scholarly journals Methods for Mesh Implantation Efficacy Assessment in Rectocele

2021 ◽  
Vol 31 (3) ◽  
pp. 17-25
Author(s):  
A. S. Lukianov ◽  
A. Yu. Titov ◽  
O. M. Biryukov ◽  
A. A. Mudrov ◽  
I. V. Kostarev
Keyword(s):  
Surgical Intervention ◽  
Symptom Assessment ◽  
Research Centre ◽  
Mesh Implantation ◽  
Descending Perineum ◽  
National Medical ◽  
Intervention Efficacy ◽  
Assessment Techniques ◽  
Efficacy Assessment ◽  
Evacuation Disorder

Aim. A methodological review on mesh implantation efficacy assessment in surgery for rectocele.Key points. Specialised quiz surveys are among the most appropriate methods to assess surgical intervention efficacy. The questionnaires that enable pre- and postsurgery rectocele grading include PFDI-20 (Pelvic Floor Distress Inventory), the colonic evacuation disorder scale and Cleveland Constipation Scoring System. These surveys determine the surgical intervention efficacy dynamically in conjunction with instrumental surgery assessment techniques.Conclusion. Clinical practice at the Ryzhikh National Medical Research Centre for Coloproctology combines the originally developed colonic evacuation disorder scale (2003) and PFDI-20. The combined scales allow for a comprehensive symptom assessment in patients with rectocele and other descending perineum syndrome manifestations prior to surgery, as well as symptom dynamics evaluation postoperatively, which, in link with defecography, enables a complete appraisal of the surgical effect.

scholarly journals Infectious safety during primary specialized accreditation in the COVID-19 pandemic

2021 ◽  
pp. 14-20
Author(s):  
Evgeny Germanovich Ripp ◽  
A. R. Fattakhov ◽  
T. M. Ripp ◽  
R. A. Postanogov ◽  
N. M. Iminov ◽  
...  
Keyword(s):  
Medical Education ◽  
Medical Research ◽  
Research Centre ◽  
Face To Face ◽  
Technological Processes ◽  
Specialized Accreditation ◽  
National Medical ◽  
Technical Personnel ◽  
The Face ◽  
Simulation Center

This article is devoted to the organization of the work of the Accreditation and Simulation Center of the Institute of Medical Education of the Almazov National Medical Research Centre during the primary specialized accreditation in the COVID-19 pandemic. Organizational solutions, technological processes and routing of accredited (308 people), support and technical personnel (98 people) and employees of the Accreditation and Simulation Center (14 people) and members of accreditation commissions (67 people) are presented to ensure infectious safety and the effectiveness of the face-to-face practice-oriented stage of accreditation.

scholarly journals Transsphenoidal endoscopic appro ach in the treat ment of spontaneous cerebrospinal fluid (CSF) leak

2019 ◽  
Vol 178 (2) ◽  
pp. 10-14
Author(s):  
V. Y. Cherebillo ◽  
S. A. Karpischenko ◽  
N. S. Puzakov ◽  
O. A. Stancheva
Keyword(s):  
Cerebrospinal Fluid ◽  
Nasal Cavity ◽  
Pathological Condition ◽  
Research Centre ◽  
Csf Leak ◽  
Medical Institute ◽  
Large Defect ◽  
Endoscopic Endonasal ◽  
National Medical ◽  
Treat Ment

Introduction. Spontaneous nasal liquorrhea is a pathological condition associated with defect between nasal cavity and intracranial structures that lead to the expiration of the CSF from the nasal cavity.The objective is to evaluate the effectiveness of endoscopic endonasal approach in the CSF leak treatment.Material and methods. For the period from 2008 to 2018, 38 patients with spontaneous nasal liquorrhea were examined and treated in Pavlov First Saint Petersburg State Medical University, the clinic of neurosurgery of Kirov Medical Institute and Almazov National Medical Research Centre. All patients underwent plastic surgery of the CSF fistula by endoscopic endonasal aproach.Results. Only in 4 cases, there was a large defect, the failure of the closure of which required repeated surgical intervention in 1–2 weeks after the initial operation.Conclusion. The use of autologous tissues (muscle or fat autograft) is the method of choice for repeated surgical plastics of the cerebrospinal fluid fistula or in a large size defect (more than 5 mm).

