PARALISIA BULBAR PROGRESSIVA (PBP): relato de caso

2020 ◽  
Vol 6 (2) ◽  
pp. 480-487
Author(s):  
Heuler dos Reis Rodrigues ◽  
Mariane Fernandes Ribeiro ◽  
Carla Cristina Ferreira de Andrade

Motor neuron disease is a term used in several clinical syndromes, among them Progressive Bulbar Paralysis, a rare degenerative and progressive disease of rapid evolution and loss of early respiratory muscle strength. The characteristics are dysphonia, dysphagia, dysarthria, inability in bronchial hygiene, wheezing breaths and atrophy of the tongue musculature, affecting chewing, the grinding of food is increasingly difficult, affecting chewing, causing a potentially disabling and debilitating disease. This study aimed to describe a clinical case of an individual with a clinical diagnosis of Progressive Bulbar Paralysis in Propaedeutics at the Clinical School of the Faculty of the Alto Paranaíba-MG region. The object of study was a 57-year-old male, who underwent an initial physical therapy evaluation and was collected with maximum physiological pressure: maximum inspiratory pressure, maximum expiratory pressure, Borg CR-10 scale, heart rate (HR), respiratory pressure (RF), systolic blood pressure (SBP), diastolic blood pressure (DBP), peripheral oxygen saturation (SPO2). Then, follow a course of action in accordance with the provisions of the literature on the performance of the disease. The results found in this study are satisfactory, for all eight variables analyzed, with the possibility of highlighting the variable Borg CR-10 as the most satisfactory variable compared.

2019 ◽  
Vol 201 ◽  
pp. 06003
Author(s):  
Łukasz Stala ◽  
Krzysztof Tomczuk

The paper presents two methods of determining calibration curve of a new device for blood pressure measurement. The device was developed at Wrocław University of Science and Technology. First method is based on parallel measurement of systolic and diastolic pressure measurement with use of reference device such as sphygmomanometer and researched new device with pneumatic sensor equipped with voltage type output. Obtained data (systolic ps and diastolic pd pressure, maximum us and minimum ud voltage) was then used to determine individual pressure-voltage characteristic of the device, which can be represented as a linear equation. Second method is based on substitution of experimentally proved coefficient b with its analytical equivalent extracted from mathematical model of described pneumatic sensor. Described methods were verified experimentally and compared. Metrological parameters of the device were designated.


2019 ◽  
Vol 90 (e7) ◽  
pp. A33.1-A33
Author(s):  
Chris Blair ◽  
Kartik Bhatia ◽  
David Brunacci ◽  
John Worthington ◽  
Rebekah Ahmed

IntroductionWith approximately 200 procedures performed in the last year at our centre, worthwhile clinical lessons continue to emerge in the practice of endovascular clot retrieval (ECR) for acute stroke. This case demonstrates the value of considered clinical appraisal in a dynamic, information-rich setting. A 68 year-old man with established vertebrobasilar atherosclerotic disease developed capricious, blood pressure-sensitive neurological deficits after successful ECR for a basilar artery stroke, inviting the possibility of further intervention in the form of intracranial stenting. We avoided pursuing this course of action in favour of a more measured approach, entailing the provision of vasopressor support over the following week.MethodFollowing ECR, our patient was admitted to the intensive care unit for continuous blood pressure monitoring and close observation of his neurological deficits with serial NIHSS (National Institutes of Health Stroke Scale) scoring. Systolic blood pressures were maintained between 140–160 mmHg using vasopressor support, with the aim of allowing time for recovery of vascular autoregulation and collateralization.ResultsOver six days, the patient developed moderate left upper and lower limb weakness. An MRI performed on Day 5 revealed limited interval infarction of the right hemipons and cerebellum, with complete re-occlusion of the mid-basilar arterial segment. He left the ICU with a NIHSS score of 7, and was living independently at 90-day follow-up (Modified Rankin Score 1).ConclusionThe ultimately favourable net outcome for our patient clearly illustrates the imperative to remain within the boundaries of evidence-based practice in this bold and rapidly evolving discipline.


