Evaluation of the Technological Potential of Grape Peels Through Patent Document Analysis: Agro-industrial Waste with Biotechnological Potential

2020 ◽  
Vol 14 ◽  
Author(s):  
Euzelia Lima de Souza ◽  
Ingrid Lessa Leal ◽  
Marcelo Andres Umsza-Guez ◽  
Bruna Aparecida Souza Machado
Keyword(s):  
Waste Product ◽  
The United States ◽  
Industrial Applications ◽  
Natural Form ◽  
Beneficial Effects ◽  
Research Technology ◽  
Technological Potential ◽  
Promising Area ◽  
Patent Documents ◽  
Grape Peel

Background: Grape (Vitis viniferaL.) is consumed by old world populations in its natural form and is used to produce wine or juice. Currently, China is the largest grape producer in the world. The red grapes stand out because of their phytochemical composition, more specifically their high resveratrol levels. Resveratrol is a compound that has a number of different beneficial effects on health and is mainly used in the food and cosmetic industries. Grape peel is a waste product and new strategies based on nanotechnology can minimize its environmental impact and add value to this residue. Objectives: The first objective of this study was to evaluate the technological potential of utilizing grape peel by researching and analyzing information extracted from patent documents filed worldwide in order to identify the main countries that hold the research technology, the main depositors and inventors, and the main areas of application. The second aim was to research and investigate grape peel products that have been created using nanotechnology. Methods: An analysis of all patented documents related to grape peel processes, products, or different industrial applications that may use nanotechnology was carried out. This was achieved by undertaking a Derwent Innovation Index (DII) database search. Results: A total of 752 patent documents were identified in the surveyed area. These were assessed for depositor country of origin, type of depositor, inventors, evolution of deposits over time, and areas of application. Only 6% of the total represented products and processes in the nanotechnology area. There was a growth in the number of patent filings from 2015, which showed that the researched area is a current and developing technology with new application possibilities. The main depositing countries were China, the United States, and Japan, which dominate the researched technology. The identified documents discussed using grape peel to develop new food, medical and dental products. Conclusion: Over the last few years, different approaches have been suggested for the production of nanoproducts based on grape peel. The results from this study showed that although incipient, nanotechnology is a promising area of research that can be explored by universities and companies because the products could have significant positive characteristics and, even though they are made out of a byproduct, have great application potential.

Technological Potential of Avocado Oil: Prospective Study Based on Patent Documents

2019 ◽  
Vol 13 (4) ◽  
pp. 304-315
Author(s):  
Valente Chaves Gabriela ◽  
Nery Tatiana Barreto Rocha ◽  
Barreto Gabriele de Abreu ◽  
Reis João Henrique de Oliveira ◽  
Cerqueira Jamile Costa ◽  
...  
Keyword(s):  
The United States ◽  
Persea Americana ◽  
The European Union ◽  
Tropical Fruit ◽  
Avocado Oil ◽  
Technological Potential ◽  
The World ◽  
Promising Area ◽  
Patent Documents ◽  
Avocado Seed

Background: Avocado (Persea Americana, Mill.), belonging to the Lauraceae family, is considered a tropical fruit originating in Central America, with Mexico being the largest producer in the world. The fruit stands out for its economic potential and high nutritional value and its oil has good commercial value, however, its production is still incipient, being mainly used by the pharmaceutical and cosmetic industries. Despite producing a significant amount of oil, the avocado seed is still considered a by-product of fruit processing. Methods: Thus, the objective of this work was to evaluate the technological potential of the oil obtained from the avocado and avocado seed through the research and analysis of patent documents available worldwide, in order to identify the main countries that have the technology researched as well as, the main areas of application. We revised all the patents related to acquisition, application and the use of avocado oil. For this, a search was carried out for the database of the Derwent Innovation Index (DII), which compiles the collection of documents published around the world. Results: A total of 144 patent documents were identified, which were evaluated for the country of origin of thepublisher, the type of thepublisher, inventors, rate of publication over time and areas of application. There has been an increase in the number of patents producded as of 2011, which proves it to be a current and interesting technology. The main countries were the United States and the European Union. Conclusion: The documents identified referred to different processes applied to obtain oil, as well as the application for the development of new food, cosmetic and veterinary products. In this way, although incipient, the researched technology proved to be a promising area of research to be explored by universities and companies in view of the characteristics and potential of the product.

scholarly journals Does Person Organization Fit and Person-Job Fit Mediate the Relationship between Public Service Motivation and Work Stress among U.S. Federal Employees?