scholarly journals Orthopedic treatment in cancer patients with maxillofacial pathology

2021 ◽  
Vol 2 (2) ◽  
pp. 22-33
Author(s):  
I. V. Pustovaya ◽  
M. A. Engibaryan ◽  
P. V. Svetitskiy ◽  
I. V. Aedinova ◽  
V. L. Volkova ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Soft Tissues ◽  
Malignant Tumors ◽  
Social Adaptation ◽  
Research Centre ◽  
Orthopedic Treatment ◽  
National Medical ◽  
Upper Jaw ◽  
The Aesthetic

Relevance. Staged orthopedic treatment was used to improve the quality of life of patients who underwent radical maxillofacial surgeries for cancer.Patients and methods. 197 patients receiving treatment for maxillofacial cancer were observed at the Department of head and neck tumors, National Medical Research Centre for Oncology of the Ministry of Health of Russia, in 1998- 2018. All patients underwent radical surgical treatment resulting in postoperative defects of the upper jaw, soft tissues of the zygomatic- buccal-orbital region, nose, or auricle.Results. Removable obturator prostheses with various supporting and retaining elements were made for 159 (80.7 %) patients. Individual facial prostheses were made for 38 (19.3 %) patients: 17 (44.7 %) – external orbital prostheses, 14 (36.8 %) – external nasal prostheses, 6 (15.8 %) – external zygomatic- buccal-orbital prostheses, 1 (2.7 %) – external auricle prosthesis. Combined prostheses were made for 4 patients– removable upper jaw obturator and nose prosthe[1]sis; removable upper jaw obturator and eye prosthesis. Combined prostheses were fixed to each other using magnets. The results of maxillofacial prosthetics were evaluated according to the aesthetic requirements of the patients and their quality of life. Maxillofacial prostheses allowed a complete restoration of chewing, swallowing, and speaking, restored facial deformation, and improved the appearance of patients.Conclusions. Timely and comprehensive orthopedic treatment of patients with postoperative maxillofacial defects after radical surgeries for malignant tumors takes the main place in the complex of rehabilitation measures. Early elimination of extensive defects is aimed at maximum restoration of oral dysfunctions and appearance preservation. The apparent advantages of maxillofacial prostheses involve improvement of social adaptation and the quality of life of patients, which promotes complete rehabilitation and a return to socially useful activities.

scholarly journals Systemic Puppet Therapy in Rehabilitation Practice

2020 ◽  
Vol 99 (5) ◽  
pp. 88-93
Author(s):  
O.A. Lanberg ◽  
L.G. Khayet ◽  
T.V. Kadinskaya
Keyword(s):  
Research Centre ◽  
Face To Face ◽  
National Medical ◽  
Resource Search ◽  
Wide Range ◽  
Analysis And Synthesis ◽  
Scope Of Application ◽  
Puppet Therapy ◽  
Psychological Assistance ◽  
Intellectual Level

The concept of systemic puppet therapy proposed by the authors is described. Therapeutic work with puppets is a promising method of psychological assistance as part of rehabilitation processes. Its insufficient use is due to its low structurality. The phased application of morphological analysis and synthesis made it possible to streamline the known and develop new effective methods of puppet therapy. The proposed systemic puppet therapy is an ordered polymodal set of static (lining on the table or on the floor of a puppet arranged set) and dynamic (presenting history on behalf of the puppet or staging a performance) methods, individual and group methods, face-to-face and remote forms of work, algorithms for their choice.The size, material and design of puppets, quantitative and qualitative composition of their therapeutic set are justified. Methods of puppet therapy of different degree of structuring and depth of exposure for patients with different level of intelligence are described, including category and scope of application of the technique, instructions to the patient, plan of results discussion,transformation procedure providing therapeutic effect. Implementing a polymodal approach, after working with puppets, patients painted, composed and analysed works of literature andart. The field of puppet therapy intersected with the fields of drama-, mask- and art therapy, body-oriented and verbal therapy, psychodrama and system arrangements. Puppet therapy content included work with feelings and emotions, with the process of communication and social roles, with verbal and non-verbal diagnostics and self-diagnostics, with personal features and a system of relationships,with values and needs, with existential problems of patients. Systemic puppet therapy is applicable to a wide range of nosological categories, therapeutic situations, physical condition, intellectual level, gender and age characteristics of patients.The conditions and examples of application of techniques in the National Medical Research Centre of Rehabilitation and Balneology with the tasks of correcting unproductive attitudes and the system of patient relations, correcting perceptions of oneself; capacity-building and resource search; development of a compliance installation and active participation in rehabilitation are given.

