scholarly journals THE UTILIZATION OF VISUAL BASIC.NET APPLICATION FOR DETERMINATION OF INDIVIDUAL DRUG DOSAGES IN DIABETIC PATIENTS OF CHRONIC RENAL DISORDER COMPLICATIONS

2018 ◽  
Vol 11 (13) ◽  
pp. 234
Author(s):  
Ari Usman ◽  
Nilsya Febrika Zebua
Keyword(s):  
Creatinine Clearance ◽  
Medical Records ◽  
Diabetes Complications ◽  
Diabetic Patients ◽  
Dose Calculations ◽  
Inclusion Criteria ◽  
Renal Disorder ◽  
Descriptive Research ◽  
Patients With Diabetes

  Objective: This research aims to apply the Visual Basic.Net (VB.NET) of individual dose calculations based on the formula of pharmacokinetics for diabetic patients of chronic renal disorder complication in Dr. Pirngadi Hospital because the dosage administered was not based on the patient’s creatinine clearance.Methods: This descriptive research was conducted using a simulated creatinine cleavage calculation using VB.NET programming language applications with variable patient data, the value of creatinine, the name of drug, and dosage.Results: This study obtained data about the use of drugs 40 patients who met the inclusion criteria of 320 medical records of diabetic patients, there are 6 types of drugs that are not in accordance with the dose based on the calculation of creatinine clearance are ceftriaxone(18 of 18 cases), furosemide (19 of 19 cases), ciprofloxacin (2 of 8 cases), ranitidine (4 of 24 cases), metformin (2 of 7 cases), and captopril (16 of 16 cases).Conclusions: This research aims to apply the VB.NET is it able to apply individual doses for patients with diabetes complications of renal failure have not been applied in accordance with creatinine clearance calculations at this hospitalwhere this work is difficult to do.

scholarly journals The Correlation between Clinical and Demographic Parameters and Sickness Absence in Diabetic Employees

Healthcare ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1309
Author(s):  
Oren Zack ◽  
Irena Golob ◽  
Gabriel Chodick ◽  
Idan Perluk ◽  
Rachel Raanan ◽  
...  
Keyword(s):  
Medical Records ◽  
Pearson Correlation ◽  
Severity Of Illness ◽  
Diabetic Patients ◽  
Telephone Interviews ◽  
Public Sector Employees ◽  
Patients With Diabetes ◽  
Absence From Work ◽  
Control Study ◽  
Hba1c Levels

Objectives: Diabetes mellitus is one of the most significant and prevalent chronic diseases. Individuals with diabetes can still encounter substantial difficulties in finding and keeping their job because of their condition. The purpose of this study was to examine the scope of diabetes-related absence from work and its relationship with variables such as type of employer, workload, the severity of illness, and type of treatment. Materials and Methods: We conducted a case-control study, including 220 diabetic patients and 230 controls. Information regarding absence from work was obtained by reviewing medical records, and general patient information was retrieved by conducting telephone interviews. Results: Patients with diabetes had, annually, more days of absence than non-diabetic patients (8.5 vs. 2.7, respectively p and lt; 0.001). Among diabetic patients, public-sector employees were absent more than private-sector employees (9.0 vs. 7.2 days, respectively, p and lt; 0.05). A positive correlation was found between workload (measured by stamina) and absence (Pearson correlation = 0.098, p = 0.04). Concerning the clinical variables, we found that employees suffering from diabetic complications exhibited higher absence rates (15.5 vs. 5.7 days, respectively, p and lt; 0.003). Parameters like HbA1c levels, patient age, disease duration, and type of treatment did not differ significantly amongst the groups with regards to absence rates. Conclusions: The main variables affecting absence from work were not medical but rather sociodemographic: education, workload, and type of employer. The results of this study reinforce the perception that well-controlled diabetic employees can be combined in most types of occupations without fear of increased absence from work.

Screening for microalbuminuria in patients with diabetes mellitus: frozen storage of urine samples decreases their albumin content.

1989 ◽  
Vol 35 (2) ◽  
pp. 308-310 ◽  
Author(s):  
L D Elving ◽  
J A Bakkeren ◽  
M J Jansen ◽  
C M de Kat Angelino ◽  
E de Nobel ◽  
...  
Keyword(s):  
Frozen Storage ◽  
Urine Samples ◽  
Diabetic Patients ◽  
Albumin Concentration ◽  
Low Concentrations ◽  
Albumin Content ◽  
Patients With Diabetes ◽  
The Difference ◽  
Urinary Albumin Concentration

