The Correlation between Clinical and Demographic Parameters and Sickness Absence in Diabetic Employees

Objectives: Diabetes mellitus is one of the most significant and prevalent chronic diseases. Individuals with diabetes can still encounter substantial difficulties in finding and keeping their job because of their condition. The purpose of this study was to examine the scope of diabetes-related absence from work and its relationship with variables such as type of employer, workload, the severity of illness, and type of treatment. Materials and Methods: We conducted a case-control study, including 220 diabetic patients and 230 controls. Information regarding absence from work was obtained by reviewing medical records, and general patient information was retrieved by conducting telephone interviews. Results: Patients with diabetes had, annually, more days of absence than non-diabetic patients (8.5 vs. 2.7, respectively p and lt; 0.001). Among diabetic patients, public-sector employees were absent more than private-sector employees (9.0 vs. 7.2 days, respectively, p and lt; 0.05). A positive correlation was found between workload (measured by stamina) and absence (Pearson correlation = 0.098, p = 0.04). Concerning the clinical variables, we found that employees suffering from diabetic complications exhibited higher absence rates (15.5 vs. 5.7 days, respectively, p and lt; 0.003). Parameters like HbA1c levels, patient age, disease duration, and type of treatment did not differ significantly amongst the groups with regards to absence rates. Conclusions: The main variables affecting absence from work were not medical but rather sociodemographic: education, workload, and type of employer. The results of this study reinforce the perception that well-controlled diabetic employees can be combined in most types of occupations without fear of increased absence from work.

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Effect of Different Factors on Glycosylated Hemoglobin (HbA1c) Levels Among Diabetes Mellitus Patients

10.53350/pjmhs2115123513 ◽

2021 ◽

Vol 15 (12) ◽

pp. 3513-3515

Author(s):

Bader Alsuwayt

Keyword(s):

Diabetes Mellitus ◽

Glycated Hemoglobin ◽

Glycosylated Hemoglobin ◽

Diabetic Patients ◽

Study Results ◽

Patients With Diabetes ◽

Insulin Use ◽

Low Rate ◽

Statin Use ◽

Hba1c Levels

Aim: To describe the rate of the controlled level of glycosylated hemoglobin (HbA1c) among diabetes mellitus patients in Dammam city, Kingdom of Saudi Arabia (KSA). To assess the association between the status of HbA1c and the different patient-related factors namely: insulin use, metformin, dyslipidemia, and statin use. Methods: This cross-sectional study was performed at Security Forces Hospital, Dammam, KSA, between November 2020 and February 2021. A sample of two hundred known diabetic patients who were regularly followed up at the outpatient department (OPD) was selected randomly for the current study. Results: A very low rate (24%) of controlled HbA1C levels in patients with diabetes (type 1 DM and type 2 DM), The data showed that 85 % of all participants in our study are T2DM patients, while only 15% are T1DM patients, Our data showed that patients with dyslipidemia, hypothyroidism, or hypertension have a high level of uncontrolled HbA1C levels. Surprisingly, both dyslipidemia and statin use were predictors of uncontrolled HbA1C, Unexpectedly, non-metformin use has a protective effect toward controlling HbA1C, While insulin use is a strong predictor of uncontrolled HbA1C (OD 5.20). Conclusion: A low rate of controlled glycated hemoglobin (HbA1c) level among patients with diabetes (T1DM and T2DM) in our sample urges the need for immediate intervention to investigate and improve the current findings. Further investigations are needed to fully explain the high rate of uncontrolled HbA1c among insulin, metformin and statins users. Keywords: Glycated hemoglobin, HbA1c, Diabetes mellitus, Statins, Metformin.

