The age and gender effect on the association of sleep insufficiency with hypertension among adults in Greece

2021 ◽  
Author(s):  
Dimitrios Tsiptsios ◽  
Anestis Matziridis ◽  
Andreas Ouranidis ◽  
Andreas S Triantafyllis ◽  
Aikaterini Terzoudi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Behavioral Interventions ◽  
Sleep Disturbances ◽  
Age Groups ◽  
The Elderly ◽  
Short Sleep Duration ◽  
Males And Females ◽  
And Gender ◽  
The Relationship ◽  
Gender Specific

Background: We aimed to investigate the relationship between sleep characteristics with hypertension using self-reported questionnaires. Material & methods: A total of 957 adults were classified into three groups (short [<6 h], normal [6–8 h] and long [>8 h] sleepers). Hypertension was defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg or use of antihypertensive medication at the time of interview. Results: Overall prevalence of hypertension was 34.3%. Association between short sleep duration and hypertension that was age-specific, present only among younger and middle aged individuals and sparing the elderly, but not gender-specific, as no discrepancies existed between males and females in all age groups, was evident. Conclusion: This study promotes early pharmacological or cognitive behavioral interventions on sleep disturbances in order to reduce hypertension burden.

Age group and gender-wise comparison of obesity indices in subjects of Varanasi

2020 ◽  
Vol 64 ◽  
pp. 109-117
Author(s):  
Kumar Sarvottam ◽  
Prabhat Ranjan ◽  
Umashree Yadav
Keyword(s):  
Body Fat ◽  
Central Obesity ◽  
Age Groups ◽  
Age Group ◽  
Specific Distribution ◽  
Males And Females ◽  
And Gender ◽  
Obesity Indices ◽  
Relationship Of ◽  
The Relationship

Objectives: Deposition of body fat may differ in different age groups and gender-wise differences are also likely. The present study aims to evaluate age- and gender-wise differences in obesity parameters in healthy subjects of both genders of Varanasi. Materials and Methods: Anthropometric measurements were performed in 346 subjects reported in health check-up camp. Parameters were compared between each age group for males and females separately as well as gender-wise comparison for each age group was also performed. Regression analysis was performed to observe the relationship of age with obesity parameters and body mass index (BMI) with other parameters of obesity. Results: Both males and females had central obesity with males having higher waist circumference (WC) than females (P = 0.002) while females had higher body fat (fat %) (P = 0.000). Obesity indices of males of age group of 18–29 years were lesser as compared to other age groups. Obesity indices of female subjects were comparable in 18–39 years of age. Age group of 30–39 and 50–59 years males had higher WC than females (P = 0.002, 0.016, respectively) while fat % of females in each age group were significantly higher than males of corresponding age groups. Positive correlation of age with obesity parameters and BMI with WC and fat % was observed. Conclusion: Gender-wise differences in BMI, WC, WHtR and fat % tend to increase with age, indicative of increase in adiposity and central obesity with progressing age. Males in general have higher WC than females but lesser fat %. Gender differences in obesity may show age group specific variations. Findings of the study may be useful for identifying age specific distribution of obesity indices in males and females.

Projected future risk of leukemia and brain tumors from unnecessary brain CT scans: a multi-center study in Iran

2020 ◽  
Author(s):  
A. Asgari ◽  
A.A. Parach ◽  
F. Bouzarjomehri ◽  
F. Shirani-Takabi ◽  
A.H. Mehrparvar ◽  
...  
Keyword(s):  
Brain Cancer ◽  
Age Groups ◽  
Young Patients ◽  
Ct Scans ◽  
Brain Ct ◽  
Males And Females ◽  
And Gender ◽  
Multi Center Study ◽  
Gender Groups ◽  
Probability Of Cancer

