scholarly journals Detection of IgG and IgM Levels in Patients with COVID-19 in Mosul Province, Iraq

2022 ◽  
Author(s):  
Hasan Faisal Hussein Kahya ◽  
Mohammed Taha Mahmood
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Symptom Onset ◽  
Statistical Difference ◽  
Control Groups ◽  
Serum Samples ◽  
And Control

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) has become the most dangerous viral infection worldwide. Since its identification in late 2019, the number of medical trials to combat the infection has sharply increased. Here, we investigated the profiles of IgG and IgM in 85 patients with confirmed SARS-CoV-2 infection from day 1 after symptom onset until day 35 with 5-day intervals. Serum samples were collected and stored until use. We observed that IgM levels were detectable on day 5 post symptom onset and increased sharply, with the highest rate detected in moderate cases (32.332 ± 4.32, n=10). Subsequently, a significant reduction in IgM was observed until it was undetectable on day 35 after symptom onset. Meanwhile, IgG levels were detected on day 10 post symptom onset, and the highest rate was observed in moderate cases (8.232 ± 2.3, n=10). A significant increase in IgG rate was observed in all patients, with the highest rate in moderate cases (42.432 ± 4.34, n=67) on day 35 post symptom onset. The statistical difference between the case and control groups was significant (p≤0.001). Two out of 85 patients died during the study.

scholarly journals Biomonitoring Data for Assessing Aflatoxins and Ochratoxin A Exposure by Italian Feedstuffs Workers

Toxins ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 351 ◽  
Author(s):  
Barbara De Santis ◽  
Francesca Debegnach ◽  
Elisa Sonego ◽  
Gianmarco Mazzilli ◽  
Francesca Buiarelli ◽  
...  
Keyword(s):  
Ochratoxin A ◽  
Statistical Difference ◽  
High Resolution Mass Spectrometry ◽  
Control Group ◽  
Control Groups ◽  
Serum Samples ◽  
Limit Of Quantification ◽  
Liquid Liquid Extraction ◽  
And Control

Mycotoxins exposure by inhalation and/or dermal contact is possible in different branches of industry especially where heavily dusty settings are present and the handling of dusty commodities is performed. This study aims to explore the validity of the biomonitoring as a tool to investigate the intake of mycotoxins in a population of workers operating in an Italian feed plant. Serum samples were collected for the determination of aflatoxins B1 (AFB1), AFB1-Lysine adduct and ochratoxin A (OTA). A method based on liquid–liquid extraction coupled with high resolution mass spectrometry determination was developed and fully validated. For AFB1, a high number of non-detected samples (90%) was found and no statistical difference was observed comparing workers and control group. None of the analyzed samples showed the presence of AFB1-Lysine adduct. For OTA, the 100% of the analyzed samples was positive with a 33% of the samples showing a concentration higher than the limit of quantification (LOQ), but no statistical difference was highlighted between the average levels of exposed and control groups. In conclusion, the presence of AFB1 and OTA in serum cannot be attributable to occupational exposure.

scholarly journals Postoperative analgesia effects of sulfentanyl plus dexmedetomidine in patients received VATS

Pteridines ◽  
2020 ◽  
Vol 31 (1) ◽  
pp. 55-60
Author(s):  
Haoyu Jiang ◽  
Ying Zheng ◽  
Chang Liu ◽  
Ying Bao
Keyword(s):  
Statistical Difference ◽  
Control Group ◽  
Control Groups ◽  
Significant Statistical Difference ◽  
Post Surgery ◽  
Intravenous Analgesia ◽  
The Mean ◽  
Nsclc Patients ◽  
And Control ◽  
Time Point