2021 ◽  
Vol 11 (2) ◽  
pp. 37
Author(s):  
Leonard Bright
Keyword(s):  
Work Stress ◽  
Public Service ◽  
High Stress ◽  
The United States ◽  
Public Organizations ◽  
Public Service Motivation ◽  
Public Employees ◽  
Federal Employees ◽  
Beneficial Effects ◽  
Indirect Relationship

A plethora of research has extolled the benefits of public service motivation (PSM) in public organizations. However, much less empirical attention has focused on its relationship to work stress. Even though it has been theorized that high levels of PSM causes individuals to be more resilient in stressful public service work environments, empirical research has failed to provide support. Only one study has been conducted which has revealed that high levels of PSM is directly associated with high levels of job stress among public employees, but that its beneficial effects are partially mediated by person-organization (PO) fit. That is, employees with high levels of PSM and high levels of fit to their organizations did not appear to suffer from high stress. This study sought to add to this limited body of research and explore the extent to which person-job (PJ) improves the field’s understanding of the relationships among PSM, PO fit, and work stress. Based on a sample of federal employees in the United States, this study challenged and confirmed the findings of existing research. For instance, PSM had no direct relationship to work stress. However, PSM maintained an indirect relationship to stress through PO fit. The respondents with high levels of PSM reported that they had high levels of fit to their organizations which was associated with significantly lower levels of work stress. Similarly, PSM was not directly related to PJ fit, but was indirectly related through its association with PO fit. PSM was associated with high levels of fit between employees and public organizations, which was subsequently associated with high levels of fit with public service jobs and lower work stress. Above all, this research clarifies the process of how PSM influences work stress among public employees, through PO fit and PJ fit.

scholarly journals The National Earth System Prediction Capability: Coordinating the Giant

2017 ◽  
Vol 98 (2) ◽  
pp. 239-252 ◽  
Author(s):  
Jessie C. Carman ◽  
Daniel P. Eleuterio ◽  
Timothy C. Gallaudet ◽  
Gerald L. Geernaert ◽  
Patrick A. Harr ◽  
...  
Keyword(s):  
Numerical Weather Prediction ◽  
Weather Prediction ◽  
The United States ◽  
Department Of Energy ◽  
Earth System ◽  
Numerical Weather ◽  
Interagency Coordination ◽  
Research Technology ◽  
Prediction Capability ◽  
The U.S

Abstract The United States has had three operational numerical weather prediction centers since the Joint Numerical Weather Prediction Unit was closed in 1958. This led to separate paths for U.S. numerical weather prediction, research, technology, and operations, resulting in multiple community calls for better coordination. Since 2006, the three operational organizations—the U.S. Air Force, the U.S. Navy, and the National Weather Service—and, more recently, the Department of Energy, the National Aeronautics and Space Administration, the National Science Foundation, and the National Oceanic and Atmospheric Administration/Office of Oceanic and Atmospheric Research, have been working to increase coordination. This increasingly successful effort has resulted in the establishment of a National Earth System Prediction Capability (National ESPC) office with responsibility to further interagency coordination and collaboration. It has also resulted in sharing of data through an operational global ensemble, common software standards, and model components among the agencies. This article discusses the drivers, the progress, and the future of interagency collaboration.

MOTHER FIGHTS TO RUIN THE TASTE OF POISON

PEDIATRICS ◽  
1989 ◽  
Vol 84 (4) ◽  
pp. A42-A42
Author(s):  
J. F. L.
Keyword(s):  
Public Service ◽  
Executive Director ◽  
The United States ◽  
Public Television ◽  
Small Children ◽  
Nail Polish ◽  
Household Products ◽  
Promising Area ◽  
Poison Prevention ◽  
Flavoring Agent