Introduction: Computer Tomography (CT) scans can deliver a relatively high radiation dose to the patient, therefore radiation protection for this modality is paramount. The present study determined the frequency of no abnormality detected (NAD) brain CT scans and probability of cancer induction in different age groups and genders. Methods: In this study, brain CT reports were used to identify any findings as abnormality detected (AD) and others as NAD. Then probability of future leukemia and brain cancer was estimated for different age and gender groups. Results: On average, in 65% of the cases the results were NAD (56% and 76% among males and females, respectively). Among children, 79% of the reports were NAD. The total number of projected brain cancers was 1.8 and 1.3 for males and females, respectively. The number of projected leukemia cases was 0.75 and 0.7 for males and females, respectively. For pediatric patients, brain CT scans can lead to leukemia cases about 4.5 times more often than adults. Conclusion: Brain CT scans can lead to additional cases of brain cancer and leukemia. A significant fraction of brain CTs were NAD (non-pathologic) and could practically be replaced by other radiation-free imaging modalities, especially in pediatric and young patients.

scholarly journals Differential Influence of Age on the Relationship between Genetic Mismatch and A(H1N1)pdm09 Vaccine Effectiveness

Viruses ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 619
Author(s):  
Lirong Cao ◽  
Shi Zhao ◽  
Jingzhi Lou ◽  
Hong Zheng ◽  
Renee W. Y. Chan ◽  
...  
Keyword(s):  
Age Groups ◽  
The Elderly ◽  
Vaccine Effectiveness ◽  
Amino Acid Mutation ◽  
Epidemic Season ◽  
Vaccine Component ◽  
Linear Relationships ◽  
The Difference ◽  
Middle Aged Adults ◽  
The Relationship

Assessment of influenza vaccine effectiveness (VE) and identification of relevant influencing factors are the current priorities for optimizing vaccines to reduce the impacts of influenza. To date, how the difference between epidemic strains and vaccine strains at genetic scale affects age-specific vaccine performance remains ambiguous. This study investigated the association between genetic mismatch on hemagglutinin and neuraminidase genes and A(H1N1)pdm09 VE in different age groups with a novel computational approach. We found significant linear relationships between VE and genetic mismatch in children, young adults, and middle-aged adults. In the children’s group, each 3-key amino acid mutation was associated with an average of 10% decrease in vaccine effectiveness in a given epidemic season, and genetic mismatch exerted no influence on VE for the elderly group. We demonstrated that present vaccines were most effective for children, while protection for the elderly was reduced and indifferent to vaccine component updates. Modeling such relationships is practical to inform timely evaluation of VE in different groups of populations during mass vaccination and may inform age-specific vaccination regimens.

Trends in suicide rates of the elderly in Austria, 1970–2004: an analysis of changes in terms of age groups, suicide methods and gender

2007 ◽  
Vol 22 (5) ◽  
pp. 438-444 ◽  
Author(s):  
Nestor D. Kapusta ◽  
Elmar Etzersdorfer ◽  
Gernot Sonneck
Keyword(s):  
Age Groups ◽  
The Elderly ◽  
Suicide Methods ◽  
Suicide Rates ◽  
And Gender

Two Types of Anesthesia and Hemodynamic Changes in Patients Over 60 Years of Age Who Need Artificial Femoral Head Replacement: A Retrospective Cohort Study

2021 ◽  
Author(s):  
Weiqi Ke ◽  
Yuting WANG ◽  
Xukeng GUO ◽  
Ronghua HUANG ◽  
Xiangdong ZHANG ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Femoral Head ◽  
Elderly Patients ◽  
The Elderly ◽  
Hemodynamic Changes ◽  
Medical College ◽  
Replacement Surgery ◽  
Elder Patients ◽  
Significant Difference ◽  
And Gender

