scholarly journals Two Valid Measures of Self-rated Physical Activity and Capacity

2012 ◽  
Vol 6 (1) ◽  
pp. 156-162 ◽  
Author(s):  
Marit Sundal Holen ◽  
Rønnaug Een ◽  
Thomas Mildestvedt ◽  
Geir Egil Eide ◽  
Eivind Meland
Keyword(s):  
Physical Activity ◽  
Biological Markers ◽  
Cardiovascular Health ◽  
Hdl Cholesterol ◽  
Rehabilitation Program ◽  
Model Assessment ◽  
Homeostatic Model Assessment ◽  
And Biological Markers ◽  
Short Versions ◽  
Homa Score

Objectives: Questionnaires on physical activity (PA) and physical capacity (PC) are valuable tools, as they are cost beneficial, and have high response rates. The validity of short versions of such questionnaires has not been examined satisfactorily. Therefore, we aimed at examining the validity of a set of questions coding for PA and PC. Design: The questions were administered to 217 men and women attending a cardiac rehabilitation program. Participants also gave blood samples, measuring HDL cholesterol, triglycerides (TG), insulin, glucose, and microCRP. The relations between PA and PC and biological markers were examined by linear regression analyses. Results: Measures for PC and for PA were identified by factor analysis, which proved internally consistent. TG, homeostatic model assessment (HOMA) score, and mCRP were all significantly associated with the measures of PC and PA. Conclusions: The measures of PA and PC are valid compared with biological markers, allowing cost-beneficial and time-efficient evaluation of important measures for cardiovascular health.

scholarly journals Physical Activity, Physical Performance, and Biological Markers of Health among Sedentary Older Latinos

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Gerardo Moreno ◽  
Carol M. Mangione ◽  
Pin-Chieh Wang ◽  
Laura Trejo ◽  
Anthony Butch ◽  
...  
Keyword(s):  
Physical Activity ◽  
Waist Circumference ◽  
Physical Performance ◽  
Biological Markers ◽  
Hdl Cholesterol ◽  
Activity Level ◽  
Cross Sectional ◽  
Metabolic Markers ◽  
Reactive Protein ◽  
And Biological Markers

Background. Physical activity is associated with better physical health, possibly by changing biological markers of health such as waist circumference and inflammation, but these relationships are unclear and even less understood among older Latinos—a group with high rates of sedentary lifestyle.Methods. Participants were 120 sedentary older Latino adults from senior centers. Community-partnered research methods were used to recruit participants. Inflammatory (C-reactive protein) and metabolic markers of health (waist circumference, HDL-cholesterol, triglycerides, insulin, and glucose), physical activity (Yale physical activity survey), and physical performance (short physical performance NIA battery) were measured at baseline and 6-month followup.Results. Eighty percent of the sample was female. In final adjusted cross-sectional models, better physical activity indices were associated with faster gait speed (P<0.05). In adjusted longitudinal analyses, change in self-reported physical activity level correlated inversely with change in CRP (β=-0.05;P=0.03) and change in waist circumference (β=-0.16;P=0.02). Biological markers of health did not mediate the relationship between physical activity and physical performance.Conclusion. In this community-partnered study, higher physical activity was associated with better physical performance in cross-sectional analyses. In longitudinal analysis, increased physical activity was associated with improvements in some metabolic and inflammatory markers of health.

Physical activity, physical fitness, and cardiovascular health

2013 ◽  
Author(s):  
Jos Twisk ◽  
Isabel Ferreira
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Physical Fitness ◽  
Children And Adolescents ◽  
Cardiovascular Health ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Apo B

The incidence of morbidity and mortality related to CVD is rather low in a paediatric population. Studies investigating the relationship between physical activity, physical fitness, and cardiovascular health in children and adolescents are therefore mostly limited to CVD risk factors as outcome measures. For this reason, this chapter will focus on the association of physical activity and physical fitness with CVD risk factors in children and adolescents. These risk factors can be divided into the so-called traditional CVD risk factors; that is, lipoproteins [total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides (TG)], blood pressure, body fatness, and diabetes, and ‘new’ CVD risk factors; that is, other lipoproteins [lipoprotein(a) (Lp(a)), apolipoprotein (apo)B, and apoA-1], coagulation and inflammation markers [fibrinogen, C-reactive protein (CRP)], homocysteine, and heart rate variability.