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THE UTILIZATION OF VISUAL BASIC.NET APPLICATION FOR DETERMINATION OF INDIVIDUAL DRUG DOSAGES IN DIABETIC PATIENTS OF CHRONIC RENAL DISORDER COMPLICATIONS

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2018.v11s1.26616 ◽

2018 ◽

Vol 11 (13) ◽

pp. 234

Author(s):

Ari Usman ◽

Nilsya Febrika Zebua

Keyword(s):

Creatinine Clearance ◽

Medical Records ◽

Diabetes Complications ◽

Diabetic Patients ◽

Dose Calculations ◽

Inclusion Criteria ◽

Renal Disorder ◽

Descriptive Research ◽

Patients With Diabetes

Objective: This research aims to apply the Visual Basic.Net (VB.NET) of individual dose calculations based on the formula of pharmacokinetics for diabetic patients of chronic renal disorder complication in Dr. Pirngadi Hospital because the dosage administered was not based on the patient’s creatinine clearance.Methods: This descriptive research was conducted using a simulated creatinine cleavage calculation using VB.NET programming language applications with variable patient data, the value of creatinine, the name of drug, and dosage.Results: This study obtained data about the use of drugs 40 patients who met the inclusion criteria of 320 medical records of diabetic patients, there are 6 types of drugs that are not in accordance with the dose based on the calculation of creatinine clearance are ceftriaxone(18 of 18 cases), furosemide (19 of 19 cases), ciprofloxacin (2 of 8 cases), ranitidine (4 of 24 cases), metformin (2 of 7 cases), and captopril (16 of 16 cases).Conclusions: This research aims to apply the VB.NET is it able to apply individual doses for patients with diabetes complications of renal failure have not been applied in accordance with creatinine clearance calculations at this hospitalwhere this work is difficult to do.

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The Association of Depression and the Cardiovascular Risk Factors of Blood Pressure, HbA1c, and Body Mass Index among Patients with Diabetes: Results from the Translating Research into Action for Diabetes Study

International Journal of Endocrinology ◽

10.1155/2012/747460 ◽

2012 ◽

Vol 2012 ◽

pp. 1-6 ◽

Cited By ~ 7

Author(s):

Lindsay B. Kimbro ◽

W. Neil Steers ◽

Carol M. Mangione ◽

O. Kenrik Duru ◽

Susan L. Ettner

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Cardiovascular Health ◽

Diabetic Patients ◽

Cross Sectional ◽

Patients With Diabetes ◽

Patient Health ◽

Hba1c Levels

Diabetic patients are nearly three times as likely to have depression as their nondiabetic counterparts. Patients with diabetes are already at risk for poor cardiovascular health. Using cross-sectional data from the translating research into action for diabetes (TRIAD) study, the authors tested the association of depression with cardiovascular risk factors in diabetic patients. Depression was measured using the patient health questionnaire (PHQ8). Patients who scored greater than 9 on the PHQ8 were classified as depressed and were compared with those who were not depressed(n=2,341). Depressed patients did not have significantly different blood pressure levels than those who were not depressed. However, those who were depressed had higher HbA1c levels than those who were not depressed(P<0.01)and higher BMIs than those who were not depressed(P<0.01). These results indicate that depressed diabetic patients are at greater risk of having poor control of cardiovascular risk factors and suggest that depression screening should be a standard practice among this patient group.

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EVALUATION OF THE LONG-TERM EFFECTS OF EXPOSURE TO GREENSPACE ON TYPE 2 DIABETIC PATIENTS: CASE STUDY – TEHRAN, IRAN

ISPRS Annals of Photogrammetry Remote Sensing and Spatial Information Sciences ◽

10.5194/isprs-annals-iv-2-w5-471-2019 ◽

2019 ◽

Vol IV-2/W5 ◽

pp. 471-477

Author(s):

A. Esmaeilzadeh ◽

M. R. Delavar ◽

E. Nasli-Esfahani

Keyword(s):