Abstract Background:Artificial femoral head replacement is one of the most effective methods for treatment of severe diseases of femoral joint in the elderly. The ideal anesthetic effect is one of the key elements for the success of the operation because it brings fast recovery. However, the multiple comorbidities of the elder patients make them too weak to tolerate the hemodynamic changes after anesthesia. In this case, the most suitable anesthesia method for patients undergoing femoral head replacement surgery is of great significance.Objective:To compare the post-anesthetic hemodynamic changes between combined lumbar plexus and sciatic nerve block(CLPSB) and combined spinal and epidural anesthesia(CSEA) in elderly patients undergoing unilateral artificial femoral head replacement.Methods:We reviewed records of the patients who aged over 60 years old (age 62-103 years) and received unilateral artificial femoral head replacement between January 2015 and December 2020 in the first affiliated hospital of Shantou University Medical College. After adjustment according to the inclusion criteria, 477 patients were included and divided into CLPSB group (n=90) and CSEA group (n=387). The primary outcome was comparison of the hemodynamic changes after anesthesia, including the systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and heart rate (HR). The second outcome was the comparison of the vasopressor used during the surgery.Results:We established three models to compare the two anesthesia methods on hemodynamic changes. Crude model included all variates for analysis, while model I adjusted age and gender. Model II adjusted other comorbidities in addition to model I. All three models exhibit that changes of MAP (∆MAP) after CSEA were higher than that after CLPSB(β= 6.88, 95% CI: 4.33 - 9.42, P < 0.0001), with significant difference, which indicated that CSEA causes higher fluctuation of MAP. Concurrently, the use of vasopressors increased by 137% (OR=2.37, 95%CI: 1.24-4.53, P=0.0091) in the CSEA group, which is statistically significant. However, the changes of HR (∆HR) between the CLPSB and CSEA was not significant(β= 0.50, 95% CI: 1.62 - 2.62, P = 0.6427). Conclusions:Both CLPSB and CSEA are ideal anesthesia methods for patients receiving femoral head eplacement, though CLPSB is more suitable for elderly patients with advanced hemodynamic stability.

scholarly journals Refined Multiscale Fuzzy Entropy to Analyse Post-Exercise Cardiovascular Response in Older Adults With Orthostatic Intolerance

Entropy ◽  
2018 ◽  
Vol 20 (11) ◽  
pp. 860 ◽  
Author(s):  
Marcos Hortelano ◽  
Richard Reilly ◽  
Francisco Castells ◽  
Raquel Cervigón
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Orthostatic Intolerance ◽  
Cardiovascular Response ◽  
Recovery Period ◽  
The Elderly ◽  
Fuzzy Entropy ◽  
Post Exercise ◽  
And Gender ◽  
Risk Factors For Falls

Orthostatic intolerance syndrome occurs when the autonomic nervous system is incapacitated and fails to respond to the demands associated with the upright position. Assessing this syndrome among the elderly population is important in order to prevent falls. However, this problem is still challenging. The goal of this work was to determine the relationship between orthostatic intolerance (OI) and the cardiovascular response to exercise from the analysis of heart rate and blood pressure. More specifically, the behavior of these cardiovascular variables was evaluated in terms of refined composite multiscale fuzzy entropy (RCMFE), measured at different scales. The dataset was composed by 65 older subjects, 44.6% (n = 29) were OI symptomatic and 55.4% (n = 36) were not. Insignificant differences were found in age and gender between symptomatic and asymptomatic OI participants. When heart rate was evaluated, higher differences between groups were observed during the recovery period immediately after exercise. With respect to the blood pressure and other hemodynamic parameters, most significant results were obtained in the post-exercise stage. In any case, the symptomatic OI group exhibited higher irregularity in the measured parameters, as higher RCMFE levels in all time scales were obtained. This information could be very helpful for a better understanding of cardiovascular instability, as well as to recognize risk factors for falls and impairment of functional status.

scholarly journals The Relationship between Nutritional Status, Sleep Duration, Stress Level with Blood Pressure of Nurse Night Shift in the Hospital: Cohort Study

