scholarly journals A PROSPECTIVE STUDY ON QUALITY OF LIFE IN PATIENTS WITH ARTHRITIS

Author(s):  
Sathesh Kumar Sukumaran ◽  
Poojitha Devi G

<p>ABSTRACT<br />Objective: Patient counseling can scientifically improve the physical and mental symptoms of certain diseases that could be a relief to the patient.<br />Non-pharmacological approaches could be an alternative to the drug therapy. Health issues affecting the quality of life (QoL) are to be studied to<br />understand the patient’s physical, mental, emotional, and social functioning.<br />Methods: The present study involves prospective analysis of QoL in men and women with arthritis. The methodology involves the collection and<br />documentation of general information of the patient including personal history, family background, clinical findings, investigations, and medical illness<br />associated with arthritis. Further, the QoL is documented using a specific questionnaire designed to assess the impact of arthritis and their complications.<br />Results: It can be seen that there is no significant changes in the physical and mental component score (MCS) in between the type of arthritis, but<br />there is an extremely significant (p&lt;0.05) values were obtained when compared between pre- and post-counseling phases of physical and MCS.<br />Conclusion: Patients counseling plays a major role in the management of signs and symptoms among patients with arthritis. The non-pharmacological<br />method is also be used for the management of arthritis.<br />Keywords: Quality of life, Arthritis, Patient counseling, Questionnaire, Physical component score, Mental component score.</p>

Author(s):  
Shanmugapriya J ◽  
Sathesh Kumar S

  Objective: The objective of the study is to compare the quality of life (QoL) in both men and women with urinary calculi using SF-12 questionnaire and also to improve by patient education. Patient counseling can scientifically improve the physical and mental component of certain diseases that could be a relief to the patient. Non-pharmacological approaches could be an alternative to the drug therapy.Methods: The present study involves prospective study on QoL in patients with urinary calculi. The methodology involves the collection and documentation of general information of the patient including personal history, family background, clinical findings, investigations, and medical illness associated with urinary calculi. Further, quality is documented using SF-12 questionnaire designed to assess the impact of urinary calculi and their complications.Result: It can be seen that there is an extremely significant (p<0.0001) values were obtained when compared between pre- and post-counseling phases of physical and mental component scores (PCS and MCS). Patient’s PCS and MCS improved extremely significant in post-counseling.Conclusion: Patients counseling plays a major role in the management of signs and symptoms among patient with urinary calculi. Clinicians should be aware of the risk of impaired health-related QoL (HRQoL) in stone formers. A new and promising endpoint in the management of urolithiasis is improvement of HRQoL.


2010 ◽  
Vol 8 (4) ◽  
pp. 449-454
Author(s):  
Tomer T. Levin ◽  
John Riskind ◽  
Yuelin Li

AbstractObjective:Looming cognitive styles (LCS) bias the velocity of potential threats and have been implicated in anxiety and depression vulnerability. This study aims to explore their contribution to impaired quality of life (QOL), beyond that of depression and anxiety, in a cancer cohort.Method:In a cross-sectional design, an ambulatory chronic lymphocytic leukemia (CLL) cohort completed a psychological battery that included the Beck Depression and Anxiety Inventories, the SF-36 Health Survey, the Functional Assessment of Chronic Illness Therapy (FACT), the Looming Cognitive Style Questionnaire (LCSQ), and the Looming Cancer measure.Results:The Looming Cancer measure correlated significtly with overall QOL (FACT-G, p = 0.005). This effect was largely due to the contribution of emotional QOL (Mental Component Score: SF-36, p = 0.001; FACT-emotional, p = 0.001) and functional QOL (FACT-functional, p = 0.001). Looming, unlike anxiety and depression, did not correlate with a worse physical QOL (Physical Component Score: SF-36, FACT-physical). Looming did not impact on social QOL. Hierarchical regression analysis showed that looming predicted 5.4% of the varience on the FACT-emotional, 5.1% on the Mental Component Score (SF-36), and 9.3% on the mental health subscale (SF-36), above and beyond the varience predicted by a constellation of psychosocial factors (including age, marital status, education, income) and the combined effect of depression and anxietySignificance of results:LCS predicts worse emotional and functional QOL, above and beyond the contribution of anxiety, depression, and other psycho-social variables. This suggests that it makes a unique contribution to a worse QOL. Nevertheless, the looming construct still remains primarily a research tool in psycho-oncology at this time.


Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Ya Su ◽  
Michiko Yuki ◽  
Kengo Hirayama

Background and Purpose: Post-stroke fatigue (PSF) is a frequent complication that worsens the patient’s rehabilitation outcomes and quality of life. Many studies have demonstrated a robust relationship between PSF and post-stroke depression and insomnia. However, sarcopenia was usually not taken into account. As stroke survivors manage and adapt to their functional limitations, the rhythms, and routines of life poststroke changes. At 1 month after discharge home, frustration is a common response to these changes. Therefore, this study was aimed to investigate the impact of post-stroke fatigue from the acute phase to the first month after discharge and assess the possible contributions of sarcopenia to discharged PSF. Design: A single-center prospective observational study. Participants: 94 patients with acute stroke were recruited between May 2019 and July 2020. Methods: Clinical and stroke characteristics were collected from electronic medical records. Pre and post-stroke factors were collected by questionnaire. The main outcomes were included fatigue, depression, insomnia, sarcopenia, and health-related quality of life (QOL) was assessed at admission, and one month after discharged home. Fatigue was measured using the Fatigue Assessment Scale. Sarcopenia was measured using the SARC-F questionnaire. Results: The prevalence of PSF was 25.5% at admission and 29.8% at one month after discharged home. PSF at admission was associated with fatigue (p<0.01), insomnia (p<0.01), higher SARC-F scores (p=0.026), and lower QOL scores [Physical Component Score (p=0.029) and Mental Component Score (p=0.006)] at one month after discharged home. Conclusions: There is a really beginning that transition for stroke patients at discharge from hospital to home. In this study, PSF during hospitalization can affect sleep status and QOL after discharge, and which is consistent with previous studies. It is worth noting that patients with PSF at admission had higher SARC-F scores after discharged home. Muscle wasting is a common complication accompanying stroke, which may not only contribute to physical function reduction but also psychological function, it deserves more attention in clinical practice and scientific research.


Pituitary ◽  
2021 ◽  
Author(s):  
Muhammad Fahad Arshad ◽  
Oluwafunto Ogunleye ◽  
Richard Ross ◽  
Miguel Debono

Abstract Purpose There is no consensus on quality of life (QOL) in patients with acromegaly requiring medical treatment after surgery compared with those achieving remission by surgery alone. Methods QuaLAT is a cross-sectional study comparing QOL in surgery-only treated acromegaly patients versus those requiring medical treatment post-surgery. Patients attending clinics were identified and divided into—Group 1: patients who had surgery only and were in biochemical remission, Group 2: all patients on medical treatment post-surgery, Group 3: patients from Group 2 with biochemical control. Participants were asked to fill three questionnaires; Acromegaly Quality of Life Questionnaire (ACROQOL), 36-Item Short Form Survey (SF36), and Fatigue Severity Scale (FSS). Results There were 32 patients in Group 1 and 25 in Group 2. There was no difference in QOL scores between groups 1 and 2, as measured by ACROQOL (mean difference [MD] = − 2.5, 95% CI − 16.6 to 11.6; p = 0.72), SF36v2 [Physical component score (PCS) MD = − 4.9, 95% CI − 10.9 to 1.2; p = 0.12; mental component score MD = − 3.0, 95% CI − 10.5 to 4.4; p = 0.44], or FSS (MD = − 0.004, 95% CI − 1.14 to 1.33; p = 0.1). Comparison between groups 1 and 3 however showed that PCS (and 3 subdomains) was significantly better in group 3 (MD = − 8.3, 95% CI − 14.8 to -1.8; p = 0.01). All three QOL scores were lower when compared with healthy controls. Conclusions Medical treatment not only achieves a QOL comparable to surgery, it may also be associated with better QOL in physical subdomains. When compared with healthy controls, QOL remains worse in treated acromegaly patients compared to controls.


Open Heart ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. e001569
Author(s):  
Fredrike Blokzijl ◽  
Frederik Keus ◽  
Saskia Houterman ◽  
Willem Dieperink ◽  
Iwan C C van der Horst ◽  
...  