Satellite Imagery ◽

Urban Policy ◽

Pearson Correlation ◽

Environmental Parameters ◽

Diabetic Patients ◽

Long Term Effects ◽

Type 2 Diabetic Patients ◽

Hba1c Levels

<p><strong>Abstract.</strong> Development of information technology and expansion of geospatial information systems have realized the planning managers and urban policy-makers’ wishes in making more informed decisions about urban management. At the same time, population growth and the provision of its health should be considered as one of the most important and remarkable issues for many researchers and medical specialists. So, in recent years there have been an increasing number of researches related to the study of effective factors such as environment parameters on the people’s health. In previous research, the long-term exposure effects of environmental parameters such as greenspace and air pollution on people’s health have been mostly ignored or access to reliable data has not been accomplished. The aim of this research is to study how the long-term exposure to greenspace surrounding the type 2 diabetes mellitus (T2DM) affects the average values of four years glycolized hemoglobin (HbA1c) levels. Moreover, in order to study the effects of the data type on reliability of the results, land-use data base (LDB) and satellite imagery have been employed. Pearson product and regression model have been used in this research for correlation and buffer analyse to calculate the degree of exposure of T2DM persons to greenspace. According to the results, negative correlation between long-term exposure to greenspace and the average values of four years HbA1c levels becomes statistically significant. Pearson correlation coefficients for the LDB (r&thinsp;=&thinsp;&minus;0.366, p&thinsp;=&thinsp;0.001) and satellite imagery (r&thinsp;=&thinsp;&minus;0.276, p&thinsp;=&thinsp;0.006) at 250-meter buffer from diabetic patients’ habitat is significant at 99% confidence level.</p>

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Risk factors for eye complications in patients with diabetes mellitus: development and progression

Eastern Mediterranean Health Journal ◽

10.26719/2000.6.2-3.313 ◽

2000 ◽

Vol 6 (2-3) ◽

pp. 313-325

Author(s):

M. El Shazly ◽

M. Zeid ◽

A. Osman

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Diabetic Retinopathy ◽

Case Control Study ◽

Case Control ◽

Diabetic Patients ◽

Patients With Diabetes ◽

Control Study

A multicentre case-control study was conducted to identify and quantify risk factors that may influence the development and progression of diabetic retinopathy. A total of 200 diabetic patients with nonproliferative retinopathy were compared with 400 diabetic patients without any eye complications with regard to the development of diabetic retinopathy. They were also compared with 200 diabetic patients with major eye complications to study the progression of diabetic eye complications. Results showed that the progression of diabetic eye complications was preventable since all the variables significantly affecting the process of progression, except type of diabetes, were avoidable

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Split-Thickness Skin Grafts to the Foot and Ankle of Diabetic Patients

Journal of the American Podiatric Medical Association ◽

10.7547/15-200 ◽

2017 ◽

Vol 107 (5) ◽

pp. 365-368 ◽

Cited By ~ 6

Author(s):

Kyle Sanniec ◽

Tea Nguyen ◽

Suzanne van Asten ◽

Javier La Fontaine ◽

Lawrence A. Lavery

Keyword(s):

Skin Graft ◽

Hba1c Level ◽

Wound Closure ◽

Current Evidence ◽

Diabetic Patients ◽

Skin Grafts ◽

Thickness Skin ◽

Patients With Diabetes ◽

Early Wound ◽

Hba1c Levels

Background: There is an increased prevalence of foot ulceration in patients with diabetes, leading to hospitalization. Early wound closure is necessary to prevent further infections and, ultimately, lower-limb amputations. There is no current evidence stating that an elevated preoperative hemoglobin A1c (HbA1c) level is a contraindication to skin grafting. The purpose of this review was to determine whether elevated HbA1c levels are a contraindication to the application of skin grafts in diabetic patients. Methods: A retrospective review was performed of 53 consecutive patients who underwent split-thickness skin graft application to the lower extremity between January 1, 2012, and December 31, 2015. A uniform surgical technique was used across all of the patients. A comparison of HbA1c levels between failed and healed skin grafts was reviewed. Results: Of 43 surgical sites (41 patients) that met the inclusion criteria, 27 healed with greater than 90% graft take and 16 had a skin graft that failed. There was no statistically significant difference in HbA1c levels in the group that healed a skin graft compared with the group in which skin graft failed to adhere. Conclusions: Preliminary data suggest that an elevated HbA1c level is not a contraindication to application of a skin graft. The benefits of early wound closure outweigh the risks of skin graft application in patients with diabetes.