Abstract The influence of storage on urinary albumin concentration was prospectively studied with use of overnight urine specimens (Albustix negative) from 73 diabetic patients. From each urine sample four aliquots were taken. One was stored at 4 degrees C and assayed within two weeks, the other three were stored at -20 degrees C and assayed within two weeks and after two and six months. Albumin concentration was measured with laser immunonephelometry. The detection limit, 1 mg/L, suffices for the screening of diabetic patients for microalbuminuria. After storage for two and six months at -20 degrees C, significantly lower albumin concentrations were found. The difference was mainly caused by lower concentrations found in urine samples in which a precipitate had formed, which was the case in 22 and 25 samples, respectively. Thus, freezing of urine samples for determination of low concentrations of albumin may yield falsely low results. Urine samples are best stored at 4 degrees C and assayed within two weeks.

scholarly journals Relationship between adherence to anti-diabetic medication and depression among patients with diabetes mellitus in three selected Chinese hospitals

2021 ◽  
Vol 20 (1) ◽  
pp. 183-190
Author(s):  
Haidong Luo ◽  
Yin Lin ◽  
Jia Li ◽  
Weiguo Xu
Keyword(s):  
Diabetes Mellitus ◽  
Sampling Technique ◽  
Mood Disturbance ◽  
Diabetic Patients ◽  
Inclusion Criteria ◽  
Duration Of Illness ◽  
Long Duration ◽  
Patients With Diabetes ◽  
High Level ◽  
The Relationship

Purpose: To determine the relationship between adherence to anti-diabetic medication and depression among patients with diabetes mellitus in three hospitals in Chinese.Methods: This research utilized a quantitative and descriptive design, and included 200 diabetic patients who fulfilled the inclusion criteria for recruitment through a convenient sampling technique. The study applied Beck’s depression inventory II scale for assessment of depression, and a questionnaire for adherence to anti-diabetic medication.Results: A total of 64 (32 %) participants had diabetes for 6 to 10 years. There was a high level of adherence to anti-diabetic medication in 96 patients (48 %); 74 participants (37 %) had moderate adherence to anti-diabetic medication, while 30 patients (15 %) had low adherence. A majority of the patients (181, 90.5 %) had no depression. Six (6) patients (3 %) had mild mood disturbance, 2 patients (1 %) had borderline clinical depression, while 11patients (5.5 %) experienced moderate depression.Adherence to anti-diabetic medication was not associated with depression (p = 0.068). However, depression was associated with age ˃ 50 years (p = 0.041), female sex (p = 0.043), long duration of illness (> 5-years) (p = 0.048), and presence of one or more comorbidities (p = 0.049).Conclusion: There was no association between adherence to anti-diabetic medication and depression among diabetic patients. Keywords: Adherence to anti-diabetic medication, Beck’s depression inventory II, Depression, Diabetes mellitus

scholarly journals Fructosamine 3-Kinase and Glyoxalase I Polymorphisms and Their Association With Soluble RAGE and Adhesion Molecules in Diabetes

2014 ◽  
pp. S283-S291 ◽  
Author(s):  
J. ŠKRHA ◽  
A. MURAVSKÁ ◽  
M. FLEKAČ ◽  
E. HOROVÁ ◽  
J. NOVÁK ◽  
...  
Keyword(s):  
Adhesion Molecules ◽  
Diabetes Complications ◽  
Diabetic Patients ◽  
Glyoxalase I ◽  
Advanced Glycation ◽  
Soluble Rage ◽  
Glycation End Products ◽  
Patients With Diabetes ◽  
Relationship Of

Advanced glycation end-products (AGEs) are key players in pathogenesis of long-term vascular diabetes complications. Several enzymes such as fructosamine 3-kinase (FN3K) and glyoxalase I (GLO I) are crucial in preventing glycation processes. The aim of our study was to evaluate an association of FN3K (rs1056534, rs3848403) and GLO1 rs4746 polymorphisms with parameters of endothelial dysfunction and soluble receptor for AGEs (sRAGE) in 595 diabetic and non-diabetic subjects. Genotypic and allelic frequencies of mentioned polymorphisms did not differ between subgroups. In diabetic patients significant differences were observed in sRAGE concentrations according to their rs1056534 and rs3848403 genotype. While GG and CG genotypes of rs1056534 with mutated G allele were associated with significant decrease of sRAGE (GG: 1055±458 and CG: 983±363 vs. CC: 1796±987 ng/l, p<0.0001), in rs3848403 polymorphism TT genotype with mutated T allele was related with significant sRAGE increase (TT: 1365±852 vs. CT: 1016±401 and CC: 1087±508 ng/l, p=0.05). Significant differences in adhesion molecules were observed in genotype subgroups of GLO1 rs4746 polymorphism. In conclusion, this is the first study describing significant relationship of FN3K (rs1056534) and (rs3848403) polymorphisms with concentration of sRAGE in patients with diabetes.

