Enhancement Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression of Macrobrachium rosenbergii Fed With Aqueous Morinda citrifolia Leaves Extract-Supplemented Diet

Morinda citrifolia, known commercially as noni is often used for enhance immunity, these plant rich of phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed with diets containing of aqueous M. citrifolia leaves extract (AMLE) at 0.6, 4 and 6 g kg-1. Glutathione peroxidase (GPx) activity was conducted to measure immune parameter, these parameter was evaluated before and after 7, 21, 35, 49 and 63 days of feeding trial. Immune gene expression of α2-macroglubulin (α2-M) was evaluated in this study. The results showed that after 63 days of feeding treatment, significantly increased in GPx activity. Gene expressions of α2-macroglubulin was significantly upregulated. These results recommend that administration of AMLE can be used as an immunostimulant and regulated immune response and immune gene expression in M. rosenbergii. Keyword: Morinda citrifolia, Macrobrachium rosenbergii, GPx, α2-M

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Aqueous Morinda citrifolia Leaves Extract Enhancing Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression on Macrobrachium rosenbergii

Research Journal of Life Science ◽

10.21776/ub.rjls.2017.004.01.4 ◽

2017 ◽

Vol 4 (1) ◽

pp. 25-33 ◽

Cited By ~ 1

Author(s):

Atika Marisa Halim

Keyword(s):

Gene Expression ◽

Glutathione Peroxidase ◽

Peroxidase Activity ◽

Macrobrachium Rosenbergii ◽

Morinda Citrifolia ◽

Glutathione Peroxidase Activity ◽

Α2 Macroglobulin

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Effects of Moringa oleifera leaf extract on growth performance, physiological and immune response, and related immune gene expression of Macrobrachium rosenbergii with Vibrio anguillarum and ammonia stress

Fish & Shellfish Immunology ◽

10.1016/j.fsi.2019.03.039 ◽

2019 ◽

Vol 89 ◽

pp. 603-613 ◽

Cited By ~ 8

Author(s):

Ivan Venkonwine Kaleo ◽

Qiang Gao ◽

Bo Liu ◽

Cunxin Sun ◽

Qunlan Zhou ◽

...

Keyword(s):

Gene Expression ◽

Immune Response ◽

Growth Performance ◽

Leaf Extract ◽

Moringa Oleifera ◽

Vibrio Anguillarum ◽

Macrobrachium Rosenbergii ◽

Immune Gene ◽

Immune Gene Expression ◽

Ammonia Stress

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Faculty Opinions recommendation of Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732026813.793548288 ◽

2018 ◽

Author(s):

Ashish Kamat

Keyword(s):

Gene Expression ◽

Bladder Cancer ◽

Expression Patterns ◽

Transcriptomic Analysis ◽

Gene Expression Patterns ◽

Immune Gene ◽

Immune Gene Expression ◽

Prognostic Relevance

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Author Contributions:Anne Bakke: Conceptualization, Methodology, Writing – original draft preparation, Writing – review & editing; Alexander Rebl: Conceptualization, Methodology; Petter Frost: Writing – review & editing; Sergey Afanasyev: Software and Data curation; Kristoffer Alnes Røyset: Methodology, Writing – review & editing; Tina Søfteland: Writing – review & editing; Hege Lund: Conceptualization, Writing – review & editing, Supervision; Preben Boysen: Conceptualization, Writing – review & editing, Supervision, Project administration and Funding acquisition; Aleksei Krasnov: Conceptualization, Methodology, Writing – original draft preparation, Writing – review & editing, Project administration and Funding acquisition, All authors have read and agreed to the published version of the manuscript.Effect of two constant light regimens on antibody profiles and immune gene expression in atlantic salmon following vaccination and experimental challenge with salmonid alphavirus

Fish & Shellfish Immunology ◽

10.1016/j.fsi.2021.07.002 ◽

2021 ◽

Author(s):

Anne Bakke ◽

Alexander Rebl ◽

Petter Frost ◽

Sergey Afanasyev ◽

Kristoffer Alnes Røyset ◽

...

