was patents for inventions, in which headings included the types of respirators and gas masks according to the International Patent Classification (IPC). It should be noted that this classification is somewhat different from that adopted in Russia. Clarivate Analytics’ Derwent Innovations patent database was searched.Results and Discussion. The created search mode made it possible to find 5006 responses to patents for inventions, in which IPC headings were presented by types of respirators and gas masks. Annually, (250 ± 11) inventions with IPC headings by RPE type were paternted worldwide. The dynamics of patenting inventions resembles an inverted U-curve with maximum rates in 2014–2015 and some decrease in the last observation period. The largest contribution to the total array of inventions by RPE type was made by patent families affiliated with the United States (43.9 %), South Korea (22 %), Japan (21.2 %), China (19 %) and the European Patent Office (18.7 %). The structure of the analyzed inventions in the world included RPEs with compressed oxygen or air (7.5 %), with breathing-controlled valves dosing the supply of oxygen or air (4.4 %), with liquid oxygen (0.9 %), with oxygen-releasing chemicals (11.3 %), with filtering elements (20.6 %), hose (2.4 %), for high-altitude aircrafts (4.8%). RPE masks and RPE helmets accounted for 44.1 % and 4 %, respectively. There were regional differences in the patenting of inventions by RPE types.Conclusion. There were quite many domestic inventions on RPE with oxygen-releasing chemicals and with filter elements; the overall contribution of patented inventions in Russia for all RPE types was 6% of the total array.


2021 ◽  
Vol 10 (14) ◽  
pp. e333101422076
Author(s):  
Nathália Andrezza Carvalho de Souza ◽  
Victória Laysna dos Anjos Santos ◽  
Tarcísio Cícero de Lima Araújo ◽  
Pedrita Alves Sampaio ◽  
Renata Rivelli Menezes de Souza ◽  
...  

The genus Mikania (Asteraceae) comprises about 450 species of these, 203 are found in Brazil and present several chemical and biological activities. Considering the variety of species and their therapeutic properties, the present study aimed to perform technological prospecting of this genus, since this approach aims to contribute to technological, scientific and innovation research. For this purpose, the patent documents were analyzed, regarding the applicant countries, year of filing and the international classification of patents of the genus Mikania. The search was conducted in the databases World Intellectual Property Organization (WIPO), European Patent Office (EPO) and the National Institute of Industrial Property (INPI) in October 2020, using the descriptor “Mikania”; present in the title and/or abstract in addition, documents that included medicinal approaches were selected. Thus, taking into consideration the filing countries, Japan, Brazil and the United States led the patent deposits, with the first document filed in 1991 and the largest number of applications in the years 2000 and 2010. The data concerning the international patent classification are concentrated in subclass A61K, which deals with preparations for medical, dental or hygienic purposes. These results demonstrated the therapeutic and technological potential of the Mikania species and thus which can be evidenced the potential of this study.


2022 ◽  
pp. 532-542
Author(s):  
Pankaj Kumar ◽  
Ameeta Sharma

Numerous applications have been filed for patents based on bio-inventions in the Indian patent office. Although there is not any international patent, there is a system of international patent applications whereby the applicant may designate name of countries where they wish to file application for patents nationally. According to international patent classification, the concern class for such a patent applications is A61K36/00. More particularly, the international class (IC) A61K36/00 relates to medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof (e.g., traditional herbal medicines). International applications filings under patent cooperation treaty (PCT) for patent purposes can be accessed at the Patentscope (patent search tool of WIPO). All international patent applications for such TK-based inventions have been accessed online at Patentscope using the classification code A61K36 for this study.


2017 ◽  
Vol 20 ◽  
pp. 115 ◽  
Author(s):  
Lyghia Maria Araújo Meirelles ◽  
Fernanda Nervo Raffin

There has been a growing trend in recent years for the development of hybrid materials, called composites, based on clay and polymers, whose innovative properties render them attractive for drug release. The objective of this manuscript was to conduct a review of original articles on this topic published over the last decade and of the body of patents related to these carriers. A scientific prospection was carried out spanning the period from 2005 to 2015 on the Web of Science database. The technological prospection encompassed the United States Patent and Trademark Office, the European Patent Office, the World International Patent Office and the National Institute of Industrial Property databases, filtering patents with the code A61K. The survey revealed a rise in the number of publications over the past decade, confirming the potential of these hybrids for use in pharmaceutical technology. Through interaction between polymer and clay, the mechanical and thermal properties of composites are enhanced, promoting stable, controlled drugs release in biological media. The most cited clays analyzed in the articles was montmorillonite, owing to its high surface area and capacity for ion exchange. The polymeric part is commonly obtained by copolymerization, particularly using acrylate derivatives. The hybrid materials are obtained mainly in particulate form on a nanometric scale, attaining a modified release profile often sensitive to stimuli in the media. A low number of patents related to the topic were found. The World International Patent Office had the highest number of lodged patents, while Japan was the country which published the most patents. A need to broaden the application of this technology to include more therapeutic classes was identified. Moreover, the absence of regulation of nanomaterials might explain the disparity between scientific and technological output. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.