AbstractBackground To evaluate sulfentanyl combined with dexmedetomidine hydrochloride on postoperative analgesia in patients who received video-assisted thoracic surgery (VATS) and its effects on serum norepinephrine (NE), dopamine (DA), 5-hydroxytryptamine (5-HT), and prostaglandin (PGE2).Material and Methods Ninety-nine non-small cell lung cancer (NSCLC) patients who received VATS were included in the study. All the patients received intravenous inhalation compound anesthesia. Of the 99 cases, 49 subjects (control group) received sulfentanyl for patient controlled intravenous analgesia (PICA) and other 50 cases (experiment group) received sulfentanyl combined with dexmedetomidine hydrochloride for PICA after operation of VATS. The analgesic effects of the two groups were evaluated according to Visual Analogue Scales (VAS) and the Bruggrmann Comfort Scale (BCS). The serum pain mediator of NE, DA, 5-HT, and PGE2 were examined and compared between the two groups in the first 24 h post-surgery.Results The VAS scores for the experiment group were significant lower than that of control group on the time points of 8, 16, and 24 h post-surgery (pall<0.05), and the BCS scores of the experiment group in the time points of 8, 16, and 24 h were significantly higher than that of controls (p<0.05). However, the VAS and BCS scores were not statistical differently in the time point of 1, 2, and 4 h post-surgery (pall>0.05). The mean sulfentanyl dosage was 63.01 ± 5.14 μg and 67.12 ± 6.91 μg for the experiment and control groups respectively with significant statistical difference (p<0.05). The mean analgesic pump pressing times were 4.30 ± 1.31 and 5.31 ± 1.46 for experiment and control groups respectively with significant statistical difference (p<0.05). The serum NE, DA, 5-HT, and PGE2 levels were significantly lower in the experimental group compared to that of control group in the time point of 12 h post-surgery (pall<0.05). The side effects of nausea, vomiting, delirium, rash, and hypotension atrial fibrillation were not statistically different between the two groups (pall>0.05).Conclusion Patient controlled intravenous analgesia of sulfentanyl combined with dexmedetomidine hydrochloride was effective in reducing the VAS score and serum pain mediators in NSCLC patients who received VAST.

scholarly journals Comparison of Coombs Gel Test with ELISA and Standard Tube Agglutination Tests Used in Serological Diagnosis of Brucellosis

2020 ◽  
Vol 2 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Cigdem Akalan Kuyumcu ◽  
Serpil Erol ◽  
Rıza Adaleti ◽  
Seniha Senbayrak ◽  
Secil Deniz ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Diagnostic Tests ◽  
Serological Test ◽  
High Sensitivity ◽  
Serological Diagnosis ◽  
Control Groups ◽  
Serum Samples ◽  
Serological Tests ◽  
Reliable Test ◽  
And Control

Objective: Serological tests are the most commonly used tests in the diagnosis of brucellosis; however, each serological test has some drawbacks. In this study, we aimed to determine the value of the Brucella Coombs gel test (BCGT) in the serological diagnosis of brucellosis in comparison with Standard tube agglutination (STA) and ELISA tests. Materials and Methods: The study included 42 patients who were considered to have brucellosis as a preliminary diagnosis. BCGT, Brucella-IgM/IgG ELISA, and STA tests were performed from serum samples of the patients. The correlation of the diagnostic tests was analyzed using Cohen’s Kappa Analysis.  Results: Twenty-seven (64.2%) of 42 patients were diagnosed with brucellosis according to their medical history and clinical and serological tests. The sensitivity and specificity of BCGT to diagnose brucellosis was 96.2%, and 100%, respectively. The sensitivity and specificity for the diagnosis of brucellosis 62.9% and 100% for STA, respectively; 33.3% and 66.6% for Brucella-IgM; and 66.6% and 100% for Brucella-IgG. BCGT was significantly correlated with STA (κ= 0.590) and Brucella-IgG (κ=0.539) Conclusion: BCGT can be utilized as a simple and reliable test in the diagnosis of brucellosis with high sensitivity and specificity. Nevertheless, the sensitivity and specificity of BCGT should be demonstrated by comprehensive studies, including culture-confirmed cases and control groups.