1964 ◽  
Vol 110 (467) ◽  
pp. 594-598 ◽  
Author(s):  
Brian Davies ◽  
George Palmai

Many attempts have been made to measure some of the changes in various bodily functions that occur during the course of a depressive illness. These changes (and their responses to drugs) have been used in investigations that try to correlate such changes with the clinical syndromes of “endogenous” and “reactive” depressions (10). No reliable and valid correlations have, however, yet been found (4, 5).


Author(s):  
Sang Hyuk Lee ◽  
Nahmkeon Hur ◽  
Seongwon Kang

Recently, the rapid evolution of numerical methodologies for CFD and structural analyses has made it possible to predict the arterial hemodynamics closely related to vascular disease. In the present study, a framework for fluid-structure interaction (FSI) analysis was developed to accurately predict the arterial hemodynamics. The numerical results from the FSI analysis of the hemodynamics inside aneurysms of various shapes were compared to the results without FSI analysis. The results showed that FSI analysis needs to be performed in order to accurately predict the blood flow affected by the wall motion of compliant arteries. FSI analysis is essential to predict the hemodynamics in a saccular aneurysm because the arterial wall’s movement, which is a result of the variation of blood pressure in the aneurysmal sac, mainly produces the blood flow to a saccular aneurysm.


2021 ◽  
Vol 8 ◽  
Author(s):  
Yun Li ◽  
Lu Wang ◽  
Yuyan Liu ◽  
Yan Zhao ◽  
Yong Fan ◽  
...  

Objective: Most trauma scoring systems with high accuracy are difficult to use quickly in field triage, especially in the case of mass casualty events. We aimed to develop a machine learning model for trauma mortality prediction using variables easy to obtain in the prehospital setting.Methods: This was a retrospective prognostic study using the National Trauma Data Bank (NTDB). Data from 2013 to 2016 were used for model training and internal testing, and data from 2017 were used for validation. A neural network model (NN-CAPSO) was developed using the ability to follow commands (whether GCS-motor was <6), age, pulse rate, systolic blood pressure (SBP) and peripheral oxygen saturation, and a new score (the CAPSO score) was developed based on logistic regression. To achieve further simplification, a neural network model with the SBP variable removed (NN-CAPO) was also developed. The discrimination ability of different models and scores was compared based on the area under the receiver operating characteristic curve (AUROC). Furthermore, a reclassification table with three defined risk groups was used to compare NN-CAPSO and other models or scores.Results: The NN-CAPSO had an AUROC of 0.911(95% confidence interval 0.909 to 0.913) in the validation set, which was higher than the other trauma scores available for prehospital settings (all p < 0.001). The NN-CAPO and CAPSO score both reached the AUROC of 0.904 (95% confidence interval 0.902 to 0.906), and were no worse than other prehospital trauma scores. Compared with the NN-CAPO, CAPSO score, and the other trauma scores in reclassification tables, NN-CAPSO was found to more accurately classify patients to the right risk groups.Conclusions: The newly developed CAPSO system simplifies the method of consciousness assessment and has the potential to accurately predict trauma patient mortality in the prehospital setting.


2021 ◽  
pp. 1357633X2110118
Author(s):  
Nobuyuki Kagiyama ◽  
Makoto Hiki ◽  
Yuya Matsue ◽  
Tomotaka Dohi ◽  
Wataru Matsuzawa ◽  
...  

Introduction In the ongoing COVID-19 pandemic, the development of a system that would prevent the infection of healthcare providers is in urgent demand. We sought to investigate the feasibility and validity of a telemedicine-based system in which healthcare providers remotely check the vital signs measured by patients with COVID-19. Methods Patients hospitalized with confirmed or suspected COVID-19 measured and uploaded their vital signs to secure cloud storage. Additionally, the respiratory rates were monitored using a mat-type sensor placed under the bed. We assessed the time until the values became available on the Cloud and the agreements between the patient-measured vital signs and simultaneous healthcare provider measurements. Results Between 26 May–23 September 2020, 3835 vital signs were measured and uploaded to the cloud storage by the patients ( n=16, median 72 years old, 31% women). All patients successfully learned how to use these devices with a 10-minute lecture. The median time until the measurements were available on the cloud system was only 0.35 min, and 95.2% of the vital signs were available within 5 min of the measurement. The agreement between the patients’ and healthcare providers’ measurements was excellent for all parameters. Interclass coefficient correlations were as follows: systolic (0.92, p<0.001), diastolic blood pressure (0.86, p<0.001), heart rate (0.89, p<0.001), peripheral oxygen saturation (0.92, p<0.001), body temperature (0.83, p<0.001), and respiratory rates (0.90, p<0.001). Conclusions Telemedicine-based self-assessment of vital signs in patients with COVID-19 was feasible and reliable. The system will be a useful alternative to traditional vital sign measurements by healthcare providers during the COVID-19 pandemic.