Dual activity of serum lipoprotein-associated phospholipase A2 yielding positive and inverse associations with cardiometabolic risk

2011 ◽  
Vol 49 (8) ◽  
Author(s):  
Altan Onat ◽  
Gülay Hergenç ◽  
Günay Can ◽  
Murat Uğur ◽  
Filiz Nartop
Keyword(s):  
Cardiometabolic Risk ◽  
Inverse Correlation ◽  
Hdl Cholesterol ◽  
Serum Lipoprotein ◽  
Model Assessment ◽  
Apolipoprotein C ◽  
Homeostatic Model Assessment ◽  
Low Hdl ◽  
Homeostatic Model ◽  
High Triglyceride

AbstractThe clinical relevance of serum lipoprotein-associated phospholipase AIn 736 Turkish adults, serum total Lp-PLASignificant inverse correlation existed with high triglyceride/low HDL cholesterol dyslipidemia, waist girth, apolipoprotein C-III, homeostatic model assessment, and linear inverse associations in women with lipoprotein (a) and fibrinogen, suggesting that Lp-PLASerum total Lp-PLA

scholarly journals Using Isotemporal Analyses to Examine the Relationships Between Daytime Activities and Cancer Recurrence Biomarkers in Breast Cancer Survivors

2020 ◽  
Vol 17 (2) ◽  
pp. 217-224
Author(s):  
Kelsie M. Full ◽  
Eileen Johnson ◽  
Michelle Takemoto ◽  
Sheri J. Hartman ◽  
Jacqueline Kerr ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Light Intensity ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Cancer Recurrence ◽  
Model Assessment ◽  
Homeostatic Model Assessment ◽  
Intensity Physical Activity ◽  
Homeostatic Model

Background: For breast cancer survivors, moderate to vigorous physical activity (MVPA) is associated with improved survival. Less is known about the interrelationships of daytime activities (sedentary behavior [SB], light-intensity physical activity, and MVPA) and associations with survivors’ health outcomes. This study will use isotemporal substitution to explore reallocations of time spent in daytime activities and associations with cancer recurrence biomarkers. Methods: Breast cancer survivors (N = 333; mean age 63 y) wore accelerometers and provided fasting blood samples. Linear regression models estimated the associations between daytime activities and cancer recurrence biomarkers. Isotemporal substitution models estimated cross-sectional associations with biomarkers when time was reallocated from of one activity to another. Models were adjusted for wear time, demographics, lifestyle factors, and medical conditions. Results: MVPA was significantly associated with lower insulin, C-reactive protein, homeostatic model assessment of insulin resistance, and glucose, and higher sex hormone-binding globulin (all P < .05). Light-intensity physical activity and SB were associated with insulin and homeostatic model assessment of insulin resistance (both P < .05). Reallocating 18 minutes of SB to MVPA resulted in significant beneficial associations with insulin (−9.3%), homeostatic model assessment of insulin resistance (−10.8%), glucose (−1.7%), and sex hormone-binding globulin (7.7%). There were no significant associations when 79 minutes of SB were shifted to light-intensity physical activity. Conclusions: Results illuminate the possible benefits for breast cancer survivors of replacing time spent in SB with MVPA.

scholarly journals RELATIONSHIP BETWEEN THE ALLOY FREQUENCY OF THE T102C POLYMORPHISM OF THE 5HT2A GENE WITH ANTHROPOMETRIC AND CARDIOMETABOLIC MEASURES

2019 ◽  
Vol 1 (2) ◽  
pp. 157-170
Author(s):  
BLK Mallmanna ◽  
CRA Tonini ◽  
EO Chielle ◽  
Eduardo Ottobelli Chielle
Keyword(s):  
Diastolic Pressure ◽  
Hdl Cholesterol ◽  
Model Assessment ◽  
Anthropometric Parameters ◽  
Allele Distribution ◽  
Homeostatic Model Assessment ◽  
T102c Polymorphism ◽  
Relationship Of ◽  
The Relationship ◽  
Anthropometric Markers

Obesity is a disease characterized by excessive body fat. Among the neurobiological factors associated with obesity, the serotonergic system stands out. The neurotransmitter of these circuits is serotonin (5-HT). Decreased levels of 5-HT have been linked to increased desire to ingest sweets and carbohydrates. This study aims to verify the relationship of the 5HT2A T102C gene polymorphism with obesity and anthropometric parameters. Blood samples and anthropometric data were collected from 150 volunteers, divided between the control and obese groups. The results showed that for individuals with diastolic pressure (p = 0.3681), Estimated Mean Glycemia (GMe) (p = 0.0228) and Homeostatic Model Assessment (HOMA-IR-IR) (p = 0.001) all altered, a higher frequency of C alleles was observed. For normal GMe (p = 0.0270), a higher frequency of the T allele was observed. There was no difference for the allele distribution between the normal and altered groups for the parameters of Triglycerides, HDL cholesterol, total cholesterol, glycated hemoglobin and Insulin. The distribution of the alleles between the groups, normal diastolic pressure (p = 0.3681) and HOMA-IR (p = 0.9203) groups presented no difference. From the genotypic analyzes of the T102C polymorphism of the 5HT2A gene, it was possible to demonstrate a relationship between the presence of the C allele with biochemical and anthropometric markers related to obesity and hypertension.