scholarly journals Conservative management of early uncomplicated appendicitis in children

2017 ◽  
Vol 4 (3) ◽  
pp. 1024 ◽  
Author(s):  
Sunil Kumar Maini ◽  
Neeraj Kumar Jain ◽  
Manjari Goel Jain ◽  
Vicky Khobragade
Keyword(s):  
Abdominal Pain ◽  
Acute Appendicitis ◽  
Conservative Management ◽  
Medical Management ◽  
Surgical Intervention ◽  
Lower Abdominal Pain ◽  
Primary Treatment ◽  
Research Centre ◽  
Uncomplicated Appendicitis

Background: Right lower abdominal pain management in children is a challenging task for the surgeon. Most of the time right lower abdominal pain ends up in acute appendicitis. For long time appendicetomy was the treatment of choice. However surgical intervention has its own disadvantages such as pain, scarring, adhesions, hernia development and venous thrombosis disease. Anxiety and fear of surgery were also two difficulties in obtaining consent for surgery. Parents often request and insist for medical management. Their unwillingness for surgical intervention was the most important reason for medical management of uncomplicated acute appendicitis.Methods: Our prospective observational study was conducted in the Department of General Surgery, R.K.D.F. Medical College and Research Centre, Bhopal, Madhya Pradesh, India during period of January 2014 to January 2016 and follow up was done till December 2016. Our target group was children under 16 years. A total of 92 children with complaint of right lower abdominal pain attended the hospital for treatment. Routine investigations including ultrasonography of abdomen were performed for all the patients. Out of 92 patients diagnosis of acute appendicitis was made in 74 patients, Surgery was performed in 32 patients, while remaining 42 patients were treated conservatively and the results were analyzed.Results: In this study of 92 patients of pain in right iliac fossa below 16 years, 74 (80.43%) were diagnosed as acute appendicitis. 32 (43.24%) Patients were operated earlier. 42 (56.75%) Patient were treated conservatively. Out of 42 patients, 12 (16.21%) patients were operated within 1 year, 30 (40.54%) Patients didn’t require any surgical intervention during 1 year follow up. In present study, significant role of antibiotic was found in conservative management of acute appendicitis in children. So it can be concluded that conservative management of acute appendicitis in children can be attempted under observation.Conclusions: Antibiotics are both effective and safe as primary treatment for patients with uncomplicated acute appendicitis. Initial antibiotic treatment merits consideration as a primary treatment option for early uncomplicated appendicitis. Appendicectomy should be done but conservative management of acute appendicitis in children can be attempted under observation.

scholarly journals Neuroendocrine neoplasms of kidney

2020 ◽  
pp. 47-51
Author(s):  
D. V. Abbasova ◽  
S. B. Polikarpova ◽  
A. A. Markovich ◽  
V. Yu. Kirsanov ◽  
N. A. Kozlov
Keyword(s):  
Cell Cancer ◽  
Large Cell ◽  
Research Centre ◽  
Neuroendocrine Neoplasms ◽  
Malignant Neoplasms ◽  
Ki 67 ◽  
True Incidence ◽  
National Medical ◽  
Anatomical Localization ◽  
Total Proportion

