scholarly journals A study on serum ferritin and its correlation with metabolic syndrome

2022 ◽  
Vol 4 (1) ◽  
pp. 05-07
Author(s):  
Dr. N Ravikanth ◽  
Dr. Saritha K Narayanan ◽  
Dr. M Ramakrishna Rao
Keyword(s):  
Metabolic Syndrome ◽  
Serum Ferritin

scholarly journals Total and Nonheme Dietary Iron Intake Is Associated with Metabolic Syndrome and Its Components in Chinese Men and Women

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1663 ◽  
Author(s):  
Zhenni Zhu ◽  
Fan Wu ◽  
Ye Lu ◽  
Chunfeng Wu ◽  
Zhengyuan Wang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Serum Ferritin ◽  
Smoking Status ◽  
Heme Iron ◽  
Nonheme Iron ◽  
Total Iron ◽  
Positive Trend ◽  
Dietary Iron ◽  
Iron Intake ◽  
Men And Women

The causal relationship between serum ferritin and metabolic syndrome (MetS) remains inconclusive. Dietary iron intake increases serum ferritin. The objective of this study was to evaluate associations of total, heme, and nonheme dietary iron intake with MetS and its components in men and women in metropolitan China. Data from 3099 participants in the Shanghai Diet and Health Survey (SDHS) obtained during 2012–2013 were included in this analysis. Dietary intake was assessed by 24-h diet records from 3 consecutive days. Multivariate generalized linear mixed models were used to evaluate the associations of dietary iron intake with MetS and its components. After adjustment for potential confounders as age, sex, income, physical exercise, smoking status, alcohol use, and energy intake, a positive trend was observed across quartiles of total iron intake and risk of MetS (p for trend = 0.022). Compared with the lowest quartile of total iron intake (<12.72 mg/day), the highest quartile (≥21.88 mg/day) had an odds ratio (95% confidence interval), OR (95% CI), of 1.59 (1.15,2.20). In addition, the highest quartile of nonheme iron intake (≥20.10 mg/day) had a 1.44-fold higher risk of MetS compared with the lowest quartile (<11.62 mg/day), and higher risks of MetS components were associated with the third quartiles of total and nonheme iron intake. There was no association between heme iron intake and risk of MetS (p for trend = 0.895). Associations for total and nonheme iron intake with MetS risk were found in men but not in women. Total and nonheme dietary iron intake was found to be positively associated with MetS and its components in the adult population in metropolitan China. This research also revealed a gender difference in the association between dietary iron intake and MetS.

scholarly journals Serum Ferritin Is Associated with Metabolic Syndrome and Red Meat Consumption

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Avila Felipe ◽  
Echeverría Guadalupe ◽  
Pérez Druso ◽  
Martinez Carlos ◽  
Strobel Pablo ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Serum Ferritin ◽  
Wide Spectrum ◽  
Hdl Cholesterol ◽  
Meat Consumption ◽  
Mean Value ◽  
Red Meat ◽  
Ferritin Concentration ◽  
Stress Markers ◽  
Serum Ferritin Concentration

Background and Aims. Hyperferritinemia has been related with a wide spectrum of pathologies, including diabetes, cardiovascular disease, neurodegenerative disorders, and metabolic syndrome. The aim of this study was to investigate the association between hyperferritinemia and iron consumption.Methods and Results. Serum ferritin concentration was evaluated in 66 presumed healthy men, along with other clinical and biochemical markers of chronic diseases. A three-day food questionnaire was applied for nutrition information. Hyperferritinemia was a condition found in 13.4% of the volunteers analyzed. Significant correlations were found between serum ferritin concentration and metabolic syndrome parameters (HDL cholesterol, triglycerides, and fasting glucose) as well as an increase of the serum ferritin mean value with the number of risk factors of metabolic syndrome. Also, oxidative stress markers (carbonyl groups, AOPP, and glycated hemoglobin), hepatic damage markers (GGT, SGOT), and parameters related to insulin resistance (HOMA, blood insulin, and blood glucose) correlate significantly with serum ferritin. Volunteers had an excessive iron intake, principally by bread consumption. Analyses of food intake showed that red meat consumption correlates significantly with serum ferritin.Conclusion. Red meat consumption, metabolic syndrome, and chronic disease markers are associated with hyperferritinemia in a population of Chilean men.

scholarly journals Serum ferritin contributes to racial or geographic disparities in metabolic syndrome in Taiwan