Effects of an EE/CA compared with EE/CA-metformin on serum ADMA levels in women with polycystic ovary syndrome

Open Medicine ◽  
2009 ◽  
Vol 4 (4) ◽  
pp. 423-427 ◽  
Author(s):  
Levent Kebapcilar ◽  
Arif Yuksel ◽  
Giray Bozkaya ◽  
Cuneyt Taner ◽  
Ayse Kebapcilar ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Hdl Cholesterol ◽  
Model Assessment ◽  
Ovary Syndrome ◽  
Treatment Groups ◽  
Cholesterol Levels ◽  
Metformin Group ◽  
Homeostatic Model Assessment ◽  
Pre Treatment

AbstractTo determine the effects of EE/CA (Ethinylestradiol/ Cyproterone Acetate) and EE/CA-metformin treatments on the asymmetric dimethylarginine (ADMA) levels in women with PCOS (Polycystic Ovary Syndrome). Among 43 patients diagnosed with PCOS, one study arm (n=22) was administered (35 µg EE, 2mg CA) and the other (n=21) was administered (35 µg EE, 2mg CA plus 1700mg metformin). Serum ADMA, lipid profile, androgens, insulin, and HOMA-IR (Homeostatic Model Assessment of Insulin Resistance ) values were assessed prior to treatment and after 3 months of therapy. A significant reduction in ADMA levels relative to pre-treatment in the EE/CA+metformin group (1.2±0.4 vs 0.95±0.4, p=0.016) compared to the EE/CA group (1.0±0.5 vs 1.03±0.4, p >0.05). Andogens, insulin and HOMA-IR levels decreased in both treatment groups. All lipid profiles significantly improved in-group EE/CA+metformin while no significant decrease was observed in TG and HDL-cholesterol levels in EE/CA group. Post-treatment levels of HDL-C levels correlated significantly with the reducing ADMA levels in the EE/CA+metformin group (P=0.005, r= 0.602). Adding metformin to EE/CA therapy in PCOS may beneficial endothelium effects associated with reduction of ADMA levels.

scholarly journals Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2310
Author(s):  
Mai Matsumoto ◽  
Naoko Waki ◽  
Hiroyuki Suganuma ◽  
Ippei Takahashi ◽  
Sizuka Kurauchi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Diseases ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Healthy Population ◽  
Model Assessment ◽  
Young Males ◽  
Homeostatic Model Assessment ◽  
Carotenoid Level

Several studies have demonstrated that carotenoid-rich vegetables are useful against cardiovascular diseases (CVDs). However, it is still unclear when a healthy population should start eating these vegetables to prevent CVDs. In this study, we evaluated the role of carotenoids in CVD markers in healthy subjects using age-stratified analysis. We selected 1350 subjects with no history of apparent illness who were undergoing health examinations. We then evaluated the relationship between the serum concentrations of six major carotenoids as well as their total, and nine CVD markers (i.e., body mass index (BMI), pulse wave velocity (PWV), systolic blood pressure (SBP), diastolic blood pressure (DBP), Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), blood insulin, fasting blood glucose (FBG), triglycerides (TGs), and high-density lipoprotein (HDL) cholesterol) using multiple regression analysis. It was found that the total carotenoid level was significantly associated with seven markers other than BMI and FBG in males and with eight markers other than DBP in females. Many of these relationships were independent of lifestyle habits. Many significant relationships were found in young males (aged 20–39) and middle-aged females (aged 40–59). These findings can be used as lifestyle guidance for disease prevention although the causal relationships should be confirmed.

Association between accelerometer-assessed physical activity and biological markers among adults with HIV

2013 ◽  
Vol 12 (2) ◽  
pp. 33-38
Author(s):  
Paul D. Loprinzi, PhD ◽  
Carissa Martin, BA ◽  
Christy Kane, PhD ◽  
Jerome F. Walker, EdD
Keyword(s):  
Physical Activity ◽  
T Cells ◽  
Biological Markers ◽  
Cd4 T Cells ◽  
Fasting Glucose ◽  
Vigorous Physical Activity ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
And Biological Markers ◽  
The Many

The purpose of this study was to examine the association between physical activity and CD4+ T cells and various biological markers among those with HIV. Data from the 2003- 2006 National Health and Nutrition Examination Survey were used. Participants were asked to wear an accelerometer for 7 days. A blood sample was used to detect HIV and measure various biological parameters. Nineteen adults between 18 and 48 years of age had HIV and provided sufficient accelerometry data. Physical activity was not associated with CD4+ T cells. After adjustments, moderate-to-vigorous physical activity was inversely associated with systolic blood pressure (r = −0.44), fasting glucose (r = −0.78), and waist circumference (r = −0.45). These findings suggest that HIV-infected individuals are similar to those in the general population in that that their bodies are able to adapt to the many benefits associated with physical activity.

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