The most common anatomical localization of neuroendocrine neoplasms (NEN) are the digestive and bronchopulmonary systems, the total proportion of which exceeds 90 % of cases of this group of tumors. In turn, the remaining cases are represented by extremely rare primary neuroendocrine neoplasms of the head and neck, skin, female genital organs, mammary gland, bladder and kidney. Due to the extremely rare observations and the lack of standardized approaches to the diagnosis and treatment of neuroendocrine neoplasms of the kidneys are of significant clinical interest. The true incidence of NENs of the kidney has not yet been established. We carried out a retrospective analysis of patients undergoing treatment in National Medical Research Centre of Oncology n. a. N. N. Blokhin (Moscow, Russia) from 1992 to 2015. According to the results of a sample of patients among registered 12,013 cases of malignant neoplasms of the kidney with NEN of the kidney, the number of morphologically verified cases of NEN of the kidney was 9 cases (0.07 %). Among the patients included in the study group, the main part was represented by highly differentiated neuroendocrine tumors (7 cases; 77.8 %), small cell cancer (1 case; 11.1 %), large cell neuroendocrine cancer (1 case; 11.1 %). The average age of the patients was 51 years (40–63 years; median – 55 years), among which there were 4 women and 5 men. In addition, we conducted an analysis of the clinical, morphological and molecular biological characteristics of tumors with the study and assessment of the grade Ki-67, which was a determining factor in predicting survival and choosing treatment tactics.

scholarly journals Dynamic Aortic Aneurism Risk Factors

2021 ◽  
Author(s):  
Oleg Metsker ◽  
Georgy Kopanitsa ◽  
Olga Irtyuga ◽  
Vladimir Uspenskiy
Keyword(s):  
Risk Factors ◽  
Outpatient Clinic ◽  
Hospital Admissions ◽  
Imaging Techniques ◽  
Screening Method ◽  
Aortic Aneurysms ◽  
Research Centre ◽  
Aortic Dilatation ◽  
National Medical ◽  
Echocardiographic Examination

According to different systematic reviews incidence of thoracic aortic aneurysms (TAA) in the general population is increasing in frequency ranging from 5 to 10.4 per 100000 patients. However, only few studies have illustrated the role of different risk factors in the onset and progression of ascending aortic dilatation. Currently, noninvasive imaging techniques are used to assess the progression rate of aortic and aortic valve disease. Transthoracic (TT) Echocardiographic examination routinely includes evaluation of the aorta It is the most available screening method for diagnosis of proximal aortic dilatation. Since the predominant area of dilation is the proximal aorta, TT-echo is often sufficient for screening. We retrospectively analyzed the ECHO database with 78499 echocardiographic records in the Almazov National Medical Research Centre to identify patients with aneurysm. Detailed information including demographic characteristics, ECHO results and comorbidities were extracted from outpatient clinic and from hospital charts related to hospitalizations occurring within a year before index echocardiography was performed. Comorbid diseases were similarly extracted from outpatient clinic and/or hospital admissions. The classifier showed an AUC-ROC for predicting of aneurism detection after a repeated ECHO at 82%.

scholarly journals A clinical case of multiple primary cancers in a carrier of rare SDK2 and NOTCH2 gene mutations

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Nataliya N. Timoshkina ◽  
Dmitry Y. Gvaldin ◽  
Ekaterina P. Omelchuk ◽  
Larisa N. Vashhenko ◽  
Tatjana V. Ausheva ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Soft Tissues ◽  
Gene Mutations ◽  
Left Breast ◽  
Research Centre ◽  
Multiple Primary Cancers ◽  
Caucasian Woman ◽  
Nucleotide Polymorphisms ◽  
National Medical ◽  
Multiple Primary

Abstract Background Genetic predisposition is one of the risk factors for the development of multiple primary cancers (MPCs), the frequency of which increases and ranges from 2 to 17%. This study describes a combination of rare mutations, rs746551843 in the NOTCH2 gene and rs144933006 in the SDK2 gene, in a woman with breast cancer and leiomyosarcoma without a clearly burdened family history. Case presentation A 55-year-old Caucasian woman received complex treatment on the basis of the National Medical Research Centre for Oncology for left breast cancer and leiomyosarcoma of soft tissues of the left thigh. The patient was referred for consultation with a geneticist. Among direct relatives, a maternal aunt with a history of kidney cancer was not a carrier of the studied single nucleotide polymorphisms (SNPs). The healthy son of the patient inherited both mutations. Conclusion Thus, perhaps in the described case, there is a synergistic effect of two alleles of moderate and low penetrance, which led to the phenotype of multiple primary cancers.

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