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Study of the Association Between Diabetes and Helicobacter Pylori Infection in a Tunisian Population

European Journal of Medical and Health Sciences ◽

10.24018/ejmed.2020.2.4.423 ◽

2020 ◽

Vol 2 (4) ◽

Author(s):

Chaima Jemai ◽

Rim Rachdi ◽

Sonia Bellamine ◽

Lamia Bouallegue ◽

Faika Ben Mami

Keyword(s):

Helicobacter Pylori ◽

Medical Records ◽

Tunisian Population ◽

Control Group ◽

Patients With Diabetes ◽

And Gender ◽

H Pylori ◽

Control Study

Introduction: The association between diabetes and Helicobacter Pylori (H. Pylori) infection remains controversial in the literature. The aim of our study was to search an association between diabetes and H. Pylori infection. Methods: This is a case-control study carried out in 2017 over 3 months (September-October-November), collecting 120 patients with dyspepsia, matched for age and gender into two groups: a group of 77 patients with diabetes, and a group of control cases made of 43 non-diabetics. Diabetes was defined according to the American Diabetes Association (ADA) of 2017. Clinical, biological, endoscopic and anatomopathological data were collected from medical records. Results: The average age of the patients was 50±2,1 year. The sex ratio was 0.51. 34.2% (n=41) patients were male. Diabetes was type 2 in the majority of cases (88.31%) and type 1 in 11.68% only. H. Pylori infection was more prevalent in diabetics (19.48%, 11.63%, p=0.27). H. Pylori infection was more prevalent in type 1 diabetics (44.44%, 16.18%, p= 0.04). The frequency of upper endoscopic lesions in diabetics and controls was 70.13% and 74.42%, respectively. Chronic gastritis, gastric atrophy, and intestinal metaplasia were found in 61%, 3.9% and 2.6% of the cases in the group of diabetics and 62.79%, 6.98% and 4.65% respectively in the control group (p= not significant (NS)). Conclusion: Our study shows the absence of a significant association between diabetes and H. Pylori infection, as well as the absence of endoscopic and histological specificities of this infection in patients with diabetes.

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Association of Glutathione–S-Transferase (GSTP1) Genetic Polymorphism in Iraqi Patients with Diabetes Mellitus Type2

Baghdad Science Journal ◽

10.21123/bsj.13.1.36-43 ◽

2016 ◽

Vol 13 (1) ◽

pp. 36-43

Author(s):

Baghdad Science Journal

Keyword(s):

Diabetes Mellitus ◽

Active Role ◽

Control Group ◽

Diabetic Patients ◽

Glutathione S Transferase ◽

The People ◽

Patients With Diabetes ◽

Glutathione S Transferases ◽

Polymerase Chain ◽

Control Study

Glutathione S-transferases (GSTs) are enzymes that included, in a more range of detoxifying reactions by conjugation of glutathione, to electrophilic material. Polymorphisms n the genes that responsible of GSTs affect, the function of the GSTs. GSTs play an active role in protection of cell against oxidative stress mechanism. Polymorphisms of GSTP1 at codon 105 amino acids forms GSTP1 important site for bind of hydrophobic electrophiles and the substitution of Ile/Val affect substrate specially catalytic activity of the enzyme and may correlate with reach to different diseases in human like diabetes mellitus type2 disease. Correlation between these polymorphisms and changes in the parameters file of diabetic patients has also been found, therefore, the results variation considerably among the studies; therefore, these control study was designed to leading to detecting know, as there are no studies on this performed in the people of Iraq. The polymerase chain reaction-restriction fragment length polymorphism was used to study GSTP1genetic polymorphism in 60 T2DM patients and 50 healthy individuals. Our results showed that presence of the GSTP1 heterozygous mutant allele Ile/Val was more common in subjects with T2DM than in the control group (40.00% and 32.00%, respectively; p = 0.01), as well as the found of the homozygous mutant of GSTP1 allele Val/Val was common in T2DM patient and not found in the control group (3.33% and 0.00%, respectively; p = 0.001).GSTP1 genotypes do not have an effect on blood lipids after infection with diabetes mellitus. Agarose gels used to determined genotypes according to the bands were that appeared in electrophoresis of gel.