Keyword(s):

Gene Expression ◽

Atlantic Salmon ◽

Data Curation ◽

Constant Light ◽

Immune Gene ◽

Immune Gene Expression ◽

Experimental Challenge

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Impacts of pineapple peel powder on growth performance, innate immunity, disease resistance, and relative immune gene expression of Nile tilapia, Oreochromis niloticus

Fish & Shellfish Immunology ◽

10.1016/j.fsi.2021.04.002 ◽

2021 ◽

Author(s):

Hien Van Doan ◽

Seyed Hossein Hoseinifar ◽

Ramasamy Harikrishnan ◽

Trisadee Khamlor ◽

Montri Punyatong ◽

...

Keyword(s):

Gene Expression ◽

Innate Immunity ◽

Disease Resistance ◽

Growth Performance ◽

Oreochromis Niloticus ◽

Nile Tilapia ◽

Immune Gene ◽

Immune Gene Expression ◽

Nile Tilapia Oreochromis Niloticus ◽

Pineapple Peel

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Immune gene expression in cyprinid herpesvirus-2 (CyHV-2)–sensitized peripheral blood leukocytes (PBLs) co-cultured with CyHV-2-infected goldfish fin cell line

Aquaculture International ◽

10.1007/s10499-021-00721-6 ◽

2021 ◽

Author(s):

Sweta Das ◽

Arathi Dharmaratnam ◽

Charan Ravi ◽

Raj Kumar ◽

Thangaraj Raja Swaminathan

Keyword(s):

Gene Expression ◽

Cell Line ◽

Peripheral Blood ◽

Immune Gene ◽

Peripheral Blood Leukocytes ◽

Blood Leukocytes ◽

Immune Gene Expression

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Larvae and adults exhibit contrasting patterns of immune gene expression and infection resistance in wild flour beetle populations

Ecological Entomology ◽

10.1111/een.13066 ◽

2021 ◽

Author(s):

Ann T. Tate ◽

Abby Perry ◽

Derrick Jent

Keyword(s):

Gene Expression ◽

Immune Gene ◽

Flour Beetle ◽

Immune Gene Expression ◽

Infection Resistance

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Impact of cinnamaldehyde on innate immunity and immune gene expression in Channa striatus against Aphanomyces invadans

Fish & Shellfish Immunology ◽

10.1016/j.fsi.2021.07.009 ◽

2021 ◽

Author(s):

Ramasamy Harikrishnan ◽

Gunapathy Devi ◽

Chellam Balasundaram ◽

Hien Van Doan ◽

Sanchai Jaturasitha ◽

...

Keyword(s):

Gene Expression ◽

Innate Immunity ◽

Immune Gene ◽

Channa Striatus ◽

Immune Gene Expression

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Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer

Communications Biology ◽

10.1038/s42003-021-01842-7 ◽

2021 ◽

Vol 4 (1) ◽

Author(s):

Ling Cai ◽

Hongyu Liu ◽

Fang Huang ◽

Junya Fujimoto ◽

Luc Girard ◽

...

Keyword(s):

Gene Expression ◽

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Neuroendocrine Cells ◽

Immune Gene ◽

Small Cell Lung ◽

Immune Gene Expression ◽

Pulmonary Neuroendocrine Cells

AbstractSmall cell lung cancer (SCLC) is classified as a high-grade neuroendocrine (NE) tumor, but a subset of SCLC has been termed “variant” due to the loss of NE characteristics. In this study, we computed NE scores for patient-derived SCLC cell lines and xenografts, as well as human tumors. We aligned NE properties with transcription factor-defined molecular subtypes. Then we investigated the different immune phenotypes associated with high and low NE scores. We found repression of immune response genes as a shared feature between classic SCLC and pulmonary neuroendocrine cells of the healthy lung. With loss of NE fate, variant SCLC tumors regain cell-autonomous immune gene expression and exhibit higher tumor-immune interactions. Pan-cancer analysis revealed this NE lineage-specific immune phenotype in other cancers. Additionally, we observed MHC I re-expression in SCLC upon development of chemoresistance. These findings may help guide the design of treatment regimens in SCLC.

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