PROFIL KADAR GULA DARAH PASIEN DIABATES MELITUS TIPE 2 RAWAT JALAN YANG MENDAPAT TERAPI KOMBINASI GLIKLAZID-METFORMIN DI RS. DR. SARDJITO YOGYAKARTA

2019 ◽  
Vol 3 (2) ◽  
pp. 19
Author(s):  
Ririn Puspadewi
Keyword(s):  
Blood Glucose ◽  
Combination Therapy ◽  
Medical Records ◽  
Diabetic Patients ◽  
Receive Combination Therapy ◽  
Type 2 Diabetic Patients ◽  
Glucose Content ◽  
Patients With Diabetes ◽  
Blood Glucose Concentrations

The purpose of this research is to find out how the fluctuation of outpatients’ blood-glucose concentrations of type 2 diabetic patients who receive combination therapy of the oral antihiperglicemic drugs (gliclazide-metformin) in DR. Sardjito Hospital. The research was conducted using an analysis-descriptive design employing a number of medical-records of patients with diabetes mellitus to collect the glucose content data. Data derived from the medical records is the data of each patient’s blood-glucose content during six months, beginning  from March to August 2002. The results give that profile of the glucose concentrations in fasting condition and 2 hours postprandial condition who recieve combination therapy of the oral antidiabetic (gliclazide-metformin) can reach out for normal concentration.

STATUS NUTRISI PASIEN GAGAL GINJAL KRONIS DENGAN DIABETES MELLITUS DAN NON-DIABETES MELLITUS

2016 ◽  
Vol 5 (2) ◽  
pp. 92-98
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Medical Records ◽  
Descriptive Research ◽  
Measuring Devices ◽  
Laboratory Results ◽  
Patients With Diabetes ◽  
Test Result

Background:Malnutrition is a common problem in chronic renal failure (CRF) patients with or without Diabetes Mellitus (DM). An assessment of nutritional status in CRF patients is encouraged to see the level of its severity. The general parameters for assessing nutritional status are serum albumin and hemoglobin. Objective:The objective of this research was to investigate the differences on thenutritional status of CRF patients with Diabetes Mellitus (DM) compared to those without DM at PKU Muhammadiyah Hospital Yogyakarta. Methods:This was a comparative descriptive research applying accidental sampling and was conducted for 6 months (June-November 2014). The main measuring devices were patients’ medical records and laboratory results of albumin and hemoglobin levels. Sampleof this study consisted of 30 respondents. Independent t-test was applied to analyze the differences of albumin and hemoglobin levels in both groups. Result:The test result showed that the albumin (p=0.917) and hemoglobin levels (p=0.168) of CRF patients without DM and that of CRF patients with DM were not significantly different. Conclusion:CRF patients with and without DM had low level of albumin and hemoglobin. Nurses shouldbe more careful in regulating fluidbalance to reduce pulmonary edema. Keywords:Chronic Renal Failure (CRF), diabetes mellitus(DM), albumin, hemoglobin

scholarly journals Gender Effect on the Relation between Diabetes and Hospitalization for Heart Failure

2011 ◽  
Vol 120 (01) ◽  
pp. 51-55 ◽  
Author(s):  
C. Seghieri ◽  
P. Francesconi ◽  
S. Cipriani ◽  
M. Rapanà ◽  
R. Anichini ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Heart Failure ◽  
Medical Records ◽  
Gender Effect ◽  
Diabetic Patients ◽  
Male And Female ◽  
Increased Risk ◽  
Patients With Diabetes ◽  
The One ◽  
Number Of Individuals

AbstractCardiovascular risk among diabetic patients is at least twice as much the one for non-diabetic individuals and even greater when diabetic women are considered. Heart failure (HF) is a common unfavorable outcome of cardiovascular disease in diabetes. However, since the comparison among sexes of heart failure prevalence in diabetic patients remains limited, this study is aimed at expanding the information about this point.We have evaluated the association between diabetes and HF by reviewing the medical records of all subjects discharged from the Internal Medicine and Cardiology Units of all hospitals in the Tuscany region, Italy, during the period January 2002 through December 2008. In particular we sought concomitance of ICD-9-CM codes for diabetes and HF.Patients discharged by Internal Medicine were on average older, more represented by women, and had a lesser number of individuals coded as diabetic (p<0.05 for all). Relative risk for HF (95% CI) was significantly higher in patients with diabetes, irrespective of gender 1.39 (1.36–1.41) in males; 1.40 (1.37–1.42) in females. When the diabetes-HF association was analyzed according to decades of age, a “horse-shoe” pattern was apparent with an increased risk in 40–59 years old in female patients discharged by Internal Medicine.Although there is not a difference in the overall HF risk between hospitalized male and female diabetic patients, women have an excess risk at perimenopausal age.

