scholarly journals Food and Aeroallergen Sensitization in IgE -Mediated Asthma in Egypt

2021 ◽  
Vol 15 (1) ◽  
pp. 52-58
Author(s):  
Abdellah H.K. Ali
Keyword(s):  
Specific Ige ◽  
Cross Sectional Study ◽  
House Dust Mites ◽  
Atopic Asthma ◽  
Food Allergens ◽  
Cross Sectional ◽  
Asthmatic Patients ◽  
Egyptian Patients ◽  
Ige Mediated ◽  
Effective Diagnosis

Purpose: Identifying the distribution of allergens is valuable to the effective diagnosis and treatment of allergic disease. So, our aim is to explore the sensitization of food and aeroallergens in Egyptian patients with atopic asthma. Methods: Cross-sectional study recruited 268 Egyptian patients with atopic asthma. Asthmatic patients were assessed by the enzyme allegro sorbent test (EAST) method for specific IgE to a panel of 19 common regional inhaled allergens and 15 food allergens. Results and Discussion: One hundred percent of the patients were sensitive to at least one allergen. Allergy to food allergens only was 2.9%; inhaled allergens only were 26.2% and both were70.9%. Fungi (62%) were the most frequent sensitizing aeroallergen amongst our asthmatic patients, followed by the pollen allergens (42.5%) and house dust mites (HDMs) (26%). Cows’ milk (30.5%) was the most frequent sensitizing food amongst our asthmatic patients, followed by eggs (22.4%) and fish (21.6%). Mono-sensitized patients accounted for 6.7% of all cases, while polysensitized was 93.3%. Moderate and severe asthma showed a significantly higher frequency of polysensitization compared to mild asthma. Conclusion: Fungi and cow's milk are the chief sensitizing allergens in Egyptian patients with atopic asthma. This study represents the first report of sensitization in atopic adult asthma using a large extract panel in Upper Egypt.

scholarly journals Asthma severity in relation to allergenic risk factors in childhood

2005 ◽  
Vol 133 (Suppl. 2) ◽  
pp. 101-104
Author(s):  
Snezana Zivanovic ◽  
Radmila Mileusnic-Milenovic ◽  
Maja Slavkovic-Jovanovic ◽  
Marija Conic
Keyword(s):  
Statistical Significance ◽  
Persistent Asthma ◽  
Asthma Severity ◽  
Specific Ige ◽  
Atopic Asthma ◽  
Dermatophagoides Farinae ◽  
Asthmatic Patients ◽  
Ige Mediated ◽  
Inhalant Allergens ◽  
Airborne Allergens

The majority of asthmatic patients are atopic - that is to say, they exhibit IgE-mediated sensitivity to common inhalant allergens. Exposure and sensitisation to allergens from the housedust mite has been established as an important risk factor in asthma in most parts of the world. The aim of our study was to assess total IgE and specific IgE on airborne allergens (Dermatophagoides pteronyssinus - DP, Dermatophagoides farinae - DF, mould, and grass pollen) in relation to asthma severity. The study involved 64 children with atopic asthma. Statistical significance was present between groups of intermittent and moderately persistent asthma for IgE and specific IgE on DP and moulds. In mild and moderate asthma, statistically significant differences were present for all parameters except for DF.

Prevalence of Food Allergy in Egyptian Patients complaining of food adverse events attending allergy clinic at Ain Shams University Hospitals

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Zeinab A Yousif ◽  
Manar F Mohammed ◽  
Dahab N Zakaraya
Keyword(s):  
Food Allergy ◽  
Adverse Events ◽  
Immune Reaction ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Allergy Clinic ◽  
University Hospitals ◽  
Cross Sectional ◽  
Egyptian Patients ◽  
Ige Mediated