2019 ◽  
Vol 4 (1) ◽  
pp. 55
Author(s):  
Salmawati Salmawati ◽  
Ari Natalia Probandari ◽  
Sapja Anantanyu
Keyword(s):  
Blood Pressure ◽  
At Risk ◽  
Nutritional Status ◽  
Sleep Duration ◽  
Stress Level ◽  
Night Shift ◽  
Anthropometric Measurement ◽  
Short Sleep Duration ◽  
Stress Levels ◽  
The Relationship

Objective: Hypertension as a cardiovascular disease occurs due to an uncontrolled increase in blood pressure. Night shift nurses with more overweight, short sleep duration, and excessive stress levels are at risk of increase blood pressure. This study aims to analyze how the relationship between obesity, nutritional status, sleep duration and stress level influence the blood pressure of the night shift nurses.Materials and methods: The subjects in this study were night shift nurses in four hospitals. The dependent variable was blood pressure and the independent variables were nutritional status, sleep duration, and stress levels. This study was an observational analysis with a perspective cohort design in which the subjects were 312 night shift nurses. Nutritional status were identified from Body Mass Index (BMI) through anthropometric measurement, sleep duration by looking at average hours of sleep during the night service, stress levels through the Perceived Stress Scale (PSS-10) questionnaire. Blood pressure was measured using a mercury sphygmomanometer. Data were analyzed by Chi-square test and Logistic Regression.Results and Discussion: There was a significant relationship between nutritional status, sleep duration, and stress levels with blood pressure. The results of the multivariate analysis showed that the shift nurses with overweight (obesity) nutritional status are at a risk of having disorder 1.97 times, the shift nurses with sleep duration < 6 hours are at risk of having disorder 3.78 times and shift nurses with intermediate stress level at risk of having disorder 2.08 times with enhancement blood pressure.Conclusion: There is a relationship between nutritional status, sleep duration and stress level with blood pressure. Sleep duration mostly influences the blood pressure.International Journal of Human and Health Sciences Vol. 04 No. 01 January’20 Page : 55-59

P5728Association of systolic blood pressure and cardiovascular outcomes at different age groups in the healthy general population: a nationwide prospective cohort study

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M H Jung ◽  
S H Ihm ◽  
S J An ◽  
S W Yi
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Age Groups ◽  
The Elderly ◽  
Cardiovascular Outcomes ◽  
Stroke Mortality ◽  
Linear Association ◽  
Hazard Ratios ◽  
Individualized Approach ◽  
Cvd Mortality

Abstract Background Uncertainties remain regarding the effect of blood pressure on various cardiovascular outcomes in different age groups. Purpose We aimed to identify 1) whether a systolic blood pressure (SBP) of 130–139 mm Hg elevates cardiovascular disease (CVD) mortality and 2) whether SBP shows a linear association with cause-specific CVD mortality in all age groups among individuals without known hypertension and CVD. Methods We used the Korean National Health Insurance sample data (n=429,220). Participants were categorized into three groups by age (40–59, 60–69, and 70–80 years). Results A positive and graded association was generally observed between SBP and overall and cause-specific CVD mortality regardless of age, except for ischemic heart disease (IHD) mortality in those aged 70–80 years. Among those aged 70–80, the hazard ratios (HRs) (95% CIs) for overall CVD mortality were 1.08 (0.92–1.28), 1.14 (0.97–1.34), and 1.34 (1.14–1.58) for SBP values of 120–129, 130–139, and 140–149 mm Hg, respectively, compared to SBP <120 mm Hg. For total stroke mortality, the corresponding HRs were 1.29 (1.02–1.64), 1.37 (1.09–1.72), and 1.52 (1.20–1.93), while for IHD mortality, the corresponding HRs were 0.90 (0.64–1.26), 0.86 (0.62–1.19), and 1.29 (0.93–1.78). Nonlinear associations were significant for IHD (Fig 1). Figure 1 Conclusion In the elderly Korean population, SBPs of 130–139 mm Hg elevated total stroke mortality, but not IHD mortality, compared to normal BP, and a linear association was not observed for IHD mortality in the range <140 mm Hg. Regarding an appropriate diagnostic cutoff for hypertension, an individualized approach considering each person's organ susceptibility is needed for the elderly population. Acknowledgement/Funding None