2013 ◽  
Vol 17 (7) ◽  
pp. 1498-1506 ◽  
Author(s):  
Jung-Su Chang ◽  
Shiue-Ming Lin ◽  
Jane C-J Chao ◽  
Yi-Chun Chen ◽  
Chi-Mei Wang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Indigenous People ◽  
Racial Differences ◽  
Serum Ferritin ◽  
Hdl Cholesterol ◽  
Han Chinese ◽  
The Body ◽  
Cross Sectional ◽  
Geographic Disparities ◽  
Increased Risk

AbstractObjectivesAsians and Pacific Islanders have higher circulating serum ferritin (SF) compared with Caucasians but the clinical significance of this is unclear. There is a higher prevalence of metabolic syndrome (MetS) in Taiwanese Indigenous than Han Chinese. Genetically, Indigenous are related to Austronesians and account for 2 % of Taiwan's population. We tested the hypothesis that accumulation of Fe in the body contributes to the ethnic/racial disparities in MetS in Taiwan.DesignA population-based, cross-sectional study.SettingNational Nutrition and Health Survey in Taiwan and Penghu Island.SubjectsA total of 2638 healthy adults aged ≥19 years. Three ethnic groups were included.ResultsHan Chinese and Indigenous people had comparable levels of SF. Austronesia origin was independently associated with MetS (OR = 2·61, 95 % CI 2·02, 3·36). After multiple adjustments, the odds for MetS (OR = 2·49, 95 % CI 1·15, 5·28) was significantly higher among Indigenous people in the highest SF tertile compared with those in the lowest tertile. Hakka and Penghu Islanders yielded the lowest risks (OR = 1·08, 95 % CI 0·44, 2·65 and OR = 1·21, 95 % CI 0·52, 2·78, respectively). Indigenous people in the highest SF tertile had increased risk for abnormal levels of fasting glucose (OR = 2·34, 95 % CI 1·27, 4·29), TAG (OR = 1·94, 95 % CI 1·11, 3·39) and HDL-cholesterol (OR = 2·10, 95 % CI 1·18, 3·73) than those in the lowest SF tertile.ConclusionsOur results raise the possibility that ethnic/racial differences in body Fe store susceptibility may contribute to racial and geographic disparities in MetS.

The relationship between serum ferritin and metabolic syndrome in healthy Korean men

2011 ◽  
Vol 27 (6) ◽  
pp. 597-603 ◽  
Author(s):  
Jae-Hong Ryoo ◽  
Min-Gi Kim ◽  
Da-Woon Lee ◽  
Ju-Young Shin
Keyword(s):  
Metabolic Syndrome ◽  
Serum Ferritin ◽  
The Relationship

scholarly journals Iron Homeostasis in Patients with Nonalcoholic Fatty Liver Disease

2021 ◽  
Vol 08 (02) ◽  
pp. 6-10
Author(s):  
Kuldeep Kumar ◽  
Keyword(s):  
Metabolic Syndrome ◽  
Liver Disease ◽  
Fatty Liver ◽  
Serum Ferritin ◽  
Fatty Liver Disease ◽  
Iron Status ◽  
Positive Association ◽  
Control Group ◽  
Significant Positive Association ◽  
Serum Hepcidin

Introduction: Serum ferritin correlates with hepatic iron deposition in patients with Non Alcoholic Fatty Liver Disease (NAFLD). Iron removal improves insulin sensitivity thereby delaying the onset of type 2 diabetes mellitus, improves liver function and NAFLD histology. Objectives: This study was done to assess the iron status in NAFLD patients and its association with fibrosis and metabolic syndrome in NAFLD. Material and Method: The study was conducted in the Department of Medicine, GTB Hospital, Delhi from November 2017 - October 2019. It was an Analytical, comparative study. Forty patients with NAFLD were selected in the study group and forty healthy subjects with no evidence of fatty liver on ultrasound were selected in the control group. The level of iron parameters recorded in NAFLD patients and the control group were compared using independent t test and p value of <0.05 was considered statistically significant. Assessment of association of various parameters of iron status with the presence of Metabolic Syndrome and fibrosis in NAFLD patients was done using the Chi-Square test. Result: The parameters of iron status namely serum iron, serum ferritin, transferrin saturation and serum hepcidin were found to be higher in NAFLD patients when compared to controls. This study also observed that there was a statistically significant positive association of serum ferritin with the presence of MetS in NAFLD patients. The study also found that serum hepcidin and serum ferritin have a significant positive association with fibrosis in NAFLD. Discussion: Assessment of iron status in NAFLD may help in early identification of individuals at high risk of fibrosis and other complications like Mets. Application of iron removal strategies like phlebotomy in such patients might improve IR and NAFLD.

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