scholarly journals Cryotherapy Reduced Postoperative Pain in Gynecologic Surgery: A Randomized Controlled Trial

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Apisada Chumkam ◽  
Densak Pongrojpaw ◽  
Athita Chanthasenanont ◽  
Junya Pattaraarchachai ◽  
Kornkarn Bhamarapravatana ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Statistical Difference ◽  
Controlled Trial ◽  
Exploratory Laparotomy ◽  
Gynecologic Surgery ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
Vas Score ◽  
And Control

Objective. To examine the effectiveness of cryotherapy for reducing postoperative pain in patients who underwent exploratory laparotomy for gynecologic surgery. Materials and Methods. Patients who had indication for an exploratory laparotomy gynecologic procedure were selected by attending physicians to undergo abdominal surgery via low transverse skin incision. The participants were randomized into study and control groups with simple random sampling methods. Cold packs were applied at two hours after operation for 6 hours. The visual analog scale (VAS) score was recorded at two, 6, and 12 hours after operation. Result. One hundred cases were recruited and then divided into study and control groups equally. The mean age of both groups was 43 years. There was no difference in demographics data of both groups. Half of the participants in both groups underwent hysterectomies. At two hours after surgery, both groups had similar VAS scores. The study group had a lower VAS score at 6 and 12 hours after surgery than the control group with statistical difference. Morphine consumption within 24 hours after surgery in both the study and control groups was 2.8±3.4 and 3.0±4.4 mg, respectively, with no statistical difference. However the registration time of the first morphine requirement in the study group was statistically more prolonged than that of the control group. The lengths of hospital stay in both groups were similar. There was no complication reported in this study. Conclusion. Cryotherapy can reduce postoperative pain. In this presented study the patients who underwent gynecologic surgery had improved pain relief and prolonged time for the first dose of the analgesic drug.

Effect of Aspirin Pre- and Postburn on Survival of Experimental Intermediate Burns in Rats

2011 ◽  
Vol 15 (2) ◽  
pp. 111-114
Author(s):  
Eran Hadad ◽  
Melvyn Westreich ◽  
Tal Friedman ◽  
Avshalom Shalom
Keyword(s):  
Health Care ◽  
Cell Death ◽  
Statistical Difference ◽  
Burn Injury ◽  
Control Group ◽  
Control Groups ◽  
Burn Wound ◽  
Major Health ◽  
Flap Survival ◽  
And Control

Background:Burns are a major health care problem. Early treatment increases survival of intermediate burn zones, thus decreasing morbidity, mortality, surgery, and hospitalization. Previously, aspirin was shown to improve burn perfusion and increase failing flap survival.Objective:Owing to similarities between failing flaps and intermediate burn zones, we conducted this study to evaluate the effect of aspirin on intermediate burn zone survival.Methods:An intermediate burn was created in 30 rats randomly divided into three experimental groups: pre- and postburn aspirin groups and a control group. Final burn survival was evaluated on day 7.Results:No statistical difference was observed between the test and control groups. Both aspirin regimens failed to improve intermediate burn survival.Conclusion:Presumably, administration of aspirin could not prevent the noxious tissue events of burn injury that cause cell death. Possibly, different dosages or modes of administering aspirin could have a beneficial effect on burn wound survival.

scholarly journals The Effectiveness of a Training Program Based on Goal Orientations Among Jordanian Students

SAGE Open ◽  
2017 ◽  
Vol 7 (4) ◽  
pp. 215824401773556
Author(s):  
Adnan Yousef Atoum ◽  
Hind Hussain Abu-Hilal
Keyword(s):  
Training Program ◽  
Goal Orientation ◽  
Statistical Difference ◽  
Goal Orientations ◽  
Validity And Reliability ◽  
Control Groups ◽  
Reliability Indicators ◽  
Orientation Scale ◽  
And Control ◽  
Experimental Group