On March 6, a mother in Oregon watched a public television report about British companies that were discouraging children from eating poisonous household products by lacing them with Bitrex, the world's bitterest flavoring agent. The woman, Lynn Tylczak, who has two small children and lives in Albany, 60 miles south of Portland, began a letter-writing campaign that is focusing attention on poison prevention. She may also be speeding Bitrex's journey to supermarket shelves in products like detergents, nail-polish removers, rodenticides and antifreeze. "Mrs. Tylczak has already achieved a certain victory by bringing national attention to this issue," said Linda Golodner, executive director of the National Consumers League in Washington. "She has shown that a single consumer can make a difference." Now she is encouraging manufacturers to add Bitrex to their products by sharing with them letters of support that are sent to her group, the Poison-Proff Project (4384 S.E. Ermine Street, Albany, Ore. 97321). `A Very Promising Area' Consumer and safety organizations in the United States are beginning to notice. On May 5, the National Safety Council, a 13,000-member public-service organization, called on manufacturers to use Bitrex in all appropriate household products. "Bitrex is the most bitter substance known to man," according to the Merck Index. In 1982, some British companies began using Bitrex in household products to deter inquisitive children, but the practice did not grow until two years ago, when the Royal Society for the Prevention of Accidents endorsed its use.

scholarly journals Properties of a new fungal b-galactosidase with potential application in the dairy industry

1999 ◽  
Vol 30 (3) ◽  
pp. 265-271 ◽  
Author(s):  
Rubens Cruz ◽  
Vinícius D'Arcádia Cruz ◽  
Juliana Gisele Belote ◽  
Marcelo de Oliveira Khenayfes ◽  
Claudia Dorta ◽  
...  
Keyword(s):  
Hydrolytic Activity ◽  
Industrial Applications ◽  
Transferase Activity ◽  
Optimum Temperature ◽  
Milk Whey ◽  
Beneficial Effects ◽  
Optimum Ph ◽  
Semi Solid ◽  
Good Productivity ◽  
Hydrolysis Of

<FONT FACE="Symbol">b</font>-Galactosidase or <FONT FACE="Symbol">b</font>-D-galactoside-galactohydrolase (EC. 3.2.1.23) is an important enzyme industrially used for the hydrolysis of lactose from milk and milk whey for several applications. Lately, the importance of this enzyme was enhanced by its galactosyltransferase activity, which is responsible for the synthesis of transgalactosylated oligosaccharides (TOS) that act as functional foods, with several beneficial effects on consumers. Penicillium simplicissimum, a strain isolated from soil, when grown in semi-solid medium showed good productivity of <FONT FACE="Symbol">b</font>-galactosidase with galactosyltransferase activity. The optimum pH for hydrolysis was in the 4.04.6 range and the optimum pH for galactosyltransferase activity was in the 6.07.0 range. The optimum temperature for hydrolysis and transferase activity was 55-60°C and 50°C, respectively, and the enzyme showed high thermostability for the hydrolytic activity. The enzyme showed a potential for several industrial applications such as removal of 67% of the lactose from milk and 84% of the lactose from milk whey when incubated at their original pH (4.5 and 6.34, respectively) under optimum temperature conditions. When incubated with a 40% lactose solution in 150 mM McIlvaine buffer, pH 4.5, at 55°C the enzyme converted 86.5% of the lactose to its component monosaccharides. When incubated with a 60% lactose solution in the same buffer but at pH 6.5 and 50°C, the enzyme can synthetize up to 30.5% TOS, with 39.5% lactose and 30% monosaccharides remaining in the preparation.

The United States Navy “Standard Day” for Marine Gas Turbines

2017 ◽  
Author(s):  
John Hartranft ◽  
Bruce Thompson ◽  
Dan Groghan
Keyword(s):  
United States ◽  
Gas Turbine ◽  
United States Navy ◽  
Gas Turbines ◽  
The United States ◽  
Industrial Applications ◽  
Jet Engines ◽  
Jet Engine ◽  
Advantages And Disadvantages ◽  
Power Capability

