scholarly journals Loco-Regional BCGitis Revealing a HIV Infection in an Infant: A Case Report

2019 ◽  
Vol 11 (1) ◽  
pp. 13-16
Author(s):  
Ibtissam Khattou ◽  
Ouidad Louachama ◽  
Noureddine Rada ◽  
Ghizlane Draiss ◽  
Mohammed Bouskraoui

The BCG disease is a specific complication of the Bacille Calmette and Guerin (BCG) vaccine. It is often in the form of benign local BCGitis, however the BCGosis is a lethal disseminated disease that can occur in a patient with immunodeficiency. The prognosis depends on the immune status of the patient, and the quality of management. Therapeutic modalities are very controversial. In this article, the authors report a case of loco-regional BCGitis revealing an HIV infection.

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1399
Author(s):  
Domingos Sousa ◽  
Sérgio Antunes Silva ◽  
Catarina Jorge ◽  
Ana Isabel Rodrigues ◽  
Rita Martins Fernandes ◽  
...  

The Bacillus Calmette Guérin (BCG) vaccine was initially produced as a vaccine against tuberculosis. BCG is an attenuated live strain of Mycobacterium bovis and has been widely used as an immunotherapy over the last years in bladder cancer. We describe a case of a 61-year-old Caucasian male with previous bladder cancer, who had been treated for the last 15 months with instillation of BCG, admitted with 3-week evolution history of fever (38ºC), asthenia, anorexia and a weight loss of 6kg. The patient’s condition deteriorated leading to sepsis. A liver biopsy was performed showing granulomatous dispersed through all the parenchyma. Empirical therapy for M. bovis was started with good response. Even though it is rare, BCGitis must be ruled out in any patient submitted to immunotherapy with BCG and prompt therapy started if disseminated disease is present, which improves the outcome.


Biomedicine ◽  
2020 ◽  
Vol 39 (2) ◽  
pp. 372-376
Author(s):  
Ramadurai Jayapriya ◽  
T.N. Uma Maheswari ◽  
V Mukundh Chaithanya

Oral candidiasis is the most common opportunistic infection in human immunodeficiency virus infection. History, clinical examination, investigation and diagnosis of oral candidiasis is important for early diagnosis and treatment of HIV infection. Pseudomembranous candidiasis and erythematous candidiasis are associated with immune compromised state and so it is of prognostic significance like reduction in the viral load and CD4 positive T lymphocytes. In this case report, we present a case of a 34-year-old physically challenged asymptomatic male who came for replacement of mandibular anterior tooth who was diagnosed with all four common variants of oral candidiasis which predicted HIV infection. Quality of life of the patient was improved after the diagnosis and treatment.  


2020 ◽  
Vol 29 (4) ◽  
pp. 685-690
Author(s):  
C. S. Vanaja ◽  
Miriam Soni Abigail

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.


2015 ◽  
Vol 2 (2) ◽  
pp. 12-19 ◽  
Author(s):  
Sudharani P Naik ◽  
Rajesh Raman ◽  
S N Moth ◽  
Arun Kumar

Author(s):  
Ganapathi Rao ◽  
Vijay Kumar ◽  
Ashok Naikar ◽  
Chandrakanth Halli

A standard Ksharasutra is practiced in treatment of Bhagandara (fistula-in-ano) with high success rate and minimum recurrence rate. In previous research it was noted that Pittaja Prakruti patients sometime might cause more perianal irritation due to Apamarga Ksharasutra. So in this study Palasha Ksharasutra prepared in Arkaksheera was prepared by Palasha Kshara (Ash of Butea monosperma), Arka Ksheera (Calotropis gigantic) and turmeric powder (Curcuma longa). This Ksharasutra was prepared as per the API guidelines and preserved in air tight tube. A patient of Pittaja predominant Prakruti with fistula-in ano having two external opening at 6 and 7 O’ clock position of anus was treated with application of Ksharasutra. The Palasha Ksharasutra prepared in Arkaksheera was applied in these two opening under spinal anesthesia. Then Ksharasutra was changed by weekly interval under local xylocaine jelly 2%. The length of thread was measured weekly and noted in the case to assess the unit cutting time (UCT). The unit cutting time (UCT) of first thread was 7.5 days/cm and second one had UCT 6.8 days/cm. During the treatment patient was doing his job regularly without hampering the quality of life. After 2 months patient was free from all symptoms of fistula with normal scar and without any complications. This case study demonstrated the utility of Palasha Ksharasutra prepared in Arkaksheera in multiple fistula-in ano.


Author(s):  
Maristela Barbosa Portela,

Linear gingival erythema (LGE), formally referred as HIV-gingivitis, is the most common form of HIV-associated periodontal disease in HIV-infection. These lesions were recently evaluated as a possible form of erythematous oral candidosis, mainly caused by Candida albicans. Other species are also being associated such as C. tropicalis, C. stellatoidea, C. krusei, C. parapsilosis, C. glabrata and C. dubliniensis, that was identified in some HIV-infected subjects. This case report demonstrates the presence of typical LGE lesions in six HIV-infected children, also investigates the etiologic agent by microbiological exams and correlates this oral manifestation with patients’ systemic conditions. Microbiological analyses showed positive growth for Candida spp in all patients, all of whom had severe imunessupression. After antifungal medication, the regression of lesions could be note. The presence of LGE in pediatric patients with AIDS may indicate its feature as a predictive marker in progression of HIV-infection in children.


Author(s):  
Lorenzo Anelli ◽  
Alessia Di Nardo ◽  
Massimo Bonucci

Abstract Introduction A retrospective clinical study was performed to identify the characteristics of patients with lung cancer treated with integrative cancer treatment in addition to conventional medicine. Materials and Methods We reviewed medical records for lung cancer patients who visited a single integrative setting in Rome, Italy. A total of 57 patients were included, and the majority had advanced-stage cancer. All of them underwent integrative therapy with nutrition and phytotherapy indications. The diet was designed to reduce most of possible factors promoting cancer proliferation, inflammation, and obesity. Foods with anti-inflammatory, prebiotic, antioxidant, and anticancer properties had been chosen. Herbal supplements with known effects on lung cancer were prescribed. In particular, astragal, apigenine, fucosterol, polydatin, epigallocatechin gallate, cannabis, curcumin, and inositol were used. Furthermore, medical mushrooms and other substances were used to improve the immune system and to reduce chemotherapy side effects. Five key parameters have been evaluated for 2 years starting at the first surgery: nutritional status, immune status, discontinuation of therapy, quality of life, and prognosis of the disease. Results A relevant improvement in parameters relative to nutritional status, immune status, and quality of life has been observed after integrative therapy compared with the same parameters at the first medical visit before starting such approach. Conclusion The results suggest that integrative therapy may have benefits in patients with lung cancer. Even though there are limitations, the study suggests that integrative therapy could improve nutritional status and quality of life, with possible positive effect on overall survival.


Author(s):  
Alvaro Quincho-Lopez ◽  
Noah Kojima ◽  
John M. Nesemann ◽  
Rogger Verona-Rubio ◽  
Dina Carayhua-Perez

AbstractCryptococcosis is a fungal infection that is rarely reported in patients without human immunodeficiency virus (HIV) infection, especially when the central nervous system (CNS) or pulmonary system is not involved. We report a case of isolated colonic cryptococcosis without disseminated disease in a 64-year-old immunocompetent woman without HIV infection who presented with chronic diarrhea and no episodes of fever or weight loss. The diagnosis was based on histopathology examination. Furthermore, we performed a literature review showing that few reports have been published so far and in the case of colonic cryptococcal infection, the prognosis is favorable among HIV-uninfected patients.


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