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Misleading HbA1c Measurement in Diabetic Patients with Hemoglobin Variants

Medical Sciences ◽

10.3390/medsci9020043 ◽

2021 ◽

Vol 9 (2) ◽

pp. 43

Author(s):

Manthana Mitchai ◽

Nattakarn Suwansaksri ◽

Suphakdee Seanseeha ◽

Jindamanee Saenboonsiri ◽

Putthichai Kraitree ◽

...

Keyword(s):

Capillary Electrophoresis ◽

Beta Thalassemia ◽

Diabetic Patients ◽

Strong Positive Correlation ◽

High Prevalence ◽

Patients With Diabetes ◽

Abnormal Hemoglobin ◽

Hemoglobin Variants ◽

Hba1c Measurement ◽

Hba1c Levels

Background and Objectives: Hemoglobin A1c (HbA1c) is widely used for the monitoring and management of diabetes mellitus. The aim of this study is to investigate the influence of hemoglobin (Hb) variants on the measurement of HbA1c. Materials and Methods: HbA1c levels of 845 blood samples obtained from diabetic patients with various hemoglobin types were measured using a turbidimetric inhibition immunoassay and capillary electrophoresis. Results: Of 845 patients with diabetes, 65.7% (555/845) have the normal hemoglobin type (A2A) and 34.3% (290/845) have various abnormal hemoglobin types, including heterozygous HbE 30.2% (255/845), homozygous HbE 1.9 % (16/845), Hb Constant Spring (CS) trait 1.4% (12/845), CSEA Bart’s 0.2% (2/845), and beta-thalassemia trait 0.6% (5/845). In most of the patients with diabetes, HbA1c levels determined by two different methods, inhibition immunoassay and capillary electrophoresis, gave strong positive correlation (R = 0.901, P < 0.001), except for those with homozygous HbE (N = 16) and CSEA Bart’s (N = 2). In all 18 patients with homozygous HbE and CSEA Bart’s, the HbA1c was undetectable by capillary electrophoresis, meaning that their estimated average glucose was undeterminable, although their HbA1c levels could be measured using an inhibition immunoassay. The discrepancy of HbA1c results obtained from two different methods is noted in patients without HbA. Conclusions: We have demonstrated the erroneous nature of HbA1c measurement in patients with hemoglobin variants, especially in those without HbA expression. Therefore, in the population with a high prevalence of hemoglobinopathies, hemoglobin typing should be considered as basic information prior to HbA1c measurement.

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PROFIL KADAR GULA DARAH PASIEN DIABATES MELITUS TIPE 2 RAWAT JALAN YANG MENDAPAT TERAPI KOMBINASI GLIKLAZID-METFORMIN DI RS. DR. SARDJITO YOGYAKARTA

Sains & Teknologi ◽

10.24123/jst.v3i2.2282 ◽

2019 ◽

Vol 3 (2) ◽

pp. 19

Author(s):

Ririn Puspadewi

Keyword(s):

Blood Glucose ◽

Combination Therapy ◽

Medical Records ◽

Diabetic Patients ◽

Receive Combination Therapy ◽

Type 2 Diabetic Patients ◽

Glucose Content ◽

Patients With Diabetes ◽

Blood Glucose Concentrations

The purpose of this research is to find out how the fluctuation of outpatients’ blood-glucose concentrations of type 2 diabetic patients who receive combination therapy of the oral antihiperglicemic drugs (gliclazide-metformin) in DR. Sardjito Hospital. The research was conducted using an analysis-descriptive design employing a number of medical-records of patients with diabetes mellitus to collect the glucose content data. Data derived from the medical records is the data of each patient’s blood-glucose content during six months, beginning from March to August 2002. The results give that profile of the glucose concentrations in fasting condition and 2 hours postprandial condition who recieve combination therapy of the oral antidiabetic (gliclazide-metformin) can reach out for normal concentration.

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