Following the successful development of aircraft jet engines during World War II (WWII), the United States Navy began exploring the advantages of gas turbine engines for ship and boat propulsion. Early development soon focused on aircraft derivative (aero derivative) gas turbines for use in the United States Navy (USN) Fleet rather than engines developed specifically for marine and industrial applications due to poor results from a few of the early marine and industrial developments. Some of the new commercial jet engine powered aircraft that had emerged at the time were the Boeing 707 and the Douglas DC-8. It was from these early aircraft engine successes (both commercial and military) that engine cores such as the JT4-FT4 and others became available for USN ship and boat programs. The task of adapting the jet engine to the marine environment turned out to be a substantial task because USN ships were operated in a completely different environment than that of aircraft which caused different forms of turbine corrosion than that seen in aircraft jet engines. Furthermore, shipboard engines were expected to perform tens of thousands of hours before overhaul compared with a few thousand hours mean time between overhaul usually experienced in aircraft applications. To address the concerns of shipboard applications, standards were created for marine gas turbine shipboard qualification and installation. One of those standards was the development of a USN Standard Day for gas turbines. This paper addresses the topic of a Navy Standard Day as it relates to the introduction of marine gas turbines into the United States Navy Fleet and why it differs from other rating approaches. Lastly, this paper will address examples of issues encountered with early requirements and whether current requirements for the Navy Standard Day should be changed. Concerning other rating approaches, the paper will also address the issue of using an International Organization for Standardization, that is, an International Standard Day. It is important to address an ISO STD DAY because many original equipment manufacturers and commercial operators prefer to rate their aero derivative gas turbines based on an ISO STD DAY with no losses. The argument is that the ISO approach fully utilizes the power capability of the engine. This paper will discuss the advantages and disadvantages of the ISO STD DAY approach and how the USN STD DAY approach has benefitted the USN. For the future, with the advance of engine controllers and electronics, utilizing some of the features of an ISO STD DAY approach may be possible while maintaining the advantages of the USN STD DAY.

scholarly journals Technological prospection: the genus Mikania in therapeutic use

2021 ◽  
Vol 10 (14) ◽  
pp. e333101422076
Author(s):  
Nathália Andrezza Carvalho de Souza ◽  
Victória Laysna dos Anjos Santos ◽  
Tarcísio Cícero de Lima Araújo ◽  
Pedrita Alves Sampaio ◽  
Renata Rivelli Menezes de Souza ◽  
...  
Keyword(s):  
Biological Activities ◽  
The United States ◽  
World Intellectual Property Organization ◽  
European Patent ◽  
Industrial Property ◽  
Patent Classification ◽  
Innovation Research ◽  
Technological Potential ◽  
International Patent

The genus Mikania (Asteraceae) comprises about 450 species of these, 203 are found in Brazil and present several chemical and biological activities. Considering the variety of species and their therapeutic properties, the present study aimed to perform technological prospecting of this genus, since this approach aims to contribute to technological, scientific and innovation research. For this purpose, the patent documents were analyzed, regarding the applicant countries, year of filing and the international classification of patents of the genus Mikania. The search was conducted in the databases World Intellectual Property Organization (WIPO), European Patent Office (EPO) and the National Institute of Industrial Property (INPI) in October 2020, using the descriptor “Mikania”; present in the title and/or abstract in addition, documents that included medicinal approaches were selected. Thus, taking into consideration the filing countries, Japan, Brazil and the United States led the patent deposits, with the first document filed in 1991 and the largest number of applications in the years 2000 and 2010. The data concerning the international patent classification are concentrated in subclass A61K, which deals with preparations for medical, dental or hygienic purposes. These results demonstrated the therapeutic and technological potential of the Mikania species and thus which can be evidenced the potential of this study.

scholarly journals Mission-Oriented Innovation Policies in Austria – a case study for the OECD

2020 ◽  
Author(s):  
Peter Biegelbauer ◽  
◽  
Christian Hartmann ◽  
Wolfgang Polt ◽  
Anna Wang ◽  
...  
Keyword(s):  
Innovation Policy ◽  
Technological Development ◽  
The United States ◽  
Government Interventions ◽  
Technology And Innovation ◽  
Research Technology ◽  
Research And Innovation ◽  
National Debate ◽  
Policy Agendas ◽  
Innovation Policies

In recent years, mission-oriented approaches have received growing interest in science, technology and innovation (STI) policies against the background of two developments. First, while so-called “horizontal” or “generic” approaches to research, technology and innovation policies have largely been successful in improving the general innovation performance or the rate of innovation, there are perceived limitations in terms of insufficiently addressing the direction of technological change and innovation. Second, “grand societal challenges” emerged on policy agendas, such as climate change, security, food and energy supply or ageing populations, which call for thematic orientation and the targeting of research and innovation efforts. In addition, the apparent success of some mission-oriented initiatives in countries like China, South Korea, and the United States in boosting technological development for purposes of strengthening competitiveness contributed to boosting the interest in targeted and directional government interventions in STI. Against the backdrop of this renewed interest in mission-oriented STI policy, the OECD has addressed the growing importance of this topic and launched a project looking into current experiences with Mission-Oriented Innovation Policy (MOIP). The present study on MOIP in Austria was commissioned by the Austrian Federal Ministry for Climate Action, Energy, Mobility, Environment, Innovation and Technologiy (BMK) and comprises the Austrian contributions to this OECD project. The study aims at contributing Austrian experiences to the international debate and to stimulate a national debate on MOIP.