Abstract Background Food allergy is defined as an immune reaction to proteins in the food and can be immunoglobulin (Ig)E-mediated or non–IgE-mediated. IgE-mediated food allergy is a worldwide health problem that affects millions of persons and numerous aspects of a person’s life. Allergic reactions secondary to food ingestion are responsible for a variety of symptoms involving the skin, gastrointestinal tract, and respiratory tract. While all other non-allergic food reactions are categorized as “food intolerance”. Aims to assess prevalence of Food allergy among Egyptian patients complaining of food adverse events attending Allergy clinic at Ain Shams University Hospital. Methods This was a randomized cross sectional study involving 200 patients complaining of food adverse events attending Allergy clinic at Ain Shams University Hospitals between the first of February 2019 till the end of January 2020, 90 patents had confirmed food allergy Results The Total patients who were presented to the Allergy outpatient clinic at Ain Shams University hospital between the first of February 2019 and the end of January 2020 were 200 patients presented complaining of food adverse events with the percentage (9.5%). Among the 200 patients presented complaining of food adverse events, there were 90 patients who were confirmed food allergy. Conclusion food allergy may be over estimated along patient with food adverse events.

scholarly journals Immunoglobulin-E Mediated Chlorhexidine Hypersensitivity among Healthcare Workers

2021 ◽  
Vol 5 (5) ◽  
pp. 1-11
Author(s):  
Alam SMJ
Keyword(s):  
Confidence Interval ◽  
Healthcare Workers ◽  
Immunoglobulin E ◽  
Wide Spectrum ◽  
Specific Ige ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Occupationally Exposed ◽  
Ige Mediated ◽  
Occupational Settings

Objective: With a wide spectrum antimicrobial activity that is not affected by body fluids and blood, chlorhexidine is a particularly useful disinfectant widely used in healthcare settings. Given the importance of disinfectant usage by healthcare workers to prevent nosocomial infections, particularly during the COVID-19 pandemic, this study aims to evaluate the prevalence of immunoglobulin E (IgE)-mediated sensitivity in healthcare workers. Methodology: A cross-sectional study was conducted through a questionnaire and immunoassay for chlorhexidine- specific IgE in healthcare workers in a large teaching hospital in London, UK. The prevalence of IgE-mediated chlorhexidine hypersensitivity was determined along with potential determinants. Results: With a 77.7% response rate, the study showed that 4 out of 233 participants were positive for chlorhexidine-specific IgE, with an overall prevalence of 1.72% (95% Confidence Interval: 0.05% to 3.39%). All the positive cases belonged to occupationally exposed healthcare workers. In this group, the prevalence rate was 2.82% (95% Confidence Interval: 0.1% to 5.54%). Conclusion: Chlorhexidine is a potential allergen and an under-reported cause of anaphylaxis in patient-care and occupational settings. The results suggest that chlorhexidine has a relatively safe profile for healthcare workers in occupational settings, but a higher prevalence of chlorhexidine hypersensitivity cannot be ruled out. Sensitized healthcare workers must be advised to avoid further exposure to prevent potentially serious IgE-mediated allergic symptoms. Further studies are recommended to determine if any change in disinfection guidelines and protocols is warranted.

scholarly journals Detection of Serum Allergen-Specific IgE in Atopic Dogs Tested in Northern Italy: Preliminary Study

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 358
Author(s):  
Morena Di Tommaso ◽  
Alessia Luciani ◽  
Paolo Emidio Crisi ◽  
Marica Beschi ◽  
Paolo Rosi ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Specific Ige ◽  
Elisa Test ◽  
Northern Italy ◽  
House Dust Mites ◽  
Indoor Allergens ◽  
Allergic Skin ◽  
Antibody Elisa ◽  
Ige Mediated ◽  
Indoor And Outdoor

Canine atopic dermatitis (CAD) is a pruritic allergic skin disease associated with IgE-mediated hypersensitivity. IgE is detected using Serum Allergen-Specific IgE test (SAT) in order to identify allergens. The present study aims to identify the environmental allergens in atopic dogs living in Northern Italy using SAT. The screening SAT (sSAT), using a monoclonal antibody cocktail-based ELISA to identify indoor and outdoor allergens, was performed. In all positive samples, an anti-IgE monoclonal antibody ELISA test was performed to extend panel of allergens. Out of 117 selected dogs, 69 were included in the study; 71% were positive and 29% were negative to sSAT. Among the 49 positive sSAT, 53% were positive for both indoor and outdoor, 38.8% only for indoor, and 8.2% only for outdoor allergens. This is the first study on the frequency of allergens involved in CAD in Italy using SAT. IgE hypersensitivity in atopic dogs of Northern Italy is usually associated with indoor allergens, primarily house dust mites. Among the outdoor allergens, an important role was played by Rumex acetosa. Polysensitization also commonly occurs. Therefore, since the numerous factors affect the IgE positivity in CAD, specific panels for geographical areas should be considered and re-evaluated at time intervals.