Sleep disturbances in adults with frailty and sarcopenia

2020 ◽  
Vol 21 (2) ◽  
pp. 89-107
Author(s):  
Reona Chiba ◽  
Yuki Ohashi ◽  
Akiko Ozaki
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Sleep Quality ◽  
Sleep Disturbances ◽  
Short Sleep Duration ◽  
Night Time ◽  
Content Type ◽  
Age Related ◽  
Increased Risk ◽  
The Relationship

Purpose Several epidemiological studies have reported an age-related increase in the prevalence of sleep disturbances. This study aims to investigate the relationship between sleep and sarcopenia/frailty in older adults and clarify issues that remain to be addressed in future studies. Design/methodology/approach PubMed was searched for relevant studies with the following keywords in the title: “sleep” and “sarcopenia” or “sleep” and “frailty.” A total of 15 studies published in English between 1998 and 2018 were reviewed. Findings Among the four studies that examined the relationship between sarcopenia and sleep, two reported that long or short sleep duration increased the risk of sarcopenia and this association was more pronounced in women than men. Among the seven studies examining the relationship between frailty and sleep, four reported that higher Pittsburgh Sleep Quality Index (PSQI) scores were associated with an increased risk of frailty. Practical implications Most previous studies have focused on interventions targeting a single area such as muscle strength or exercise habits, in older adults at risk for frailty. The results suggest that interventions targeting improved sleep may positively impact the maintenance of muscle strength. Originality/value The literature review revealed that too much or too little sleep increases the risk of sarcopenia in older adults. Further, sleep deprivation, greater night-time wakefulness and reduced sleep quality increase the risk of frailty. Interestingly, the risk of mortality is increased in individuals with daytime functional disorders such as excessive drowsiness or napping habits.

scholarly journals Absence of age and gender effects on the pharmacokinetics of a single 500-milligram oral dose of levofloxacin in healthy subjects.

1997 ◽  
Vol 41 (7) ◽  
pp. 1562-1565 ◽  
Author(s):  
S C Chien ◽  
A T Chow ◽  
J Natarajan ◽  
R R Williams ◽  
F A Wong ◽  
...  
Keyword(s):  
Renal Function ◽  
Healthy Subjects ◽  
Age Groups ◽  
The Elderly ◽  
Gender Effects ◽  
Pharmacokinetic Parameters ◽  
Age And Gender ◽  
Male And Female ◽  
Young Males ◽  
And Gender

The influence of age and gender on the pharmacokinetics of levofloxacin in healthy subjects receiving a single oral 500-mg dose of levofloxacin was investigated in this parallel design study. Six young males (aged 18 to 40 years), six elderly males (aged > or = 65 years), six young females (aged 18 to 40 years), and six elderly females (aged > or = 65 years) were enrolled and completed the study. The study reveals that the bioavailability (rate and extent) of levofloxacin was not affected by either age or gender. In both age (young and elderly) and gender (male and female) groups of subjects, peak concentrations in plasma were reached at approximately 1.5 h after dosing; renal clearance of levofloxacin accounted for approximately 77% of total body clearance, and approximately 76% of the administered dose was recovered unchanged in urine over the 36 h of collection. The apparent differences in the calculated pharmacokinetic parameters for levofloxacin between the age groups (young versus elderly) and between the gender groups (males versus females) could be explained by differences in renal function among the subjects. A single dose of 500 mg of levofloxacin administered orally to both young and old, male and female healthy subjects was found to be safe and well tolerated. As the differences in levofloxacin kinetics between the young and the elderly or the males and the females are limited and are mainly related to the renal function of the subjects, dose adjustment based on age or gender alone is not necessary.

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