scholarly journals Determination of Glycosylated Haemoglobin in Normal, Newborn and Diabetic Saudi Arabs

1987 ◽  
Vol 24 (3) ◽  
pp. 279-282 ◽  
Author(s):  
A I Alayash ◽  
A Dafallah ◽  
H Al-Husayni ◽  
A K Al-Ali ◽  
A Al-Qourain ◽  
...  
Keyword(s):  
Thiobarbituric Acid ◽  
Mean Value ◽  
Glycosylated Haemoglobin ◽  
Diabetic Patients ◽  
Adult Males ◽  
Glycosylated Haemoglobin Level ◽  
Patients With Diabetes ◽  
The Mean ◽  
Normal Adults

Colorimetric determinations of glycosylated haemoglobin by the thiobarbituric acid method were carried out in normal adults ( n = 142), newly born infants of healthy mothers ( n = 81), and in a group of patients with diabetes mellitus ( n = 124). The glycosylated haemoglobin level in normal adult males was 4·9%, which is close to that reported for other populations. No correlation was found between age and the levels of glycosylated haemoglobin in males over 10 years old. However, the mean value for glycosylated haemoglobin in cord blood was 4·1%, significantly different from that of adults. The range values for glycosylated haemoglobin in diabetic patients was 7–19%. The mean value for glycosylated haemoglobin was 10·9%, similar to that established in other diabetic populations. Results of colorimetric determinations of glycosylated haemoglobin in the Saudi population compare well with other ethnic groups and, therefore, suggest no ethnic differences in glycosylated haemoglobin levels.

scholarly journals Diagnostic value of cystatin C for the early diagnosis of diabetic nephropathy

2021 ◽  
pp. 79-85
Author(s):  
V. N. Vasilkova ◽  
I. Yu. Pchelin ◽  
E. P. Naumenka ◽  
Ya. A. Borovets ◽  
Yu. I. Yarets ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Early Diagnosis ◽  
Cystatin C ◽  
Diagnostic Value ◽  
Diabetic Patients ◽  
Risk Of Mortality ◽  
Patients With Diabetes ◽  
Reliable Marker

Objective: to assess the clinical significance of cystatin C in the early diagnosis of diabetic nephropathy.Materials and methods. We examined 449 patients with type 1 and type 2 diabetes mellitusolder than 25 years. The laboratory examination of the patients included the measurement of cystatin, creatinine in the blood serum, GFR calculation according to the CKD-EPI equation, and the determination of albuminuria levels.Results. The role of cystatin C as a reliable marker of diabetic nephropathy has been demonstrated: the level of cystatin C ≥ 0.72 mg/L with sensitivity of 90.8 %, specificity of 88.9 %, was associated with a decline of renal function in the diabetic patients (ROC AUC = 0.951).Conclusion. The determination of the level of cystatin C, alone or in conjunction with creatinine, will help to more accurately diagnose GFR and assess the risk of mortality and renal complications in patients with diabetes mellitus.

scholarly journals STATUS NUTRISI PASIEN GAGAL GINJAL KRONIS DENGAN DIABETES MELLITUS DAN NON-DIABETES MELLITUS

2019 ◽  
Vol 5 (2) ◽  
pp. 92-98
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Medical Records ◽  
Descriptive Research ◽  
Measuring Devices ◽  
Laboratory Results ◽  
Patients With Diabetes ◽  
Test Result

Background:Malnutrition is a common problem in chronic renal failure (CRF) patients with or without Diabetes Mellitus (DM). An assessment of nutritional status in CRF patients is encouraged to see the level of its severity. The general parameters for assessing nutritional status are serum albumin and hemoglobin. Objective:The objective of this research was to investigate the differences on thenutritional status of CRF patients with Diabetes Mellitus (DM) compared to those without DM at PKU Muhammadiyah Hospital Yogyakarta. Methods:This was a comparative descriptive research applying accidental sampling and was conducted for 6 months (June-November 2014). The main measuring devices were patients’ medical records and laboratory results of albumin and hemoglobin levels. Sampleof this study consisted of 30 respondents. Independent t-test was applied to analyze the differences of albumin and hemoglobin levels in both groups. Result:The test result showed that the albumin (p=0.917) and hemoglobin levels (p=0.168) of CRF patients without DM and that of CRF patients with DM were not significantly different. Conclusion:CRF patients with and without DM had low level of albumin and hemoglobin. Nurses shouldbe more careful in regulating fluidbalance to reduce pulmonary edema. Keywords: Chronic Renal Failure (CRF), diabetes mellitus(DM), albumin, hemoglobin

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