scholarly journals Shedding Light on the Direct and Indirect Impact of the COVID-19 Pandemic on the Lebanese Radiographers or Radiologic Technologists: A Crisis within Crises

Healthcare ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 362
Author(s):  
Rasha Itani ◽  
Mohammed Alnafea ◽  
Maya Tannoury ◽  
Souheil Hallit ◽  
Achraf Al Faraj
Keyword(s):  
Health And Safety ◽  
Cross Sectional Study ◽  
Knowledge Development ◽  
Sectional Study ◽  
Cross Sectional ◽  
Radiologic Technologists ◽  
Staff Members ◽  
Workplace Conditions ◽  
Novel Coronavirus ◽  
Effective Diagnosis

With the novel coronavirus disease 2019 (COVID-19) pandemic, the need for radiologic procedures is increasing for the effective diagnosis and follow-up of pulmonary diseases. There is an immense load on the radiographers’ shoulders to cope with all the challenges associated with the pandemic. However, amidst this crisis, Lebanese radiographers are also suffering from a socioeconomic crisis and record hyperinflation that have posed additional challenges. A cross-sectional study was conducted among registered Lebanese radiographers to assess the general, workplace conditions, health and safety, mental/psychologic, financial, and skill/knowledge development impacts. Despite applying an adapted safety protocol, institutions are neither providing free RT-PCR testing to their staff nor showing adequate support for infected staff members, thus causing distress about contracting the virus from the workplace. Aggravated by the deteriorating economic situation that affected the radiographers financially, they additionally suffer from severe occupational physical and mental burnout. Regardless of that, they used their free time during the lockdown for skill/knowledge development and have performed many recreational activities. This cross-sectional study highlighted the different ways the pandemic has impacted the radiographers: physically, psychologically, and financially. It aimed to shed light on what these frontline heroes are passing through in the midst of all these unprecedented crises.

scholarly journals Impact of Covid-19 on asthmatic patients in Western region in Saudi Arabia

2021 ◽  
Vol 20 (11) ◽  
Author(s):  
Abdulrhman Nasser Zaher AlGhamdi ◽  
Amal Mohammed Albaqami ◽  
Areej Mohammed Abdullah ◽  
Doha Abdulrahmman Alsukhayri ◽  
Hamad Albulrahman Alawi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Data Entry ◽  
Cross Sectional Study ◽  
Western Region ◽  
Poor Control ◽  
Key Words Asthma ◽  
Cross Sectional ◽  
Icu Admission ◽  
Asthmatic Patients ◽  
The Impact

Background: Respiratory symptoms are a characteristic feature present in covid-19 patients, and they usually range from mild to severe. Asthma is a chronic disease involving the airways that carry air in and out of the lungs. However, there is limited resources that discuss the relation between asthma and prevalence of COVID-19. Aims: Identify the impact of covid19 on asthmatic patients. Methodology: This is a descriptive cross-sectional study that was conducted to study the impact of COVID-19 on asthmatic patients, which was conducted using a prepared questionnaire which was distributed online among 300 patients with asthma. After collecting the data, MS Excel was used for data entry while SPSS version 24 was used for data analysis. Results: In this study, we were able to collect data from 311 asthmatic patients in response to our questionnaire. Most of the asthmatic patients were females (67.2%) with a ratio of females: males of 2:1. Moreover, most patients thought that they control their asthma well and only 13.5 % indicated that they had frequent emergency visits because of asthma. The prevalence of COVID-19 in asthmatic patients was 64.3 % where a third of patients needed to go to hospital because of their bad condition, 12.6 % needed to be hospitalized in ICU and 56.4 % needed oxygen. Moreover, severity of COVID-19 symptoms and outcomes are related to the control of asthma where better control of asthma was associated with better outcomes including lower need for ICU admission and oxygen need. Conclusion: Prevalence of COVID-19 in asthmatic patients was much higher than the general population especially in female patients aged between 31-40 years old. Moreover, COVID-19 had more severe outcomes in asthmatic patients including higher prevalence of ICU admission and oxygen need. Poorer outcomes of COVID-19 were associated with poor control of asthma. Key words: Asthma, Covid-19, Western Region, Saudi Arabia

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