Author(s):  
Guilherme Rosa ◽  
Tais Paes Guedes ◽  
Thiago de Andrade Silva ◽  
Fábio Dutra Pereira

Introdução: O método de suprimento de ventilação não invasivo (VNI) durante a realização de exercícios físicos tem sido utilizado como uma ferramenta auxiliar no tratamento de pacientes com doenças pulmonares. A literatura mostra que ainda há escassez de dados acerca dos efeitos da utilização da VNI durante a realização do exercício físico sobre os parâmetros cardiorrespiratórios.Objetivo: Avaliar o efeito do exercício físico associado a VNI sobre parâmetros cardiovasculares e respiratórios.Métodos: Participou deste estudo de caso um indivíduo do sexo masculino, saudável, com 27 anos de idade. Foram mensurados: frequência cardíaca (FC), variabilidade cardíaca (VFC), saturação periférica de oxigênio (SPO2), pressão arterial sistólica (PAS) e diastólica (PAD) e duplo produto (DP). Foram realizados dois treinos cardiorrespiratórios em esteira ergométrica, um sem VNI e o outro com VNI. As sessões de treinamento contemplaram duração de 40 min divididos em 5 min de aquecimento com intensidade entre 50% e 55% da FC reserva, 30 min de fase específica com intensidade entre 60% e 85% da FC reserva, e 5 min de desaquecimento com intensidade de 50% a 55% da FC reserva. Para avaliar as alterações das variáveis desfecho, foi estimada a variação percentual pelo coeficiente de variação.Resultados: A realização do exercício com VNI provocou alterações nos parâmetros cardiovasculares e respiratórios analisados, com destaque para redução da VFC (Δ%= -64,14) e PAD (Δ%= -45,82) em comparação à realização sem VNI.Conclusão:  Os resultados do presente estudo sugerem que a realização do exercício físico com VNI pode beneficiar as respostas dos parâmetros cardiovasculares e respiratórios. Os resultados foram discutidos.Acute Effect of Non-Invasive Ventilation Associated with Physical Exercise on Cardiovascular and Respiratory Parameters: a Case StudyIntroduction: The noninvasive ventilation (NIV) method during physical exercise has been used as an auxiliary tool in the treatment of patients with pulmonary diseases. However, there is a lacune on the knowledge about cardiorespiratory parameters effects of NIV during physical exercise.Objective: To evaluate the effect of physical exercise associated with NIV on cardiovascular and respiratory parameters.Methods: A healthy, 27-year-old male was enrolled in this case study. Heart rate (HR), cardiac variability (HRV), peripheral oxygen saturation (SPO2), systolic blood pressure (SBP) and diastolic blood pressure (DBP) and double product (SD) were measured. Two cardiorespiratory treadmills were performed on treadmill, one without NIV and the other with NIV. The training sessions included 40 min duration divided in 5 min of heating with intensity between 50% and 55% of reserve HR, 30 min of specific phase with intensity between 60% and 85% of reserve HR, and 5 min of cooling with intensity of 50% to 55% of reserve FC. To express the changes of the variables, the percentage change was estimated by the coefficient of variation.Results: The exercise with NIV caused changes in cardiovascular and respiratory parameters, with a reduction in HRV (Δ% = -64.14) and DBP (Δ% = -45.82) in comparison with non-NIV.Conclusion: Our findings suggested that physical exercise with NIV use may benefit in association with exercise in relation to cardiovascular and respiratory parameters. The results were discussed.


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