Seaweeds – a potential source of food, feed and fertiliser

2021 ◽  
Vol 45 (03) ◽  
pp. 19-25
Author(s):  
Devinder Dhingra ◽  
K. Kandiannan
Keyword(s):  
Food Additives ◽  
Soil Health ◽  
Essential Amino Acids ◽  
Industrial Applications ◽  
The Philippines ◽  
Fish Feed ◽  
Red Seaweeds ◽  
Beneficial Effects ◽  
Commercial Cultivation ◽  
The World

Many communities in the world consume naturally growing and cultivated/ farmed seaweeds as food. Currently, commercial cultivation/farming produces more than 96% of seaweeds in the world and only around 3-4% is obtained from wild harvest (noncultivated). Naturally occurring and cultivated seaweeds are categorized into green, brown and red seaweeds, based on their pigmentation. More than 200 species of seaweeds are of commercial value, but only around 10 species of seaweeds are popularly cultivated. China, Indonesia, the Republic of Korea and the Philippines are the leading producers of cultured/ farmed species (viz. Eucheuma, Japanese kelp, Gracilaria, Unndaria pinnatifid); and Chile, China and Norway for wild species (mainly brown and red) and Chilean kelp. Seaweeds are rich in dietary fiber (polysaccharides), essential amino acids, major and micronutrients (minerals), vitamins etc. It has been reported that some species are a good source of plant growth regulators. Mainly, the people in China, Japan and Korea relish the soups, stews, flakes, coatings, snacks, etc., made from seaweeds. The use of seaweeds as human food in India is not very common. The second major use of seaweeds after food is the extraction of three important hydrocolloids (Agar, Alginate and Carrageenan). These are used as food additives and in many other industrial applications. A small portion of seaweed is used as an ingredient as livestock feed and fish feed. Seaweed meal and liquid extract of seaweed have been tried in conjunction with inorganic fertilizers with beneficial effects on crop yield, quality produce and soil health. Seaweed is an important marine resource and the coastline in India can be utilized to commercially cultivate seaweed species beneficial for human health and plants. Research is required in developing functional foods, health foods and nutraceuticals from seaweeds to improve the health and nutritional status of the human population. This paper briefly describes the status of production and utilization of seaweeds in different parts of the world.

Analyzing nanoparticle-induced neurotoxicity: A bibliometric analysis

2020 ◽  
Vol 36 (1) ◽  
pp. 22-29
Author(s):  
Xiaomin Wei ◽  
Fuzhen Yang ◽  
Defang Chen ◽  
Jun Li ◽  
Xiaohong Shi ◽  
...  
Keyword(s):  
Web Of Science ◽  
Amyloid Β ◽  
Research Direction ◽  
The United States ◽  
Research Area ◽  
Signal Pathways ◽  
Amyloid Β Protein ◽  
Β Protein ◽  
Promising Area ◽  
Species Production

Background: In recent years, nanoparticles have been widely used in many fields, ranging from cosmetics, agriculture, environment, and biomedical areas. The increasing use of nanoproducts induces a potential increasing exposure to human body, and then, unknown pathological consequences could increase. Methods: The database was searched from 2008 to 2018 by the Web of Science Core Collection. The bibliometric methods, CiteSpace and HistCite, were used for analysis and visualization of the data. Results: The 2932 publications were analyzed and the annual publications grew from 78 to 512 in a decade. The United States and China mainly contribute to this research area, which accounted for 29.5% and 22.9%, respectively. PLoS One, Scientific Reports, and Nanoscale were the three journals that published the most articles. Keyword analysis indicated that the major research direction was the mechanisms of nanoneurotoxicity, which included oxidative stress, inflammation, astrocyte activation, and the fibrillation of amyloid β protein. Conclusion: This bibliometric study revealed that nanoneurotoxicity was still a research hot topic and could be a promising area of research in the next few years. Nanoparticles play a role in neurodegenerative diseases by inducing reactive oxygen species production, inflammation, alterations of gene expression, and signal pathways.

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