ObjectiveThis study aimed to explore the influence of coronary artery bypass grafting (CABG) on both postoperative cognitive dysfunction and quality of life (QoL) and the association between the two patient-related outcomes.MethodsIn a prospective, observational cohort study, patients with elective, isolated CABG were included. Cognitive function was assessed using the Cogstate computerised cognitive test battery preoperatively, 3 days and 6 months after surgery. QoL was measured preoperatively and at 6 months using the RAND-36 questionnaire including the Physical Component Score (PCS) and the Mental Component Score (MCS). Regression analysis, with adjustment for confounders, was used to evaluate the association between postoperative cognitive dysfunction and QoL.ResultsA total of 142 patients were included in the study. Evidence of persistent cognitive dysfunction was observed in 33% of patients after 6 months. At 6 months, the PCS had improved in 59% and decreased in 21% of patients, and the MCS increased in 49% and decreased in 29%. Postoperative cognitive changes were not associated with QoL scores.ConclusionsPostoperative cognitive dysfunction and decreased QoL are common 6 months after surgery, although cognitive function and QoL were found to have improved in many patients at 6 months of follow-up. Impaired cognitive function is not associated with impaired QoL at 6 months.Trial registration numberNCT03774342.


Author(s):  
Sathesh Kumar Sukumaran ◽  
Ayswarya P

ABSTRACTObjective: To study the impact of patient counseling on medication adherence and quality of life (QOL) in epileptic patients and to assess the factorsaffecting medication adherence.Methods: This study is a prospective observational study involving 100 patients with an age limit of 8-60 years and those taking Antiepilepticdrugs for at least 3 months. The study population received patient counseling during their first visit. The impact of patient counseling on QOL andmedication adherence was assessed using self-reported questionnaire QOLIE-31 and MMAS-8 between the first visit and the second visit. Statisticalanalysis (Paired t-test and Paired Chi-square test) was performed to analyze the impact of patient counseling on QOL and medication adherence inepileptic patients.Results: A total of 100 patients were included in the study. After providing patient counseling, it was observed that there was a statistically significant(p<0.05) improvement in all domains of QOLIE-31 and MMAS-8 scores. Before counseling, mean overall T-score of QOLIE-31 was 44.08±2.07whichwas changed to 49.14±1.27 after patient counseling with a mean change of 5.06 in overall T-score. In the case of medication adherence, beforecounseling 77% subjects were nonadherent to therapy, after counseling it was reduced to 41%. The common reasons for medication adherence wereforgetfulness, unawareness, therapy related, and economics related. Out of which forgetfulness along with unawareness was the major one.Conclusion: The study described that patient counseling plays a major role in improving QOL and medication adherence.Keywords: QOLIE-31, MMAS-8, Epilepsy, Antiepileptic drugs, Patient counseling.


2018 ◽  
Vol 29 (04) ◽  
pp. 371-377 ◽  
Author(s):  
Stefanie Witt ◽  
Michaela Dellenmark-Blom ◽  
Jens Dingemann ◽  
Carmen Dingemann ◽  
Benno M. Ure ◽  
...  

Introduction For parents of chronically ill children, the experiences of caregiving are challenged by increased demands and restrictions imposed by their child's disease. Therefore, this study aims to investigate the quality of life (QoL) in parents of children born with esophageal atresia (EA) and to explore associated factors. Materials and Methods Parents of children (2–17 years) with EA recruited from two German pediatric hospitals participated in this cross-sectional study about QoL in EA. Data on QoL, sociodemographic, and clinical characteristics were collected from parents and children. Parental QoL was assessed using the Short-Form 8 questionnaire, containing eight dimensions aggregated to a mental and physical health summary score which was compared with German representative population norms. Results Forty-nine families (47 mothers and 40 fathers) participated in the study. Compared with German population norms, both mothers and fathers showed significantly lower mental component score (MCS) but no differences in physical component score (PCS). Within the study sample, parents of younger children (2–7 years), severe EA, or high school/kindergarten absence had lower MCSs compared with those with older, less severe, and less absent children. Parental female gender was associated with lower MCS as well as lower family income. Conclusion Parents of children with EA reported lower mental health compared with the general population, especially mothers, and parents of young children, with severe EA, and a frequent school/kindergarten absence. This shows that parents may experience substantial emotional burden and highlights the need for psychosocial support for EA parents, especially in the first years.


2008 ◽  
Vol 26 (16) ◽  
pp. 2754-2760 ◽  
Author(s):  
Carrie A. Karvonen-Gutierrez ◽  
David L. Ronis ◽  
Karen E. Fowler ◽  
Jeffrey E. Terrell ◽  
Stephen B. Gruber ◽  
...  