The present study aimed at exploring the effectiveness of a training program based on goal orientations. A sample of 69 female students at Tala’ Al-Ali School in Jordan was chosen and distributed randomly into the experimental and control groups. To achieve the objectives of this study, the researchers had constructed training program to modify students’ types of goal orientation. Also, the researchers developed the goal orientation scale and obtained good validity and reliability indicators. The results showed that there was a significant statistical difference at the level of α ≤ .05 in the postscores of the goal orientation domains in favor of the experimental group. In addition, there was no statistical difference at the level of α ≤ .05 between the posttest and delayed scores in the experimental group indicating the continuity of the effect of the training program on the experimental group.

scholarly journals High prevalence of intrathecal IgA synthesis in multiple sclerosis patients

2021 ◽  
Author(s):  
Ursula Muñoz ◽  
Cristina Sebal ◽  
Esther Escudero ◽  
Maria Isabel García Sánchez ◽  
Elena Urcelay ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Neurological Diseases ◽  
Control Group ◽  
Control Groups ◽  
Serum Samples ◽  
Highly Sensitive ◽  
High Prevalence ◽  
Ultrasensitive Assay ◽  
Multiple Sclerosis Patients ◽  
And Control

Abstract Introduction: The detection of intrathecal IgA synthesis (IAS) in multiple sclerosis (MS) is cumbersome, for this reason, we developed a highly sensitive assay to assess it in MS. Methods: 151 MS patients and 22 controls with different neurological diseases were recruited. IgA concentration was analyzed by ELISA. Oligoclonal IgA bands to detect IAS were determined by a new ultrasensitive assay based on isoelectrofocusing (IEF). Results: Most individuals showed an IgA concentration within normal range in serum samples (95.95%) but 38.41% of individuals had a low IgA concentration in the cerebrospinal fluid (CSF), with no significant differences observed between MS and control groups, neither in CSF nor in serum. The new IEF was more sensitive than those previously described (0.01 mg/dl of IgA), and clearly identified patients with and without IAS, that was not related with IgA concentration. MS patients showed higher percentage of IAS (43.00%) than the control group (18.20) (p = 0.035), because the incidence was especially higher in MS patients with clinically isolated syndrome (CIS, 66.00%). Conclusions: Intrathecal IgA synthesis is observed more frequently in MS patients than in other neurological diseases, and with higher incidence than assumed in the past.

scholarly journals Analysis of isokinetic knee strength in soccer players in terms of selected parameters

2018 ◽  
Vol 23 (4) ◽  
pp. 209-216 ◽  
Author(s):  
A.K. Yılmaz ◽  
M. Kabadayı ◽  
Ö. Bostancı ◽  
M. Özdal ◽  
M.H. Mayda
Keyword(s):  
Body Composition ◽  
Statistical Difference ◽  
Soccer Player ◽  
Personal Information ◽  
Knee Extension ◽  
Soccer Players ◽  
Control Groups ◽  
Knee Strength ◽  
Body Mass Indexes ◽  
And Control

Purpose: The aim of study is to analyse isokinetic knee strength in soccer players in terms of selected parameters. Methods: A total of 30 subjects, 15 soccer players and 15 controls, were included in the study. Isokinetic knee strength measurements at angular speeds of 60°sec-1, 180°sec-1 and 240°sec-1 and pro-agility tests were conducted on the subjects. A body analyser was used for height, weight and body mass indexes (BMI) values. The training ages of the subjects and the positions of the soccer player group were recorded on personal information forms. Results: When the agility parameters were compared between football and control groups, a statistical difference was found in favour of the soccer player group (p < 0.05). When the effects of body composition and isokinetic knee strength on agility were analysed, negative significant correlation was found between weight and agility, BMI and agility and 240° right knee extension strength and agility (p < 0.05). When the positions of soccer players and isokinetic knee strengths were compared, significance was found between 60° right extension strength of defenders and midfielders and 60° left extension-flexion strengths of defenders and midfielders and forwards in favour of defenders (p > 0.05). Conclusions: In conclusion, it was found that isokinetic knee strength did not have an influence on agility in low angular speeds, except for 240°sec-1 right extension. According to positions, as the isokinetic knee strength of defenders decreased, they showed higher results when compared with other positions.