2012 ◽  
Vol 25 (4) ◽  
pp. 551-594 ◽  
Author(s):  
Hyo Yoon Kang

ArgumentRecent studies of patents have argued that the very materiality and techniques of legal media, such as the written patent document, are vital for the legal construction of a patentable invention. Developing the centrality placed on patent documents further, it becomes important to understand how these documents are ordered and mobilized. Patent classification answers the necessity of making the virtual nature of textual claims practicable by linking written inscription to bureaucracy. Here, the epistemological organization of documents overlaps with the grid of patent administration. How are scientific inventions represented in such a process? If we examine the process of creating a new patent category within the International Patent Classification (IPC), it becomes clear that disagreements about the substance of the novel inventive subject matter have been resolved by computer simulations of patent documents in draft classifications. The practical needs of patent examiners were the most important concerns in the making of a new category. Such a lack of epistemological mediation between the scientific and legal identities of an invention depicts a legal understanding that science is already inside patent law. From an internal legal perspective, the self-referential introduction of the new patent category may make practical sense; however it becomes problematic from a technological and scientific standpoint as the remit of the patent classification also affects other social contexts and practices.


2016 ◽  
Vol 31 (1) ◽  
Author(s):  
Rajendra Prasad

AbstractPatent classification systems have traditionally evolved independently at each patent jurisdiction to classify patents handled by their examiners to be able to search previous patents while dealing with new patent applications. As patent databases maintained by them went online for free access to public as also for global search of prior art by examiners, the need arose for a common platform and uniform structure of patent databases. The diversity of different classification, however, posed problems of integrating and searching relevant patents across patent jurisdictions. To address this problem of comparability of data from different sources and searching patents, WIPO in the recent past developed what is known as International Patent Classification (IPC) system which most countries readily adopted to code their patents with IPC codes along with their own codes. The Cooperative Patent Classification (CPC) is the latest patent classification system based on IPC/European Classification (ECLA) system, developed by the European Patent Office (EPO) and the United States Patent and Trademark Office (USPTO) which is likely to become a global standard. This paper discusses this new classification system with reference to patents on bioremediation.


2017 ◽  
Vol 3 (2) ◽  
pp. 38-51 ◽  
Author(s):  
Carlos Eduardo Collazo Pontes

The law of Generics allowed the growth of national industries, But investment in Research, Development and Innovation (P, D & I) remained practically null. Based on this scenario of fragility of the Brazilian industry, a research in database of patent documents, using as methodology, a search strategy, according to the International Patent Classification (IPC) was done. This survey, based on the analysis of the patent documents obtained, allowed us to reach the objective of the study, which is to introduce the situation of the national pharmaceutical industries in relation to investment in innovation. The results indicate the lack of investments in innovation in Brazil, allowing the conclusion that the country is totally dependent on the imports of medicines. This fact positions the multinational industries in a situation of superiority, facilitating the practice of abusive prices, since these take advantage of the patent protection.


PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254424
Author(s):  
Sungdo Jung ◽  
Keungoui Kim ◽  
Changjun Lee

This study aims to understand the nature of information and communication technology in technology convergence. We form a knowledge network by applying social network theories to Korean patent data collected from the European Patent Organization. A knowledge network consists of nodes representing technology sectors identified by their International Patent Classification codes and edges that link International Patent Classification codes when they appear concurrently in a patent. We test the proposed hypotheses using four indices (degree centrality, E-I index, entropy index, and clustering coefficient). The results show that information and communication technology is easily attached but tends to converge with similar technology and has the greatest influence on technology convergence over other technologies. This study is expected to help practitioners and policymakers understand the structure and interaction mechanisms of technology from a systematic perspective and improve national-level technology policies.


2022 ◽  
Author(s):  
Yuki Hoshino ◽  
Yoshimasa Utsumi ◽  
Yoshiro Matsuda ◽  
Yoshitoshi Tanaka ◽  
Kazuhide Nakata

Abstract International patent classifications (IPCs) are assigned to patent documents; however, since the procedure for assigning classifications is manually done by the patent examiner, it takes a lot of time and effort to select some IPCs from about 70,000 IPCs. Hence, some research has been conducted on patent classification with machine learning. However, patent documents are very voluminous, and learning with all the claims (the part describing the content of the patent) as input would run out of the necessary memory. Therefore, most of the existing methods learn by excluding some information, such as using only the first claim as input. In this study, we propose a model that considers the contents of all claims by extracting important information for input. We also propose a new decoder that considers the hierarchical structure of the IPC. Finally, we evaluate the model using an evaluation index that assumes the actual use of IPC selection for patent documents.


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