Purpose The purpose of this study was to examine whether quality of life (QOL) scores predict survival among patients with head and neck cancer, controlling for demographic, health behavior, and clinical variables. Patients and Methods A self-administered questionnaire was given to 495 patients being treated for head and neck cancer while they were waiting to be seen for a clinic appointment. Data collected from the survey included demographics, health behaviors, and QOL as measured by Short Form-36 (SF-36) physical and mental component scores and the Head and Neck QOL scores. Clinical measures were collected by chart abstraction. Kaplan-Meier plots and univariate and multivariate Cox proportional hazards models were used to determine the association between QOL scores and survival time. Results After controlling for age, time since diagnosis, marital status, education, tumor site and stage, comorbidities, and smoking, the SF-36 physical component score and three of the four Head and Neck QOL scales (pain, eating, and speech domains) were associated with survival. Controlling for the same variables, the SF-36 mental component score and the emotional domain of the Head and Neck QOL were not associated with survival. Conclusion QOL instruments may be valuable screening tools to identify patients who are at high risk for poor survival. Those with low QOL scores could be followed more closely, with the potential to identify recurrence earlier and perform salvage treatments, thereby possibly improving survival for this group of patients.


2017 ◽  
Vol 48 (7) ◽  
pp. 1111-1118 ◽  
Author(s):  
E. Morton ◽  
G. Murray ◽  
E. E. Michalak ◽  
R. W. Lam ◽  
S. Beaulieu ◽  
...  

AbstractBackgroundAlthough quality of life (QoL) is receiving increasing attention in bipolar disorder (BD) research and practice, little is known about its naturalistic trajectory. The dual aims of this study were to prospectively investigate: (a) the trajectory of QoL under guideline-driven treatment and (b) the dynamic relationship between mood symptoms and QoL.MethodsIn total, 362 patients with BD receiving guideline-driven treatment were prospectively followed at 3-month intervals for up to 5 years. Mental (Mental Component Score – MCS) and physical (Physical Component Score – PCS) QoL were measured using the self-report SF-36. Clinician-rated symptom data were recorded for mania and depression. Multilevel modelling was used to analyse MCS and PCS over time, QoL trajectories predicted by time-lagged symptoms, and symptom trajectories predicted by time-lagged QoL.ResultsMCS exhibited a positive trajectory, while PCS worsened over time. Investigation of temporal relationships between QoL and symptoms suggested bidirectional effects: earlier depressive symptoms were negatively associated with mental QoL, and earlier manic symptoms were negatively associated with physical QoL. Importantly, earlier MCS and PCS were both negatively associated with downstream symptoms of mania and depression.ConclusionsThe present investigation illustrates real-world outcomes for QoL under guideline-driven BD treatment: improvements in mental QoL and decrements in physical QoL were observed. The data permitted investigation of dynamic interactions between QoL and symptoms, generating novel evidence for bidirectional effects and encouraging further research into this important interplay. Investigation of relevant time-varying covariates (e.g. medications) was beyond scope. Future research should investigate possible determinants of QoL and the interplay between symptoms and wellbeing/satisfaction-centric measures of QoL.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Denis Vinnikov ◽  
Aizhan Raushanova ◽  
Zhanna Romanova ◽  
Zhangir Tulekov

Abstract Background Health-related quality of life (HRQL) in the general population of Kazakhstan has never been characterized. We constructed this population-based study of the largest city in Kazakhstan, Almaty with the aim to quantitatively assess HRQL and ascertain whether occupation and lifestyle are associated with HRQL in this population. Methods In a random sample (N = 1500) of general population in Almaty (median age 49 (interquartile range 28) years, 50% women), we collected data on demographics, socioeconomic status, lifestyle, lifetime occupational history and general HRQL using SF-8 instrument. The association of demographic and occupational predictors with HRQL was tested in multiple regression models. Results No occupational associations were found for physical component score in the models adjusted for age, sex, income, cigarette and waterpipe smoking, electronic cigarette use, physical activity, alcohol and exposure to secondhand smoke. Ever being a manager (β − 1.63 (95% confidence interval (CI) − 2.92; − 0.34)), a welder (β − 5.11 (95% CI − 8.77; − 1.46)) and a secretary (β − 5.06 (95% CI − 8.56; − 1.56)) for one year or more was associated with poorer mental component score in the models adjusted for age, sex, income, cigarette smoking, physical activity and each other. Age, income and physical activity were independent predictors of both physical and mental components. Conclusions Occupational history is associated with HRQL in the general population in Almaty, Kazakhstan, but the mechanism explaining this association should be further elucidated.


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