ANALYSIS OF THE LONG-TERM SICKNESS RATE AMONG AIRLINE PILOTS

2021 ◽  
Vol 55 (4) ◽  
pp. 51-59
Author(s):  
I.V. Bukhtiyarov ◽  
◽  
E.V. Zibarev ◽  
М.Е. Fomina ◽  
V.S. Mikueva ◽  
...  
Keyword(s):  
Statistical Difference ◽  
Flight Mechanics ◽  
Work Intensity ◽  
Control Groups ◽  
Prostate Hyperplasia ◽  
Acoustic Environment ◽  
Airline Pilots ◽  
Acoustic Environments ◽  
Intensive Work ◽  
And Control

Retrospective health analysis was performed having the data from 211 airline pilots and 168 flight mechanics with symptoms of chronic neurosensorybradyacusia gathered in the period from 2015 to 2020. There were 2 control groups. One group consisted of bus drivers comparable to pilots in terms of acoustic environment and work intensity. The other group included power station operators working in standard acoustic environments and doing intensive work. The investigation revealed a statistical difference between the pilots and control groups in the rates of cardiovascular diseases (22.45 vs. 7.08 and 71.19 in the control groups), respiratory diseases (0.18 vs. 0.07 and 0.44), digestive diseases (17.13 vs. 1.90 and 154.21), musculoskeletal (15.44 vs. 15.44 and 254.97), neural, urogenital diseases (11.49 vs. 0.79 and 167.61). In comparison with the control groups, pilots were at a higher risk of cerebral atherosclerosis (13.79 vs. 2.81 and 67.58), essential hypertension (14.25 vs. 1.01 and 200.78), spinal osteochondrosis (3.00 vs. 0.39 and 22.95), prostate hyperplasia (2.29 vs. 0.11 and 48.82) and chronic prostatitis (3.43 vs. 0.20 and 57.65). Also stated was a statistical difference in the medium of chronic diseases at the retirement age in pilots and flight mechanics in comparison with the control members: (6 (4–8) pilots, 6 (4.5–8.0) flight mechanics, 3 (1–5) drivers, 2 (1–3) operators; р< 0.05).

scholarly journals Serum Metabolomics Profiling to Identify Biomarkers for Unstable Angina

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Wei Yao ◽  
Yuxia Gao ◽  
Zheng Wan
Keyword(s):  
Angina Pectoris ◽  
Unstable Angina ◽  
Unstable Angina Pectoris ◽  
Control Groups ◽  
Serum Samples ◽  
Mortality And Morbidity ◽  
H Nmr ◽  
And Control ◽  
Insight Into ◽  
Serum Metabolomics

Although statistical evidence is clear regarding the dangerousness of unstable angina (UA), a form of coronary heart disease (CHD) characterised by high mortality and morbidity globally, it is important to recognise that diagnostic precision for the condition is unfavourable. In the present research, to gain insight into candidate biomarkers, the author draws on1H NMR-based serum metabolic profiling to analyze the unstable angina pectoris (UAP) metabolic signatures; this constitutes an effective way to produce medical diagnosis. 101 unstable angina pectoris patients and 132 healthy controls were enrolled and 22 serum samples from each group were analyzed. Effective separation was noted regarding the UAP and control groups, and, for the former group considered in relation to their counterpart, the serum concentrations of Lac, m-I, lipid, VLDL, 3-HB, and LDL were higher whereas the concentrations of Thr, Cr, Cho, PC/GPC, Glu, Gln, Lys, HDL, Ile, Leu, and Val were lower. The conclusion drawn in view of the results is that the plasma metabolomics examined by1H NMR displayed promise for biomarker identification for UA. In addition to this, the analysis illuminated the metabolic processes of UA.

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